Oral Cancer and Candida
Autor(a) principal: | |
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Data de Publicação: | 2000 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
DOI: | 10.32635/2176-9745.RBC.2000v46n3.2438 |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/2438 |
Resumo: | Having in mind the role of fungi in relation to oral cancer, were evaluated 33 patients with oral cancer, diagnosed as squamous cell carcinoma, classified as T1N0M0 or T2N0M0 . The patients were habitual drinkers and smokers, not submitted previously to any treatment related to fungi or to the present neoplasm. Samples from the oral mucosa were collected and cultured in order to identify the present yeast. Clinical aspects were also evaluated either related to the neoplasm or to candidosis. A predominance of ulcerative cancer lesions were observed, being mainly localised on the floor of the mouth. Positive cultures were represented basically by C. albicans and also six other different species isolated or in association. Pseudo-membranous or erythematous candidosis were not observed. The specificity of the identified fungi, the conditions of colonisation of these patients either related to the development of the neoplasm, immune condition or different treatments related can induce their development, leading us to attention and care for these patients in relation to the mycological aspects observed. |
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Oral Cancer and CandidaAspectos Fúngicos do Câncer BucalC. AlbicansNeoplasias BucaisCarcinoma EpidermóideBoca, FumantesCandida AlbicansFungi, Mouth NeoplasmsSquamous Cell CarcinomaSmokersHaving in mind the role of fungi in relation to oral cancer, were evaluated 33 patients with oral cancer, diagnosed as squamous cell carcinoma, classified as T1N0M0 or T2N0M0 . The patients were habitual drinkers and smokers, not submitted previously to any treatment related to fungi or to the present neoplasm. Samples from the oral mucosa were collected and cultured in order to identify the present yeast. Clinical aspects were also evaluated either related to the neoplasm or to candidosis. A predominance of ulcerative cancer lesions were observed, being mainly localised on the floor of the mouth. Positive cultures were represented basically by C. albicans and also six other different species isolated or in association. Pseudo-membranous or erythematous candidosis were not observed. The specificity of the identified fungi, the conditions of colonisation of these patients either related to the development of the neoplasm, immune condition or different treatments related can induce their development, leading us to attention and care for these patients in relation to the mycological aspects observed. Tendo em mente os aspectos relacionados à presença de fungos e seu discutível papel em relação ao câncer bucal, avaliou-se 33 pacientes fumantes e etilistas crônicos, livres de qualquer tratamento antineoplásico ou antifúngico, com carcinoma epidermóide da mucosa bucal em estádio T1N0M0 ou T2N0M0. Após exame clínico local, foram realizadas coleta, cultura e identificação de fungos, observando-se, no grupo em estudo, predominância do sexo masculino e presença de lesões do tipo ulcerativo, localizadas, principalmente, no assoalho bucal e, em menor número, em outras áreas. Dos 42 pacientes, 4% eram portadores de fungos, destacando-se a presença de Candida albicans, além de outras seis espécies, ora associadas ora isoladas. Lesões clínicas sugestivas de candidíase pseudo-membranosa ou eritematosa não foram detectadas. Mesmo frente à ausência de manifestações clínicas de candidíase, é necessário lembrar que mudanças podem ocorrer em face do desenvolvimento de neoplasia, tratamento instituído ou mesmo condições imunológicas, facilitando a seletividade, colonização e desenvolvimento patogênico dos fungos, merecendo estes pacientes atenção e cuidados frente aos aspectos micológicos envolvidos.INCA2000-09-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/243810.32635/2176-9745.RBC.2000v46n3.2438Revista Brasileira de Cancerologia; Vol. 46 No. 3 (2000): July/Aug./Sept.; 279-82Revista Brasileira de Cancerologia; Vol. 46 Núm. 3 (2000): jul./ago./sept.; 279-82Revista Brasileira de Cancerologia; v. 46 n. 3 (2000): jul./ago./set.; 279-822176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/2438/1517Kignel, Sérgio Birman, Esther Goldenberg info:eu-repo/semantics/openAccess2021-11-29T20:43:43Zoai:rbc.inca.gov.br:article/2438Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:43:43Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Oral Cancer and Candida Aspectos Fúngicos do Câncer Bucal |
title |
Oral Cancer and Candida |
spellingShingle |
Oral Cancer and Candida Oral Cancer and Candida Kignel, Sérgio C. Albicans Neoplasias Bucais Carcinoma Epidermóide Boca, Fumantes Candida Albicans Fungi, Mouth Neoplasms Squamous Cell Carcinoma Smokers Kignel, Sérgio C. Albicans Neoplasias Bucais Carcinoma Epidermóide Boca, Fumantes Candida Albicans Fungi, Mouth Neoplasms Squamous Cell Carcinoma Smokers |
title_short |
Oral Cancer and Candida |
title_full |
Oral Cancer and Candida |
title_fullStr |
Oral Cancer and Candida Oral Cancer and Candida |
title_full_unstemmed |
Oral Cancer and Candida Oral Cancer and Candida |
title_sort |
Oral Cancer and Candida |
author |
Kignel, Sérgio |
author_facet |
Kignel, Sérgio Kignel, Sérgio Birman, Esther Goldenberg Birman, Esther Goldenberg |
author_role |
author |
author2 |
Birman, Esther Goldenberg |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Kignel, Sérgio Birman, Esther Goldenberg |
dc.subject.por.fl_str_mv |
C. Albicans Neoplasias Bucais Carcinoma Epidermóide Boca, Fumantes Candida Albicans Fungi, Mouth Neoplasms Squamous Cell Carcinoma Smokers |
topic |
C. Albicans Neoplasias Bucais Carcinoma Epidermóide Boca, Fumantes Candida Albicans Fungi, Mouth Neoplasms Squamous Cell Carcinoma Smokers |
description |
Having in mind the role of fungi in relation to oral cancer, were evaluated 33 patients with oral cancer, diagnosed as squamous cell carcinoma, classified as T1N0M0 or T2N0M0 . The patients were habitual drinkers and smokers, not submitted previously to any treatment related to fungi or to the present neoplasm. Samples from the oral mucosa were collected and cultured in order to identify the present yeast. Clinical aspects were also evaluated either related to the neoplasm or to candidosis. A predominance of ulcerative cancer lesions were observed, being mainly localised on the floor of the mouth. Positive cultures were represented basically by C. albicans and also six other different species isolated or in association. Pseudo-membranous or erythematous candidosis were not observed. The specificity of the identified fungi, the conditions of colonisation of these patients either related to the development of the neoplasm, immune condition or different treatments related can induce their development, leading us to attention and care for these patients in relation to the mycological aspects observed. |
publishDate |
2000 |
dc.date.none.fl_str_mv |
2000-09-29 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigos, Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/2438 10.32635/2176-9745.RBC.2000v46n3.2438 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/2438 |
identifier_str_mv |
10.32635/2176-9745.RBC.2000v46n3.2438 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/2438/1517 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
INCA |
publisher.none.fl_str_mv |
INCA |
dc.source.none.fl_str_mv |
Revista Brasileira de Cancerologia; Vol. 46 No. 3 (2000): July/Aug./Sept.; 279-82 Revista Brasileira de Cancerologia; Vol. 46 Núm. 3 (2000): jul./ago./sept.; 279-82 Revista Brasileira de Cancerologia; v. 46 n. 3 (2000): jul./ago./set.; 279-82 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
instname_str |
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
instacron_str |
INCA |
institution |
INCA |
reponame_str |
Revista Brasileira de Cancerologia (Online) |
collection |
Revista Brasileira de Cancerologia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
repository.mail.fl_str_mv |
rbc@inca.gov.br |
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1822181974696001536 |
dc.identifier.doi.none.fl_str_mv |
10.32635/2176-9745.RBC.2000v46n3.2438 |