Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies

Detalhes bibliográficos
Autor(a) principal: Melo, Alan Lane de
Data de Publicação: 1993
Outros Autores: Machado, Conceição Ribeiro da Silva, Pereira, Leógenes Horácio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/28992
Resumo: Cercariae of Schistosoma mansoni inoculated into the peritoneal cavity of naive mice induced host cell adhesion to their surface, but after 90 minutes the number of adherent cells sharply decreased. The cell detachment is progressive and simultaneous to the cercaria-schistosomule transformation. The histological study showed mainly neutrophils in close contact with the larvae. Mononuclear cells and some eosinophils were occasionally seen surrounding the adherent neutrophils. The scanning electron microscopy showed cells displaying twisted microvilli and several microplicae contacting or spreading over the larval surface, and larvae completely surrounded by clusters of cells. These results suggest that the neutrophils recognize molecules on the cercarial surface which induce their spreading
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spelling Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies Adesão celular às larvas de Schistosoma mansoni na cavidade peritoneal de camundongos normais: estudos histológicos e microscopia eletrônica de varredura Schistosoma mansoniCell adhesionNeutrophilsCercaria Cercariae of Schistosoma mansoni inoculated into the peritoneal cavity of naive mice induced host cell adhesion to their surface, but after 90 minutes the number of adherent cells sharply decreased. The cell detachment is progressive and simultaneous to the cercaria-schistosomule transformation. The histological study showed mainly neutrophils in close contact with the larvae. Mononuclear cells and some eosinophils were occasionally seen surrounding the adherent neutrophils. The scanning electron microscopy showed cells displaying twisted microvilli and several microplicae contacting or spreading over the larval surface, and larvae completely surrounded by clusters of cells. These results suggest that the neutrophils recognize molecules on the cercarial surface which induce their spreading A inoculação de cercárias de Schistosoma mansoni na cavidade peritoneal de camundongos normais induz uma aderência de células do hospedeiro a essas larvas. Essa adesão decresce rapidamente quando a larva infectante transforma-se em esquistossômulo. O destacamento das células é progressivo e simultâneo à transformação. Os métodos histológicos e a microscopia eletrônica de varredura mostraram que o neutrófilo é a célula predominante em estreito contacto com a larva. Células mononucleadas e eosinófilos foram observados rodeando o parasito, usualmente sem estar em contacto direto com a larva. Os resultados indicam que neutrófilos podem reconhecer, na superfície larvária, moléculas que induzem sua adesão e espalhamento. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1993-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/28992Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 No. 1 (1993); 17-22 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 Núm. 1 (1993); 17-22 Revista do Instituto de Medicina Tropical de São Paulo; v. 35 n. 1 (1993); 17-22 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/28992/30849Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessMelo, Alan Lane deMachado, Conceição Ribeiro da SilvaPereira, Leógenes Horácio2012-07-02T01:34:41Zoai:revistas.usp.br:article/28992Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:50:45.241735Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies
Adesão celular às larvas de Schistosoma mansoni na cavidade peritoneal de camundongos normais: estudos histológicos e microscopia eletrônica de varredura
title Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies
spellingShingle Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies
Melo, Alan Lane de
Schistosoma mansoni
Cell adhesion
Neutrophils
Cercaria
title_short Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies
title_full Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies
title_fullStr Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies
title_full_unstemmed Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies
title_sort Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies
author Melo, Alan Lane de
author_facet Melo, Alan Lane de
Machado, Conceição Ribeiro da Silva
Pereira, Leógenes Horácio
author_role author
author2 Machado, Conceição Ribeiro da Silva
Pereira, Leógenes Horácio
author2_role author
author
dc.contributor.author.fl_str_mv Melo, Alan Lane de
Machado, Conceição Ribeiro da Silva
Pereira, Leógenes Horácio
dc.subject.por.fl_str_mv Schistosoma mansoni
Cell adhesion
Neutrophils
Cercaria
topic Schistosoma mansoni
Cell adhesion
Neutrophils
Cercaria
description Cercariae of Schistosoma mansoni inoculated into the peritoneal cavity of naive mice induced host cell adhesion to their surface, but after 90 minutes the number of adherent cells sharply decreased. The cell detachment is progressive and simultaneous to the cercaria-schistosomule transformation. The histological study showed mainly neutrophils in close contact with the larvae. Mononuclear cells and some eosinophils were occasionally seen surrounding the adherent neutrophils. The scanning electron microscopy showed cells displaying twisted microvilli and several microplicae contacting or spreading over the larval surface, and larvae completely surrounded by clusters of cells. These results suggest that the neutrophils recognize molecules on the cercarial surface which induce their spreading
publishDate 1993
dc.date.none.fl_str_mv 1993-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/28992
url https://www.revistas.usp.br/rimtsp/article/view/28992
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/28992/30849
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 No. 1 (1993); 17-22
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 Núm. 1 (1993); 17-22
Revista do Instituto de Medicina Tropical de São Paulo; v. 35 n. 1 (1993); 17-22
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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