Cutaneous Melanoma in a University Hospital, 2001-2016
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/911 |
Resumo: | Introduction: Melanoma is the main cause of death among primary skin neoplasms. The worldwide incidence has been increasing, however there is scarce national epidemiological information. Objective: Analyze the epidemiological and histopathological profile of cutaneous melanomas diagnosed at a university hospital in the last 16 years. Method: Historical series of cutaneous melanoma cases from review of charts and histopathological reports from 2001 to 2016. Results: The mean frequency over the years was 2.99 melanomas for every 1,000 new outpatient visits. The casuistry consisted of 224 cases of cutaneous melanomas in 211 patients, Caucasians (98.6%), women (55.9%), with mean age of 57.3 years. The mean time between onset of the lesion (time since the appearance of the lesion or since it began to change reported by the patient) and diagnosis was 4.8 years. The predominant tumor size was 0.5 to 2 cm, affecting the cephalic region in individuals older than 60 years and torso in those younger than 60 years. “Other melanomas” (34.8%) and superficial spreading melanoma (31.7%) were the predominant subtypes. Most of the cases had Breslow index ≤ 1 mm (70% of patients). The thinnest subtypes (≤ 1 mm) were superficial spreading melanoma and lentigo maligna. Nodular melanomas had intermediate Breslow (1 to 4 mm) or thick (≥ 4 mm) with high dissemination rate and lymph node metastasis. Conclusion: The frequency remained stable. Population below 60 years old had a higher prevalence. The most frequent subtypes were “other melanomas” and extensive superficial located mainly in the cephalic and torso regions. |
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Cutaneous Melanoma in a University Hospital, 2001-2016Melanoma Cutáneo en un Hospital Universitario, 2001-2016Melanoma Cutâneo em um Hospital Universitário, 2001-2016Melanoma/epidemiologiaNeoplasias Cutâneas/epidemiologiaDermatopatiasMelanoma/epidemiologySkin Neoplasms/epidemiologySkin DiseasesMelanoma/epidemiologíaNeoplasias Cutáneas/ epidemiologíaEnfermedades de la PielIntroduction: Melanoma is the main cause of death among primary skin neoplasms. The worldwide incidence has been increasing, however there is scarce national epidemiological information. Objective: Analyze the epidemiological and histopathological profile of cutaneous melanomas diagnosed at a university hospital in the last 16 years. Method: Historical series of cutaneous melanoma cases from review of charts and histopathological reports from 2001 to 2016. Results: The mean frequency over the years was 2.99 melanomas for every 1,000 new outpatient visits. The casuistry consisted of 224 cases of cutaneous melanomas in 211 patients, Caucasians (98.6%), women (55.9%), with mean age of 57.3 years. The mean time between onset of the lesion (time since the appearance of the lesion or since it began to change reported by the patient) and diagnosis was 4.8 years. The predominant tumor size was 0.5 to 2 cm, affecting the cephalic region in individuals older than 60 years and torso in those younger than 60 years. “Other melanomas” (34.8%) and superficial spreading melanoma (31.7%) were the predominant subtypes. Most of the cases had Breslow index ≤ 1 mm (70% of patients). The thinnest subtypes (≤ 1 mm) were superficial spreading melanoma and lentigo maligna. Nodular melanomas had intermediate Breslow (1 to 4 mm) or thick (≥ 4 mm) with high dissemination rate and lymph node metastasis. Conclusion: The frequency remained stable. Population below 60 years old had a higher prevalence. The most frequent subtypes were “other melanomas” and extensive superficial located mainly in the cephalic and torso regions.Introdução: El melanoma es la principal causa de muerte entre las neoplasias malignas cutaneas primarias. Su incidencia mundial ha aumentado progresivamente, sin embargo, la informacion epidemiologica nacional es escasa. Objetivo: Analizar el perfil epidemiologico e histopatologico de los melanomas cutaneos diagnosticados en un hospital universitario en 16 anos. Método: Serie historica de casos de melanoma cutaneo obtenidos por la revision de registros medicos e informes histopatologicos de 2001-2016. Resultados: La frecuencia se mantuvo con un promedio de 2,99 melanomas/mil nuevas consultas. La casuistica consistio en 224 melanomas cutaneos en 211 pacientes, blancos (98,6%), mujeres (55,9%), con edad media de 57,3 anos. El promedio entre la aparicion de la lesion (desde la aparicion o desde que comenzo a cambiar segun informe del paciente) y diagnostico fue 4,8 anos. El tamano predominante de 0,5 a 2 cm, afectando principalmente la region cefalica en mayores de 60 anos y el tronco cuando menores de 60. “Otros melanomas” (34,8%) y melanoma extenso superficial (31,7%) fueron los subtipos mas frecuentes. La mayoria de los casos tenia indice de Breslow ≤1 mm (70%). Los mas delgados (≤1 mm) fueron lentigo extenso superficial y maligno. Los nodulares tenian Breslow intermedio (1 a 4 mm) o grueso (≥4 mm) con altas tasas de diseminacion y metastasis para ganglios linfaticos. Conclusión: La frecuencia se mantuvo estable. Hubo mayor prevalencia en la poblacion menor de 60 anos. Los subtipos mas frecuentes fueron “otros melanomas” y extensos superficiales con localizacion principalmente cefalica y del tronco.Introdução: O melanoma e a principal causa de morte entre as neoplasias malignas cutâneas primarias. Sua incidência mundial vem aumentando progressivamente, entretanto, existem escassas informações epidemiológicas nacionais. Objetivo: Analisar os perfis epidemiológico e histopatológico de melanomas cutâneos diagnosticados em hospital universitário nos últimos 16 anos. Método: Serie histórica de casos de melanoma cutâneo realizada por meio da revisão de prontuários e laudos histopatológicos de 2001 a 2016. Resultados: A frequência manteve-se com média de 2,99 melanomas por mil novos atendimentos ambulatoriais. A casuística foi de 224 melanomas cutâneos em 211 pacientes, brancos (98,6%), mulheres (55,9%), com idade média de 57,3 anos. O tempo médio entre o aparecimento da lesão (desde surgimento da lesão ou desde que a lesão começou a se modificar, relatado pelo paciente) e o diagnóstico foi 4,8 anos. O tamanho predominante foi de 0,5 a 2 cm, acometendo principalmente a região cefálica em indivíduos maiores de 60 anos e troncular naqueles menores de 60 anos. “Outros melanomas” (34,8%) e melanoma extensivo superficial (31,7%) foram os subtipos mais frequentes. A maioria dos casos apresentou índice de Breslow ≤1mm (70%). Os subtipos mais finos (≤1 mm) foram extensivo superficial e lentigo maligno. Melanomas nodulares possuíam Breslow intermediário (1 a 4 mm) ou espesso (≥4 mm) com altas taxas de disseminação e metástase linfonodal. Conclusão: A frequência manteve-se estável. Houve prevalência em população maior de 60 anos. Os subtipos mais frequentes foram “outros melanomas” e extensivo superficial com localização cefálica e troncular em sua maioria.INCA2020-07-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/91110.32635/2176-9745.RBC.2020v66n3.911Revista Brasileira de Cancerologia; Vol. 66 No. 3 (2020): July/Aug./Sept.; e-03911Revista Brasileira de Cancerologia; Vol. 66 Núm. 3 (2020): jul./agosto/sept.; e-03911Revista Brasileira de Cancerologia; v. 66 n. 3 (2020): jul./ago./set.; e-039112176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporenghttps://rbc.inca.gov.br/index.php/revista/article/view/911/684https://rbc.inca.gov.br/index.php/revista/article/view/911/772Copyright (c) 2020 Revista Brasileira de Cancerologiainfo:eu-repo/semantics/openAccessBarufaldi Bertoldi, MarianaSilva Bastos, Carlos AugustoLabigalini Sampaio, CarolinaHenrique Wroblevski, Eduardo Malta Purim , Kátia Sheylla 2022-03-10T11:56:58Zoai:rbc.inca.gov.br:article/911Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2022-03-10T11:56:58Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Cutaneous Melanoma in a University Hospital, 2001-2016 Melanoma Cutáneo en un Hospital Universitario, 2001-2016 Melanoma Cutâneo em um Hospital Universitário, 2001-2016 |
title |
Cutaneous Melanoma in a University Hospital, 2001-2016 |
spellingShingle |
Cutaneous Melanoma in a University Hospital, 2001-2016 Barufaldi Bertoldi, Mariana Melanoma/epidemiologia Neoplasias Cutâneas/epidemiologia Dermatopatias Melanoma/epidemiology Skin Neoplasms/epidemiology Skin Diseases Melanoma/epidemiología Neoplasias Cutáneas/ epidemiología Enfermedades de la Piel |
title_short |
Cutaneous Melanoma in a University Hospital, 2001-2016 |
title_full |
Cutaneous Melanoma in a University Hospital, 2001-2016 |
title_fullStr |
Cutaneous Melanoma in a University Hospital, 2001-2016 |
title_full_unstemmed |
Cutaneous Melanoma in a University Hospital, 2001-2016 |
title_sort |
Cutaneous Melanoma in a University Hospital, 2001-2016 |
author |
Barufaldi Bertoldi, Mariana |
author_facet |
Barufaldi Bertoldi, Mariana Silva Bastos, Carlos Augusto Labigalini Sampaio, Carolina Henrique Wroblevski, Eduardo Malta Purim , Kátia Sheylla |
author_role |
author |
author2 |
Silva Bastos, Carlos Augusto Labigalini Sampaio, Carolina Henrique Wroblevski, Eduardo Malta Purim , Kátia Sheylla |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Barufaldi Bertoldi, Mariana Silva Bastos, Carlos Augusto Labigalini Sampaio, Carolina Henrique Wroblevski, Eduardo Malta Purim , Kátia Sheylla |
dc.subject.por.fl_str_mv |
Melanoma/epidemiologia Neoplasias Cutâneas/epidemiologia Dermatopatias Melanoma/epidemiology Skin Neoplasms/epidemiology Skin Diseases Melanoma/epidemiología Neoplasias Cutáneas/ epidemiología Enfermedades de la Piel |
topic |
Melanoma/epidemiologia Neoplasias Cutâneas/epidemiologia Dermatopatias Melanoma/epidemiology Skin Neoplasms/epidemiology Skin Diseases Melanoma/epidemiología Neoplasias Cutáneas/ epidemiología Enfermedades de la Piel |
description |
Introduction: Melanoma is the main cause of death among primary skin neoplasms. The worldwide incidence has been increasing, however there is scarce national epidemiological information. Objective: Analyze the epidemiological and histopathological profile of cutaneous melanomas diagnosed at a university hospital in the last 16 years. Method: Historical series of cutaneous melanoma cases from review of charts and histopathological reports from 2001 to 2016. Results: The mean frequency over the years was 2.99 melanomas for every 1,000 new outpatient visits. The casuistry consisted of 224 cases of cutaneous melanomas in 211 patients, Caucasians (98.6%), women (55.9%), with mean age of 57.3 years. The mean time between onset of the lesion (time since the appearance of the lesion or since it began to change reported by the patient) and diagnosis was 4.8 years. The predominant tumor size was 0.5 to 2 cm, affecting the cephalic region in individuals older than 60 years and torso in those younger than 60 years. “Other melanomas” (34.8%) and superficial spreading melanoma (31.7%) were the predominant subtypes. Most of the cases had Breslow index ≤ 1 mm (70% of patients). The thinnest subtypes (≤ 1 mm) were superficial spreading melanoma and lentigo maligna. Nodular melanomas had intermediate Breslow (1 to 4 mm) or thick (≥ 4 mm) with high dissemination rate and lymph node metastasis. Conclusion: The frequency remained stable. Population below 60 years old had a higher prevalence. The most frequent subtypes were “other melanomas” and extensive superficial located mainly in the cephalic and torso regions. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-07-21 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigos, Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/911 10.32635/2176-9745.RBC.2020v66n3.911 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/911 |
identifier_str_mv |
10.32635/2176-9745.RBC.2020v66n3.911 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/911/684 https://rbc.inca.gov.br/index.php/revista/article/view/911/772 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Revista Brasileira de Cancerologia info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Revista Brasileira de Cancerologia |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
INCA |
publisher.none.fl_str_mv |
INCA |
dc.source.none.fl_str_mv |
Revista Brasileira de Cancerologia; Vol. 66 No. 3 (2020): July/Aug./Sept.; e-03911 Revista Brasileira de Cancerologia; Vol. 66 Núm. 3 (2020): jul./agosto/sept.; e-03911 Revista Brasileira de Cancerologia; v. 66 n. 3 (2020): jul./ago./set.; e-03911 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
instname_str |
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
instacron_str |
INCA |
institution |
INCA |
reponame_str |
Revista Brasileira de Cancerologia (Online) |
collection |
Revista Brasileira de Cancerologia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
repository.mail.fl_str_mv |
rbc@inca.gov.br |
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