Adenocarcinoma of Small Intestine in Adolescents: Case Report

Detalhes bibliográficos
Autor(a) principal: Fontes, Angélica Ramos Lira
Data de Publicação: 2015
Outros Autores: Botelho, Luís Fábio Barbosa, Paz, Alexandre Rolim da
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/771
Resumo: Introduction: Infantile and juvenile cancer accounts for 2-3% of all malignant tumors, being leukemia, lymphoma and central nervous system tumors the most common pediatric neoplasias. The small intestine cancer is rare, presenting major incidence in individuals aged over 40. Adenocarcinoma represents approximately 30-40% of the cases. Diagnosis is usually late due to low clinical suspicion and the unspecific symptomatology. Treatment can include surgical resection and/or chemotherapy, presenting a survival rate in 5 years of 20-30%. Case report: The case of an adolescent with small intestine adenocarcinoma was described. Anemia, abdominal pain and signs of intestinal obstruction were predominant in clinical features. The diagnosis was confirmed by means of immunohistochemistry after six months of the symptoms onset, presenting advanced staging that hindered the healing therapy. Conclusion: The low prevalence and the unspecific symptomatology can justify the late diagnosis and, consequently, the poor prognosis. In this context, the immunohistochemistry takes over a relevant role in the confirmation of the tumor origin. The early diagnosis and the advances in the treatment can, however, improve the survival in this type of cancer.
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spelling Adenocarcinoma of Small Intestine in Adolescents: Case ReportAdenocarcinoma del Intestino Delgado en Adolescente: Relato de CasoAdenocarcinoma de Intestino Delgado em Adolescente: Relato de CasoNeoplasias IntestinaisAdenocarcinomaAdolescenteRelatos de CasosIntestinal NeoplasmsAdenocarcinomaAdolescentCase ReportsNeoplasias IntestinalesAdenocarcinomaAdolescenteInformes de CasosIntroduction: Infantile and juvenile cancer accounts for 2-3% of all malignant tumors, being leukemia, lymphoma and central nervous system tumors the most common pediatric neoplasias. The small intestine cancer is rare, presenting major incidence in individuals aged over 40. Adenocarcinoma represents approximately 30-40% of the cases. Diagnosis is usually late due to low clinical suspicion and the unspecific symptomatology. Treatment can include surgical resection and/or chemotherapy, presenting a survival rate in 5 years of 20-30%. Case report: The case of an adolescent with small intestine adenocarcinoma was described. Anemia, abdominal pain and signs of intestinal obstruction were predominant in clinical features. The diagnosis was confirmed by means of immunohistochemistry after six months of the symptoms onset, presenting advanced staging that hindered the healing therapy. Conclusion: The low prevalence and the unspecific symptomatology can justify the late diagnosis and, consequently, the poor prognosis. In this context, the immunohistochemistry takes over a relevant role in the confirmation of the tumor origin. The early diagnosis and the advances in the treatment can, however, improve the survival in this type of cancer.Introducción: El cáncer infantojuvenil constituye del 2% al 3% de todos los tumores malignos, siendo las leucemias, los linfomas y los tumores del Sistema Nervioso Central las neoplasias pediátricas más corrientes. El cáncer de intestino delgado es raro, presentando mayor presencia en individuos con más de 40 años. El adenocarcinoma representa cerca del 30% al 40% de los casos. El diagnóstico es generalmente tardío, por causa de la baja sospecha clínica y de la sintomatología inespecífica. El tratamiento puede englobar resección quirúrgica y/o quimioterapia, ofreciendo al 20% o al 30% una tasa de sobrevivencia de 5 años. Relato de caso: Describimos el caso de un adolescente  con adenocarcinoma de intestino delgado. Anemia, dolor abdominal y señales de obstrucción intestinal dominaron el cuadro clínico. El diagnóstico fue confirmado por inmunohistoquímica luego de transcurridos seis meses del inicio de los síntomas, exhibiendo una estadificación evolucionada que frenó la terapia curativa. Conclusión: La baja prevalencia y la sintomatología inespecífica pueden explicar el retraso en el diagnóstico y por consiguiente, el mal pronóstico. En este contexto, la inmunohistoquímica asume un papel sobresaliente en la confirmación del origen tumoral. El diagnóstico precoz y los avances en el tratamiento pueden, por lo tanto, prosperar la sobrevida en ese tipo de cáncer.Introdução: O câncer infantojuvenil corresponde de 2% a 3% de todos os tumores malignos, sendo as leucemias, os linfomas e os tumores do Sistema Nervoso Central as neoplasias pediátricas mais comuns. O câncer de intestino delgado é raro, apresentando maior incidência em indivíduos com mais de 40 anos. O adenocarcinoma representa cerca de 30% a 40% dos casos. O diagnóstico é geralmente tardio, devido à baixa suspeição clínica e à sintomatologia inespecífica. O tratamento pode incluir ressecção cirúrgica e/ou quimioterapia, apresentando uma taxa de sobrevida em cinco anos de 20% a 30%. Relato de caso: Descreveu-se o caso de um adolescente com adenocarcinoma de intestino delgado. Anemia, dor abdominal e sinais de obstrução intestinal dominaram o quadro clínico. O diagnóstico foi confirmado por imuno-histoquímica após seis meses do início dos sintomas, apresentando um estadiamento avançado que impossibilitou a terapia curativa. Conclusão: A baixa prevalência e a sintomatologia inespecífica podem justificar o atraso diagnóstico e, consequentemente, o prognóstico ruim. Nesse contexto, a imuno-histoquímica assume papel relevante na confirmação da origem tumoral. O diagnóstico precoce e os avanços no tratamento podem, portanto, melhorar a sobrevida nesse tipo de câncer.INCA2015-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de Casoapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/77110.32635/2176-9745.RBC.2015v61n1.771Revista Brasileira de Cancerologia; Vol. 61 No. 1 (2015): Jan./Feb./Mar.; 43-47Revista Brasileira de Cancerologia; Vol. 61 Núm. 1 (2015): enero/feb./marzo; 43-47Revista Brasileira de Cancerologia; v. 61 n. 1 (2015): jan./fev./mar.; 43-472176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/771/491Fontes, Angélica Ramos LiraBotelho, Luís Fábio BarbosaPaz, Alexandre Rolim dainfo:eu-repo/semantics/openAccess2021-11-29T20:09:04Zoai:rbc.inca.gov.br:article/771Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:09:04Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Adenocarcinoma of Small Intestine in Adolescents: Case Report
Adenocarcinoma del Intestino Delgado en Adolescente: Relato de Caso
Adenocarcinoma de Intestino Delgado em Adolescente: Relato de Caso
title Adenocarcinoma of Small Intestine in Adolescents: Case Report
spellingShingle Adenocarcinoma of Small Intestine in Adolescents: Case Report
Fontes, Angélica Ramos Lira
Neoplasias Intestinais
Adenocarcinoma
Adolescente
Relatos de Casos
Intestinal Neoplasms
Adenocarcinoma
Adolescent
Case Reports
Neoplasias Intestinales
Adenocarcinoma
Adolescente
Informes de Casos
title_short Adenocarcinoma of Small Intestine in Adolescents: Case Report
title_full Adenocarcinoma of Small Intestine in Adolescents: Case Report
title_fullStr Adenocarcinoma of Small Intestine in Adolescents: Case Report
title_full_unstemmed Adenocarcinoma of Small Intestine in Adolescents: Case Report
title_sort Adenocarcinoma of Small Intestine in Adolescents: Case Report
author Fontes, Angélica Ramos Lira
author_facet Fontes, Angélica Ramos Lira
Botelho, Luís Fábio Barbosa
Paz, Alexandre Rolim da
author_role author
author2 Botelho, Luís Fábio Barbosa
Paz, Alexandre Rolim da
author2_role author
author
dc.contributor.author.fl_str_mv Fontes, Angélica Ramos Lira
Botelho, Luís Fábio Barbosa
Paz, Alexandre Rolim da
dc.subject.por.fl_str_mv Neoplasias Intestinais
Adenocarcinoma
Adolescente
Relatos de Casos
Intestinal Neoplasms
Adenocarcinoma
Adolescent
Case Reports
Neoplasias Intestinales
Adenocarcinoma
Adolescente
Informes de Casos
topic Neoplasias Intestinais
Adenocarcinoma
Adolescente
Relatos de Casos
Intestinal Neoplasms
Adenocarcinoma
Adolescent
Case Reports
Neoplasias Intestinales
Adenocarcinoma
Adolescente
Informes de Casos
description Introduction: Infantile and juvenile cancer accounts for 2-3% of all malignant tumors, being leukemia, lymphoma and central nervous system tumors the most common pediatric neoplasias. The small intestine cancer is rare, presenting major incidence in individuals aged over 40. Adenocarcinoma represents approximately 30-40% of the cases. Diagnosis is usually late due to low clinical suspicion and the unspecific symptomatology. Treatment can include surgical resection and/or chemotherapy, presenting a survival rate in 5 years of 20-30%. Case report: The case of an adolescent with small intestine adenocarcinoma was described. Anemia, abdominal pain and signs of intestinal obstruction were predominant in clinical features. The diagnosis was confirmed by means of immunohistochemistry after six months of the symptoms onset, presenting advanced staging that hindered the healing therapy. Conclusion: The low prevalence and the unspecific symptomatology can justify the late diagnosis and, consequently, the poor prognosis. In this context, the immunohistochemistry takes over a relevant role in the confirmation of the tumor origin. The early diagnosis and the advances in the treatment can, however, improve the survival in this type of cancer.
publishDate 2015
dc.date.none.fl_str_mv 2015-03-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Relato de Caso
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status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/771
10.32635/2176-9745.RBC.2015v61n1.771
url https://rbc.inca.gov.br/index.php/revista/article/view/771
identifier_str_mv 10.32635/2176-9745.RBC.2015v61n1.771
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/771/491
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 61 No. 1 (2015): Jan./Feb./Mar.; 43-47
Revista Brasileira de Cancerologia; Vol. 61 Núm. 1 (2015): enero/feb./marzo; 43-47
Revista Brasileira de Cancerologia; v. 61 n. 1 (2015): jan./fev./mar.; 43-47
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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