Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/690 |
Resumo: | Introduction: This research is a descriptive bibliographical review. Objective: To describe the aspects related to the quadrivalent vaccine, found in both national and international scientific literature, as for its chemical description, indications, vaccination scheme, presentation and conservation, interaction with other vaccines, duration of protection, cross protection, safety, contraindications, immunogenicity, adverse reactions, efficacy and epidemiological and economics impact. Method: A search of studies was carried out in the Lilacs and Medline electronic data bases in the period between 2005 and 2009. Out of the 70 documents found, 35 were selected once they aggregated information about the several technical and practical aspects of the quadrivalent vaccine. With these documents in hands, an analytical reading was done and the papers organized by themes and their presentation. Results: Among the more relevant information it can be mentioned that it is indicated to women between 9 and 26 years old, before sexual initiation, being administered in three doses; it has confirmed efficacy against the serotypes present in it, being highly immunogenic and with protection guarantee for 5 years; it is safe, without any risk of infection with its administration and with mild to moderate local adverse effects. Conclusion: This study showed that there are important knowledge gaps about this vaccine that still need to be explained. |
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Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the PracticeVacuna contra el HPV y la Prevención de Cáncer del Cuello Uterino: Subsidios para la PrácticaVacina contra o HPV e a Prevenção do Câncer do Colo do Útero: Subsídios para a PráticaLiteratura de Revisão como AssuntoPrevenção de Câncer de Colo UterinoVacinas contra PapillomavirusReview Literature as TopicCervix Neoplasms PreventionPapillomavirus VaccinesLiteratura de Revisión como AsuntoPrevención de Cáncer de Cuello UterinoVacunas contra PapillomavirusIntroduction: This research is a descriptive bibliographical review. Objective: To describe the aspects related to the quadrivalent vaccine, found in both national and international scientific literature, as for its chemical description, indications, vaccination scheme, presentation and conservation, interaction with other vaccines, duration of protection, cross protection, safety, contraindications, immunogenicity, adverse reactions, efficacy and epidemiological and economics impact. Method: A search of studies was carried out in the Lilacs and Medline electronic data bases in the period between 2005 and 2009. Out of the 70 documents found, 35 were selected once they aggregated information about the several technical and practical aspects of the quadrivalent vaccine. With these documents in hands, an analytical reading was done and the papers organized by themes and their presentation. Results: Among the more relevant information it can be mentioned that it is indicated to women between 9 and 26 years old, before sexual initiation, being administered in three doses; it has confirmed efficacy against the serotypes present in it, being highly immunogenic and with protection guarantee for 5 years; it is safe, without any risk of infection with its administration and with mild to moderate local adverse effects. Conclusion: This study showed that there are important knowledge gaps about this vaccine that still need to be explained. Introducción: Esta investigación es una revisión de literatura, de abordaje descriptivo. Objetivo: Describir los aspectos relacionados a la vacuna cuadrivalente, encontrados en la literatura científica nacional e internacional, cuanto a su descripción química, indicaciones, esquema de vacunas, presentación y conservación, interacción con otras vacunas, duración de la protección, protección cruzada, seguridad, contraindicaciones, inmunogenicidad, reacciones adversas, eficacia e impacto epidemiológico y económico. Método: Se realizó un levantamiento de producciones en las bases de datos electrónicas Lilacs y Medline en el período de 2005 a 2009. De los 70 documentos encontrados, 35 fueron seleccionados pues agregaban informaciones sobre los diversos aspectos técnicos y prácticos de la vacuna cuadrivalente. De pose de esos documentos, se realizó la lectura analítica con organización por temas y su presentación. Resultados: Las informaciones más relevantes son las de que la vacuna está indicada para mujeres entre 9 y 26 años, antes de la iniciación sexual, y debe ministrarse en 3 dosis; se comprueba su eficacia contra los suero tipos existentes en ella, siendo altamente inmunogénica y con garantía de protección por 5 años; es segura, no existiendo riesgo de infección con su administración y con efectos adversos locales leves a moderados. Conclusión: El trabajo demostró que existen importantes vacíos del conocimiento sobre la vacuna que aún necesitan ser esclarecidos. Introdução: Trata-se de um estudo de revisão de literatura com abordagem descritiva. Objetivo: Descrever os aspectos relativos à vacina quadrivalente, encontrados na literatura científica nacional e internacional, quanto à sua descrição química, indicações, esquema vacinal, apresentação e conservação, interação com outras vacinas, duração da proteção, proteção cruzada, segurança, contraindicações, imunogenicidade, reações adversas, eficácia e impacto epidemiológico e econômico. Método: Foi realizado um levantamento de produções nas bases de dados eletrônicas Lilacs e Medline, no período entre 2005 e 2009. Dos 70 documentos encontrados, 35 foram selecionados, pois agregavam informações sobre os diversos aspectos técnicos e práticos da vacina quadrivalente. De posse desses documentos, foi realizada leitura analítica com organização por temas e sua apresentação. Resultados: Entre as informações mais relevantes, se pode citar que está indicada para mulheres entre 9 e 26 anos, antes da iniciação sexual, sendo administrada em três doses; possui eficácia comprovada contra os sorotipos nela presentes, sendo altamente imunogênica e com garantia de proteção por cinco anos; é segura, não havendo risco de infecção com a sua administração e com efeitos adversos locais leves a moderados. Conclusão: O trabalho demonstrou que há importantes lacunas do conhecimento sobre a vacina que ainda necessitam ser esclarecidas. INCA2011-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de literaturaapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/69010.32635/2176-9745.RBC.2011v57n1.690Revista Brasileira de Cancerologia; Vol. 57 No. 1 (2011): Jan./Feb./Mar.; 67-74Revista Brasileira de Cancerologia; Vol. 57 Núm. 1 (2011): ene./feb./mar.; 67-74Revista Brasileira de Cancerologia; v. 57 n. 1 (2011): jan./fev./mar.; 67-742176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/690/462Borsatto, Alessandra Zanei Vidal, Maria Luiza Bernardo Rocha, Renata Carla Nencetti Pereira info:eu-repo/semantics/openAccess2021-11-29T20:17:16Zoai:rbc.inca.gov.br:article/690Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:17:16Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice Vacuna contra el HPV y la Prevención de Cáncer del Cuello Uterino: Subsidios para la Práctica Vacina contra o HPV e a Prevenção do Câncer do Colo do Útero: Subsídios para a Prática |
title |
Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice |
spellingShingle |
Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice Borsatto, Alessandra Zanei Literatura de Revisão como Assunto Prevenção de Câncer de Colo Uterino Vacinas contra Papillomavirus Review Literature as Topic Cervix Neoplasms Prevention Papillomavirus Vaccines Literatura de Revisión como Asunto Prevención de Cáncer de Cuello Uterino Vacunas contra Papillomavirus |
title_short |
Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice |
title_full |
Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice |
title_fullStr |
Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice |
title_full_unstemmed |
Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice |
title_sort |
Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice |
author |
Borsatto, Alessandra Zanei |
author_facet |
Borsatto, Alessandra Zanei Vidal, Maria Luiza Bernardo Rocha, Renata Carla Nencetti Pereira |
author_role |
author |
author2 |
Vidal, Maria Luiza Bernardo Rocha, Renata Carla Nencetti Pereira |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Borsatto, Alessandra Zanei Vidal, Maria Luiza Bernardo Rocha, Renata Carla Nencetti Pereira |
dc.subject.por.fl_str_mv |
Literatura de Revisão como Assunto Prevenção de Câncer de Colo Uterino Vacinas contra Papillomavirus Review Literature as Topic Cervix Neoplasms Prevention Papillomavirus Vaccines Literatura de Revisión como Asunto Prevención de Cáncer de Cuello Uterino Vacunas contra Papillomavirus |
topic |
Literatura de Revisão como Assunto Prevenção de Câncer de Colo Uterino Vacinas contra Papillomavirus Review Literature as Topic Cervix Neoplasms Prevention Papillomavirus Vaccines Literatura de Revisión como Asunto Prevención de Cáncer de Cuello Uterino Vacunas contra Papillomavirus |
description |
Introduction: This research is a descriptive bibliographical review. Objective: To describe the aspects related to the quadrivalent vaccine, found in both national and international scientific literature, as for its chemical description, indications, vaccination scheme, presentation and conservation, interaction with other vaccines, duration of protection, cross protection, safety, contraindications, immunogenicity, adverse reactions, efficacy and epidemiological and economics impact. Method: A search of studies was carried out in the Lilacs and Medline electronic data bases in the period between 2005 and 2009. Out of the 70 documents found, 35 were selected once they aggregated information about the several technical and practical aspects of the quadrivalent vaccine. With these documents in hands, an analytical reading was done and the papers organized by themes and their presentation. Results: Among the more relevant information it can be mentioned that it is indicated to women between 9 and 26 years old, before sexual initiation, being administered in three doses; it has confirmed efficacy against the serotypes present in it, being highly immunogenic and with protection guarantee for 5 years; it is safe, without any risk of infection with its administration and with mild to moderate local adverse effects. Conclusion: This study showed that there are important knowledge gaps about this vaccine that still need to be explained. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-03-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Revisão de literatura |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/690 10.32635/2176-9745.RBC.2011v57n1.690 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/690 |
identifier_str_mv |
10.32635/2176-9745.RBC.2011v57n1.690 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/690/462 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
INCA |
publisher.none.fl_str_mv |
INCA |
dc.source.none.fl_str_mv |
Revista Brasileira de Cancerologia; Vol. 57 No. 1 (2011): Jan./Feb./Mar.; 67-74 Revista Brasileira de Cancerologia; Vol. 57 Núm. 1 (2011): ene./feb./mar.; 67-74 Revista Brasileira de Cancerologia; v. 57 n. 1 (2011): jan./fev./mar.; 67-74 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
instname_str |
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
instacron_str |
INCA |
institution |
INCA |
reponame_str |
Revista Brasileira de Cancerologia (Online) |
collection |
Revista Brasileira de Cancerologia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
repository.mail.fl_str_mv |
rbc@inca.gov.br |
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