Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
DOI: | 10.32635/2176-9745.RBC.1987v33n2.3195 |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/3195 |
Resumo: | There is no doubt about the importance of axillary lymph nodes in the treatment and prognosis of breast cancer in order to observe this undera surgical point of view, 151 mastectomy specimens were studied (104 with Halsted-Meyer and 47 with Patey-Dyson techniques). A total of 5,015 axillary nodes were dissected and the median number per axilla was 33.2 nodes. No special method for searching nodes in surgical specimens was used. There was no significant difference between the median number of lymph nodes present in axilla with one or another surgical technique. The lymph nodes were divided according to the drainage levels and their larger diameter There was a correlation between node diameter and its histological compromising and we concluded that node diameter can be another prognostic indicator to breast cancer The small lymph nodes (less than 0.5 cm) were found in all drainage levels, inversely in relation to the nodes with more than 2cm: they were almost exclusively found at level I. Othervvise, these latest lymph nodes present na histologic positive rate higher than the other ones. The false negatives were 22.5% and were higher among cases with initial stages. The conviction about the histologic positiveness of axillary lymph can only be obtained if all dissected nodes are examined. That will be possible after a good axillary dissection, including remotion of pectoralis minor muscle. Therefore, conservative techniques with preservation of both pectoralis muscles, carry an incomplete axillary dissection. Histologic positivity of lymph nodes present at superior leveis without the compromising of the first level was rare as well as, it was also rare histologic positivity of small lymph nodes without involvement of the larger lymph nodes. A specific lymph node group was described, one of the highest level, called PARA-CEPHALIC GROUP, found in 34 specimens (22.5%). Clinically negatives nodes with less than 0.5cm in diameter but histologically positive can be called MINIMAL AXILLARY BREAST METASTASES. |
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Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da MamaCâncer da MamaLinfadenectomia AxilarBreast CancerAxillar LymphadenectomyThere is no doubt about the importance of axillary lymph nodes in the treatment and prognosis of breast cancer in order to observe this undera surgical point of view, 151 mastectomy specimens were studied (104 with Halsted-Meyer and 47 with Patey-Dyson techniques). A total of 5,015 axillary nodes were dissected and the median number per axilla was 33.2 nodes. No special method for searching nodes in surgical specimens was used. There was no significant difference between the median number of lymph nodes present in axilla with one or another surgical technique. The lymph nodes were divided according to the drainage levels and their larger diameter There was a correlation between node diameter and its histological compromising and we concluded that node diameter can be another prognostic indicator to breast cancer The small lymph nodes (less than 0.5 cm) were found in all drainage levels, inversely in relation to the nodes with more than 2cm: they were almost exclusively found at level I. Othervvise, these latest lymph nodes present na histologic positive rate higher than the other ones. The false negatives were 22.5% and were higher among cases with initial stages. The conviction about the histologic positiveness of axillary lymph can only be obtained if all dissected nodes are examined. That will be possible after a good axillary dissection, including remotion of pectoralis minor muscle. Therefore, conservative techniques with preservation of both pectoralis muscles, carry an incomplete axillary dissection. Histologic positivity of lymph nodes present at superior leveis without the compromising of the first level was rare as well as, it was also rare histologic positivity of small lymph nodes without involvement of the larger lymph nodes. A specific lymph node group was described, one of the highest level, called PARA-CEPHALIC GROUP, found in 34 specimens (22.5%). Clinically negatives nodes with less than 0.5cm in diameter but histologically positive can be called MINIMAL AXILLARY BREAST METASTASES.Não existem dúvidas quanto à importância dos linfonodos axilares no prognóstico e tratamento do câncer da mama. Em 151 mastectomias realizadas, empregando-se as técnicas de Halsted-Meyer (104 casos) e de Patey-Dyson (47 casos), encontrou-se um total de 5.015 linfonodos axilares, com a média de 33,2 por axila. Não houve diferença significativa entre o número médio de linfonodos encontrados na axila, tanto com uma quanto com outra técnica de mastectomia. Os linfonodos foram divididos de acordo com os níveis de drenagem axilar e de acordo com os seus maiores diâmetros. Observou-se uma estreita correlação entre o diâmetro de cada um deles e o seu comprometimento histológico, de onde se conclui que esse parâmetro pode ser considerado como outro indicador prognóstico para o câncer da mama. Os pequenos linfonodos (0,5cm ou menos) estavam presentes em todos os níveis, ao contrário do que ocorreu com aqueles maiores que 2cm de diâmetro, encontrados quase exclusivamente no primeiro nível de drenagem axilar. Por outro lado, estes últimos apresentaram uma taxa de comprometimento histológico mais elevada que os demais. Observou-se uma taxa de falso negativo de 22,5%, a qual foi mais elevada entre os casos mais iniciais de estadiamento da moléstia. O comportamento histológico da axila só poderá ser comprovado se todos os linfonodos encontrados forem examinados, o que será possível após um bom esvaziamento axilar, incluindo a retirada do músculo peitoral menor. Dessa maneira, cirurgias mais conservadoras, com preservação dos músculos peitorais, apenas levarão a uma linfadenectomia axilar incompleta. Foi muito raro o comprometimento de linfonodos situados em níveis superiores sem que o primeiro nível estivesse comprometido. Assim como foi raro encontrar linfonodos pequenos comprometidos sem que os maiores estivessem histologicamente positivos. Foi descrito um grupo de linfonodos, considerado uma das cadeias mais altas da axila, denominado GRUPO PARACEFÁLICO, encontrado em 34 mastectomias (22,5%). Os linfonodos menores que 0,5cm de diâmetro, clinicamente não detectáveis, mas histologicamente com prometidos, foram denominados METASTASES AXILARES MINIMAS DA MAMA.INCA2023-08-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/319510.32635/2176-9745.RBC.1987v33n2.3195Revista Brasileira de Cancerologia; Vol. 33 No. 2 (1987): June; 119-126Revista Brasileira de Cancerologia; Vol. 33 Núm. 2 (1987): jun.; 119-126Revista Brasileira de Cancerologia; v. 33 n. 2 (1987): jun.; 119-1262176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/3195/2048https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBrondi, Luiz Antonio Guimarães2023-08-04T18:36:14Zoai:rbc.inca.gov.br:article/3195Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-08-04T18:36:14Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama |
title |
Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama |
spellingShingle |
Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama Brondi, Luiz Antonio Guimarães Câncer da Mama Linfadenectomia Axilar Breast Cancer Axillar Lymphadenectomy Brondi, Luiz Antonio Guimarães Câncer da Mama Linfadenectomia Axilar Breast Cancer Axillar Lymphadenectomy |
title_short |
Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama |
title_full |
Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama |
title_fullStr |
Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama |
title_full_unstemmed |
Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama |
title_sort |
Importância da Linfadenectomia Axilar no Tratamento Cirúrgico do Câncer da Mama |
author |
Brondi, Luiz Antonio Guimarães |
author_facet |
Brondi, Luiz Antonio Guimarães Brondi, Luiz Antonio Guimarães |
author_role |
author |
dc.contributor.author.fl_str_mv |
Brondi, Luiz Antonio Guimarães |
dc.subject.por.fl_str_mv |
Câncer da Mama Linfadenectomia Axilar Breast Cancer Axillar Lymphadenectomy |
topic |
Câncer da Mama Linfadenectomia Axilar Breast Cancer Axillar Lymphadenectomy |
description |
There is no doubt about the importance of axillary lymph nodes in the treatment and prognosis of breast cancer in order to observe this undera surgical point of view, 151 mastectomy specimens were studied (104 with Halsted-Meyer and 47 with Patey-Dyson techniques). A total of 5,015 axillary nodes were dissected and the median number per axilla was 33.2 nodes. No special method for searching nodes in surgical specimens was used. There was no significant difference between the median number of lymph nodes present in axilla with one or another surgical technique. The lymph nodes were divided according to the drainage levels and their larger diameter There was a correlation between node diameter and its histological compromising and we concluded that node diameter can be another prognostic indicator to breast cancer The small lymph nodes (less than 0.5 cm) were found in all drainage levels, inversely in relation to the nodes with more than 2cm: they were almost exclusively found at level I. Othervvise, these latest lymph nodes present na histologic positive rate higher than the other ones. The false negatives were 22.5% and were higher among cases with initial stages. The conviction about the histologic positiveness of axillary lymph can only be obtained if all dissected nodes are examined. That will be possible after a good axillary dissection, including remotion of pectoralis minor muscle. Therefore, conservative techniques with preservation of both pectoralis muscles, carry an incomplete axillary dissection. Histologic positivity of lymph nodes present at superior leveis without the compromising of the first level was rare as well as, it was also rare histologic positivity of small lymph nodes without involvement of the larger lymph nodes. A specific lymph node group was described, one of the highest level, called PARA-CEPHALIC GROUP, found in 34 specimens (22.5%). Clinically negatives nodes with less than 0.5cm in diameter but histologically positive can be called MINIMAL AXILLARY BREAST METASTASES. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-08-04 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigos, Avaliado pelos pares |
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article |
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https://rbc.inca.gov.br/index.php/revista/article/view/3195 10.32635/2176-9745.RBC.1987v33n2.3195 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/3195 |
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10.32635/2176-9745.RBC.1987v33n2.3195 |
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https://rbc.inca.gov.br/index.php/revista/article/view/3195/2048 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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INCA |
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Revista Brasileira de Cancerologia; Vol. 33 No. 2 (1987): June; 119-126 Revista Brasileira de Cancerologia; Vol. 33 Núm. 2 (1987): jun.; 119-126 Revista Brasileira de Cancerologia; v. 33 n. 2 (1987): jun.; 119-126 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
instname_str |
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
instacron_str |
INCA |
institution |
INCA |
reponame_str |
Revista Brasileira de Cancerologia (Online) |
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Revista Brasileira de Cancerologia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
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rbc@inca.gov.br |
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dc.identifier.doi.none.fl_str_mv |
10.32635/2176-9745.RBC.1987v33n2.3195 |