Influence of Antineoplastic Treatment on Bioelectrical Impedance Vector in Women with Malignant Breast Neoplasm

Detalhes bibliográficos
Autor(a) principal: Barros, Natássia Ellen Rodrigues Paiva
Data de Publicação: 2015
Outros Autores: Bernhard, Maria Cristina Câmara, Carioca, Antônio Augusto, Damasceno, Nágila Raquel Teixeira, Verde, Sara Maria Moreira Lima
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/252
Resumo: Introduction: Chemotherapy appears to promote increased weight and fat percentage, which are in connection with the development of mammary carcinogenesis. Objective: To evaluate the influence of the anti-cancer treatment on body composition and bioelectrical impedance vectors in women with breast cancer. Method: Observational study, both before and after, held from March 2012 to June 2013 at the General Hospital of Fortaleza (Ceará, Brazil), with 30 women with breast tumors, assessed after diagnosis and before the anti-cancer treatment (M1), and after the anticancer treatment (M2). The study collected anthropometric data, body composition and resistance values (R) and reactance (Xc) for vector analysis of bioelectrical impedance (BIVA). Results: The percentage of body fat was above the recommended levels in both instances [M1 = 35.6% (4.9) and M2 = 35.3% (4.7)] and lean body mass values were, respectively, 64 3% (4.9) 64.6% (4.7), without significant differences. The reactance (p=0.001) and the phase angle (p=0.000) had become reduced in M2. The impedance vectors, when M1 and M2 were compared, showed no significant shift (p=0,053). However, when compared with the mean vector of a reference population, it presented a significant displacement before (T2=95,2; p=0,000) and after (T2=53,2; p=0,000) the antineoplastic treatment, indicating alterations in the electrical properties of the tissue, fluid retention and loss of cell mass. Conclusion: Body composition did not change after the anti-cancer treatment. Changes in impedance vectors were suggestive of changes in the electrical properties of tissue, indicating a poorer clinical prognosis.
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spelling Influence of Antineoplastic Treatment on Bioelectrical Impedance Vector in Women with Malignant Breast NeoplasmInfluencia del Tratamiento Antineoplásico en la Bioimpedancia Vectorial Eléctrica en Pacientes con Cáncer de MamaInfluência do Tratamento Antineoplásico sobre os Vetores de Bioimpedância Elétrica em Pacientes com Câncer de MamaNeoplasias da MamaComposição CorporalQuimioterapiaImpedância ElétricaEfeitos Colaterais e Reações Adversas Relacionados a MedicamentosEstudo ObservacionalBreast NeoplasmsBody CompositionElectric ImpedanceDrug TherapyDrug-Related Side Effects and Adverse ReactionsObservational StudyNeoplasias de la MamaComposición CorporalQuimioterapiaEfectos Colaterales y Reacciones Adversas Relacionados con MedicamentosImpedancia EléctricaEstudio ObservacionalIntroduction: Chemotherapy appears to promote increased weight and fat percentage, which are in connection with the development of mammary carcinogenesis. Objective: To evaluate the influence of the anti-cancer treatment on body composition and bioelectrical impedance vectors in women with breast cancer. Method: Observational study, both before and after, held from March 2012 to June 2013 at the General Hospital of Fortaleza (Ceará, Brazil), with 30 women with breast tumors, assessed after diagnosis and before the anti-cancer treatment (M1), and after the anticancer treatment (M2). The study collected anthropometric data, body composition and resistance values (R) and reactance (Xc) for vector analysis of bioelectrical impedance (BIVA). Results: The percentage of body fat was above the recommended levels in both instances [M1 = 35.6% (4.9) and M2 = 35.3% (4.7)] and lean body mass values were, respectively, 64 3% (4.9) 64.6% (4.7), without significant differences. The reactance (p=0.001) and the phase angle (p=0.000) had become reduced in M2. The impedance vectors, when M1 and M2 were compared, showed no significant shift (p=0,053). However, when compared with the mean vector of a reference population, it presented a significant displacement before (T2=95,2; p=0,000) and after (T2=53,2; p=0,000) the antineoplastic treatment, indicating alterations in the electrical properties of the tissue, fluid retention and loss of cell mass. Conclusion: Body composition did not change after the anti-cancer treatment. Changes in impedance vectors were suggestive of changes in the electrical properties of tissue, indicating a poorer clinical prognosis.Introducción: Quimioterapia promueve el aumento en porcentaje en peso y la grasa corporal que están en conexión on el desarrollo de la carcinogénesis mamaria. Objetivo: Evaluar la influencia del tratamiento antineoplásico en la composición corporal y en la bioimpedancia vectorial eléctrica en mujeres con cáncer de mama. Método: Estudio observacional incluyendo el antes y el después, llevado de marzo de 2012 a junio de 2013 en el Hospital Geral de Fortaleza (Ceará, Brasil), con 30 mujeres con tumores de mama, evaluadas después del diagnóstico y antes del tratamiento antineoplásico (M1) y después del tratamiento antineoplásico (M2). Fueron recogidos los datos antropométricos, la composición corporal y valores de resistencia (R) y de reactancia (Xc) para Análisis de Bioimpedancia Vectorial Eléctrica (BIVA). Resultados: Los porcentajes de grasa corporal estuvieron por encima de los niveles recomendados en ambos momentos [M1=35,6%(4,9) y M2=35,3%(4,7)] y los valores de masa corporal magra fueron, respectivamente, 64,3% (4,9) 64,6% (4,7), sin diferencias significativas. La reactancia (p=0,001) y el ángulo de fase (p=0,000) se redujeron en M2. Los vectores de impedancia cuando se comparan M1 y M2 no mostraron cambio significativo (p = 0,053). Sin embargo, cuando se compara con el vector medio de una población de referencia, dichos vectores mostraron un cambio significativo antes (T2=95,2; p=0,000) y después (T2=53,2; p=0,000) del tratamiento antineoplásico, lo que indica cambios en las propiedades eléctricas del tejido, retención de líquidos y la pérdida de masa celular. Conclusión: La composición corporal no cambió después del tratamiento antineoplásico. Los cambios en los vectores de impedancia son indicadores de los cambios en las propiedades eléctricas de los tejidos, lo que indica un peor pronóstico clínico.Introdução: A quimioterapia aparece como promotora do aumento no peso e no percentual de gordura, os quais estão em conexão com o desenvolvimento da carcinogênese mamária. Objetivo: Avaliar a influência do tratamento antineoplásico sobre a composição corporal e vetores de impedância bioelétrica em mulheres com neoplasia da mama. Método: Estudo observacional, tipo antes e depois, realizado de março de 2012 a junho de 2013, no Hospital Geral de Fortaleza (Ceará, Brasil), com 30 mulheres com tumor na mama, avaliadas após o diagnóstico e antes do tratamento antineoplásico (M1), e após o tratamento antineoplásico (M2). Coletaram-se dados antropométricos, de composição corporal e valores de resistência (R) e reactância (Xc) para análise vetorial de impedância bioelétrica (BIVA). Resultados: Os percentuais de gordura corporal estiveram acima do recomendado nos dois momentos [M1= 35,6% (4,9) e M2= 35,3% (4,7)] e os valores de massa magra foram, respectivamente, 64,3% (4,9), 64,6% (4,7) sem diferenças significativas. A Reactância (p=0,001) e o ângulo de fase (p=0,000) apresentaram-se diminuídos no M2. Os vetores de impedância, quando comparados M1 e M2, não mostraram deslocamento significativo (p=0,053). Entretanto, ao serem comparados com o vetor médio de uma população de referência, apresentaram deslocamento significativo antes (T2=95,2; p=0,000) e após (T2=53,2; p=0,000) o tratamento antineoplásico, indicando alterações nas propriedades elétricas dos tecidos, retenção hídrica e perda de massa celular. Conclusão: A composição corporal não se alterou após o tratamento antineoplásico. As modificações nos vetores de impedância foram sugestivas de alterações nas propriedades elétricas dos tecidos, indicando pior prognóstico clínico.INCA2015-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/25210.32635/2176-9745.RBC.2015v61n3.252Revista Brasileira de Cancerologia; Vol. 61 No. 3 (2015): July/Aug./Sept.; 227-234Revista Brasileira de Cancerologia; Vol. 61 Núm. 3 (2015): jul./agosto/sept.; 227-234Revista Brasileira de Cancerologia; v. 61 n. 3 (2015): jul./ago./set.; 227-2342176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/252/169Barros, Natássia Ellen Rodrigues PaivaBernhard, Maria Cristina CâmaraCarioca, Antônio AugustoDamasceno, Nágila Raquel Teixeira Verde, Sara Maria Moreira Limainfo:eu-repo/semantics/openAccess2021-11-29T20:08:36Zoai:rbc.inca.gov.br:article/252Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:08:36Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Influence of Antineoplastic Treatment on Bioelectrical Impedance Vector in Women with Malignant Breast Neoplasm
Influencia del Tratamiento Antineoplásico en la Bioimpedancia Vectorial Eléctrica en Pacientes con Cáncer de Mama
Influência do Tratamento Antineoplásico sobre os Vetores de Bioimpedância Elétrica em Pacientes com Câncer de Mama
title Influence of Antineoplastic Treatment on Bioelectrical Impedance Vector in Women with Malignant Breast Neoplasm
spellingShingle Influence of Antineoplastic Treatment on Bioelectrical Impedance Vector in Women with Malignant Breast Neoplasm
Barros, Natássia Ellen Rodrigues Paiva
Neoplasias da Mama
Composição Corporal
Quimioterapia
Impedância Elétrica
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
Estudo Observacional
Breast Neoplasms
Body Composition
Electric Impedance
Drug Therapy
Drug-Related Side Effects and Adverse Reactions
Observational Study
Neoplasias de la Mama
Composición Corporal
Quimioterapia
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos
Impedancia Eléctrica
Estudio Observacional
title_short Influence of Antineoplastic Treatment on Bioelectrical Impedance Vector in Women with Malignant Breast Neoplasm
title_full Influence of Antineoplastic Treatment on Bioelectrical Impedance Vector in Women with Malignant Breast Neoplasm
title_fullStr Influence of Antineoplastic Treatment on Bioelectrical Impedance Vector in Women with Malignant Breast Neoplasm
title_full_unstemmed Influence of Antineoplastic Treatment on Bioelectrical Impedance Vector in Women with Malignant Breast Neoplasm
title_sort Influence of Antineoplastic Treatment on Bioelectrical Impedance Vector in Women with Malignant Breast Neoplasm
author Barros, Natássia Ellen Rodrigues Paiva
author_facet Barros, Natássia Ellen Rodrigues Paiva
Bernhard, Maria Cristina Câmara
Carioca, Antônio Augusto
Damasceno, Nágila Raquel Teixeira
Verde, Sara Maria Moreira Lima
author_role author
author2 Bernhard, Maria Cristina Câmara
Carioca, Antônio Augusto
Damasceno, Nágila Raquel Teixeira
Verde, Sara Maria Moreira Lima
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Barros, Natássia Ellen Rodrigues Paiva
Bernhard, Maria Cristina Câmara
Carioca, Antônio Augusto
Damasceno, Nágila Raquel Teixeira
Verde, Sara Maria Moreira Lima
dc.subject.por.fl_str_mv Neoplasias da Mama
Composição Corporal
Quimioterapia
Impedância Elétrica
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
Estudo Observacional
Breast Neoplasms
Body Composition
Electric Impedance
Drug Therapy
Drug-Related Side Effects and Adverse Reactions
Observational Study
Neoplasias de la Mama
Composición Corporal
Quimioterapia
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos
Impedancia Eléctrica
Estudio Observacional
topic Neoplasias da Mama
Composição Corporal
Quimioterapia
Impedância Elétrica
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
Estudo Observacional
Breast Neoplasms
Body Composition
Electric Impedance
Drug Therapy
Drug-Related Side Effects and Adverse Reactions
Observational Study
Neoplasias de la Mama
Composición Corporal
Quimioterapia
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos
Impedancia Eléctrica
Estudio Observacional
description Introduction: Chemotherapy appears to promote increased weight and fat percentage, which are in connection with the development of mammary carcinogenesis. Objective: To evaluate the influence of the anti-cancer treatment on body composition and bioelectrical impedance vectors in women with breast cancer. Method: Observational study, both before and after, held from March 2012 to June 2013 at the General Hospital of Fortaleza (Ceará, Brazil), with 30 women with breast tumors, assessed after diagnosis and before the anti-cancer treatment (M1), and after the anticancer treatment (M2). The study collected anthropometric data, body composition and resistance values (R) and reactance (Xc) for vector analysis of bioelectrical impedance (BIVA). Results: The percentage of body fat was above the recommended levels in both instances [M1 = 35.6% (4.9) and M2 = 35.3% (4.7)] and lean body mass values were, respectively, 64 3% (4.9) 64.6% (4.7), without significant differences. The reactance (p=0.001) and the phase angle (p=0.000) had become reduced in M2. The impedance vectors, when M1 and M2 were compared, showed no significant shift (p=0,053). However, when compared with the mean vector of a reference population, it presented a significant displacement before (T2=95,2; p=0,000) and after (T2=53,2; p=0,000) the antineoplastic treatment, indicating alterations in the electrical properties of the tissue, fluid retention and loss of cell mass. Conclusion: Body composition did not change after the anti-cancer treatment. Changes in impedance vectors were suggestive of changes in the electrical properties of tissue, indicating a poorer clinical prognosis.
publishDate 2015
dc.date.none.fl_str_mv 2015-09-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/252
10.32635/2176-9745.RBC.2015v61n3.252
url https://rbc.inca.gov.br/index.php/revista/article/view/252
identifier_str_mv 10.32635/2176-9745.RBC.2015v61n3.252
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/252/169
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 61 No. 3 (2015): July/Aug./Sept.; 227-234
Revista Brasileira de Cancerologia; Vol. 61 Núm. 3 (2015): jul./agosto/sept.; 227-234
Revista Brasileira de Cancerologia; v. 61 n. 3 (2015): jul./ago./set.; 227-234
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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