Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais

Detalhes bibliográficos
Autor(a) principal: Monteiro, Nonato Mendonça Lott
Data de Publicação: 2009
Outros Autores: Araújo, Daniel Francisco de, Bassetti-Soares, Eric, Vieira, José Pedro Ferreira de Bastos, Santos, Marcos Rivânio Marinho dos, Oliveira Júnior, Pedro Paulo Lopes de, Delgado, Tatiana Siqueira Jacques
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/1673
Resumo: Esophageal cancer (EC) is a type of tumor with an increasing incidence, and mortality rates close to incidence rates. Its etiology is associated with the histological type of the disease, with the squamous cell carcinoma as the most common and strongly related to smoking and alcoholic habits, as well as the adenocarcinoma associated with Barrett's esophagus. In addition to these well-known factors, the risk of developing this cancer is increased in people who ingest food and hot drinks (mate) and who have poor nutrition (hipovitaminose A, C and E); also, there is a genetic predisposition that is still poorly defined. Clinical manifestations common during the evolution of this disease include dysphagia, odynophagia, retroesternal discomfort, hiporexia, nausea, vomiting, weight loss. Such complaints deserve careful evaluation because when revealed, the disease is already, in most cases, in an advanced stage and a curative approach on these patients is not possible. Protocols for the EC treatment include surgery, chemotherapy and radiotherapy, but the best treatment is still cause for studies. This study aims to describe and analyze the profile of clinical manifestations, the relationship between the histological type and the location, age and metastatic behavior and therapy of patients with EC undergoing cancer treatment at the Oncology and Radioisotopes Center (COR), Ipatinga-MG. Retrospective analysis of records of 109 patients diagnosed with EC was made, from May 2004 to February 2007. For statistical calculations the program Epi Info 6.04d was used.
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spelling Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas GeraisCâncer de Esôfago: Perfil das Manifestações Clínicas, Histologia, Localização e Comportamento Metastático em Pacientes Submetidos a Tratamento Oncológico em um Centro de Referência em Minas GeraisNeoplasias esofágicasMetástase neoplásicaHistologiaEsophageal NeoplasmsNeoplasm metastasisHistologyEsophageal cancer (EC) is a type of tumor with an increasing incidence, and mortality rates close to incidence rates. Its etiology is associated with the histological type of the disease, with the squamous cell carcinoma as the most common and strongly related to smoking and alcoholic habits, as well as the adenocarcinoma associated with Barrett's esophagus. In addition to these well-known factors, the risk of developing this cancer is increased in people who ingest food and hot drinks (mate) and who have poor nutrition (hipovitaminose A, C and E); also, there is a genetic predisposition that is still poorly defined. Clinical manifestations common during the evolution of this disease include dysphagia, odynophagia, retroesternal discomfort, hiporexia, nausea, vomiting, weight loss. Such complaints deserve careful evaluation because when revealed, the disease is already, in most cases, in an advanced stage and a curative approach on these patients is not possible. Protocols for the EC treatment include surgery, chemotherapy and radiotherapy, but the best treatment is still cause for studies. This study aims to describe and analyze the profile of clinical manifestations, the relationship between the histological type and the location, age and metastatic behavior and therapy of patients with EC undergoing cancer treatment at the Oncology and Radioisotopes Center (COR), Ipatinga-MG. Retrospective analysis of records of 109 patients diagnosed with EC was made, from May 2004 to February 2007. For statistical calculations the program Epi Info 6.04d was used.O câncer de esôfago (CE) é uma neoplasia com uma incidência crescente, com taxas de mortalidade próximas às taxas de incidência. Sua etiologia está associada ao tipo histológico da doença, sendo o carcinoma de células escamosas o mais comum e fortemente relacionado ao tabagismo e etilismo, e o adenocarcinoma associado ao esôfago de Barrett. Além desses fatores sabidamente conhecidos, o risco de desenvolver este tumor está aumentado em pessoas que ingerem alimentos e bebidas quentes (mate) e que possuem nutrição deficiente (hipovitaminose A, C e E); há também uma predisposição genética que ainda é pouco definida. Manifestações clínicas comuns durante a evolução dessa doença incluem: disfagia, odinofagia, desconforto retroesternal, hiporexia, náusea, vômitos, emagrecimento. Tais queixas merecem uma avaliação criteriosa, pois, quando essas se manifestam, a doença já se encontra, na maioria das vezes, em um estágio avançado, não sendo possível uma abordagem curativa destes pacientes. Os protocolos de tratamento do CE incluem cirurgia, quimioterapia e radioterapia, mas o melhor tratamento ainda é motivo de estudos. Este trabalho teve como objetivo descrever e analisar o perfil das manifestações clínicas, a relação entre o tipo histológico e a localização, idade e comportamento metastático e terapêutica, de pacientes portadores de CE submetidos a tratamento oncológico no Centro de Oncologia e Radioisótopos (COR), Ipatinga-MG. Foi feita análise retrospectiva dos prontuários de 109 pacientes com diagnóstico de CE, de maio de 2004 a fevereiro de 2007. Para cálculos estatísticos, foi utilizado o programa Epi Info 6.04d.INCA2009-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/167310.32635/2176-9745.RBC.2009v55n1.1673Revista Brasileira de Cancerologia; Vol. 55 No. 1 (2009): Jan./Feb;/Mar.; 27-32Revista Brasileira de Cancerologia; Vol. 55 Núm. 1 (2009): ene./feb./mar.; 27-32Revista Brasileira de Cancerologia; v. 55 n. 1 (2009): jan./fev./mar.; 27-322176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/1673/984https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMonteiro, Nonato Mendonça Lott Araújo, Daniel Francisco de Bassetti-Soares, Eric Vieira, José Pedro Ferreira de Bastos Santos, Marcos Rivânio Marinho dos Oliveira Júnior, Pedro Paulo Lopes de Delgado, Tatiana Siqueira Jacques 2022-01-27T14:41:48Zoai:rbc.inca.gov.br:article/1673Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2022-01-27T14:41:48Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais
Câncer de Esôfago: Perfil das Manifestações Clínicas, Histologia, Localização e Comportamento Metastático em Pacientes Submetidos a Tratamento Oncológico em um Centro de Referência em Minas Gerais
title Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais
spellingShingle Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais
Monteiro, Nonato Mendonça Lott
Neoplasias esofágicas
Metástase neoplásica
Histologia
Esophageal Neoplasms
Neoplasm metastasis
Histology
title_short Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais
title_full Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais
title_fullStr Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais
title_full_unstemmed Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais
title_sort Esophageal Cancer: Profile of Clinical Manifestations, Histology, Location and Metastatic Behavior in Patients Undergoing Cancer Treatment at a Cancer Center in Minas Gerais
author Monteiro, Nonato Mendonça Lott
author_facet Monteiro, Nonato Mendonça Lott
Araújo, Daniel Francisco de
Bassetti-Soares, Eric
Vieira, José Pedro Ferreira de Bastos
Santos, Marcos Rivânio Marinho dos
Oliveira Júnior, Pedro Paulo Lopes de
Delgado, Tatiana Siqueira Jacques
author_role author
author2 Araújo, Daniel Francisco de
Bassetti-Soares, Eric
Vieira, José Pedro Ferreira de Bastos
Santos, Marcos Rivânio Marinho dos
Oliveira Júnior, Pedro Paulo Lopes de
Delgado, Tatiana Siqueira Jacques
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Monteiro, Nonato Mendonça Lott
Araújo, Daniel Francisco de
Bassetti-Soares, Eric
Vieira, José Pedro Ferreira de Bastos
Santos, Marcos Rivânio Marinho dos
Oliveira Júnior, Pedro Paulo Lopes de
Delgado, Tatiana Siqueira Jacques
dc.subject.por.fl_str_mv Neoplasias esofágicas
Metástase neoplásica
Histologia
Esophageal Neoplasms
Neoplasm metastasis
Histology
topic Neoplasias esofágicas
Metástase neoplásica
Histologia
Esophageal Neoplasms
Neoplasm metastasis
Histology
description Esophageal cancer (EC) is a type of tumor with an increasing incidence, and mortality rates close to incidence rates. Its etiology is associated with the histological type of the disease, with the squamous cell carcinoma as the most common and strongly related to smoking and alcoholic habits, as well as the adenocarcinoma associated with Barrett's esophagus. In addition to these well-known factors, the risk of developing this cancer is increased in people who ingest food and hot drinks (mate) and who have poor nutrition (hipovitaminose A, C and E); also, there is a genetic predisposition that is still poorly defined. Clinical manifestations common during the evolution of this disease include dysphagia, odynophagia, retroesternal discomfort, hiporexia, nausea, vomiting, weight loss. Such complaints deserve careful evaluation because when revealed, the disease is already, in most cases, in an advanced stage and a curative approach on these patients is not possible. Protocols for the EC treatment include surgery, chemotherapy and radiotherapy, but the best treatment is still cause for studies. This study aims to describe and analyze the profile of clinical manifestations, the relationship between the histological type and the location, age and metastatic behavior and therapy of patients with EC undergoing cancer treatment at the Oncology and Radioisotopes Center (COR), Ipatinga-MG. Retrospective analysis of records of 109 patients diagnosed with EC was made, from May 2004 to February 2007. For statistical calculations the program Epi Info 6.04d was used.
publishDate 2009
dc.date.none.fl_str_mv 2009-03-31
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url https://rbc.inca.gov.br/index.php/revista/article/view/1673
identifier_str_mv 10.32635/2176-9745.RBC.2009v55n1.1673
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dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1673/984
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dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 55 No. 1 (2009): Jan./Feb;/Mar.; 27-32
Revista Brasileira de Cancerologia; Vol. 55 Núm. 1 (2009): ene./feb./mar.; 27-32
Revista Brasileira de Cancerologia; v. 55 n. 1 (2009): jan./fev./mar.; 27-32
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
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reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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