The Impact of Use of Glutamine on Patients with Head and Neck Tumors in Radiotherapy and Chemotherapy Treatment

Detalhes bibliográficos
Autor(a) principal: Boligon, Caroline Schardong
Data de Publicação: 2011
Outros Autores: Huth, Adriane
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/683
Resumo: Introduction: Patients with head and neck neoplasia usually show malnutrition or a nutritional risk, because of common symptoms like: dysphagia, odynophagia and xerostomia. Objective: This study aimed to verify the impact of using amino glutamine in patients with head and neck neoplasia and under radiotherapy and chemotherapy treatment concomitantly. Methods: The research was quantitative, cross-sectional, descriptive and exploratory. The data was collected from nutritional evaluation, and patients chart consultation. The patients were divided in a control group (without use of glutamine) and a test group (with use of glutamine). 16 patients, 13 of which were men and three were women, participated in the research. Results: The control group presented mucositis grades I to IV while patients who used the amino glutamine showed mucositis grades I to II only. It could be observed that the Nutritional Risk Index decreased, which represents higher nutritional risk in patients from the control group only. In patients who used glutamine, this decrease was not significant. Conclusion: These results suggest that the use of glutamine in patients with head and neck tumors and under antineoplastic therapy helps to maintain their nutritional stage and to prevent mucositis throughout their treatment, mainly grades III and IV, which prevents adequate and regular eating and nourishment.  
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spelling The Impact of Use of Glutamine on Patients with Head and Neck Tumors in Radiotherapy and Chemotherapy TreatmentEl Impacto del Uso de Glutamina en Pacientes con Tumores de Cabeza y Cuello en Tratamientos de Radioterapia y QuimioterapiaO Impacto do Uso de Glutamina em Pacientes com Tumores de Cabeça e Pescoço em Tratamento Radioterápico e QuimioterápicoGlutaminaNeoplasias de Cabeça e PescoçoRadioterapiaQuimioterapiaMucositeAvaliação NutricionalGlutamineHead and Neck NeoplasmsRadiotherapyDrug TherapyMucositisNutrition AssessmentGlutaminaNeoplasias de Cabeza y CuelloRadioterapiaQuimioterapiaMucositisEvaluación NutricionalIntroduction: Patients with head and neck neoplasia usually show malnutrition or a nutritional risk, because of common symptoms like: dysphagia, odynophagia and xerostomia. Objective: This study aimed to verify the impact of using amino glutamine in patients with head and neck neoplasia and under radiotherapy and chemotherapy treatment concomitantly. Methods: The research was quantitative, cross-sectional, descriptive and exploratory. The data was collected from nutritional evaluation, and patients chart consultation. The patients were divided in a control group (without use of glutamine) and a test group (with use of glutamine). 16 patients, 13 of which were men and three were women, participated in the research. Results: The control group presented mucositis grades I to IV while patients who used the amino glutamine showed mucositis grades I to II only. It could be observed that the Nutritional Risk Index decreased, which represents higher nutritional risk in patients from the control group only. In patients who used glutamine, this decrease was not significant. Conclusion: These results suggest that the use of glutamine in patients with head and neck tumors and under antineoplastic therapy helps to maintain their nutritional stage and to prevent mucositis throughout their treatment, mainly grades III and IV, which prevents adequate and regular eating and nourishment.  Introducción: Pacientes con de neoplasias de cabeza y cuello se presentan frecuentemente desnutridos o en un riesgo nutricional debido a los frecuentes síntomas como: disfagia, odinofagia, xerostomía. Objetivo: El objetivo de este estudio fue lo de verificar el impacto del uso del aminoácido glutamina en pacientes que presentan neoplasia de cabeza y cuello y en tratamiento de quimio y radioterapia concomitante. Método: La investigación fue de carácter cuantitativo, transversal, descriptivo y exploratorio. Los datos fueron colectados a partir de evaluación nutricional y de consulta a los prontuarios de los pacientes. Los pacientes fueron divididos en grupo control (sin uso de glutamina) y grupo test (usando glutamina). Participaron del experimento 16 pacientes siendo 13 de sexo masculino y 3 del sexo femenino. Resultados: El grupo control presentó grados de mucositis de I a IV mientras que los pacientes que usaron el aminoácido glutamina presentaron solamente los grados I y II. Se puede observar que el Índice de Riesgo Nutricional presentó reducción, lo que representa riesgo nutricional mayor solamente en los pacientes del grupo control. En los pacientes que usaron glutamina la disminución no fue significativa. Conclusión: Estos resultados sugieren que el uso de glutamina en pacientes de tumores de cabeza y cuello realizando terapia antineoplásica auxilia en el tratamiento de manutención de su estado nutricional y en la prevención de la mucositis, principalmente grado III y IV, los cuales impiden la alimentación y nutrición normales y adecuadas.Introdução: Pacientes com neoplasias de cabeça e pescoço apresentam-se frequentemente desnutridos ou em risco nutricional devido aos frequentes sintomas como: disfagia, odinofagia, xerostomia. Objetivo: Este estudo teve como objetivo verificar o impacto do uso do aminoácido glutamina em pacientes apresentando neoplasia de cabeça e pescoço e em tratamento quimioterápico e radioterápico concomitante. Método: A pesquisa foi de caráter quantitativo, transversal, descritivo e exploratório. Os dados foram coletados a partir de avaliação nutricional e de consulta aos prontuários dos pacientes. Os pacientes foram divididos em grupo controle (sem usar glutamina) e grupo teste (que fizeram uso de glutamina). Participaram da pesquisa 16 pacientes, sendo 13 do sexo masculino e três do sexo feminino. Resultados: O grupo controle apresentou graus de mucosite de I a IV, enquanto que os pacientes que usaram o aminoácido glutamina apresentaram somente os graus I e II. Pôde-se observar que o Índice de Risco Nutricional apresentou redução, o que representa risco nutricional maior somente nos pacientes do grupo controle. Nos pacientes que usaram glutamina, essa diminuição não foi significativa. Conclusão: Esses resultados sugerem que o uso da glutamina em pacientes com tumores de cabeça e pescoço realizando terapia antineoplásica auxilia no decorrer do tratamento na manutenção do seu estado nutricional e na prevenção da mucosite, principalmente grau III e IV, os quais impedem alimentação e nutrição normais e adequadas.INCA2011-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/68310.32635/2176-9745.RBC.2011v57n1.683Revista Brasileira de Cancerologia; Vol. 57 No. 1 (2011): Jan./Feb./Mar.; 31-38Revista Brasileira de Cancerologia; Vol. 57 Núm. 1 (2011): ene./feb./mar.; 31-38Revista Brasileira de Cancerologia; v. 57 n. 1 (2011): jan./fev./mar.; 31-382176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/683/457Boligon, Caroline SchardongHuth, Adriane info:eu-repo/semantics/openAccess2021-11-29T20:17:28Zoai:rbc.inca.gov.br:article/683Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:17:28Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv The Impact of Use of Glutamine on Patients with Head and Neck Tumors in Radiotherapy and Chemotherapy Treatment
El Impacto del Uso de Glutamina en Pacientes con Tumores de Cabeza y Cuello en Tratamientos de Radioterapia y Quimioterapia
O Impacto do Uso de Glutamina em Pacientes com Tumores de Cabeça e Pescoço em Tratamento Radioterápico e Quimioterápico
title The Impact of Use of Glutamine on Patients with Head and Neck Tumors in Radiotherapy and Chemotherapy Treatment
spellingShingle The Impact of Use of Glutamine on Patients with Head and Neck Tumors in Radiotherapy and Chemotherapy Treatment
Boligon, Caroline Schardong
Glutamina
Neoplasias de Cabeça e Pescoço
Radioterapia
Quimioterapia
Mucosite
Avaliação Nutricional
Glutamine
Head and Neck Neoplasms
Radiotherapy
Drug Therapy
Mucositis
Nutrition Assessment
Glutamina
Neoplasias de Cabeza y Cuello
Radioterapia
Quimioterapia
Mucositis
Evaluación Nutricional
title_short The Impact of Use of Glutamine on Patients with Head and Neck Tumors in Radiotherapy and Chemotherapy Treatment
title_full The Impact of Use of Glutamine on Patients with Head and Neck Tumors in Radiotherapy and Chemotherapy Treatment
title_fullStr The Impact of Use of Glutamine on Patients with Head and Neck Tumors in Radiotherapy and Chemotherapy Treatment
title_full_unstemmed The Impact of Use of Glutamine on Patients with Head and Neck Tumors in Radiotherapy and Chemotherapy Treatment
title_sort The Impact of Use of Glutamine on Patients with Head and Neck Tumors in Radiotherapy and Chemotherapy Treatment
author Boligon, Caroline Schardong
author_facet Boligon, Caroline Schardong
Huth, Adriane
author_role author
author2 Huth, Adriane
author2_role author
dc.contributor.author.fl_str_mv Boligon, Caroline Schardong
Huth, Adriane
dc.subject.por.fl_str_mv Glutamina
Neoplasias de Cabeça e Pescoço
Radioterapia
Quimioterapia
Mucosite
Avaliação Nutricional
Glutamine
Head and Neck Neoplasms
Radiotherapy
Drug Therapy
Mucositis
Nutrition Assessment
Glutamina
Neoplasias de Cabeza y Cuello
Radioterapia
Quimioterapia
Mucositis
Evaluación Nutricional
topic Glutamina
Neoplasias de Cabeça e Pescoço
Radioterapia
Quimioterapia
Mucosite
Avaliação Nutricional
Glutamine
Head and Neck Neoplasms
Radiotherapy
Drug Therapy
Mucositis
Nutrition Assessment
Glutamina
Neoplasias de Cabeza y Cuello
Radioterapia
Quimioterapia
Mucositis
Evaluación Nutricional
description Introduction: Patients with head and neck neoplasia usually show malnutrition or a nutritional risk, because of common symptoms like: dysphagia, odynophagia and xerostomia. Objective: This study aimed to verify the impact of using amino glutamine in patients with head and neck neoplasia and under radiotherapy and chemotherapy treatment concomitantly. Methods: The research was quantitative, cross-sectional, descriptive and exploratory. The data was collected from nutritional evaluation, and patients chart consultation. The patients were divided in a control group (without use of glutamine) and a test group (with use of glutamine). 16 patients, 13 of which were men and three were women, participated in the research. Results: The control group presented mucositis grades I to IV while patients who used the amino glutamine showed mucositis grades I to II only. It could be observed that the Nutritional Risk Index decreased, which represents higher nutritional risk in patients from the control group only. In patients who used glutamine, this decrease was not significant. Conclusion: These results suggest that the use of glutamine in patients with head and neck tumors and under antineoplastic therapy helps to maintain their nutritional stage and to prevent mucositis throughout their treatment, mainly grades III and IV, which prevents adequate and regular eating and nourishment.  
publishDate 2011
dc.date.none.fl_str_mv 2011-03-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/683
10.32635/2176-9745.RBC.2011v57n1.683
url https://rbc.inca.gov.br/index.php/revista/article/view/683
identifier_str_mv 10.32635/2176-9745.RBC.2011v57n1.683
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/683/457
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 57 No. 1 (2011): Jan./Feb./Mar.; 31-38
Revista Brasileira de Cancerologia; Vol. 57 Núm. 1 (2011): ene./feb./mar.; 31-38
Revista Brasileira de Cancerologia; v. 57 n. 1 (2011): jan./fev./mar.; 31-38
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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