Traitement Chimiotherapeutique Segmentaire du Cancer Mammaire par Injections Intra-Artérielles: Allié ou Non à la Chirurgie

Detalhes bibliográficos
Autor(a) principal: Coutinho, Alberto
Data de Publicação: 2023
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3729
Resumo: The A. studies some 20 cases, all considered to have no therapeutical, surgical or radiotherapical habilities. He studies the technique of intra-arterial injections (internal mammary) where the sub clavicular emerges in two different procedures: one simple dose, during the surgical act. and repeated dosis. each 6 hours, (through) a plastic catheter. Heparin is given to the patient during the repeated doses period. As chemotherapy agent, nitrogen mustard was used. Pos operative control is made (through) clinical observations and by the neoplasic cells (curve). It was observed that after 21 or 23 has there is a slow dinishing of the number of circulating cells. By this method, survey of 3 years (1 case). 2 years (4 cases), was made, but a large majointy only showed transitory improvement. Is isn’t possible to each a definite conclusion. due to few cases we have. but we shall insist in a large series, in order to be able evaluate intra-arterial chemotherapy in mammary cancer.
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spelling Traitement Chimiotherapeutique Segmentaire du Cancer Mammaire par Injections Intra-Artérielles: Allié ou Non à la ChirurgieNeoplasias da Mama/terapiaNeoplasias da Mama/cirurgiaTratamento FarmacológicoBreast Neoplasms/therapyBreast Neoplasms/surgeryDrug TherapyNeoplasias de la Mama/terapiaNeoplasias de la Mama/cirugíaQuimioterapiaThe A. studies some 20 cases, all considered to have no therapeutical, surgical or radiotherapical habilities. He studies the technique of intra-arterial injections (internal mammary) where the sub clavicular emerges in two different procedures: one simple dose, during the surgical act. and repeated dosis. each 6 hours, (through) a plastic catheter. Heparin is given to the patient during the repeated doses period. As chemotherapy agent, nitrogen mustard was used. Pos operative control is made (through) clinical observations and by the neoplasic cells (curve). It was observed that after 21 or 23 has there is a slow dinishing of the number of circulating cells. By this method, survey of 3 years (1 case). 2 years (4 cases), was made, but a large majointy only showed transitory improvement. Is isn’t possible to each a definite conclusion. due to few cases we have. but we shall insist in a large series, in order to be able evaluate intra-arterial chemotherapy in mammary cancer.O autor estuda uma série de 20 casos, todos praticamente considerados fora de possibilidades terapêuticas pela cirurgia e radioterapia habituais. Estuda a técnica da injeção intra-arterial (mamária interna) na emergência da sub clavicular em 2 procesos distintos: dose única, no momento do ato cirúrgico e doses repetidas, cada 6 horas, através um catéter de plástico. No proceso das doses repetidas, a paciente é heparinirada. Foi usado como agente quimioterápico, a Mustarda Nitrogenada. O controle post-operatório é feito pela clínica e pela curva das células neoplásicas circulantes, tendo-se observado que, a partir de 21.ª ou 23.ª horas, há um declínio lento do número de células circulantes. Obteve-se com êste método sobrevida até 3 anos (1 caso), de 2 anos (4 casos), mas a grande maioria apenas mostraram melhoras transitórias. O número ainda pequeno, não permite uma conclusão final, mas insistiremos numa série maior, para podermos julgar do valor da quimioterapia intra-arterial no câncer mamário avançado.INCA2023-09-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/372910.32635/2176-9745.RBC.1963v18n23.3729Revista Brasileira de Cancerologia; Vol. 18 No. 23 (1963): July; 33-35Revista Brasileira de Cancerologia; Vol. 18 Núm. 23 (1963): jul.; 33-35Revista Brasileira de Cancerologia; v. 18 n. 23 (1963): Jul.; 33-352176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/3729/2583https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCoutinho, Alberto2023-09-05T19:47:44Zoai:rbc.inca.gov.br:article/3729Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-09-05T19:47:44Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Traitement Chimiotherapeutique Segmentaire du Cancer Mammaire par Injections Intra-Artérielles: Allié ou Non à la Chirurgie
title Traitement Chimiotherapeutique Segmentaire du Cancer Mammaire par Injections Intra-Artérielles: Allié ou Non à la Chirurgie
spellingShingle Traitement Chimiotherapeutique Segmentaire du Cancer Mammaire par Injections Intra-Artérielles: Allié ou Non à la Chirurgie
Coutinho, Alberto
Neoplasias da Mama/terapia
Neoplasias da Mama/cirurgia
Tratamento Farmacológico
Breast Neoplasms/therapy
Breast Neoplasms/surgery
Drug Therapy
Neoplasias de la Mama/terapia
Neoplasias de la Mama/cirugía
Quimioterapia
title_short Traitement Chimiotherapeutique Segmentaire du Cancer Mammaire par Injections Intra-Artérielles: Allié ou Non à la Chirurgie
title_full Traitement Chimiotherapeutique Segmentaire du Cancer Mammaire par Injections Intra-Artérielles: Allié ou Non à la Chirurgie
title_fullStr Traitement Chimiotherapeutique Segmentaire du Cancer Mammaire par Injections Intra-Artérielles: Allié ou Non à la Chirurgie
title_full_unstemmed Traitement Chimiotherapeutique Segmentaire du Cancer Mammaire par Injections Intra-Artérielles: Allié ou Non à la Chirurgie
title_sort Traitement Chimiotherapeutique Segmentaire du Cancer Mammaire par Injections Intra-Artérielles: Allié ou Non à la Chirurgie
author Coutinho, Alberto
author_facet Coutinho, Alberto
author_role author
dc.contributor.author.fl_str_mv Coutinho, Alberto
dc.subject.por.fl_str_mv Neoplasias da Mama/terapia
Neoplasias da Mama/cirurgia
Tratamento Farmacológico
Breast Neoplasms/therapy
Breast Neoplasms/surgery
Drug Therapy
Neoplasias de la Mama/terapia
Neoplasias de la Mama/cirugía
Quimioterapia
topic Neoplasias da Mama/terapia
Neoplasias da Mama/cirurgia
Tratamento Farmacológico
Breast Neoplasms/therapy
Breast Neoplasms/surgery
Drug Therapy
Neoplasias de la Mama/terapia
Neoplasias de la Mama/cirugía
Quimioterapia
description The A. studies some 20 cases, all considered to have no therapeutical, surgical or radiotherapical habilities. He studies the technique of intra-arterial injections (internal mammary) where the sub clavicular emerges in two different procedures: one simple dose, during the surgical act. and repeated dosis. each 6 hours, (through) a plastic catheter. Heparin is given to the patient during the repeated doses period. As chemotherapy agent, nitrogen mustard was used. Pos operative control is made (through) clinical observations and by the neoplasic cells (curve). It was observed that after 21 or 23 has there is a slow dinishing of the number of circulating cells. By this method, survey of 3 years (1 case). 2 years (4 cases), was made, but a large majointy only showed transitory improvement. Is isn’t possible to each a definite conclusion. due to few cases we have. but we shall insist in a large series, in order to be able evaluate intra-arterial chemotherapy in mammary cancer.
publishDate 2023
dc.date.none.fl_str_mv 2023-09-05
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3729
10.32635/2176-9745.RBC.1963v18n23.3729
url https://rbc.inca.gov.br/index.php/revista/article/view/3729
identifier_str_mv 10.32635/2176-9745.RBC.1963v18n23.3729
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3729/2583
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 18 No. 23 (1963): July; 33-35
Revista Brasileira de Cancerologia; Vol. 18 Núm. 23 (1963): jul.; 33-35
Revista Brasileira de Cancerologia; v. 18 n. 23 (1963): Jul.; 33-35
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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