Dermatological Alterations Associated with Oncological Treatment of Women with Breast Cancer

Detalhes bibliográficos
Autor(a) principal: Kameo, Simone Yuriko
Data de Publicação: 2021
Outros Autores: Barbosa-Lima, Ricardo, Fonseca, Tiago Vasconcelos, Vassilievitch, Andressa Cabral, Marinho, Pabliane Matias Lordelo, Sawada, Namie Okino, Silva, Glebson Moura
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/1133
Resumo: Introduction: Several side effects can affect the skin and its attachments during cancer treatment of women with breast cancer, compromising the therapy. Objective: To identify the occurrence of dermatological changes during cancer treatment of women with breast cancer. Method: Quantitative approach, documentary and retrospective study, using secondary data obtained from 190 clinical records (n=190) from a private oncology service. Results: The participants had a mean age of 53 years (±11.2), with histopathological diagnosis of invasive ductal carcinoma (85.8%). All participants were exposed to chemotherapy, 65.3% to radical mastectomy and 34.2% to radiotherapy. The dermatological alterations identified, and the occurrences verified in the sample were alopecia (94.2%), hyperpigmentation (48.4%), pruritus (36.3%), erythema (6.8%), desquamation (25.8%) and nail alterations (77.9%). In all, 550 dermatological alterations were identified, resulting in an average of 2.9 (±1.3) changes per patient. Radiotherapy was associated with a higher occurrence of erythema (p<0.001) and women exposed to taxanes were more likely to manifest dermatological alterations than those unexposed (p<0.001), sociodemographic factors were not associated. Conclusion: The occurrence of dermatological alterations identified in the participants was significant, reinforcing that these manifestations may be frequent in women with breast cancer during oncological treatment, requiring prevention and treatment actions.
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spelling Dermatological Alterations Associated with Oncological Treatment of Women with Breast CancerAlteraciones Dermatológicas Asociadas con el Tratamiento Oncológico de Mujeres con Cáncer de MamaAlterações Dermatológicas Associadas ao Tratamento Oncológico de Mulheres com Câncer de MamaRadioterapia/efeitos adversosAntineoplásicos/efeitos adversosEfeitos Colaterais e Reações Adversas Relacionados a Medicamentos/radioterapiaNeoplasias da MamaDermatopatiasRadiotherapy/adverse effectsAntineoplastic Agents/adverse effectsDrug-Related Side Effects and Adverse Reactions/radiotherapyBreast NeoplasmsSkin DiseasesRadioterapia/efectos adversosAntineoplásicos/efectos adversosEfectos Colaterales y Reacciones Adversas Relacionados con Medicamentos/radioterapiaNeoplasias de la MamaEnfermedades de la PielIntroduction: Several side effects can affect the skin and its attachments during cancer treatment of women with breast cancer, compromising the therapy. Objective: To identify the occurrence of dermatological changes during cancer treatment of women with breast cancer. Method: Quantitative approach, documentary and retrospective study, using secondary data obtained from 190 clinical records (n=190) from a private oncology service. Results: The participants had a mean age of 53 years (±11.2), with histopathological diagnosis of invasive ductal carcinoma (85.8%). All participants were exposed to chemotherapy, 65.3% to radical mastectomy and 34.2% to radiotherapy. The dermatological alterations identified, and the occurrences verified in the sample were alopecia (94.2%), hyperpigmentation (48.4%), pruritus (36.3%), erythema (6.8%), desquamation (25.8%) and nail alterations (77.9%). In all, 550 dermatological alterations were identified, resulting in an average of 2.9 (±1.3) changes per patient. Radiotherapy was associated with a higher occurrence of erythema (p<0.001) and women exposed to taxanes were more likely to manifest dermatological alterations than those unexposed (p<0.001), sociodemographic factors were not associated. Conclusion: The occurrence of dermatological alterations identified in the participants was significant, reinforcing that these manifestations may be frequent in women with breast cancer during oncological treatment, requiring prevention and treatment actions.Introducción: Varios efectos secundarios pueden afectar la piel y sus uniones durante el tratamiento del cáncer de mujeres con cáncer de mama, comprometiendo la terapia. Objetivo: Identificar la aparición de alteraciones dermatológicas durante el tratamiento del cáncer de mujeres con cáncer de mama. Método: Estudio documental y retrospectivo, de carácter cuantitativo, utilizando datos secundarios obtenidos de 190 registros clínicos (n=190) de un servicio oncológico privado. Resultados: Los participantes tenían una edad media de 53 años (±11,2), con diagnóstico histopatológico de carcinoma ductal invasivo (85,8%). Todas fueran sometidas a quimioterapia, el 65,3% a mastectomía radical y el 34,2% a radioterapia. Las alteraciones dermatológicas identificadas y las ocurrencias verificadas en la muestra fueron alopecia (94,2%), hiperpigmentación (48,4%), prurito (36,3%), eritema (6,8%), descamación (25,8%) y alteraciones en las uñas (77,9%). En total, se identificaron 550 alteraciones dermatológicas, lo que resultó en un promedio de 2,9 (±1,3) por paciente. En total, se identificaron 550 cambios dermatológicos, lo que resultó en un promedio de 2,9 (±1,3) alteraciones por paciente. La radioterapia se asoció con una mayor incidencia de eritema (p<0,001) y las mujeres expuestas a taxanos tienen más probabilidades de manifestar alteraciones dermatológicas que las no expuestas (p<0,001), además de que no se asociaron factores sociodemográficos. Conclusión: La ocurrencia de alteraciones dermatológicas identificadas en las participantes fue significativa, reforzando que estas manifestaciones pueden ser frecuentes en mujeres con cáncer de mama durante el tratamiento oncológico, requiriendo acciones de prevención y tratamiento.Introdução: Diversos efeitos colaterais podem acometer a pele e seus anexos durante o tratamento oncológico de mulheres com câncer de mama, comprometendo a terapia. Objetivo: Identificar a ocorrência de alterações dermatológicas durante o tratamento oncológico de mulheres com câncer de mama. Método: Estudo documental e retrospectivo, de cunho quantitativo, com uso de dados secundários obtidos por meio de 190 prontuários clínicos (n=190) de um serviço privado de oncologia. Resultados: As participantes apresentaram média de idade de 53 anos (±11,2), com diagnóstico histopatológico de carcinoma ductal invasivo (85,8%). Todas foram submetidas à quimioterapia, 65,3% à mastectomia radical e 34,2% à radioterapia. As alterações dermatológicas identificadas e as ocorrências verificadas na amostra foram alopecia (94,2%), hiperpigmentação (48,4%), prurido (36,3%), eritema (6,8%), descamação (25,8%) e alterações ungueais (77,9%). Ao todo, foram identificadas 550 alterações dermatológicas, resultando em uma média de 2,9 (±1,3) por paciente. A radioterapia esteve associada a uma maior ocorrência de eritema (p<0,001) e mulheres expostas a taxanos apresentaram maior probabilidade de manifestar de alterações dermatológicas do que as não expostas (p<0,001), bem como fatores sociodemográficos não estiveram associados. Conclusão: A ocorrência de alterações dermatológicas identificadas nas participantes foi significativa, reforçando que essas manifestações podem ser frequentes em mulheres com câncer de mama durante o tratamento oncológico, requerendo medidas de prevenção e tratamento.INCA2021-03-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/113310.32635/2176-9745.RBC.2021v67n2.1133Revista Brasileira de Cancerologia; Vol. 67 No. 2 (2021): Apr./May/June; e-071133Revista Brasileira de Cancerologia; Vol. 67 Núm. 2 (2021): abr./mayo/jun.; e-071133Revista Brasileira de Cancerologia; v. 67 n. 2 (2021): abr./maio/jun.; e-0711332176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporenghttps://rbc.inca.gov.br/index.php/revista/article/view/1133/1000https://rbc.inca.gov.br/index.php/revista/article/view/1133/1357Copyright (c) 2021 Revista Brasileira de Cancerologiainfo:eu-repo/semantics/openAccessKameo, Simone YurikoBarbosa-Lima, RicardoFonseca, Tiago Vasconcelos Vassilievitch, Andressa Cabral Marinho, Pabliane Matias Lordelo Sawada, Namie Okino Silva, Glebson Moura 2021-11-29T18:27:33Zoai:rbc.inca.gov.br:article/1133Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T18:27:33Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Dermatological Alterations Associated with Oncological Treatment of Women with Breast Cancer
Alteraciones Dermatológicas Asociadas con el Tratamiento Oncológico de Mujeres con Cáncer de Mama
Alterações Dermatológicas Associadas ao Tratamento Oncológico de Mulheres com Câncer de Mama
title Dermatological Alterations Associated with Oncological Treatment of Women with Breast Cancer
spellingShingle Dermatological Alterations Associated with Oncological Treatment of Women with Breast Cancer
Kameo, Simone Yuriko
Radioterapia/efeitos adversos
Antineoplásicos/efeitos adversos
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/radioterapia
Neoplasias da Mama
Dermatopatias
Radiotherapy/adverse effects
Antineoplastic Agents/adverse effects
Drug-Related Side Effects and Adverse Reactions/radiotherapy
Breast Neoplasms
Skin Diseases
Radioterapia/efectos adversos
Antineoplásicos/efectos adversos
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos/radioterapia
Neoplasias de la Mama
Enfermedades de la Piel
title_short Dermatological Alterations Associated with Oncological Treatment of Women with Breast Cancer
title_full Dermatological Alterations Associated with Oncological Treatment of Women with Breast Cancer
title_fullStr Dermatological Alterations Associated with Oncological Treatment of Women with Breast Cancer
title_full_unstemmed Dermatological Alterations Associated with Oncological Treatment of Women with Breast Cancer
title_sort Dermatological Alterations Associated with Oncological Treatment of Women with Breast Cancer
author Kameo, Simone Yuriko
author_facet Kameo, Simone Yuriko
Barbosa-Lima, Ricardo
Fonseca, Tiago Vasconcelos
Vassilievitch, Andressa Cabral
Marinho, Pabliane Matias Lordelo
Sawada, Namie Okino
Silva, Glebson Moura
author_role author
author2 Barbosa-Lima, Ricardo
Fonseca, Tiago Vasconcelos
Vassilievitch, Andressa Cabral
Marinho, Pabliane Matias Lordelo
Sawada, Namie Okino
Silva, Glebson Moura
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Kameo, Simone Yuriko
Barbosa-Lima, Ricardo
Fonseca, Tiago Vasconcelos
Vassilievitch, Andressa Cabral
Marinho, Pabliane Matias Lordelo
Sawada, Namie Okino
Silva, Glebson Moura
dc.subject.por.fl_str_mv Radioterapia/efeitos adversos
Antineoplásicos/efeitos adversos
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/radioterapia
Neoplasias da Mama
Dermatopatias
Radiotherapy/adverse effects
Antineoplastic Agents/adverse effects
Drug-Related Side Effects and Adverse Reactions/radiotherapy
Breast Neoplasms
Skin Diseases
Radioterapia/efectos adversos
Antineoplásicos/efectos adversos
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos/radioterapia
Neoplasias de la Mama
Enfermedades de la Piel
topic Radioterapia/efeitos adversos
Antineoplásicos/efeitos adversos
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/radioterapia
Neoplasias da Mama
Dermatopatias
Radiotherapy/adverse effects
Antineoplastic Agents/adverse effects
Drug-Related Side Effects and Adverse Reactions/radiotherapy
Breast Neoplasms
Skin Diseases
Radioterapia/efectos adversos
Antineoplásicos/efectos adversos
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos/radioterapia
Neoplasias de la Mama
Enfermedades de la Piel
description Introduction: Several side effects can affect the skin and its attachments during cancer treatment of women with breast cancer, compromising the therapy. Objective: To identify the occurrence of dermatological changes during cancer treatment of women with breast cancer. Method: Quantitative approach, documentary and retrospective study, using secondary data obtained from 190 clinical records (n=190) from a private oncology service. Results: The participants had a mean age of 53 years (±11.2), with histopathological diagnosis of invasive ductal carcinoma (85.8%). All participants were exposed to chemotherapy, 65.3% to radical mastectomy and 34.2% to radiotherapy. The dermatological alterations identified, and the occurrences verified in the sample were alopecia (94.2%), hyperpigmentation (48.4%), pruritus (36.3%), erythema (6.8%), desquamation (25.8%) and nail alterations (77.9%). In all, 550 dermatological alterations were identified, resulting in an average of 2.9 (±1.3) changes per patient. Radiotherapy was associated with a higher occurrence of erythema (p<0.001) and women exposed to taxanes were more likely to manifest dermatological alterations than those unexposed (p<0.001), sociodemographic factors were not associated. Conclusion: The occurrence of dermatological alterations identified in the participants was significant, reinforcing that these manifestations may be frequent in women with breast cancer during oncological treatment, requiring prevention and treatment actions.
publishDate 2021
dc.date.none.fl_str_mv 2021-03-15
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1133
10.32635/2176-9745.RBC.2021v67n2.1133
url https://rbc.inca.gov.br/index.php/revista/article/view/1133
identifier_str_mv 10.32635/2176-9745.RBC.2021v67n2.1133
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1133/1000
https://rbc.inca.gov.br/index.php/revista/article/view/1133/1357
dc.rights.driver.fl_str_mv Copyright (c) 2021 Revista Brasileira de Cancerologia
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Revista Brasileira de Cancerologia
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 67 No. 2 (2021): Apr./May/June; e-071133
Revista Brasileira de Cancerologia; Vol. 67 Núm. 2 (2021): abr./mayo/jun.; e-071133
Revista Brasileira de Cancerologia; v. 67 n. 2 (2021): abr./maio/jun.; e-071133
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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