Tumores Germinativos Avançados - Tratamento com PVB

Detalhes bibliográficos
Autor(a) principal: Gomes Filho, Firmino de Azevedo
Data de Publicação: 2023
Outros Autores: Viola, Sandra Regina de Souza
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3200
Resumo: Thirteen patients with advanced germ-cell tumors were treated with PVB chemotherapy at Hospital de Oncologia - INA MPS - Rio de Janeiro, Brazil, during the last three years. One of these patients was not suitable for evaluation. In eight patients there was complete (66.7%) and in four partial remission (33.3%); in two cases relapses ocurred 12 and is 16 months after chemotherapy Three patients died afterpartial remission, two af ter failure of second choice therapeutic scheme (VP16 + CDDP), and one for discontinuing second choice scheme. Only one patient underwent two chemotherapy cicles. Mean follow-up was 21 months. The scheme was considered to be effectual and well tolerated. Remission indexes must be re-evaluated after longer periods of time.
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spelling Tumores Germinativos Avançados - Tratamento com PVBTumores GerminativosQuimioterapiaGerm-Cell TumorsChemotherapyThirteen patients with advanced germ-cell tumors were treated with PVB chemotherapy at Hospital de Oncologia - INA MPS - Rio de Janeiro, Brazil, during the last three years. One of these patients was not suitable for evaluation. In eight patients there was complete (66.7%) and in four partial remission (33.3%); in two cases relapses ocurred 12 and is 16 months after chemotherapy Three patients died afterpartial remission, two af ter failure of second choice therapeutic scheme (VP16 + CDDP), and one for discontinuing second choice scheme. Only one patient underwent two chemotherapy cicles. Mean follow-up was 21 months. The scheme was considered to be effectual and well tolerated. Remission indexes must be re-evaluated after longer periods of time.Treze pacientes portadores de tumores germinativos avançados foram tratados nos últimos três anos no Hospital de Oncologia --- INAMPS com esquema quimioterápico PVB. Destes, um paciente não é avaliável visto ter recebido dois ciclos incompletos e somente um tem apresentação extragonadal, sendo os demais primitivos do testículo. Oito pacientes apresentaram PC (66,7%) e quatro RP (33,3%). Duas recidivas ocorreram 12 e 16 meses após início da quimioterapia. Houve três óbitos, após RP dois por falha ao esquema de 2. linha (VP16 + CDDP) e um por evolução de doença após abandono de tratamento durante esquema de 2.' linha. Somente um paciente recebeu dois ciclos de quimioterapia que corresponde a tumor metacrônico. O período médio de acompanhamento é de 21 meses (oito a 39 meses). A média de ciclos é 3,8. O esquema é eficaz, a tolerabilidade muito boa, porém é necessário maior tempo para confirmarmos o percentual de remissão.INCA2023-08-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/320010.32635/2176-9745.RBC.1987v33n2.3200Revista Brasileira de Cancerologia; Vol. 33 No. 2 (1987): June; 159-166Revista Brasileira de Cancerologia; Vol. 33 Núm. 2 (1987): jun.; 159-166Revista Brasileira de Cancerologia; v. 33 n. 2 (1987): jun.; 159-1662176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/3200/2055https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGomes Filho, Firmino de AzevedoViola, Sandra Regina de Souza2023-08-04T18:35:50Zoai:rbc.inca.gov.br:article/3200Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-08-04T18:35:50Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Tumores Germinativos Avançados - Tratamento com PVB
title Tumores Germinativos Avançados - Tratamento com PVB
spellingShingle Tumores Germinativos Avançados - Tratamento com PVB
Gomes Filho, Firmino de Azevedo
Tumores Germinativos
Quimioterapia
Germ-Cell Tumors
Chemotherapy
title_short Tumores Germinativos Avançados - Tratamento com PVB
title_full Tumores Germinativos Avançados - Tratamento com PVB
title_fullStr Tumores Germinativos Avançados - Tratamento com PVB
title_full_unstemmed Tumores Germinativos Avançados - Tratamento com PVB
title_sort Tumores Germinativos Avançados - Tratamento com PVB
author Gomes Filho, Firmino de Azevedo
author_facet Gomes Filho, Firmino de Azevedo
Viola, Sandra Regina de Souza
author_role author
author2 Viola, Sandra Regina de Souza
author2_role author
dc.contributor.author.fl_str_mv Gomes Filho, Firmino de Azevedo
Viola, Sandra Regina de Souza
dc.subject.por.fl_str_mv Tumores Germinativos
Quimioterapia
Germ-Cell Tumors
Chemotherapy
topic Tumores Germinativos
Quimioterapia
Germ-Cell Tumors
Chemotherapy
description Thirteen patients with advanced germ-cell tumors were treated with PVB chemotherapy at Hospital de Oncologia - INA MPS - Rio de Janeiro, Brazil, during the last three years. One of these patients was not suitable for evaluation. In eight patients there was complete (66.7%) and in four partial remission (33.3%); in two cases relapses ocurred 12 and is 16 months after chemotherapy Three patients died afterpartial remission, two af ter failure of second choice therapeutic scheme (VP16 + CDDP), and one for discontinuing second choice scheme. Only one patient underwent two chemotherapy cicles. Mean follow-up was 21 months. The scheme was considered to be effectual and well tolerated. Remission indexes must be re-evaluated after longer periods of time.
publishDate 2023
dc.date.none.fl_str_mv 2023-08-04
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3200
10.32635/2176-9745.RBC.1987v33n2.3200
url https://rbc.inca.gov.br/index.php/revista/article/view/3200
identifier_str_mv 10.32635/2176-9745.RBC.1987v33n2.3200
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3200/2055
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 33 No. 2 (1987): June; 159-166
Revista Brasileira de Cancerologia; Vol. 33 Núm. 2 (1987): jun.; 159-166
Revista Brasileira de Cancerologia; v. 33 n. 2 (1987): jun.; 159-166
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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