Clinical and Epidemiological Analysis of 348 Cases of Prostate Adenocarcinoma Attended in a Cancer Care Center in Maranhão, Brazil

• Autor(a) principal: Furtado Ribeiro, Paulo Vitor
• Data de Publicação: 2013
• Outros Autores: Ribeiro da Silva, Raimunda, DallAgnol Torres dos Santos, Kamilla Karolinne, Furtado Loureiro, Flávia Helen, Furtado Amorim Franklin da Costa, Priscilla, Martel Uruçu, Lorena, Sousa Carlos, Anne Beatriz, Marçal Machado, Thalita, Mesquita Galvez Valdez, Erica Fernanda, Batista Amaral, Vinicius
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Brasileira de Cancerologia (Online)
• Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/968
• topic: Humanos; Masculino; Neoplasias da Próstata; Adenocarcinoma; Fatores Epidemiológicos; Biópsia; Humans; Male; Prostatic Neoplasms; Adenocarcinoma; Epidemiologic Factors; Biopsy; Humanos; Masculino; Neoplasias de la Próstata; Adenocarcinoma; Factores Epidemiológicos; Biópsia

Introduction: The prostate cancer is the main malignant neoplasm that occurs in men after nonmelanoma skin cancer. Clinical and epidemiological information on this pathology are scarce in Maranhão. Objectives: Analysis of clinical and epidemiological information of patients diagnosed with prostate cancer, in a Cancer Care Reference Center in Maranhão, between january 2008 and december 2009. Method: This is a retrospective and descriptive study in which 348 medical records of patients diagnosed with prostate cancer, at the Instituto Maranhense de Oncologia Aldenora Bello, were surveyed. The variables under consideration were: age, origin, occupation, initial prostate-specific antigen, Gleason score of the biopsy, Gleason score of the surgical specimen (in patients whose treatment included radical prostatectomy or transurethral resection of the prostate), and treatment. Results: The most affected age group was from 71 to 80 years old (39.7%). Most of patients were from Sao Luis – MA (64.1%) and did not have occupation (55.2%). Most of patients (32.8%) had prostate-specific antigen between 4.1 and 10 ng/ml. The Biopsy Gleason revealed moderate to weakly differentiated tumors in 48.5% of the cases. The predominant therapy was clinical treatment and/or subcapsular bilateral orquiectomy. Conclusion: This study demonstrated a significant association between the prostate-specific antigen and the age and Gleason Score, revealing in these patients a greater tendency to increase their levels the greater the age and higher histologic grading of tumors. A percentage of 36.5% of patients had both Biopsy and Surgery Specimen Gleason Scores equivalents.