Primary Ovarian Choriocarcinoma: Case Report in a 10-year-old Patient

Detalhes bibliográficos
Autor(a) principal: Santos, Daniela Moreira
Data de Publicação: 2009
Outros Autores: Peruchi, Fernanda Lazzarine, Miranda, João Nestor Rodrigues, Motta, Luciene Lage da, Chambô Filho, Antônio
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/1676
Resumo: The primary ovarian choriocarcinoma is a rare tumor originated from germ cells and occurs mostly associated with other tumors originated from germ cells as well. This case report describes a primary ovarian choriocarcinoma in a 10-year-old female who presentedepisodes of vaginal bleeding and abdominal enlargement. After titer, tumoral markers showed high levels of Beta-HCG and CA-125, as well as normal Alpha-fetoprotein. The patient had to undergo abdominal ultrasonography and median laparotomy respectively. The histopathological and immunohistochemical analysis were compatible with the primary ovarian choriocarcinoma clinical diagnose. After surgery, the patient died in the following day due to tumor emboli from lung neoplasms. Thus, it was concluded that these neoplasms are very aggressive, cause premature metastasis in most cases and present unfavorable prognosis, mainly in youths under 20 years old.
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spelling Primary Ovarian Choriocarcinoma: Case Report in a 10-year-old PatientCoriocarcinoma Primário de Ovário: Relato de um Caso em Paciente de 10 Anos de IdadeCoriocarcinomaNeoplasias ovarianasNeoplasias embrionárias de células germinativasChoriocarcinomaOvarian neoplasmsNeoplasms, germ cell and embryonalThe primary ovarian choriocarcinoma is a rare tumor originated from germ cells and occurs mostly associated with other tumors originated from germ cells as well. This case report describes a primary ovarian choriocarcinoma in a 10-year-old female who presentedepisodes of vaginal bleeding and abdominal enlargement. After titer, tumoral markers showed high levels of Beta-HCG and CA-125, as well as normal Alpha-fetoprotein. The patient had to undergo abdominal ultrasonography and median laparotomy respectively. The histopathological and immunohistochemical analysis were compatible with the primary ovarian choriocarcinoma clinical diagnose. After surgery, the patient died in the following day due to tumor emboli from lung neoplasms. Thus, it was concluded that these neoplasms are very aggressive, cause premature metastasis in most cases and present unfavorable prognosis, mainly in youths under 20 years old.O coriocarcinoma primário de ovário é um tumor raro que se origina de células germinativas, apresentando-se, na maioria das vezes, associado a outros tumores também de origem de células germinativas. Será descrito um caso de coriocarcinoma primário de ovário em uma menina de 10 anos que apresentava um quadro de sangramento vaginal e distensão abdominal. Após serem dosados os marcadores tumorais, que mostraram níveis de beta-HCG (gonadotrofina coriônica humana) e CA-125 altos, e alfafetoproteína normal, e ser realizado ultrassonografia abdominal, a paciente foi submetida a tratamento cirúrgico. O exame histopatológico da peça cirúrgica e a imunohistoquímica foram compatíveis com diagnóstico de coriocarcinoma primário de ovário. Depois da cirurgia, a paciente evoluiu mal, indo a óbito no primeiro dia de pós-operatório devido a uma embolia tumoral pulmonar. Concluiu-se, então, que essa neoplasia é bastante agressiva, causando metástase precoce na maioria dos casos e apresentando prognóstico desfavorável, principalmente em jovens abaixo de 20 anos de idade.INCA2009-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de Casoapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/167610.32635/2176-9745.RBC.2009v55n1.1676Revista Brasileira de Cancerologia; Vol. 55 No. 1 (2009): Jan./Feb;/Mar.; 49-53Revista Brasileira de Cancerologia; Vol. 55 Núm. 1 (2009): ene./feb./mar.; 49-53Revista Brasileira de Cancerologia; v. 55 n. 1 (2009): jan./fev./mar.; 49-532176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/1676/987Santos, Daniela Moreira Peruchi, Fernanda Lazzarine Miranda, João Nestor Rodrigues Motta, Luciene Lage da Chambô Filho, Antônio info:eu-repo/semantics/openAccess2021-11-29T20:21:40Zoai:rbc.inca.gov.br:article/1676Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:21:40Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Primary Ovarian Choriocarcinoma: Case Report in a 10-year-old Patient
Coriocarcinoma Primário de Ovário: Relato de um Caso em Paciente de 10 Anos de Idade
title Primary Ovarian Choriocarcinoma: Case Report in a 10-year-old Patient
spellingShingle Primary Ovarian Choriocarcinoma: Case Report in a 10-year-old Patient
Santos, Daniela Moreira
Coriocarcinoma
Neoplasias ovarianas
Neoplasias embrionárias de células germinativas
Choriocarcinoma
Ovarian neoplasms
Neoplasms, germ cell and embryonal
title_short Primary Ovarian Choriocarcinoma: Case Report in a 10-year-old Patient
title_full Primary Ovarian Choriocarcinoma: Case Report in a 10-year-old Patient
title_fullStr Primary Ovarian Choriocarcinoma: Case Report in a 10-year-old Patient
title_full_unstemmed Primary Ovarian Choriocarcinoma: Case Report in a 10-year-old Patient
title_sort Primary Ovarian Choriocarcinoma: Case Report in a 10-year-old Patient
author Santos, Daniela Moreira
author_facet Santos, Daniela Moreira
Peruchi, Fernanda Lazzarine
Miranda, João Nestor Rodrigues
Motta, Luciene Lage da
Chambô Filho, Antônio
author_role author
author2 Peruchi, Fernanda Lazzarine
Miranda, João Nestor Rodrigues
Motta, Luciene Lage da
Chambô Filho, Antônio
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santos, Daniela Moreira
Peruchi, Fernanda Lazzarine
Miranda, João Nestor Rodrigues
Motta, Luciene Lage da
Chambô Filho, Antônio
dc.subject.por.fl_str_mv Coriocarcinoma
Neoplasias ovarianas
Neoplasias embrionárias de células germinativas
Choriocarcinoma
Ovarian neoplasms
Neoplasms, germ cell and embryonal
topic Coriocarcinoma
Neoplasias ovarianas
Neoplasias embrionárias de células germinativas
Choriocarcinoma
Ovarian neoplasms
Neoplasms, germ cell and embryonal
description The primary ovarian choriocarcinoma is a rare tumor originated from germ cells and occurs mostly associated with other tumors originated from germ cells as well. This case report describes a primary ovarian choriocarcinoma in a 10-year-old female who presentedepisodes of vaginal bleeding and abdominal enlargement. After titer, tumoral markers showed high levels of Beta-HCG and CA-125, as well as normal Alpha-fetoprotein. The patient had to undergo abdominal ultrasonography and median laparotomy respectively. The histopathological and immunohistochemical analysis were compatible with the primary ovarian choriocarcinoma clinical diagnose. After surgery, the patient died in the following day due to tumor emboli from lung neoplasms. Thus, it was concluded that these neoplasms are very aggressive, cause premature metastasis in most cases and present unfavorable prognosis, mainly in youths under 20 years old.
publishDate 2009
dc.date.none.fl_str_mv 2009-03-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Relato de Caso
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1676
10.32635/2176-9745.RBC.2009v55n1.1676
url https://rbc.inca.gov.br/index.php/revista/article/view/1676
identifier_str_mv 10.32635/2176-9745.RBC.2009v55n1.1676
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1676/987
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 55 No. 1 (2009): Jan./Feb;/Mar.; 49-53
Revista Brasileira de Cancerologia; Vol. 55 Núm. 1 (2009): ene./feb./mar.; 49-53
Revista Brasileira de Cancerologia; v. 55 n. 1 (2009): jan./fev./mar.; 49-53
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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