Soft Tissue Sarcomas: Treatment Results in Low-grade Tumors

Detalhes bibliográficos
Autor(a) principal: Manoel, Wilmar José
Data de Publicação: 2008
Outros Autores: Sarmento, Bruno José de Queiroz, Silveira Júnior, Luiz de Paula, Abreu, Deidimar Cássia Batista de, Abreu Neto, Iron Pires de, Ferreira, Erika Chaul
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/1754
Resumo: Objectives: The objectives were to describe the experience at our hospital's Soft Tissue Department in the treatment of low-grade sarcomas and to analyze factors associated with local recurrence. Methods: Seventy-six patients were analyzed retrospectively. Information was recorded on pain, previous surgery, localization, histopathology, surgical treatment, recurrences, and evolution. Results: Overall 5-year survival was 94%, local failure occurred in 17 patients (22.3%), and 9 (11.8%) presented metastasis. Adjuvant radiotherapy was indicated in 23 patients (30.2%). Factors that influenced local recurrence were tumor size >5cm (OR 12.09; 95%CI 1.73-84.53; p=0.012) and inadequate margins (OR 47.16; 95%CI 3.42-650.33; p=0.004), identified only in the group with limb and superficial trunk sarcomas. Conclusions: The results were consistent with the literature. Tumor size >5cm and inadequate margins were the main factors for local recurrence.
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spelling Soft Tissue Sarcomas: Treatment Results in Low-grade TumorsSarcomas de Partes Moles: Resultados do Tratamento dos Tumores de Baixo GrauObjectives: The objectives were to describe the experience at our hospital's Soft Tissue Department in the treatment of low-grade sarcomas and to analyze factors associated with local recurrence. Methods: Seventy-six patients were analyzed retrospectively. Information was recorded on pain, previous surgery, localization, histopathology, surgical treatment, recurrences, and evolution. Results: Overall 5-year survival was 94%, local failure occurred in 17 patients (22.3%), and 9 (11.8%) presented metastasis. Adjuvant radiotherapy was indicated in 23 patients (30.2%). Factors that influenced local recurrence were tumor size >5cm (OR 12.09; 95%CI 1.73-84.53; p=0.012) and inadequate margins (OR 47.16; 95%CI 3.42-650.33; p=0.004), identified only in the group with limb and superficial trunk sarcomas. Conclusions: The results were consistent with the literature. Tumor size >5cm and inadequate margins were the main factors for local recurrence.Objetivos: Descrever a experiência do Serviço de Tecido Conjuntivo no tratamento dos sarcomas de baixo grau e analisar os fatores associados à recorrência local. Métodos: Setenta e seis pacientes foram analisados retrospectivamente. Informações quanto à presença de dor local, cirurgia prévia, tamanho do tumor, localização, tipo histológico, tratamento cirúrgico, recorrência e evolução foram estudados. Resultados: A sobrevida global em cinco anos foi de 94%; a recidiva local ocorreu em 17 pacientes (22,3%), e 9 pacientes (11,8%) apresentaram metástases a distância. A radioterapia adjuvante foi indicada em 23 pacientes (30,2%). Os fatores que influenciaram a recorrência local foram o tamanho do tumor >5cm (odds ratio 12,09; intervalo de confiança 95% 1,73-84,53; p=0,012) e a margem cirúrgica inadequada (odds ratio 47,16; intervalo de confiança 95% 3,42-650,33; p=0,004), identificados apenas no grupo de sarcomas de extremidades e superficiais do tronco. Conclusão: Os resultados são semelhantes aos descritos na literatura. O tamanho do tumor >5cm e a margem cirúrgica inadequada foram os principais fatores preditores de recorrência local.INCA2008-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/175410.32635/2176-9745.RBC.2008v54n1.1754Revista Brasileira de Cancerologia; Vol. 54 No. 1 (2008): Jan./Feb./Mar.; 17-24Revista Brasileira de Cancerologia; Vol. 54 Núm. 1 (2008): ene./feb./mar.; 17-24Revista Brasileira de Cancerologia; v. 54 n. 1 (2008): jan./fev./mar.; 17-242176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/1754/1044Manoel, Wilmar José Sarmento, Bruno José de Queiroz Silveira Júnior, Luiz de PaulaAbreu, Deidimar Cássia Batista de Abreu Neto, Iron Pires de Ferreira, Erika Chaulinfo:eu-repo/semantics/openAccess2021-11-29T20:24:17Zoai:rbc.inca.gov.br:article/1754Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:24:17Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Soft Tissue Sarcomas: Treatment Results in Low-grade Tumors
Sarcomas de Partes Moles: Resultados do Tratamento dos Tumores de Baixo Grau
title Soft Tissue Sarcomas: Treatment Results in Low-grade Tumors
spellingShingle Soft Tissue Sarcomas: Treatment Results in Low-grade Tumors
Manoel, Wilmar José
title_short Soft Tissue Sarcomas: Treatment Results in Low-grade Tumors
title_full Soft Tissue Sarcomas: Treatment Results in Low-grade Tumors
title_fullStr Soft Tissue Sarcomas: Treatment Results in Low-grade Tumors
title_full_unstemmed Soft Tissue Sarcomas: Treatment Results in Low-grade Tumors
title_sort Soft Tissue Sarcomas: Treatment Results in Low-grade Tumors
author Manoel, Wilmar José
author_facet Manoel, Wilmar José
Sarmento, Bruno José de Queiroz
Silveira Júnior, Luiz de Paula
Abreu, Deidimar Cássia Batista de
Abreu Neto, Iron Pires de
Ferreira, Erika Chaul
author_role author
author2 Sarmento, Bruno José de Queiroz
Silveira Júnior, Luiz de Paula
Abreu, Deidimar Cássia Batista de
Abreu Neto, Iron Pires de
Ferreira, Erika Chaul
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Manoel, Wilmar José
Sarmento, Bruno José de Queiroz
Silveira Júnior, Luiz de Paula
Abreu, Deidimar Cássia Batista de
Abreu Neto, Iron Pires de
Ferreira, Erika Chaul
description Objectives: The objectives were to describe the experience at our hospital's Soft Tissue Department in the treatment of low-grade sarcomas and to analyze factors associated with local recurrence. Methods: Seventy-six patients were analyzed retrospectively. Information was recorded on pain, previous surgery, localization, histopathology, surgical treatment, recurrences, and evolution. Results: Overall 5-year survival was 94%, local failure occurred in 17 patients (22.3%), and 9 (11.8%) presented metastasis. Adjuvant radiotherapy was indicated in 23 patients (30.2%). Factors that influenced local recurrence were tumor size >5cm (OR 12.09; 95%CI 1.73-84.53; p=0.012) and inadequate margins (OR 47.16; 95%CI 3.42-650.33; p=0.004), identified only in the group with limb and superficial trunk sarcomas. Conclusions: The results were consistent with the literature. Tumor size >5cm and inadequate margins were the main factors for local recurrence.
publishDate 2008
dc.date.none.fl_str_mv 2008-03-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1754
10.32635/2176-9745.RBC.2008v54n1.1754
url https://rbc.inca.gov.br/index.php/revista/article/view/1754
identifier_str_mv 10.32635/2176-9745.RBC.2008v54n1.1754
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1754/1044
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 54 No. 1 (2008): Jan./Feb./Mar.; 17-24
Revista Brasileira de Cancerologia; Vol. 54 Núm. 1 (2008): ene./feb./mar.; 17-24
Revista Brasileira de Cancerologia; v. 54 n. 1 (2008): jan./fev./mar.; 17-24
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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