Conservative Treatment of Penile Melanoma: Case Report and Literature Review

Detalhes bibliográficos
Autor(a) principal: Ornellas, Antonio Augusto
Data de Publicação: 2007
Outros Autores: Quirino, Raul, Wisnescky, Aristóteles, Rezende, José Francisco, Faria, Paulo Antonio Silvestre de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/1785
Resumo: Melanomas of the penis are highly aggressive malignant tumors. We report on a patient with a lesion confined to the prepuce and with clinically negative inguinal lymph nodes, treated conservatively. The patient underwent wide local excision (WLE) for treatment and histological diagnosis. Treatment of the inguinal region in patients with penile melanoma remains controversial, since the incidence of metastatic disease in those with early pathologicalstage disease is significantly lower. Since our patient presented penile melanoma pathological stage T2a (depth 1.9 mm, without ulceration), we chose to use pre-operative lymphoscintigraphy, intra-operative lymph node mapping, and sentinel node biopsy to evaluate inguinal metastatic involvement. Frozen sections in an excised right sentinel node were negative, and no adjuvant treatment was performed. WLE provided effective local control of the penile tumor, and the patient remains under postoperative surveillance.
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spelling Conservative Treatment of Penile Melanoma: Case Report and Literature ReviewMelanoma de Pênis Tratado Conservadoramente: Relato de Caso e Revisão da LiteraturaMelanomaPênisLinfonodosMelanomaPenisLymph nodesMelanomas of the penis are highly aggressive malignant tumors. We report on a patient with a lesion confined to the prepuce and with clinically negative inguinal lymph nodes, treated conservatively. The patient underwent wide local excision (WLE) for treatment and histological diagnosis. Treatment of the inguinal region in patients with penile melanoma remains controversial, since the incidence of metastatic disease in those with early pathologicalstage disease is significantly lower. Since our patient presented penile melanoma pathological stage T2a (depth 1.9 mm, without ulceration), we chose to use pre-operative lymphoscintigraphy, intra-operative lymph node mapping, and sentinel node biopsy to evaluate inguinal metastatic involvement. Frozen sections in an excised right sentinel node were negative, and no adjuvant treatment was performed. WLE provided effective local control of the penile tumor, and the patient remains under postoperative surveillance.Melanomas do pênis são tumores malignos muito agressivos. Descrevemos o caso de um paciente com uma lesão confinada ao prepúcio e com linfonodos inguinais clinicamente negativos, tratados conservadoramente. O paciente submeteu-se à ressecção alargada da lesão para tratamento e diagnóstico. O tratamento das regiões inguinais em pacientes com melanoma de pênis permanece controvertido, uma vez que a incidência de doença metastática é significativamente mais baixa nos pacientes com estádios patológicos iniciais. Como nesse paciente o estádio patológico do melanoma de pênis era T2a (profundidade 1,9 mm, sem ulceração), decidimos usar linfocintigrafia pré-operatória, mapeamento intra-operatório dos linfonodos e biópsia do linfonodo sentinela para avaliar o comprometimento metastático inguinal. Cortes de congelação do linfonodo sentinela direito retirado foram negativos para malignidade e nenhum tratamento adjuvante foi realizado. A ressecção alargada da lesão permitiu efetivo controle local do tumor peniano e o paciente é mantido em acompanhamento clínico pós-operatório.INCA2007-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de Casoapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/178510.32635/2176-9745.RBC.2007v53n4.1785Revista Brasileira de Cancerologia; Vol. 53 No. 4 (2007): Oct./Nov./Dec.; 437-441Revista Brasileira de Cancerologia; Vol. 53 Núm. 4 (2007): oct./nov./dic.; 437-441Revista Brasileira de Cancerologia; v. 53 n. 4 (2007): out./nov./dez.; 437-4412176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAenghttps://rbc.inca.gov.br/index.php/revista/article/view/1785/1068https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOrnellas, Antonio AugustoQuirino, Raul Wisnescky, Aristóteles Rezende, José Francisco Faria, Paulo Antonio Silvestre de 2023-07-25T14:34:20Zoai:rbc.inca.gov.br:article/1785Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-07-25T14:34:20Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Conservative Treatment of Penile Melanoma: Case Report and Literature Review
Melanoma de Pênis Tratado Conservadoramente: Relato de Caso e Revisão da Literatura
title Conservative Treatment of Penile Melanoma: Case Report and Literature Review
spellingShingle Conservative Treatment of Penile Melanoma: Case Report and Literature Review
Ornellas, Antonio Augusto
Melanoma
Pênis
Linfonodos
Melanoma
Penis
Lymph nodes
title_short Conservative Treatment of Penile Melanoma: Case Report and Literature Review
title_full Conservative Treatment of Penile Melanoma: Case Report and Literature Review
title_fullStr Conservative Treatment of Penile Melanoma: Case Report and Literature Review
title_full_unstemmed Conservative Treatment of Penile Melanoma: Case Report and Literature Review
title_sort Conservative Treatment of Penile Melanoma: Case Report and Literature Review
author Ornellas, Antonio Augusto
author_facet Ornellas, Antonio Augusto
Quirino, Raul
Wisnescky, Aristóteles
Rezende, José Francisco
Faria, Paulo Antonio Silvestre de
author_role author
author2 Quirino, Raul
Wisnescky, Aristóteles
Rezende, José Francisco
Faria, Paulo Antonio Silvestre de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Ornellas, Antonio Augusto
Quirino, Raul
Wisnescky, Aristóteles
Rezende, José Francisco
Faria, Paulo Antonio Silvestre de
dc.subject.por.fl_str_mv Melanoma
Pênis
Linfonodos
Melanoma
Penis
Lymph nodes
topic Melanoma
Pênis
Linfonodos
Melanoma
Penis
Lymph nodes
description Melanomas of the penis are highly aggressive malignant tumors. We report on a patient with a lesion confined to the prepuce and with clinically negative inguinal lymph nodes, treated conservatively. The patient underwent wide local excision (WLE) for treatment and histological diagnosis. Treatment of the inguinal region in patients with penile melanoma remains controversial, since the incidence of metastatic disease in those with early pathologicalstage disease is significantly lower. Since our patient presented penile melanoma pathological stage T2a (depth 1.9 mm, without ulceration), we chose to use pre-operative lymphoscintigraphy, intra-operative lymph node mapping, and sentinel node biopsy to evaluate inguinal metastatic involvement. Frozen sections in an excised right sentinel node were negative, and no adjuvant treatment was performed. WLE provided effective local control of the penile tumor, and the patient remains under postoperative surveillance.
publishDate 2007
dc.date.none.fl_str_mv 2007-12-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Relato de Caso
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dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1785
10.32635/2176-9745.RBC.2007v53n4.1785
url https://rbc.inca.gov.br/index.php/revista/article/view/1785
identifier_str_mv 10.32635/2176-9745.RBC.2007v53n4.1785
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1785/1068
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
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eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 53 No. 4 (2007): Oct./Nov./Dec.; 437-441
Revista Brasileira de Cancerologia; Vol. 53 Núm. 4 (2007): oct./nov./dic.; 437-441
Revista Brasileira de Cancerologia; v. 53 n. 4 (2007): out./nov./dez.; 437-441
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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