Oral Cancer and Candida

Detalhes bibliográficos
Autor(a) principal: Kignel, Sérgio
Data de Publicação: 2000
Outros Autores: Birman, Esther Goldenberg
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
DOI: 10.32635/2176-9745.RBC.2000v46n3.2438
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/2438
Resumo: Having in mind the role of fungi in relation to oral cancer, were evaluated 33 patients with oral cancer, diagnosed as squamous cell carcinoma, classified as T1N0M0 or T2N0M0 . The patients were habitual drinkers and smokers, not submitted previously to any treatment related to fungi or to the present neoplasm. Samples from the oral mucosa were collected and cultured in order to identify the present yeast. Clinical aspects were also evaluated either related to the neoplasm or to candidosis. A predominance of ulcerative cancer lesions were observed, being mainly localised on the floor of the mouth. Positive cultures were represented basically by C. albicans and also six other different species isolated or in association. Pseudo-membranous or erythematous candidosis were not observed. The specificity of the identified fungi, the conditions of colonisation of these patients either related to the development of the neoplasm, immune condition or different treatments related can induce their development, leading us to attention and care for these patients in relation to the mycological aspects observed.  
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spelling Oral Cancer and CandidaAspectos Fúngicos do Câncer BucalC. AlbicansNeoplasias BucaisCarcinoma EpidermóideBoca, FumantesCandida AlbicansFungi, Mouth NeoplasmsSquamous Cell CarcinomaSmokersHaving in mind the role of fungi in relation to oral cancer, were evaluated 33 patients with oral cancer, diagnosed as squamous cell carcinoma, classified as T1N0M0 or T2N0M0 . The patients were habitual drinkers and smokers, not submitted previously to any treatment related to fungi or to the present neoplasm. Samples from the oral mucosa were collected and cultured in order to identify the present yeast. Clinical aspects were also evaluated either related to the neoplasm or to candidosis. A predominance of ulcerative cancer lesions were observed, being mainly localised on the floor of the mouth. Positive cultures were represented basically by C. albicans and also six other different species isolated or in association. Pseudo-membranous or erythematous candidosis were not observed. The specificity of the identified fungi, the conditions of colonisation of these patients either related to the development of the neoplasm, immune condition or different treatments related can induce their development, leading us to attention and care for these patients in relation to the mycological aspects observed.  Tendo em mente os aspectos relacionados à presença de fungos e seu discutível papel em relação ao câncer bucal, avaliou-se 33 pacientes fumantes e etilistas crônicos, livres de qualquer tratamento antineoplásico ou antifúngico, com carcinoma epidermóide da mucosa bucal em estádio T1N0M0 ou T2N0M0. Após exame clínico local, foram realizadas coleta, cultura e identificação de fungos, observando-se, no grupo em estudo, predominância do sexo masculino e presença de lesões do tipo ulcerativo, localizadas, principalmente, no assoalho bucal e, em menor número, em outras áreas. Dos 42 pacientes, 4% eram portadores de fungos, destacando-se a presença de Candida albicans, além de outras seis espécies, ora associadas ora isoladas. Lesões clínicas sugestivas de candidíase pseudo-membranosa ou eritematosa não foram detectadas. Mesmo frente à ausência de manifestações clínicas de candidíase, é necessário lembrar que mudanças podem ocorrer em face do desenvolvimento de neoplasia, tratamento instituído ou mesmo condições imunológicas, facilitando a seletividade, colonização e desenvolvimento patogênico dos fungos, merecendo estes pacientes atenção e cuidados frente aos aspectos micológicos envolvidos.INCA2000-09-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/243810.32635/2176-9745.RBC.2000v46n3.2438Revista Brasileira de Cancerologia; Vol. 46 No. 3 (2000): July/Aug./Sept.; 279-82Revista Brasileira de Cancerologia; Vol. 46 Núm. 3 (2000): jul./ago./sept.; 279-82Revista Brasileira de Cancerologia; v. 46 n. 3 (2000): jul./ago./set.; 279-822176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/2438/1517Kignel, Sérgio Birman, Esther Goldenberg info:eu-repo/semantics/openAccess2021-11-29T20:43:43Zoai:rbc.inca.gov.br:article/2438Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:43:43Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Oral Cancer and Candida
Aspectos Fúngicos do Câncer Bucal
title Oral Cancer and Candida
spellingShingle Oral Cancer and Candida
Oral Cancer and Candida
Kignel, Sérgio
C. Albicans
Neoplasias Bucais
Carcinoma Epidermóide
Boca, Fumantes
Candida Albicans
Fungi, Mouth Neoplasms
Squamous Cell Carcinoma
Smokers
Kignel, Sérgio
C. Albicans
Neoplasias Bucais
Carcinoma Epidermóide
Boca, Fumantes
Candida Albicans
Fungi, Mouth Neoplasms
Squamous Cell Carcinoma
Smokers
title_short Oral Cancer and Candida
title_full Oral Cancer and Candida
title_fullStr Oral Cancer and Candida
Oral Cancer and Candida
title_full_unstemmed Oral Cancer and Candida
Oral Cancer and Candida
title_sort Oral Cancer and Candida
author Kignel, Sérgio
author_facet Kignel, Sérgio
Kignel, Sérgio
Birman, Esther Goldenberg
Birman, Esther Goldenberg
author_role author
author2 Birman, Esther Goldenberg
author2_role author
dc.contributor.author.fl_str_mv Kignel, Sérgio
Birman, Esther Goldenberg
dc.subject.por.fl_str_mv C. Albicans
Neoplasias Bucais
Carcinoma Epidermóide
Boca, Fumantes
Candida Albicans
Fungi, Mouth Neoplasms
Squamous Cell Carcinoma
Smokers
topic C. Albicans
Neoplasias Bucais
Carcinoma Epidermóide
Boca, Fumantes
Candida Albicans
Fungi, Mouth Neoplasms
Squamous Cell Carcinoma
Smokers
description Having in mind the role of fungi in relation to oral cancer, were evaluated 33 patients with oral cancer, diagnosed as squamous cell carcinoma, classified as T1N0M0 or T2N0M0 . The patients were habitual drinkers and smokers, not submitted previously to any treatment related to fungi or to the present neoplasm. Samples from the oral mucosa were collected and cultured in order to identify the present yeast. Clinical aspects were also evaluated either related to the neoplasm or to candidosis. A predominance of ulcerative cancer lesions were observed, being mainly localised on the floor of the mouth. Positive cultures were represented basically by C. albicans and also six other different species isolated or in association. Pseudo-membranous or erythematous candidosis were not observed. The specificity of the identified fungi, the conditions of colonisation of these patients either related to the development of the neoplasm, immune condition or different treatments related can induce their development, leading us to attention and care for these patients in relation to the mycological aspects observed.  
publishDate 2000
dc.date.none.fl_str_mv 2000-09-29
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/2438
10.32635/2176-9745.RBC.2000v46n3.2438
url https://rbc.inca.gov.br/index.php/revista/article/view/2438
identifier_str_mv 10.32635/2176-9745.RBC.2000v46n3.2438
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/2438/1517
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 46 No. 3 (2000): July/Aug./Sept.; 279-82
Revista Brasileira de Cancerologia; Vol. 46 Núm. 3 (2000): jul./ago./sept.; 279-82
Revista Brasileira de Cancerologia; v. 46 n. 3 (2000): jul./ago./set.; 279-82
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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dc.identifier.doi.none.fl_str_mv 10.32635/2176-9745.RBC.2000v46n3.2438