Breast Microcalcifications Suspected of Malignancy
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/1505 |
Resumo: | Breast cancer is one of the leading causes of death by cancer among women in the Western world. The application of specific primary breast cancer prevention measures is limited for the general population. In the secondary prevention measures, efforts have been directed at early diagnosis. In this scenario, mammography is widely used as the most efficient means for breast cancer early detection. Mammary microcalcifications are often detected through screening mammography. Although most of them are benign, some may be cancerous. Thus, many biopsies originated from screening mammography programs aim to investigate microcalcifications suspected of malignancy. Therefore, it is necessary to appropriately qualify these microcalcifications, considering that the procedure to be followed is based on their precise analysis. In view of these facts, the present study has been based on the possibility of revising the characteristics of these microcalcifications, and contributing to improve the clinical practice as well as their diagnostic interpretation through mammography. The articles used to support this study have been researched in the online Medline, Lilacs and Pubmed databases, using keywords such as “mammography”, “breast neoplasms”, “calsinosis”. It has been concluded that in typically malignant microcalcifications, breast segments must be biopsied. In those suspected of malignancy, even after extensive study of their features, if they do not present enough signs of benignity in mammography, they must be investigated by a histopathological study. However, inconsistencies in microcalcification´s classification persist depending on morphology, suspicion level and final recommendations from BI-RADS™. Thus, more studies on the radiological-pathological relationship are important to improve the specificity of these variables. |
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Breast Microcalcifications Suspected of MalignancyMicrocalcificaciones Mamarias Sospechas de MalignidadMicrocalcificações Mamárias Suspeitas de MalignidadeMamografiaNeoplasias da MamaCalcinoseMammographyBreast NeoplasmsCalcinosisMamografíaNeoplasias de la MamaCalcicosisBreast cancer is one of the leading causes of death by cancer among women in the Western world. The application of specific primary breast cancer prevention measures is limited for the general population. In the secondary prevention measures, efforts have been directed at early diagnosis. In this scenario, mammography is widely used as the most efficient means for breast cancer early detection. Mammary microcalcifications are often detected through screening mammography. Although most of them are benign, some may be cancerous. Thus, many biopsies originated from screening mammography programs aim to investigate microcalcifications suspected of malignancy. Therefore, it is necessary to appropriately qualify these microcalcifications, considering that the procedure to be followed is based on their precise analysis. In view of these facts, the present study has been based on the possibility of revising the characteristics of these microcalcifications, and contributing to improve the clinical practice as well as their diagnostic interpretation through mammography. The articles used to support this study have been researched in the online Medline, Lilacs and Pubmed databases, using keywords such as “mammography”, “breast neoplasms”, “calsinosis”. It has been concluded that in typically malignant microcalcifications, breast segments must be biopsied. In those suspected of malignancy, even after extensive study of their features, if they do not present enough signs of benignity in mammography, they must be investigated by a histopathological study. However, inconsistencies in microcalcification´s classification persist depending on morphology, suspicion level and final recommendations from BI-RADS™. Thus, more studies on the radiological-pathological relationship are important to improve the specificity of these variables. El cáncer de mama recibe destaque en el mundo occidental porque es considerado la principal causa de muerte por cáncer en la población femenina. Medidas específicas para la prevención primaria del cáncer de mama poseen aplicación limitada en la población general. Con relación a la prevención secundaria, se han direccionados esfuerzos al diagnóstico precoz. En este escenario está la mamografía, el método más sensible en la detección precoz del cáncer de mama. Microcalcificaciones mamarias son detectadas con frecuencia en mamografías de rastreo y, aunque la mayoría sea benigna, algunas pueden representar cáncer. Así, muchas biopsias originadas del rastreo mamográfico se proponen investigar microcalcificaciones sospechas de malignidad. Por lo tanto, existe la necesidad de caracterizarlas de modo conveniente, ya que la conducta que debe ser seguida está basada en el análisis precisa de las mismas. Este trabajo fue desarrollado para revisar las características de esas microcalcificaciones y para que aportase con la mejoría de la interpretación diagnóstica y la conducta clínica frente al encuentro de las mismas mamografías. Los artículos fueron localizados por medio de la base de datos Medline, Lilacs y Pubmed a través del uso de descriptores “mamografía”, “neoplasia mamaria y “calcinose”. Se concluye que, en las calcificaciones malignas, los segmentos de la mama deben pasar por biopsia. En calcificaciones que presentasen sospecha de malignidad, aunque después de exhaustiva investigación no indicasen señales suficientes de molestia benigna, estas sospechas deben ser investigadas por medio del estudio anatomopatológico, sin embargo inconsistencias en la clasificación de las microcalcificaciones de acuerdo con la morfología, nivel de sospecha y la recomendación final del BI-RADS persisten, y otros estudios de relación radiológico-patológica serán importantes para la mejoría de la especificidad de estas variables. O câncer de mama ocupa lugar de destaque no mundo ocidental por ser a maior causa de morte por câncer na população feminina. Medidas específicas para a prevenção primária do câncer de mama são de aplicação limitada na população em geral. Na prevenção secundária, esforços têm sido direcionados ao diagnóstico precoce. Neste cenário, encontra-se a mamografia, considerada o método mais sensível para detectar precocemente o câncer de mama. Microcalcificações mamárias são frequentemente detectadas nas mamografias de rastreamento e, embora a maioria seja benigna, algumas podem representar câncer. Assim, muitas biópsias originadas do rastreamento mamográfico visam a investigar microcalcificações suspeitas de malignidade. Neste sentido, há necessidade de caracterizá-las adequadamente, já que a conduta a ser seguida baseia-se na análise precisa destas. Diante disso, desenvolveu-se este trabalho na perspectiva de revisar as características dessas microcalcificações, contribuindo para a melhora na interpretação diagnóstica e na conduta clínica frente ao encontro destas na mamografia. Os artigos que serviram de sustentação para o presente estudo foram localizados por meio das bases de dados Medline, Lilacs, e Pubmed, utilizando os descritores “mamografia”, “neoplasia mamaria” e “calcinose”. Concluiu-se que, nas calcificações tipicamente malignas, os segmentos da mama devem ser biopsiados. Naquelas suspeitas de malignidade, se mesmo após exaustivo estudo de suas características pela mamografia não apresentarem sinais suficientes que indiquem doença benigna, devem ser investigadas a partir de um estudo anatomopatológico. Entretanto, inconsistências na classificação das microcalcificações de acordo com a morfologia, o nível de suspeição e a recomendação final do BI-RADS™ persistem e mais estudos da relação radiológicopatológica serão importantes na melhora da especificidade dessas variáveis. INCA2010-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de literaturaapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/150510.32635/2176-9745.RBC.2010v56n2.1505Revista Brasileira de Cancerologia; Vol. 56 No. 2 (2010): Apr./May/June; 251-258Revista Brasileira de Cancerologia; Vol. 56 Núm. 2 (2010): abr./mayo/jun.; 251-258Revista Brasileira de Cancerologia; v. 56 n. 2 (2010): abr./maio/jun.; 251-2582176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/1505/905Martins, Letícia Athayde Linhares Barra, Alexandre de Almeida Lucena, Clécio Ênio Murta de info:eu-repo/semantics/openAccess2021-11-29T20:18:17Zoai:rbc.inca.gov.br:article/1505Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:18:17Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Breast Microcalcifications Suspected of Malignancy Microcalcificaciones Mamarias Sospechas de Malignidad Microcalcificações Mamárias Suspeitas de Malignidade |
title |
Breast Microcalcifications Suspected of Malignancy |
spellingShingle |
Breast Microcalcifications Suspected of Malignancy Martins, Letícia Athayde Linhares Mamografia Neoplasias da Mama Calcinose Mammography Breast Neoplasms Calcinosis Mamografía Neoplasias de la Mama Calcicosis |
title_short |
Breast Microcalcifications Suspected of Malignancy |
title_full |
Breast Microcalcifications Suspected of Malignancy |
title_fullStr |
Breast Microcalcifications Suspected of Malignancy |
title_full_unstemmed |
Breast Microcalcifications Suspected of Malignancy |
title_sort |
Breast Microcalcifications Suspected of Malignancy |
author |
Martins, Letícia Athayde Linhares |
author_facet |
Martins, Letícia Athayde Linhares Barra, Alexandre de Almeida Lucena, Clécio Ênio Murta de |
author_role |
author |
author2 |
Barra, Alexandre de Almeida Lucena, Clécio Ênio Murta de |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Martins, Letícia Athayde Linhares Barra, Alexandre de Almeida Lucena, Clécio Ênio Murta de |
dc.subject.por.fl_str_mv |
Mamografia Neoplasias da Mama Calcinose Mammography Breast Neoplasms Calcinosis Mamografía Neoplasias de la Mama Calcicosis |
topic |
Mamografia Neoplasias da Mama Calcinose Mammography Breast Neoplasms Calcinosis Mamografía Neoplasias de la Mama Calcicosis |
description |
Breast cancer is one of the leading causes of death by cancer among women in the Western world. The application of specific primary breast cancer prevention measures is limited for the general population. In the secondary prevention measures, efforts have been directed at early diagnosis. In this scenario, mammography is widely used as the most efficient means for breast cancer early detection. Mammary microcalcifications are often detected through screening mammography. Although most of them are benign, some may be cancerous. Thus, many biopsies originated from screening mammography programs aim to investigate microcalcifications suspected of malignancy. Therefore, it is necessary to appropriately qualify these microcalcifications, considering that the procedure to be followed is based on their precise analysis. In view of these facts, the present study has been based on the possibility of revising the characteristics of these microcalcifications, and contributing to improve the clinical practice as well as their diagnostic interpretation through mammography. The articles used to support this study have been researched in the online Medline, Lilacs and Pubmed databases, using keywords such as “mammography”, “breast neoplasms”, “calsinosis”. It has been concluded that in typically malignant microcalcifications, breast segments must be biopsied. In those suspected of malignancy, even after extensive study of their features, if they do not present enough signs of benignity in mammography, they must be investigated by a histopathological study. However, inconsistencies in microcalcification´s classification persist depending on morphology, suspicion level and final recommendations from BI-RADS™. Thus, more studies on the radiological-pathological relationship are important to improve the specificity of these variables. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-06-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Revisão de literatura |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/1505 10.32635/2176-9745.RBC.2010v56n2.1505 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/1505 |
identifier_str_mv |
10.32635/2176-9745.RBC.2010v56n2.1505 |
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por |
language |
por |
dc.relation.none.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/1505/905 |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
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INCA |
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INCA |
dc.source.none.fl_str_mv |
Revista Brasileira de Cancerologia; Vol. 56 No. 2 (2010): Apr./May/June; 251-258 Revista Brasileira de Cancerologia; Vol. 56 Núm. 2 (2010): abr./mayo/jun.; 251-258 Revista Brasileira de Cancerologia; v. 56 n. 2 (2010): abr./maio/jun.; 251-258 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
instname_str |
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
instacron_str |
INCA |
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INCA |
reponame_str |
Revista Brasileira de Cancerologia (Online) |
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Revista Brasileira de Cancerologia (Online) |
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Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
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rbc@inca.gov.br |
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