Conservative Treatment of Penile Melanoma: Case Report and Literature Review
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/1785 |
Resumo: | Melanomas of the penis are highly aggressive malignant tumors. We report on a patient with a lesion confined to the prepuce and with clinically negative inguinal lymph nodes, treated conservatively. The patient underwent wide local excision (WLE) for treatment and histological diagnosis. Treatment of the inguinal region in patients with penile melanoma remains controversial, since the incidence of metastatic disease in those with early pathologicalstage disease is significantly lower. Since our patient presented penile melanoma pathological stage T2a (depth 1.9 mm, without ulceration), we chose to use pre-operative lymphoscintigraphy, intra-operative lymph node mapping, and sentinel node biopsy to evaluate inguinal metastatic involvement. Frozen sections in an excised right sentinel node were negative, and no adjuvant treatment was performed. WLE provided effective local control of the penile tumor, and the patient remains under postoperative surveillance. |
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Conservative Treatment of Penile Melanoma: Case Report and Literature ReviewMelanoma de Pênis Tratado Conservadoramente: Relato de Caso e Revisão da LiteraturaMelanomaPênisLinfonodosMelanomaPenisLymph nodesMelanomas of the penis are highly aggressive malignant tumors. We report on a patient with a lesion confined to the prepuce and with clinically negative inguinal lymph nodes, treated conservatively. The patient underwent wide local excision (WLE) for treatment and histological diagnosis. Treatment of the inguinal region in patients with penile melanoma remains controversial, since the incidence of metastatic disease in those with early pathologicalstage disease is significantly lower. Since our patient presented penile melanoma pathological stage T2a (depth 1.9 mm, without ulceration), we chose to use pre-operative lymphoscintigraphy, intra-operative lymph node mapping, and sentinel node biopsy to evaluate inguinal metastatic involvement. Frozen sections in an excised right sentinel node were negative, and no adjuvant treatment was performed. WLE provided effective local control of the penile tumor, and the patient remains under postoperative surveillance.Melanomas do pênis são tumores malignos muito agressivos. Descrevemos o caso de um paciente com uma lesão confinada ao prepúcio e com linfonodos inguinais clinicamente negativos, tratados conservadoramente. O paciente submeteu-se à ressecção alargada da lesão para tratamento e diagnóstico. O tratamento das regiões inguinais em pacientes com melanoma de pênis permanece controvertido, uma vez que a incidência de doença metastática é significativamente mais baixa nos pacientes com estádios patológicos iniciais. Como nesse paciente o estádio patológico do melanoma de pênis era T2a (profundidade 1,9 mm, sem ulceração), decidimos usar linfocintigrafia pré-operatória, mapeamento intra-operatório dos linfonodos e biópsia do linfonodo sentinela para avaliar o comprometimento metastático inguinal. Cortes de congelação do linfonodo sentinela direito retirado foram negativos para malignidade e nenhum tratamento adjuvante foi realizado. A ressecção alargada da lesão permitiu efetivo controle local do tumor peniano e o paciente é mantido em acompanhamento clínico pós-operatório.INCA2007-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de Casoapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/178510.32635/2176-9745.RBC.2007v53n4.1785Revista Brasileira de Cancerologia; Vol. 53 No. 4 (2007): Oct./Nov./Dec.; 437-441Revista Brasileira de Cancerologia; Vol. 53 Núm. 4 (2007): oct./nov./dic.; 437-441Revista Brasileira de Cancerologia; v. 53 n. 4 (2007): out./nov./dez.; 437-4412176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAenghttps://rbc.inca.gov.br/index.php/revista/article/view/1785/1068https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOrnellas, Antonio AugustoQuirino, Raul Wisnescky, Aristóteles Rezende, José Francisco Faria, Paulo Antonio Silvestre de 2023-07-25T14:34:20Zoai:rbc.inca.gov.br:article/1785Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-07-25T14:34:20Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Conservative Treatment of Penile Melanoma: Case Report and Literature Review Melanoma de Pênis Tratado Conservadoramente: Relato de Caso e Revisão da Literatura |
title |
Conservative Treatment of Penile Melanoma: Case Report and Literature Review |
spellingShingle |
Conservative Treatment of Penile Melanoma: Case Report and Literature Review Ornellas, Antonio Augusto Melanoma Pênis Linfonodos Melanoma Penis Lymph nodes |
title_short |
Conservative Treatment of Penile Melanoma: Case Report and Literature Review |
title_full |
Conservative Treatment of Penile Melanoma: Case Report and Literature Review |
title_fullStr |
Conservative Treatment of Penile Melanoma: Case Report and Literature Review |
title_full_unstemmed |
Conservative Treatment of Penile Melanoma: Case Report and Literature Review |
title_sort |
Conservative Treatment of Penile Melanoma: Case Report and Literature Review |
author |
Ornellas, Antonio Augusto |
author_facet |
Ornellas, Antonio Augusto Quirino, Raul Wisnescky, Aristóteles Rezende, José Francisco Faria, Paulo Antonio Silvestre de |
author_role |
author |
author2 |
Quirino, Raul Wisnescky, Aristóteles Rezende, José Francisco Faria, Paulo Antonio Silvestre de |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ornellas, Antonio Augusto Quirino, Raul Wisnescky, Aristóteles Rezende, José Francisco Faria, Paulo Antonio Silvestre de |
dc.subject.por.fl_str_mv |
Melanoma Pênis Linfonodos Melanoma Penis Lymph nodes |
topic |
Melanoma Pênis Linfonodos Melanoma Penis Lymph nodes |
description |
Melanomas of the penis are highly aggressive malignant tumors. We report on a patient with a lesion confined to the prepuce and with clinically negative inguinal lymph nodes, treated conservatively. The patient underwent wide local excision (WLE) for treatment and histological diagnosis. Treatment of the inguinal region in patients with penile melanoma remains controversial, since the incidence of metastatic disease in those with early pathologicalstage disease is significantly lower. Since our patient presented penile melanoma pathological stage T2a (depth 1.9 mm, without ulceration), we chose to use pre-operative lymphoscintigraphy, intra-operative lymph node mapping, and sentinel node biopsy to evaluate inguinal metastatic involvement. Frozen sections in an excised right sentinel node were negative, and no adjuvant treatment was performed. WLE provided effective local control of the penile tumor, and the patient remains under postoperative surveillance. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-12-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Relato de Caso |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/1785 10.32635/2176-9745.RBC.2007v53n4.1785 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/1785 |
identifier_str_mv |
10.32635/2176-9745.RBC.2007v53n4.1785 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/1785/1068 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
INCA |
publisher.none.fl_str_mv |
INCA |
dc.source.none.fl_str_mv |
Revista Brasileira de Cancerologia; Vol. 53 No. 4 (2007): Oct./Nov./Dec.; 437-441 Revista Brasileira de Cancerologia; Vol. 53 Núm. 4 (2007): oct./nov./dic.; 437-441 Revista Brasileira de Cancerologia; v. 53 n. 4 (2007): out./nov./dez.; 437-441 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
instname_str |
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
instacron_str |
INCA |
institution |
INCA |
reponame_str |
Revista Brasileira de Cancerologia (Online) |
collection |
Revista Brasileira de Cancerologia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
repository.mail.fl_str_mv |
rbc@inca.gov.br |
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