Radiographic Evaluation of the Maxilla and Mandible of Patients Diagnosed with Multiple Myeloma: Retrospective Study

• Autor(a) principal: Costa, Ana Maria Dias da
• Data de Publicação: 2022
• Outros Autores: Costa , Cleiton Rodrigues da, Pereira , Débora Lima, Antunes , Héliton Spindola
• Tipo de documento: Artigo
• Idioma: por; eng
• Título da fonte: Revista Brasileira de Cancerologia (Online)
• Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/2186
• topic: mieloma múltiplo/diagnóstico; mandíbula; maxila; radiografia panorâmica; diagnóstico por imagem; multiple myeloma/diagnosis; mandible; maxilla; radiography, panoramic; diagnostic imaging; mieloma múltiple/diagnóstico; mandíbula; maxilar; radiografía panorámica; diagnóstico por imagen

Introduction: Multiple myeloma is defined as a plasma cells malignant neoplasm with abnormal proliferation of clonal plasma cells in the bone marrow of unknown etiology. Objective: To characterize patients with multiple myeloma treated at INCA’s Department of Stomato-Dentistry and Prosthodontics, utilizing sociodemographic, clinical, laboratory and radiographic data. Method: Retrospective cross-sectional study of patients diagnosed with multiple myeloma from 2000 to 2018 who underwent panoramic radiography at the diagnosis of the disease. The sociodemographic and clinical-radiographic data of the study population were collected from the patients’ medical records stored in a database, analyzed descriptively and submitted to the X2 non-parametric test (chi-square). Results: In the final sample, 163 cases were totaled, mostly men (56.4%), white (55.8%), aged ≤55 years (54%), with incomplete elementary education (30.7%), non-smokers (54.6%), and non-alcoholics (54.6%). There were lytic lesions in 46 patients (28.2%) concentrated in the mandible (82.6%; p=0.000). Higher frequency of partially defined margins (50.0%), non-sclerotic (78.2%) and unilocular aspect (43.5%) were found. Of the 46 patients who presented with a maxillomandibular lytic lesion, 27 were older than 55 years (p=0.042). Conclusion: There was higher occurrence of bone lesions in the mandible when compared to the maxilla.