Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama

Detalhes bibliográficos
Autor(a) principal: Brondi, Luiz Antonio Guimarães
Data de Publicação: 2023
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3195
Resumo: There is no doubt about the importance of axillary lymph nodes in the treatment and prognosis of breast cancer in order to observe this undera surgical point of view, 151 mastectomy specimens were studied (104 with Halsted-Meyer and 47 with Patey-Dyson techniques). A total of 5,015 axillary nodes were dissected and the median number per axilla was 33.2 nodes. No special method for searching nodes in surgical specimens was used. There was no significant difference between the median number of lymph nodes present in axilla with one or another surgical technique. The lymph nodes were divided according to the drainage levels and their larger diameter There was a correlation between node diameter and its histological compromising and we concluded that node diameter can be another prognostic indicator to breast cancer The small lymph nodes (less than 0.5 cm) were found in all drainage levels, inversely in relation to the nodes with more than 2cm: they were almost exclusively found at level I. Othervvise, these latest lymph nodes present na histologic positive rate higher than the other ones. The false negatives were 22.5% and were higher among cases with initial stages. The conviction about the histologic positiveness of axillary lymph can only be obtained if all dissected nodes are examined. That will be possible after a good axillary dissection, including remotion of pectoralis minor muscle. Therefore, conservative techniques with preservation of both pectoralis muscles, carry an incomplete axillary dissection. Histologic positivity of lymph nodes present at superior leveis without the compromising of the first level was rare as well as, it was also rare histologic positivity of small lymph nodes without involvement of the larger lymph nodes. A specific lymph node group was described, one of the highest level, called PARA-CEPHALIC GROUP, found in 34 specimens (22.5%). Clinically negatives nodes with less than 0.5cm in diameter but histologically positive can be called MINIMAL AXILLARY BREAST METASTASES.
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spelling Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da MamaCâncer da MamaLinfadenectomia AxilarBreast CancerAxillar LymphadenectomyThere is no doubt about the importance of axillary lymph nodes in the treatment and prognosis of breast cancer in order to observe this undera surgical point of view, 151 mastectomy specimens were studied (104 with Halsted-Meyer and 47 with Patey-Dyson techniques). A total of 5,015 axillary nodes were dissected and the median number per axilla was 33.2 nodes. No special method for searching nodes in surgical specimens was used. There was no significant difference between the median number of lymph nodes present in axilla with one or another surgical technique. The lymph nodes were divided according to the drainage levels and their larger diameter There was a correlation between node diameter and its histological compromising and we concluded that node diameter can be another prognostic indicator to breast cancer The small lymph nodes (less than 0.5 cm) were found in all drainage levels, inversely in relation to the nodes with more than 2cm: they were almost exclusively found at level I. Othervvise, these latest lymph nodes present na histologic positive rate higher than the other ones. The false negatives were 22.5% and were higher among cases with initial stages. The conviction about the histologic positiveness of axillary lymph can only be obtained if all dissected nodes are examined. That will be possible after a good axillary dissection, including remotion of pectoralis minor muscle. Therefore, conservative techniques with preservation of both pectoralis muscles, carry an incomplete axillary dissection. Histologic positivity of lymph nodes present at superior leveis without the compromising of the first level was rare as well as, it was also rare histologic positivity of small lymph nodes without involvement of the larger lymph nodes. A specific lymph node group was described, one of the highest level, called PARA-CEPHALIC GROUP, found in 34 specimens (22.5%). Clinically negatives nodes with less than 0.5cm in diameter but histologically positive can be called MINIMAL AXILLARY BREAST METASTASES.Não existem dúvidas quanto à importância dos linfonodos axilares no prognóstico e tratamento do câncer da mama. Em 151 mastectomias realizadas, empregando-se as técnicas de Halsted-Meyer (104 casos) e de Patey-Dyson (47 casos), encontrou-se um total de 5.015 linfonodos axilares, com a média de 33,2 por axila. Não houve diferença significativa entre o número médio de linfonodos encontrados na axila, tanto com uma quanto com outra técnica de mastectomia. Os linfonodos foram divididos de acordo com os níveis de drenagem axilar e de acordo com os seus maiores diâmetros. Observou-se uma estreita correlação entre o diâmetro de cada um deles e o seu comprometimento histológico, de onde se conclui que esse parâmetro pode ser considerado como outro indicador prognóstico para o câncer da mama. Os pequenos linfonodos (0,5cm ou menos) estavam presentes em todos os níveis, ao contrário do que ocorreu com aqueles maiores que 2cm de diâmetro, encontrados quase exclusivamente no primeiro nível de drenagem axilar. Por outro lado, estes últimos apresentaram uma taxa de comprometimento histológico mais elevada que os demais. Observou-se uma taxa de falso negativo de 22,5%, a qual foi mais elevada entre os casos mais iniciais de estadiamento da moléstia. O comportamento histológico da axila só poderá ser comprovado se todos os linfonodos encontrados forem examinados, o que será possível após um bom esvaziamento axilar, incluindo a retirada do músculo peitoral menor. Dessa maneira, cirurgias mais conservadoras, com preservação dos músculos peitorais, apenas levarão a uma linfadenectomia axilar incompleta. Foi muito raro o comprometimento de linfonodos situados em níveis superiores sem que o primeiro nível estivesse comprometido. Assim como foi raro encontrar linfonodos pequenos comprometidos sem que os maiores estivessem histologicamente positivos. Foi descrito um grupo de linfonodos, considerado uma das cadeias mais altas da axila, denominado GRUPO PARACEFÁLICO, encontrado em 34 mastectomias (22,5%). Os linfonodos menores que 0,5cm de diâmetro, clinicamente não detectáveis, mas histologicamente com prometidos, foram denominados METASTASES AXILARES MINIMAS DA MAMA.INCA2023-08-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/319510.32635/2176-9745.RBC.1987v33n2.3195Revista Brasileira de Cancerologia; Vol. 33 No. 2 (1987): June; 119-126Revista Brasileira de Cancerologia; Vol. 33 Núm. 2 (1987): jun.; 119-126Revista Brasileira de Cancerologia; v. 33 n. 2 (1987): jun.; 119-1262176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/3195/2048https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBrondi, Luiz Antonio Guimarães2023-08-04T18:36:14Zoai:rbc.inca.gov.br:article/3195Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-08-04T18:36:14Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama
title Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama
spellingShingle Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama
Brondi, Luiz Antonio Guimarães
Câncer da Mama
Linfadenectomia Axilar
Breast Cancer
Axillar Lymphadenectomy
title_short Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama
title_full Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama
title_fullStr Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama
title_full_unstemmed Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama
title_sort Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama
author Brondi, Luiz Antonio Guimarães
author_facet Brondi, Luiz Antonio Guimarães
author_role author
dc.contributor.author.fl_str_mv Brondi, Luiz Antonio Guimarães
dc.subject.por.fl_str_mv Câncer da Mama
Linfadenectomia Axilar
Breast Cancer
Axillar Lymphadenectomy
topic Câncer da Mama
Linfadenectomia Axilar
Breast Cancer
Axillar Lymphadenectomy
description There is no doubt about the importance of axillary lymph nodes in the treatment and prognosis of breast cancer in order to observe this undera surgical point of view, 151 mastectomy specimens were studied (104 with Halsted-Meyer and 47 with Patey-Dyson techniques). A total of 5,015 axillary nodes were dissected and the median number per axilla was 33.2 nodes. No special method for searching nodes in surgical specimens was used. There was no significant difference between the median number of lymph nodes present in axilla with one or another surgical technique. The lymph nodes were divided according to the drainage levels and their larger diameter There was a correlation between node diameter and its histological compromising and we concluded that node diameter can be another prognostic indicator to breast cancer The small lymph nodes (less than 0.5 cm) were found in all drainage levels, inversely in relation to the nodes with more than 2cm: they were almost exclusively found at level I. Othervvise, these latest lymph nodes present na histologic positive rate higher than the other ones. The false negatives were 22.5% and were higher among cases with initial stages. The conviction about the histologic positiveness of axillary lymph can only be obtained if all dissected nodes are examined. That will be possible after a good axillary dissection, including remotion of pectoralis minor muscle. Therefore, conservative techniques with preservation of both pectoralis muscles, carry an incomplete axillary dissection. Histologic positivity of lymph nodes present at superior leveis without the compromising of the first level was rare as well as, it was also rare histologic positivity of small lymph nodes without involvement of the larger lymph nodes. A specific lymph node group was described, one of the highest level, called PARA-CEPHALIC GROUP, found in 34 specimens (22.5%). Clinically negatives nodes with less than 0.5cm in diameter but histologically positive can be called MINIMAL AXILLARY BREAST METASTASES.
publishDate 2023
dc.date.none.fl_str_mv 2023-08-04
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dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3195/2048
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dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 33 No. 2 (1987): June; 119-126
Revista Brasileira de Cancerologia; Vol. 33 Núm. 2 (1987): jun.; 119-126
Revista Brasileira de Cancerologia; v. 33 n. 2 (1987): jun.; 119-126
2176-9745
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instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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