Quimioterapia Adjuvante no Câncer da Mama

Detalhes bibliográficos
Autor(a) principal: Broecker Neto, Adalberto
Data de Publicação: 2023
Outros Autores: Lago, Sérgio, Radke, Rodolfo Coutinho, Costa, Ailzo José da, Hudson, Iara A.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3320
Resumo: A retrospectiva analysis of adjuvant chemotherapy in 95 patients with breast cancer was carried out. Patient stratification was made according to pathological status of axilary lymphonodes: group A patients with 1-3 positive nodes and group B patients with more than 3 positive lymphnodes. At sixty months the probability of survival was 86.1% for group A and 83% for group B (p=0.042) and, probability of disease free survival was 86.1%> in group A and 64.4% in group B (p<0.001). Forty nine patients were foilowed for at least 2 years and analysis after 24 months showed survival of 95.4% for group A and 85,1% for B (p=0.014) and, survival free of disease of 86.3% in group A and 66,6% in group B (p =0.415). Recurrence rate was 23.4% for patients receiving 85%> or more of programmed dose and 45% for patients whith lower doses. Local recurrences were identical for patients with or without radiotherapy. A comparison with the Milan study was made.
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spelling Quimioterapia Adjuvante no Câncer da MamaCâncer da MamaQuimioterapia AdjuvanteBreast CancerAdjuvant ChemotherapyA retrospectiva analysis of adjuvant chemotherapy in 95 patients with breast cancer was carried out. Patient stratification was made according to pathological status of axilary lymphonodes: group A patients with 1-3 positive nodes and group B patients with more than 3 positive lymphnodes. At sixty months the probability of survival was 86.1% for group A and 83% for group B (p=0.042) and, probability of disease free survival was 86.1%> in group A and 64.4% in group B (p<0.001). Forty nine patients were foilowed for at least 2 years and analysis after 24 months showed survival of 95.4% for group A and 85,1% for B (p=0.014) and, survival free of disease of 86.3% in group A and 66,6% in group B (p =0.415). Recurrence rate was 23.4% for patients receiving 85%> or more of programmed dose and 45% for patients whith lower doses. Local recurrences were identical for patients with or without radiotherapy. A comparison with the Milan study was made.Os autores fazem uma análise retrospectiva dos resultados do tratamento quimioterápico adjuvante em 95 pacientes com carcinoma da mama. As pacientes foram estratificadas pelo status patológico dos linfonodos axilares: grupo A com 1-3 linfonodos positivos e grupo B com mais de 3 linfonodos positivos. Aos 60 meses a probabilidade de sobrevida foi de 86,1% para o grupo A e de 83% para o B (p=0.042), a probabilidade de sobrevida sem doença foi de 86,1% no A e 64,4% no B (p<0.001). Em 49 pacientes acompanhadas por mais de 2 anos e avaliadas aos 24 meses a sobrevida foi de 95,4% no grupo A e de 85,1% no B (p=0.014), a sobrevida sem doença de 86,3% no A e de 66,6% no B (p=0.415). As pacientes que receberam 85% ou mais da dose prevista apresentaram 23,4% de recidivas e naquelas com doses menores foi de 45%. As recidivas locais foram semelhantes nas pacientes com e sem radioterapia. É feita uma comparação dos resultados obtidos com o estudo de Milão.INCA2023-08-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/332010.32635/2176-9745.RBC.1985v31n2.3320Revista Brasileira de Cancerologia; Vol. 31 No. 2 (1985): June; 119-124Revista Brasileira de Cancerologia; Vol. 31 Núm. 2 (1985): jun.; 119-124Revista Brasileira de Cancerologia; v. 31 n. 2 (1985): jun.; 119-1242176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/3320/2151https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBroecker Neto, AdalbertoLago, SérgioRadke, Rodolfo CoutinhoCosta, Ailzo José daHudson, Iara A.2023-08-08T18:23:18Zoai:rbc.inca.gov.br:article/3320Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-08-08T18:23:18Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Quimioterapia Adjuvante no Câncer da Mama
title Quimioterapia Adjuvante no Câncer da Mama
spellingShingle Quimioterapia Adjuvante no Câncer da Mama
Broecker Neto, Adalberto
Câncer da Mama
Quimioterapia Adjuvante
Breast Cancer
Adjuvant Chemotherapy
title_short Quimioterapia Adjuvante no Câncer da Mama
title_full Quimioterapia Adjuvante no Câncer da Mama
title_fullStr Quimioterapia Adjuvante no Câncer da Mama
title_full_unstemmed Quimioterapia Adjuvante no Câncer da Mama
title_sort Quimioterapia Adjuvante no Câncer da Mama
author Broecker Neto, Adalberto
author_facet Broecker Neto, Adalberto
Lago, Sérgio
Radke, Rodolfo Coutinho
Costa, Ailzo José da
Hudson, Iara A.
author_role author
author2 Lago, Sérgio
Radke, Rodolfo Coutinho
Costa, Ailzo José da
Hudson, Iara A.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Broecker Neto, Adalberto
Lago, Sérgio
Radke, Rodolfo Coutinho
Costa, Ailzo José da
Hudson, Iara A.
dc.subject.por.fl_str_mv Câncer da Mama
Quimioterapia Adjuvante
Breast Cancer
Adjuvant Chemotherapy
topic Câncer da Mama
Quimioterapia Adjuvante
Breast Cancer
Adjuvant Chemotherapy
description A retrospectiva analysis of adjuvant chemotherapy in 95 patients with breast cancer was carried out. Patient stratification was made according to pathological status of axilary lymphonodes: group A patients with 1-3 positive nodes and group B patients with more than 3 positive lymphnodes. At sixty months the probability of survival was 86.1% for group A and 83% for group B (p=0.042) and, probability of disease free survival was 86.1%> in group A and 64.4% in group B (p<0.001). Forty nine patients were foilowed for at least 2 years and analysis after 24 months showed survival of 95.4% for group A and 85,1% for B (p=0.014) and, survival free of disease of 86.3% in group A and 66,6% in group B (p =0.415). Recurrence rate was 23.4% for patients receiving 85%> or more of programmed dose and 45% for patients whith lower doses. Local recurrences were identical for patients with or without radiotherapy. A comparison with the Milan study was made.
publishDate 2023
dc.date.none.fl_str_mv 2023-08-08
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3320
10.32635/2176-9745.RBC.1985v31n2.3320
url https://rbc.inca.gov.br/index.php/revista/article/view/3320
identifier_str_mv 10.32635/2176-9745.RBC.1985v31n2.3320
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3320/2151
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 31 No. 2 (1985): June; 119-124
Revista Brasileira de Cancerologia; Vol. 31 Núm. 2 (1985): jun.; 119-124
Revista Brasileira de Cancerologia; v. 31 n. 2 (1985): jun.; 119-124
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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