Amitriptyline for Phantom-limb Pain Prevention

Detalhes bibliográficos
Autor(a) principal: Silva, Flavia Claro da
Data de Publicação: 2008
Outros Autores: Moreno, Fabíola Caó de Barros, Bender, Paulo Francisco Mascarenhas, Carvalho, Carmen Dulce Barros de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/1688
Resumo: Phantom-limb pain is a common sequela of amputation. Its etiology is not well known yet. Central changes seem to be a major determinant of phantom-limb pain, however peripheral and psychological factors may contribute to it. Among all of pharmacological interventions, tricyclic antidepressants seem to be one of the treatments of choice, although there have been no controlled studies of these agents for the approach of phantom-limb pain. Besides, tricyclic antidepressants are worldwide used in the treatment of a great variety of pain syndromes, especially those which have neurophatic aspects. The purpose of this opinion article is to propose the use of the tricyclic antidepressants to the prevention of the phantom-limb pain phenomena.
id INCA-1_1913bc42546efbaac1eb8d463872a171
oai_identifier_str oai:rbc.inca.gov.br:article/1688
network_acronym_str INCA-1
network_name_str Revista Brasileira de Cancerologia (Online)
repository_id_str
spelling Amitriptyline for Phantom-limb Pain PreventionPrevenção da Dor Fantasma com Uso de Cloridrato de AmitriptilinaDorMembro-fantasmaAntidepressivos tricíclicosPainPhantom limbAntidepressive agents, tricyclicPhantom-limb pain is a common sequela of amputation. Its etiology is not well known yet. Central changes seem to be a major determinant of phantom-limb pain, however peripheral and psychological factors may contribute to it. Among all of pharmacological interventions, tricyclic antidepressants seem to be one of the treatments of choice, although there have been no controlled studies of these agents for the approach of phantom-limb pain. Besides, tricyclic antidepressants are worldwide used in the treatment of a great variety of pain syndromes, especially those which have neurophatic aspects. The purpose of this opinion article is to propose the use of the tricyclic antidepressants to the prevention of the phantom-limb pain phenomena.A dor do membro amputado é uma seqüela comum da amputação de um membro do corpo e, até os dias de hoje, a sua etiologia não está totalmente esclarecida. Embora o seu principal mecanismo de ação seja as alterações no Sistema Nervoso Central (SNC), se admite que haja também influência dos mecanismos periféricos e psicológicos. O uso dos adjuvantes, principalmente os antidepressivos tricíclicos (ADT), no tratamento deste tipo de dor crônica, é amplamente realizado, porém sem resultados consistentes ou com comprovação científica. Contudo, o uso dos ADT mostra-se eficaz para tratamento de diversas síndromes álgicas, em parte devido à sua ação central de inibição do transporte neuronal e ao bloqueio do transporte de serotonina nas vias supressoras, fato que antecede o seu mecanismo antidepressivo ou psicotrópico propriamente dito. Este artigo de opinião se destina a propor o uso dos ADT como droga preventiva no tratamento da dor do membro fantasma.INCA2008-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigo de opniãoapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/168810.32635/2176-9745.RBC.2008v54n4.1688Revista Brasileira de Cancerologia; Vol. 54 No. 4 (2008): Oct./Nov./Dec.; 345-349Revista Brasileira de Cancerologia; Vol. 54 Núm. 4 (2008): oct./nov.dic.; 345-349Revista Brasileira de Cancerologia; v. 54 n. 4 (2008): out./nov./dez.; 345-3492176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/1688/997Silva, Flavia Claro da Moreno, Fabíola Caó de Barros Bender, Paulo Francisco Mascarenhas Carvalho, Carmen Dulce Barros de info:eu-repo/semantics/openAccess2021-11-29T20:22:15Zoai:rbc.inca.gov.br:article/1688Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:22:15Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Amitriptyline for Phantom-limb Pain Prevention
Prevenção da Dor Fantasma com Uso de Cloridrato de Amitriptilina
title Amitriptyline for Phantom-limb Pain Prevention
spellingShingle Amitriptyline for Phantom-limb Pain Prevention
Silva, Flavia Claro da
Dor
Membro-fantasma
Antidepressivos tricíclicos
Pain
Phantom limb
Antidepressive agents, tricyclic
title_short Amitriptyline for Phantom-limb Pain Prevention
title_full Amitriptyline for Phantom-limb Pain Prevention
title_fullStr Amitriptyline for Phantom-limb Pain Prevention
title_full_unstemmed Amitriptyline for Phantom-limb Pain Prevention
title_sort Amitriptyline for Phantom-limb Pain Prevention
author Silva, Flavia Claro da
author_facet Silva, Flavia Claro da
Moreno, Fabíola Caó de Barros
Bender, Paulo Francisco Mascarenhas
Carvalho, Carmen Dulce Barros de
author_role author
author2 Moreno, Fabíola Caó de Barros
Bender, Paulo Francisco Mascarenhas
Carvalho, Carmen Dulce Barros de
author2_role author
author
author
dc.contributor.author.fl_str_mv Silva, Flavia Claro da
Moreno, Fabíola Caó de Barros
Bender, Paulo Francisco Mascarenhas
Carvalho, Carmen Dulce Barros de
dc.subject.por.fl_str_mv Dor
Membro-fantasma
Antidepressivos tricíclicos
Pain
Phantom limb
Antidepressive agents, tricyclic
topic Dor
Membro-fantasma
Antidepressivos tricíclicos
Pain
Phantom limb
Antidepressive agents, tricyclic
description Phantom-limb pain is a common sequela of amputation. Its etiology is not well known yet. Central changes seem to be a major determinant of phantom-limb pain, however peripheral and psychological factors may contribute to it. Among all of pharmacological interventions, tricyclic antidepressants seem to be one of the treatments of choice, although there have been no controlled studies of these agents for the approach of phantom-limb pain. Besides, tricyclic antidepressants are worldwide used in the treatment of a great variety of pain syndromes, especially those which have neurophatic aspects. The purpose of this opinion article is to propose the use of the tricyclic antidepressants to the prevention of the phantom-limb pain phenomena.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigo de opnião
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1688
10.32635/2176-9745.RBC.2008v54n4.1688
url https://rbc.inca.gov.br/index.php/revista/article/view/1688
identifier_str_mv 10.32635/2176-9745.RBC.2008v54n4.1688
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1688/997
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 54 No. 4 (2008): Oct./Nov./Dec.; 345-349
Revista Brasileira de Cancerologia; Vol. 54 Núm. 4 (2008): oct./nov.dic.; 345-349
Revista Brasileira de Cancerologia; v. 54 n. 4 (2008): out./nov./dez.; 345-349
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
_version_ 1797042247575797760

Registros relacionados