Axc Rat Lymphoma in Tissue Culture; Electron Microscopic Observations

Detalhes bibliográficos
Autor(a) principal: Queiroz, Aristides Cheto de
Data de Publicação: 2023
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3881
Resumo: A previous publication documented a sarcomatous transformation observed in a cell line derived from a rat lymphoma growing in monolayer culture. (9) The morphological and cytogenetic changes found, suggested the presence of virus and the differentiation of the malignant lymphoblasts toward malignant histiocytes in culture. The present paper describes, under the electron microscope the structural features of the original tumor, of the cells growing in culture and of the derived sarcoma. This study will serve to complement the prior observations.
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spelling Axc Rat Lymphoma in Tissue Culture; Electron Microscopic ObservationsRatos Endogâmicos ACILinfomaTécnicas de Cultura de TecidosRats, Inbred ACILymphomaTissue Culture TechniquesRatas Endogámicas ACILinfomaTécnicas de Cultivo de TejidosA previous publication documented a sarcomatous transformation observed in a cell line derived from a rat lymphoma growing in monolayer culture. (9) The morphological and cytogenetic changes found, suggested the presence of virus and the differentiation of the malignant lymphoblasts toward malignant histiocytes in culture. The present paper describes, under the electron microscope the structural features of the original tumor, of the cells growing in culture and of the derived sarcoma. This study will serve to complement the prior observations.Neste trabalho foram estudados os aspectos ultra-estruturais de um linfoma obtido espontaneamente em ratos da cepa AxC. As células derivadas desse tumor, crescendo em cultura de tecido, bem como o sarcoma obtido da inoculação dessas células em animais da mesma cepa, foram também examinadas ao microscópio eletrônico. As células do tumor original mostraram características descritas para linfoblastos. Na cultura, as células que mostraram aspecto morfológico diferente do das células do tumor original apresentaram pontos de junção entre as membranas celulares semelhantes ao que se vê entre as células epiteliais. O significado deste achado é discutido. A estrutura das células do sarcoma mostrou características de células fagocitárias, reforçando a natureza histiocítica do tumor, o que já havia sido sugerido no trabalho anterior. A pesquisa de vírus neste estudo foi negativa.INCA2023-08-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/388110.32635/2176-9745.RBC.1975v25n2.3881Revista Brasileira de Cancerologia; Vol. 25 No. 2 (1975): Jan./Feb.; 53-57Revista Brasileira de Cancerologia; Vol. 25 Núm. 2 (1975): ene./feb.; 53-57Revista Brasileira de Cancerologia; v. 25 n. 2 (1975): jan./fev.; 53-572176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAenghttps://rbc.inca.gov.br/index.php/revista/article/view/3881/2713https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessQueiroz, Aristides Cheto de2023-08-17T21:05:41Zoai:rbc.inca.gov.br:article/3881Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-08-17T21:05:41Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Axc Rat Lymphoma in Tissue Culture; Electron Microscopic Observations
title Axc Rat Lymphoma in Tissue Culture; Electron Microscopic Observations
spellingShingle Axc Rat Lymphoma in Tissue Culture; Electron Microscopic Observations
Queiroz, Aristides Cheto de
Ratos Endogâmicos ACI
Linfoma
Técnicas de Cultura de Tecidos
Rats, Inbred ACI
Lymphoma
Tissue Culture Techniques
Ratas Endogámicas ACI
Linfoma
Técnicas de Cultivo de Tejidos
title_short Axc Rat Lymphoma in Tissue Culture; Electron Microscopic Observations
title_full Axc Rat Lymphoma in Tissue Culture; Electron Microscopic Observations
title_fullStr Axc Rat Lymphoma in Tissue Culture; Electron Microscopic Observations
title_full_unstemmed Axc Rat Lymphoma in Tissue Culture; Electron Microscopic Observations
title_sort Axc Rat Lymphoma in Tissue Culture; Electron Microscopic Observations
author Queiroz, Aristides Cheto de
author_facet Queiroz, Aristides Cheto de
author_role author
dc.contributor.author.fl_str_mv Queiroz, Aristides Cheto de
dc.subject.por.fl_str_mv Ratos Endogâmicos ACI
Linfoma
Técnicas de Cultura de Tecidos
Rats, Inbred ACI
Lymphoma
Tissue Culture Techniques
Ratas Endogámicas ACI
Linfoma
Técnicas de Cultivo de Tejidos
topic Ratos Endogâmicos ACI
Linfoma
Técnicas de Cultura de Tecidos
Rats, Inbred ACI
Lymphoma
Tissue Culture Techniques
Ratas Endogámicas ACI
Linfoma
Técnicas de Cultivo de Tejidos
description A previous publication documented a sarcomatous transformation observed in a cell line derived from a rat lymphoma growing in monolayer culture. (9) The morphological and cytogenetic changes found, suggested the presence of virus and the differentiation of the malignant lymphoblasts toward malignant histiocytes in culture. The present paper describes, under the electron microscope the structural features of the original tumor, of the cells growing in culture and of the derived sarcoma. This study will serve to complement the prior observations.
publishDate 2023
dc.date.none.fl_str_mv 2023-08-17
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3881
10.32635/2176-9745.RBC.1975v25n2.3881
url https://rbc.inca.gov.br/index.php/revista/article/view/3881
identifier_str_mv 10.32635/2176-9745.RBC.1975v25n2.3881
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3881/2713
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 25 No. 2 (1975): Jan./Feb.; 53-57
Revista Brasileira de Cancerologia; Vol. 25 Núm. 2 (1975): ene./feb.; 53-57
Revista Brasileira de Cancerologia; v. 25 n. 2 (1975): jan./fev.; 53-57
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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