Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/1673 |
Resumo: | Esophageal cancer (EC) is a type of tumor with an increasing incidence, and mortality rates close to incidence rates. Its etiology is associated with the histological type of the disease, with the squamous cell carcinoma as the most common and strongly related to smoking and alcoholic habits, as well as the adenocarcinoma associated with Barrett's esophagus. In addition to these well-known factors, the risk of developing this cancer is increased in people who ingest food and hot drinks (mate) and who have poor nutrition (hipovitaminose A, C and E); also, there is a genetic predisposition that is still poorly defined. Clinical manifestations common during the evolution of this disease include dysphagia, odynophagia, retroesternal discomfort, hiporexia, nausea, vomiting, weight loss. Such complaints deserve careful evaluation because when revealed, the disease is already, in most cases, in an advanced stage and a curative approach on these patients is not possible. Protocols for the EC treatment include surgery, chemotherapy and radiotherapy, but the best treatment is still cause for studies. This study aims to describe and analyze the profile of clinical manifestations, the relationship between the histological type and the location, age and metastatic behavior and therapy of patients with EC undergoing cancer treatment at the Oncology and Radioisotopes Center (COR), Ipatinga-MG. Retrospective analysis of records of 109 patients diagnosed with EC was made, from May 2004 to February 2007. For statistical calculations the program Epi Info 6.04d was used. |
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Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas GeraisCâncer de Esôfago: Perfil das Manifestações Clínicas, Histologia, Localização e Comportamento Metastático em Pacientes Submetidos a Tratamento Oncológico em um Centro de Referência em Minas GeraisNeoplasias esofágicasMetástase neoplásicaHistologiaEsophageal NeoplasmsNeoplasm metastasisHistologyEsophageal cancer (EC) is a type of tumor with an increasing incidence, and mortality rates close to incidence rates. Its etiology is associated with the histological type of the disease, with the squamous cell carcinoma as the most common and strongly related to smoking and alcoholic habits, as well as the adenocarcinoma associated with Barrett's esophagus. In addition to these well-known factors, the risk of developing this cancer is increased in people who ingest food and hot drinks (mate) and who have poor nutrition (hipovitaminose A, C and E); also, there is a genetic predisposition that is still poorly defined. Clinical manifestations common during the evolution of this disease include dysphagia, odynophagia, retroesternal discomfort, hiporexia, nausea, vomiting, weight loss. Such complaints deserve careful evaluation because when revealed, the disease is already, in most cases, in an advanced stage and a curative approach on these patients is not possible. Protocols for the EC treatment include surgery, chemotherapy and radiotherapy, but the best treatment is still cause for studies. This study aims to describe and analyze the profile of clinical manifestations, the relationship between the histological type and the location, age and metastatic behavior and therapy of patients with EC undergoing cancer treatment at the Oncology and Radioisotopes Center (COR), Ipatinga-MG. Retrospective analysis of records of 109 patients diagnosed with EC was made, from May 2004 to February 2007. For statistical calculations the program Epi Info 6.04d was used.O câncer de esôfago (CE) é uma neoplasia com uma incidência crescente, com taxas de mortalidade próximas às taxas de incidência. Sua etiologia está associada ao tipo histológico da doença, sendo o carcinoma de células escamosas o mais comum e fortemente relacionado ao tabagismo e etilismo, e o adenocarcinoma associado ao esôfago de Barrett. Além desses fatores sabidamente conhecidos, o risco de desenvolver este tumor está aumentado em pessoas que ingerem alimentos e bebidas quentes (mate) e que possuem nutrição deficiente (hipovitaminose A, C e E); há também uma predisposição genética que ainda é pouco definida. Manifestações clínicas comuns durante a evolução dessa doença incluem: disfagia, odinofagia, desconforto retroesternal, hiporexia, náusea, vômitos, emagrecimento. Tais queixas merecem uma avaliação criteriosa, pois, quando essas se manifestam, a doença já se encontra, na maioria das vezes, em um estágio avançado, não sendo possível uma abordagem curativa destes pacientes. Os protocolos de tratamento do CE incluem cirurgia, quimioterapia e radioterapia, mas o melhor tratamento ainda é motivo de estudos. Este trabalho teve como objetivo descrever e analisar o perfil das manifestações clínicas, a relação entre o tipo histológico e a localização, idade e comportamento metastático e terapêutica, de pacientes portadores de CE submetidos a tratamento oncológico no Centro de Oncologia e Radioisótopos (COR), Ipatinga-MG. Foi feita análise retrospectiva dos prontuários de 109 pacientes com diagnóstico de CE, de maio de 2004 a fevereiro de 2007. Para cálculos estatísticos, foi utilizado o programa Epi Info 6.04d.INCA2009-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/167310.32635/2176-9745.RBC.2009v55n1.1673Revista Brasileira de Cancerologia; Vol. 55 No. 1 (2009): Jan./Feb;/Mar.; 27-32Revista Brasileira de Cancerologia; Vol. 55 Núm. 1 (2009): ene./feb./mar.; 27-32Revista Brasileira de Cancerologia; v. 55 n. 1 (2009): jan./fev./mar.; 27-322176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/1673/984https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMonteiro, Nonato Mendonça Lott Araújo, Daniel Francisco de Bassetti-Soares, Eric Vieira, José Pedro Ferreira de Bastos Santos, Marcos Rivânio Marinho dos Oliveira Júnior, Pedro Paulo Lopes de Delgado, Tatiana Siqueira Jacques 2022-01-27T14:41:48Zoai:rbc.inca.gov.br:article/1673Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2022-01-27T14:41:48Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais Câncer de Esôfago: Perfil das Manifestações Clínicas, Histologia, Localização e Comportamento Metastático em Pacientes Submetidos a Tratamento Oncológico em um Centro de Referência em Minas Gerais |
title |
Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais |
spellingShingle |
Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais Monteiro, Nonato Mendonça Lott Neoplasias esofágicas Metástase neoplásica Histologia Esophageal Neoplasms Neoplasm metastasis Histology |
title_short |
Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais |
title_full |
Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais |
title_fullStr |
Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais |
title_full_unstemmed |
Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais |
title_sort |
Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais |
author |
Monteiro, Nonato Mendonça Lott |
author_facet |
Monteiro, Nonato Mendonça Lott Araújo, Daniel Francisco de Bassetti-Soares, Eric Vieira, José Pedro Ferreira de Bastos Santos, Marcos Rivânio Marinho dos Oliveira Júnior, Pedro Paulo Lopes de Delgado, Tatiana Siqueira Jacques |
author_role |
author |
author2 |
Araújo, Daniel Francisco de Bassetti-Soares, Eric Vieira, José Pedro Ferreira de Bastos Santos, Marcos Rivânio Marinho dos Oliveira Júnior, Pedro Paulo Lopes de Delgado, Tatiana Siqueira Jacques |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Monteiro, Nonato Mendonça Lott Araújo, Daniel Francisco de Bassetti-Soares, Eric Vieira, José Pedro Ferreira de Bastos Santos, Marcos Rivânio Marinho dos Oliveira Júnior, Pedro Paulo Lopes de Delgado, Tatiana Siqueira Jacques |
dc.subject.por.fl_str_mv |
Neoplasias esofágicas Metástase neoplásica Histologia Esophageal Neoplasms Neoplasm metastasis Histology |
topic |
Neoplasias esofágicas Metástase neoplásica Histologia Esophageal Neoplasms Neoplasm metastasis Histology |
description |
Esophageal cancer (EC) is a type of tumor with an increasing incidence, and mortality rates close to incidence rates. Its etiology is associated with the histological type of the disease, with the squamous cell carcinoma as the most common and strongly related to smoking and alcoholic habits, as well as the adenocarcinoma associated with Barrett's esophagus. In addition to these well-known factors, the risk of developing this cancer is increased in people who ingest food and hot drinks (mate) and who have poor nutrition (hipovitaminose A, C and E); also, there is a genetic predisposition that is still poorly defined. Clinical manifestations common during the evolution of this disease include dysphagia, odynophagia, retroesternal discomfort, hiporexia, nausea, vomiting, weight loss. Such complaints deserve careful evaluation because when revealed, the disease is already, in most cases, in an advanced stage and a curative approach on these patients is not possible. Protocols for the EC treatment include surgery, chemotherapy and radiotherapy, but the best treatment is still cause for studies. This study aims to describe and analyze the profile of clinical manifestations, the relationship between the histological type and the location, age and metastatic behavior and therapy of patients with EC undergoing cancer treatment at the Oncology and Radioisotopes Center (COR), Ipatinga-MG. Retrospective analysis of records of 109 patients diagnosed with EC was made, from May 2004 to February 2007. For statistical calculations the program Epi Info 6.04d was used. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-03-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigos, Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/1673 10.32635/2176-9745.RBC.2009v55n1.1673 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/1673 |
identifier_str_mv |
10.32635/2176-9745.RBC.2009v55n1.1673 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/1673/984 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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INCA |
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INCA |
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Revista Brasileira de Cancerologia; Vol. 55 No. 1 (2009): Jan./Feb;/Mar.; 27-32 Revista Brasileira de Cancerologia; Vol. 55 Núm. 1 (2009): ene./feb./mar.; 27-32 Revista Brasileira de Cancerologia; v. 55 n. 1 (2009): jan./fev./mar.; 27-32 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
instname_str |
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
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INCA |
institution |
INCA |
reponame_str |
Revista Brasileira de Cancerologia (Online) |
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Revista Brasileira de Cancerologia (Online) |
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Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
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rbc@inca.gov.br |
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