Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice

Detalhes bibliográficos
Autor(a) principal: Borsatto, Alessandra Zanei
Data de Publicação: 2011
Outros Autores: Vidal, Maria Luiza Bernardo, Rocha, Renata Carla Nencetti Pereira
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/690
Resumo: Introduction: This research is a descriptive bibliographical review. Objective: To describe the aspects related to the quadrivalent vaccine, found in both national and international scientific literature, as for its chemical description, indications, vaccination scheme, presentation and conservation, interaction with other vaccines, duration of protection, cross protection, safety, contraindications, immunogenicity, adverse reactions, efficacy and epidemiological and economics impact. Method: A search of studies was carried out in the Lilacs and Medline electronic data bases in the period between 2005 and 2009. Out of the 70 documents found, 35 were selected once they aggregated information about the several technical and practical aspects of the quadrivalent vaccine. With these documents in hands, an analytical reading was done and the papers organized by themes and their presentation. Results: Among the more relevant information it can be mentioned that it is indicated to women between 9 and 26 years old, before sexual initiation, being administered in three doses; it has confirmed efficacy against the serotypes present in it, being highly immunogenic and with protection guarantee for 5 years; it is safe, without any risk of infection with its administration and with mild to moderate local adverse effects. Conclusion: This study showed that there are important knowledge gaps about this vaccine that still need to be explained.  
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spelling Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the PracticeVacuna contra el HPV y la Prevención de Cáncer del Cuello Uterino: Subsidios para la PrácticaVacina contra o HPV e a Prevenção do Câncer do Colo do Útero: Subsídios para a PráticaLiteratura de Revisão como AssuntoPrevenção de Câncer de Colo UterinoVacinas contra PapillomavirusReview Literature as TopicCervix Neoplasms PreventionPapillomavirus VaccinesLiteratura de Revisión como AsuntoPrevención de Cáncer de Cuello UterinoVacunas contra PapillomavirusIntroduction: This research is a descriptive bibliographical review. Objective: To describe the aspects related to the quadrivalent vaccine, found in both national and international scientific literature, as for its chemical description, indications, vaccination scheme, presentation and conservation, interaction with other vaccines, duration of protection, cross protection, safety, contraindications, immunogenicity, adverse reactions, efficacy and epidemiological and economics impact. Method: A search of studies was carried out in the Lilacs and Medline electronic data bases in the period between 2005 and 2009. Out of the 70 documents found, 35 were selected once they aggregated information about the several technical and practical aspects of the quadrivalent vaccine. With these documents in hands, an analytical reading was done and the papers organized by themes and their presentation. Results: Among the more relevant information it can be mentioned that it is indicated to women between 9 and 26 years old, before sexual initiation, being administered in three doses; it has confirmed efficacy against the serotypes present in it, being highly immunogenic and with protection guarantee for 5 years; it is safe, without any risk of infection with its administration and with mild to moderate local adverse effects. Conclusion: This study showed that there are important knowledge gaps about this vaccine that still need to be explained.  Introducción: Esta investigación es una revisión de literatura, de abordaje descriptivo. Objetivo: Describir los aspectos relacionados a la vacuna cuadrivalente, encontrados en la literatura científica nacional e internacional, cuanto a su descripción química, indicaciones, esquema de vacunas, presentación y conservación, interacción con otras vacunas, duración de la protección, protección cruzada, seguridad, contraindicaciones, inmunogenicidad, reacciones adversas, eficacia e impacto epidemiológico y económico. Método: Se realizó un levantamiento de producciones en las bases de datos electrónicas Lilacs y Medline en el período de 2005 a 2009. De los 70 documentos encontrados, 35 fueron seleccionados pues agregaban informaciones sobre los diversos aspectos técnicos y prácticos de la vacuna cuadrivalente. De pose de esos documentos, se realizó la lectura analítica con organización por temas y su presentación. Resultados: Las informaciones más relevantes son las de que la vacuna está indicada para mujeres entre 9 y 26 años, antes de la iniciación sexual, y debe ministrarse en 3 dosis; se comprueba su eficacia contra los suero tipos existentes en ella, siendo altamente inmunogénica y con garantía de protección por 5 años; es segura, no existiendo riesgo de infección con su administración y con efectos adversos locales leves a moderados. Conclusión: El trabajo demostró que existen importantes vacíos del conocimiento sobre la vacuna que aún necesitan ser esclarecidos.  Introdução: Trata-se de um estudo de revisão de literatura com abordagem descritiva. Objetivo: Descrever os aspectos relativos à vacina quadrivalente, encontrados na literatura científica nacional e internacional, quanto à sua descrição química, indicações, esquema vacinal, apresentação e conservação, interação com outras vacinas, duração da proteção, proteção cruzada, segurança, contraindicações, imunogenicidade, reações adversas, eficácia e impacto epidemiológico e econômico. Método: Foi realizado um levantamento de produções nas bases de dados eletrônicas Lilacs e Medline, no período entre 2005 e 2009. Dos 70 documentos encontrados, 35 foram selecionados, pois agregavam informações sobre os diversos aspectos técnicos e práticos da vacina quadrivalente. De posse desses documentos, foi realizada leitura analítica com organização por temas e sua apresentação. Resultados: Entre as informações mais relevantes, se pode citar que está indicada para mulheres entre 9 e 26 anos, antes da iniciação sexual, sendo administrada em três doses; possui eficácia comprovada contra os sorotipos nela presentes, sendo altamente imunogênica e com garantia de proteção por cinco anos; é segura, não havendo risco de infecção com a sua administração e com efeitos adversos locais leves a moderados. Conclusão: O trabalho demonstrou que há importantes lacunas do conhecimento sobre a vacina que ainda necessitam ser esclarecidas.  INCA2011-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de literaturaapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/69010.32635/2176-9745.RBC.2011v57n1.690Revista Brasileira de Cancerologia; Vol. 57 No. 1 (2011): Jan./Feb./Mar.; 67-74Revista Brasileira de Cancerologia; Vol. 57 Núm. 1 (2011): ene./feb./mar.; 67-74Revista Brasileira de Cancerologia; v. 57 n. 1 (2011): jan./fev./mar.; 67-742176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/690/462Borsatto, Alessandra Zanei Vidal, Maria Luiza Bernardo Rocha, Renata Carla Nencetti Pereira info:eu-repo/semantics/openAccess2021-11-29T20:17:16Zoai:rbc.inca.gov.br:article/690Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:17:16Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice
Vacuna contra el HPV y la Prevención de Cáncer del Cuello Uterino: Subsidios para la Práctica
Vacina contra o HPV e a Prevenção do Câncer do Colo do Útero: Subsídios para a Prática
title Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice
spellingShingle Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice
Borsatto, Alessandra Zanei
Literatura de Revisão como Assunto
Prevenção de Câncer de Colo Uterino
Vacinas contra Papillomavirus
Review Literature as Topic
Cervix Neoplasms Prevention
Papillomavirus Vaccines
Literatura de Revisión como Asunto
Prevención de Cáncer de Cuello Uterino
Vacunas contra Papillomavirus
title_short Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice
title_full Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice
title_fullStr Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice
title_full_unstemmed Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice
title_sort Subsídios para a Prática HPV Vaccine and the Prevention of Cervical Uterus Cancer: Subsidies to the Practice
author Borsatto, Alessandra Zanei
author_facet Borsatto, Alessandra Zanei
Vidal, Maria Luiza Bernardo
Rocha, Renata Carla Nencetti Pereira
author_role author
author2 Vidal, Maria Luiza Bernardo
Rocha, Renata Carla Nencetti Pereira
author2_role author
author
dc.contributor.author.fl_str_mv Borsatto, Alessandra Zanei
Vidal, Maria Luiza Bernardo
Rocha, Renata Carla Nencetti Pereira
dc.subject.por.fl_str_mv Literatura de Revisão como Assunto
Prevenção de Câncer de Colo Uterino
Vacinas contra Papillomavirus
Review Literature as Topic
Cervix Neoplasms Prevention
Papillomavirus Vaccines
Literatura de Revisión como Asunto
Prevención de Cáncer de Cuello Uterino
Vacunas contra Papillomavirus
topic Literatura de Revisão como Assunto
Prevenção de Câncer de Colo Uterino
Vacinas contra Papillomavirus
Review Literature as Topic
Cervix Neoplasms Prevention
Papillomavirus Vaccines
Literatura de Revisión como Asunto
Prevención de Cáncer de Cuello Uterino
Vacunas contra Papillomavirus
description Introduction: This research is a descriptive bibliographical review. Objective: To describe the aspects related to the quadrivalent vaccine, found in both national and international scientific literature, as for its chemical description, indications, vaccination scheme, presentation and conservation, interaction with other vaccines, duration of protection, cross protection, safety, contraindications, immunogenicity, adverse reactions, efficacy and epidemiological and economics impact. Method: A search of studies was carried out in the Lilacs and Medline electronic data bases in the period between 2005 and 2009. Out of the 70 documents found, 35 were selected once they aggregated information about the several technical and practical aspects of the quadrivalent vaccine. With these documents in hands, an analytical reading was done and the papers organized by themes and their presentation. Results: Among the more relevant information it can be mentioned that it is indicated to women between 9 and 26 years old, before sexual initiation, being administered in three doses; it has confirmed efficacy against the serotypes present in it, being highly immunogenic and with protection guarantee for 5 years; it is safe, without any risk of infection with its administration and with mild to moderate local adverse effects. Conclusion: This study showed that there are important knowledge gaps about this vaccine that still need to be explained.  
publishDate 2011
dc.date.none.fl_str_mv 2011-03-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Revisão de literatura
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status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/690
10.32635/2176-9745.RBC.2011v57n1.690
url https://rbc.inca.gov.br/index.php/revista/article/view/690
identifier_str_mv 10.32635/2176-9745.RBC.2011v57n1.690
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dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/690/462
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dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 57 No. 1 (2011): Jan./Feb./Mar.; 67-74
Revista Brasileira de Cancerologia; Vol. 57 Núm. 1 (2011): ene./feb./mar.; 67-74
Revista Brasileira de Cancerologia; v. 57 n. 1 (2011): jan./fev./mar.; 67-74
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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