Carcinoma do Laringe: Análise dos resultados de 57 pacientes, estádios III e IV, tratados com cirurgia e radioterapia radicais

• Autor(a) principal: Vieira, Francisco Rego
• Data de Publicação: 2023
• Outros Autores: Souhami, Luis, Canary, Paulo Cézar V., Fernandes, Erivelton F., Kligerman, Jacob
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Brasileira de Cancerologia (Online)
• Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3162
• topic: Neoplasias Laríngeas; Câncer de Laringe; Cirurgia Geral; Radioterapia; Fatores Prognósticos; Laryngeal Neoplasms; General Surgery; Radiotherapy; Prognosis

From January 1981 to December 1983, 51 patients referred to the Instituto Nacional de Câncer with advanced carcinoma of the larynx were treated by radical surgery and radiotherapy. The supraglottic region was the most commonly affected. Local control was 79% and the actuarial survival rate was 55%. Ten patients (17,5%) developed distant disease. The prognostic significance of stage T nodal involvement, resection margins and elapsed time between surgery and radiotherapy was evaluated. None of these factors influenced the local control rate. However, N2 tumors did have a worse survivalrateascomparedtoN0 tumors (36%) vs76%; p = 0,02). These findings suggest that the initial surgical approach should be more conservative and that radical neck dis-section does not seem to improve local control or to reduce mortality rate.