Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/151611 |
Resumo: | Knowledge about epidemiological distribution patterns of HIV infection in different geographic regions is relevant to understand the dynamics of the disease in Brazil. This study aims to characterize the epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, from 2005 to 2015. A standardized questionnaire was used to collect clinical-epidemiological, virological, and immunological data from the medical records of all HIV-infected patients (n=539) who were followed at the regional reference center of Jatai, Goias State, Brazil, from 2005 to 2015. We detected the prevalence of male patients and the heterosexual route of transmission, as well as an expressive number of young women infected with HIV. The HIV infection was more prevalent in reproductive ages (55.3%). Most patients presented clinical manifestations related to HIV infection at the time of diagnosis. Twenty-four patients presented coinfection with hepatitis C virus, syphilis, hepatitis B virus, leprosy or Chagas disease. Pneumonia caused by Pneumocystis jirovecii was the most common opportunistic infection, followed by neurotoxoplasmosis, tuberculosis, and neurocryptococcosis. Combined antiretroviral therapy improved CD4+ T-cell counts: the mean CD4+ T-cell counts after treatment was twice as high as those found at the first medical appointment; and highly active antiretroviral therapy promoted viral suppression in a significant number of patients. Considering the increasing distribution of HIV infection to the interior of Brazil, this descriptive study outlines the clinical-epidemiological characteristics of HIV infection in Southwestern Goias and contributes to develop local prevention strategies and public service plans. |
id |
IMT-1_e56643d334ff22b41fcd0e42bed1e060 |
---|---|
oai_identifier_str |
oai:revistas.usp.br:article/151611 |
network_acronym_str |
IMT-1 |
network_name_str |
Revista do Instituto de Medicina Tropical de São Paulo |
repository_id_str |
|
spelling |
Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, BrazilHIV/AIDSEpidemiologyMidwest BrazilKnowledge about epidemiological distribution patterns of HIV infection in different geographic regions is relevant to understand the dynamics of the disease in Brazil. This study aims to characterize the epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, from 2005 to 2015. A standardized questionnaire was used to collect clinical-epidemiological, virological, and immunological data from the medical records of all HIV-infected patients (n=539) who were followed at the regional reference center of Jatai, Goias State, Brazil, from 2005 to 2015. We detected the prevalence of male patients and the heterosexual route of transmission, as well as an expressive number of young women infected with HIV. The HIV infection was more prevalent in reproductive ages (55.3%). Most patients presented clinical manifestations related to HIV infection at the time of diagnosis. Twenty-four patients presented coinfection with hepatitis C virus, syphilis, hepatitis B virus, leprosy or Chagas disease. Pneumonia caused by Pneumocystis jirovecii was the most common opportunistic infection, followed by neurotoxoplasmosis, tuberculosis, and neurocryptococcosis. Combined antiretroviral therapy improved CD4+ T-cell counts: the mean CD4+ T-cell counts after treatment was twice as high as those found at the first medical appointment; and highly active antiretroviral therapy promoted viral suppression in a significant number of patients. Considering the increasing distribution of HIV infection to the interior of Brazil, this descriptive study outlines the clinical-epidemiological characteristics of HIV infection in Southwestern Goias and contributes to develop local prevention strategies and public service plans.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2018-11-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/xmlhttps://www.revistas.usp.br/rimtsp/article/view/151611Revista do Instituto de Medicina Tropical de São Paulo; Vol. 60 (2018); e34Revista do Instituto de Medicina Tropical de São Paulo; Vol. 60 (2018); e34Revista do Instituto de Medicina Tropical de São Paulo; v. 60 (2018); e341678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/151611/148559https://www.revistas.usp.br/rimtsp/article/view/151611/148560Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessDias, Regyane Ferreira GuimarãesBento, Luciana OliveiraTavares, CamilaRanes Filho, HélioSilva, Melisia Adelaide Cesário daMoraes, Luciene CarneiroFreitas-Vilela, Ana AméliaMoreli, Marcos LázaroCardoso, Ludimila Paula Vaz2018-11-07T17:24:58Zoai:revistas.usp.br:article/151611Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:45.146593Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil |
title |
Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil |
spellingShingle |
Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil Dias, Regyane Ferreira Guimarães HIV/AIDS Epidemiology Midwest Brazil |
title_short |
Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil |
title_full |
Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil |
title_fullStr |
Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil |
title_full_unstemmed |
Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil |
title_sort |
Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil |
author |
Dias, Regyane Ferreira Guimarães |
author_facet |
Dias, Regyane Ferreira Guimarães Bento, Luciana Oliveira Tavares, Camila Ranes Filho, Hélio Silva, Melisia Adelaide Cesário da Moraes, Luciene Carneiro Freitas-Vilela, Ana Amélia Moreli, Marcos Lázaro Cardoso, Ludimila Paula Vaz |
author_role |
author |
author2 |
Bento, Luciana Oliveira Tavares, Camila Ranes Filho, Hélio Silva, Melisia Adelaide Cesário da Moraes, Luciene Carneiro Freitas-Vilela, Ana Amélia Moreli, Marcos Lázaro Cardoso, Ludimila Paula Vaz |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Dias, Regyane Ferreira Guimarães Bento, Luciana Oliveira Tavares, Camila Ranes Filho, Hélio Silva, Melisia Adelaide Cesário da Moraes, Luciene Carneiro Freitas-Vilela, Ana Amélia Moreli, Marcos Lázaro Cardoso, Ludimila Paula Vaz |
dc.subject.por.fl_str_mv |
HIV/AIDS Epidemiology Midwest Brazil |
topic |
HIV/AIDS Epidemiology Midwest Brazil |
description |
Knowledge about epidemiological distribution patterns of HIV infection in different geographic regions is relevant to understand the dynamics of the disease in Brazil. This study aims to characterize the epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, from 2005 to 2015. A standardized questionnaire was used to collect clinical-epidemiological, virological, and immunological data from the medical records of all HIV-infected patients (n=539) who were followed at the regional reference center of Jatai, Goias State, Brazil, from 2005 to 2015. We detected the prevalence of male patients and the heterosexual route of transmission, as well as an expressive number of young women infected with HIV. The HIV infection was more prevalent in reproductive ages (55.3%). Most patients presented clinical manifestations related to HIV infection at the time of diagnosis. Twenty-four patients presented coinfection with hepatitis C virus, syphilis, hepatitis B virus, leprosy or Chagas disease. Pneumonia caused by Pneumocystis jirovecii was the most common opportunistic infection, followed by neurotoxoplasmosis, tuberculosis, and neurocryptococcosis. Combined antiretroviral therapy improved CD4+ T-cell counts: the mean CD4+ T-cell counts after treatment was twice as high as those found at the first medical appointment; and highly active antiretroviral therapy promoted viral suppression in a significant number of patients. Considering the increasing distribution of HIV infection to the interior of Brazil, this descriptive study outlines the clinical-epidemiological characteristics of HIV infection in Southwestern Goias and contributes to develop local prevention strategies and public service plans. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-11-07 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/151611 |
url |
https://www.revistas.usp.br/rimtsp/article/view/151611 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/151611/148559 https://www.revistas.usp.br/rimtsp/article/view/151611/148560 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/xml |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 60 (2018); e34 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 60 (2018); e34 Revista do Instituto de Medicina Tropical de São Paulo; v. 60 (2018); e34 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
_version_ |
1798951652147855360 |