Acute Coronary Syndrome during Chemotherapy: Report of Three Cases

Detalhes bibliográficos
Autor(a) principal: Paiva, Carlos Eduardo
Data de Publicação: 2009
Outros Autores: Michelin, Odair Carlito, Okoshi, Katashi
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/1677
Resumo: Venous vascular events (VE) are frequently diagnosed during cancer chemotherapytreatment. The arterial VE are uncommon and can be lifethreatening if incorrectly diagnosed and treated. The authors describe three uncommon cases of acute coronary syndromes diagnosed during chemotherapy. Patient 1 had a germ cell tumor of testis and presented no risk factor for coronary diseases and was just 27 years old. However, he presented cardiac arrest and acute myocardial infarct in a post-mortem examination. Patient 2, with a lung adenocarcinome, ex-smoker and with family history of AMI, presented an acute myocardial infarct during the second cycle of gemcitabine and cisplatin regimen. Patient 3 had a squamous cell carcinoma of the right tonsil, was hypertensive, diabetic and exsmoker; however, he presented three major vascular events during chemotherapy with 5-fluorouracil and cisplatin. Cancer chemotherapy, especially when cisplatin is administered, may be uncommonly associated with coronary ischemic events.
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spelling Acute Coronary Syndrome during Chemotherapy: Report of Three CasesSíndrome Coronariana Aguda durante o Uso da Quimioterapia: Relato de Três CasosInfarto do miocárdioAntineoplásicosMyocardial infarctionAntineoplastic AgentsVenous vascular events (VE) are frequently diagnosed during cancer chemotherapytreatment. The arterial VE are uncommon and can be lifethreatening if incorrectly diagnosed and treated. The authors describe three uncommon cases of acute coronary syndromes diagnosed during chemotherapy. Patient 1 had a germ cell tumor of testis and presented no risk factor for coronary diseases and was just 27 years old. However, he presented cardiac arrest and acute myocardial infarct in a post-mortem examination. Patient 2, with a lung adenocarcinome, ex-smoker and with family history of AMI, presented an acute myocardial infarct during the second cycle of gemcitabine and cisplatin regimen. Patient 3 had a squamous cell carcinoma of the right tonsil, was hypertensive, diabetic and exsmoker; however, he presented three major vascular events during chemotherapy with 5-fluorouracil and cisplatin. Cancer chemotherapy, especially when cisplatin is administered, may be uncommonly associated with coronary ischemic events.Eventos vasculares (EV) venosos são frequentes durante o tratamento quimioterápico. Os EV arteriais são incomuns e podem ser graves se não diagnosticados e tratados corretamente. Os autores descrevem três casos incomuns de síndromes coronarianas agudas diagnosticadas durante a quimioterapia. O paciente 1, com tumor de células germinativas de testículo, não apresentava nenhum fator de risco para doença coronariana e tinha apenas 27 anos, no entanto, apresentou uma parada cardiorrespiratória com diagnóstico post-mortem de infarto agudo do miocárdio (IAM). O paciente 2, com adenocarcinoma de pulmão, era ex-tabagista, apresentava uma história familiar de coronariopatia e apresentou um IAM durante o segundo ciclo de gencitabina e cisplatina. O paciente 3, com diagnóstico de carcinoma de células escamosas de tonsila palatina direita, apresentou três eventos vasculares maiores durante o tratamento com 5-fluorouracil e cisplatina. Era hipertenso, diabético e ex-tabagista. A quimioterapia, especialmente quando utilizada a cisplatina, pode estar relacionada com eventos coronarianos agudos.INCA2009-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de Casoapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/167710.32635/2176-9745.RBC.2009v55n1.1677Revista Brasileira de Cancerologia; Vol. 55 No. 1 (2009): Jan./Feb;/Mar.; 55-58Revista Brasileira de Cancerologia; Vol. 55 Núm. 1 (2009): ene./feb./mar.; 55-58Revista Brasileira de Cancerologia; v. 55 n. 1 (2009): jan./fev./mar.; 55-582176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAenghttps://rbc.inca.gov.br/index.php/revista/article/view/1677/988https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPaiva, Carlos Eduardo Michelin, Odair Carlito Okoshi, Katashi 2023-07-25T13:23:23Zoai:rbc.inca.gov.br:article/1677Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-07-25T13:23:23Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Acute Coronary Syndrome during Chemotherapy: Report of Three Cases
Síndrome Coronariana Aguda durante o Uso da Quimioterapia: Relato de Três Casos
title Acute Coronary Syndrome during Chemotherapy: Report of Three Cases
spellingShingle Acute Coronary Syndrome during Chemotherapy: Report of Three Cases
Paiva, Carlos Eduardo
Infarto do miocárdio
Antineoplásicos
Myocardial infarction
Antineoplastic Agents
title_short Acute Coronary Syndrome during Chemotherapy: Report of Three Cases
title_full Acute Coronary Syndrome during Chemotherapy: Report of Three Cases
title_fullStr Acute Coronary Syndrome during Chemotherapy: Report of Three Cases
title_full_unstemmed Acute Coronary Syndrome during Chemotherapy: Report of Three Cases
title_sort Acute Coronary Syndrome during Chemotherapy: Report of Three Cases
author Paiva, Carlos Eduardo
author_facet Paiva, Carlos Eduardo
Michelin, Odair Carlito
Okoshi, Katashi
author_role author
author2 Michelin, Odair Carlito
Okoshi, Katashi
author2_role author
author
dc.contributor.author.fl_str_mv Paiva, Carlos Eduardo
Michelin, Odair Carlito
Okoshi, Katashi
dc.subject.por.fl_str_mv Infarto do miocárdio
Antineoplásicos
Myocardial infarction
Antineoplastic Agents
topic Infarto do miocárdio
Antineoplásicos
Myocardial infarction
Antineoplastic Agents
description Venous vascular events (VE) are frequently diagnosed during cancer chemotherapytreatment. The arterial VE are uncommon and can be lifethreatening if incorrectly diagnosed and treated. The authors describe three uncommon cases of acute coronary syndromes diagnosed during chemotherapy. Patient 1 had a germ cell tumor of testis and presented no risk factor for coronary diseases and was just 27 years old. However, he presented cardiac arrest and acute myocardial infarct in a post-mortem examination. Patient 2, with a lung adenocarcinome, ex-smoker and with family history of AMI, presented an acute myocardial infarct during the second cycle of gemcitabine and cisplatin regimen. Patient 3 had a squamous cell carcinoma of the right tonsil, was hypertensive, diabetic and exsmoker; however, he presented three major vascular events during chemotherapy with 5-fluorouracil and cisplatin. Cancer chemotherapy, especially when cisplatin is administered, may be uncommonly associated with coronary ischemic events.
publishDate 2009
dc.date.none.fl_str_mv 2009-03-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Relato de Caso
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1677
10.32635/2176-9745.RBC.2009v55n1.1677
url https://rbc.inca.gov.br/index.php/revista/article/view/1677
identifier_str_mv 10.32635/2176-9745.RBC.2009v55n1.1677
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1677/988
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 55 No. 1 (2009): Jan./Feb;/Mar.; 55-58
Revista Brasileira de Cancerologia; Vol. 55 Núm. 1 (2009): ene./feb./mar.; 55-58
Revista Brasileira de Cancerologia; v. 55 n. 1 (2009): jan./fev./mar.; 55-58
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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