Breast Cancer in Young Women: Analysis of 12.689 Cases

Detalhes bibliográficos
Autor(a) principal: Barros Pinheiro, Aline
Data de Publicação: 2013
Outros Autores: Scholl Lauter, Dagmar, Coutinho Medeiros, Giselle, Ribeiro Cardozo, Isabella, Mattos Menezes, Letícia, Messias Barreto de Souza, Raysa, Abrahão, Karen, Casado, Letícia, Bergmann, Anke, Santos Thuler, Luiz Claudio
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/500
Resumo: Introduction: Breast cancer in women under 40 years old is unusual. However, in this population the disease usually progresses with worse prognosis. Objectives: To describe the clinical and epidemiological profile of young women diagnosed with breast cancer in Brazil and to compare the clinical characteristics among women aged less than 34 years and those between 35 and 39 years. Method: Cross-sectional study of analytic cases of breast cancer in women aged 18-39 years, enrolled in the Integrator Module of Cancer Hospital Records and Cancer Hospital Registry of the State of São Paulo, from 2000 to 2009. It was performed a descriptive analysis of the variables. Results: There were included 12.689 cases. The median age was 36 years, most of women went to High School (32.3%) and came from the National Health System (74.6%). The advanced stage (≥ IIB) was recorded in 62.8% of cases and at the end of the first treatment, 44.4% of patients had no evidence of disease. Very young women presented more frequently a tumor size > 2 cm, positive lymph node status, metastasis, advanced clinical stages (≥ IIB) and lack of therapeutic response to the first treatment. Conclusion: In Brazil, young women are in advanced stage when they are diagnosed with breast cancer. Those too young (< 35 years) have a more advanced disease stage and poorer response to treatment compared to those aged 35-39.  
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spelling Breast Cancer in Young Women: Analysis of 12.689 CasesCáncer de Mama en Mujeres Jóvenes: Análisis de 12.689 CasosCâncer de Mama em Mulheres Jovens: Análise de 12.689 CasosHumanosAdultoFemininoNeoplasias da Mama-epidemiologiaRegistro HospitalarEstudos TransversaisHumansAdultFemaleBreast Neoplasms-epidemiologyHospital RecordsCross-Sectional StudiesHumanosAdultoFemeninoNeoplasias de la Mama-epidemiologíaRegistro de HospitalaresEstudios TransversalesIntroduction: Breast cancer in women under 40 years old is unusual. However, in this population the disease usually progresses with worse prognosis. Objectives: To describe the clinical and epidemiological profile of young women diagnosed with breast cancer in Brazil and to compare the clinical characteristics among women aged less than 34 years and those between 35 and 39 years. Method: Cross-sectional study of analytic cases of breast cancer in women aged 18-39 years, enrolled in the Integrator Module of Cancer Hospital Records and Cancer Hospital Registry of the State of São Paulo, from 2000 to 2009. It was performed a descriptive analysis of the variables. Results: There were included 12.689 cases. The median age was 36 years, most of women went to High School (32.3%) and came from the National Health System (74.6%). The advanced stage (≥ IIB) was recorded in 62.8% of cases and at the end of the first treatment, 44.4% of patients had no evidence of disease. Very young women presented more frequently a tumor size > 2 cm, positive lymph node status, metastasis, advanced clinical stages (≥ IIB) and lack of therapeutic response to the first treatment. Conclusion: In Brazil, young women are in advanced stage when they are diagnosed with breast cancer. Those too young (< 35 years) have a more advanced disease stage and poorer response to treatment compared to those aged 35-39.  Introducción: El cáncer de mama en mujeres con edad inferior a 40 años no es comun. Pero, en esa población la enfermedad camina, en general, con peor pronóstico. Objetivos: Describir el perfil clínico y epidemiológico de mujeres jóvenes diagnosticadas con cáncer de mama en Brasil y comparar las características clínicas entre mujeres con edad inferior a los 34 años y aquellas entre 35 y 39 años. Método: Estudio transversal de los casos analíticos del cáncer de mama en mujeres entre los 18 y 39 años, inseridos en el Módulo Integrador de los Registros Hospitalarios del Cáncer y en el Registro Hospitalario del Cáncer del Estado de São Paulo, entre los años de 2000 y 2009. Fue realizado el análisis descriptivo de las variables. Resultados: Han sido incluidos 12.689 casos clínicos. El promedio de edad fue de 36 años, la mayoría de las mujeres poseía educación secundaria obligatoria (32,3%) y procedentes del Sistema Nacional de Salud (74,6%). El estadiamiento avanzado (≥ IIB) fue registrado en 62,8% de los casos y, al final del primero tratamiento médico, 44,4% de las pacientes se encuentran sin evidencia de la enfermedad. Mujeres muy jóvenes presentaron con más frecuencia tamano del tumor >2cm, estatus de los ganglios linfáticos positivo, presencia de metastasis, estadiamiento clínico avanzado (≥IIB) y ausencia de respuesta terapéutica al primero tratamiento médico. Conclusión: En Brasil mujeres jóvenes con cáncer de mama presentan estadiamiento avanzado al diagnóstico. Aquellas muy jóvenes (< 35 años) presentan la enfermedad aun más avanzada y peor respuesta terapêutica que aquellas entre 35 y 39 años.Introdução: O câncer de mama em mulheres com idade inferior a 40 anos e incomum. Entretanto, nessa população, a doença cursa, em geral, com pior prognostico. Objetivos: Descrever o perfil clínico e epidemiológico de mulheres jovens diagnosticadas com cancer de mama no Brasil e comparar as características clínicas entre mulheres com idade inferior a 34 anos e aquelas entre 35 e 39 anos. Método: Estudo transversal dos casos analíticos de câncer de mama em mulheres de 18 a 39 anos, inseridos no Módulo Integrador dos Registros Hospitalares de Câncer e no Registro Hospitalar de Câncer do Estado de São Paulo, entre 2000 a 2009. Foi realizada a análise descritiva das variáveis. Resultados: Foram incluídos 12.689 casos. A idade mediana foi de 36 anos, a maioria das mulheres possuía ensino médio (32,3%) e era proveniente do Sistema Único de Saúde (74,6%). O estadiamento avançado (≥IIB) foi registrado em 62,8% dos casos e, ao final do primeiro tratamento, 44,4% das pacientes encontravam-se sem evidencia da doença. Mulheres muito jovens apresentaram mais frequentemente tamanho do tumor >2cm, status dos linfonodos positivo, presença de metástase, estadiamento clínico avançado (≥IIB) e ausência de resposta terapêutica ao primeiro tratamento. Conclusão: No Brasil, mulheres jovens com câncer de mama apresentam estadiamento avançado ao diagnostico. Aquelas muito jovens (<35 anos) apresentam doença ainda mais avançada e pior resposta terapêutica que aquelas entre 35 e 39 anos.INCA2013-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/50010.32635/2176-9745.RBC.2013v59n3.500Revista Brasileira de Cancerologia; Vol. 59 No. 3 (2013): July/Aug./Sept.; 351-359Revista Brasileira de Cancerologia; Vol. 59 Núm. 3 (2013): jul./agosto/sept.; 351-359Revista Brasileira de Cancerologia; v. 59 n. 3 (2013): jul./ago./set. ; 351-3592176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/500/298Barros Pinheiro, Aline Scholl Lauter, DagmarCoutinho Medeiros, Giselle Ribeiro Cardozo, Isabella Mattos Menezes, Letícia Messias Barreto de Souza, Raysa Abrahão, Karen Casado, Letícia Bergmann, AnkeSantos Thuler, Luiz Claudio info:eu-repo/semantics/openAccess2021-11-29T20:11:28Zoai:rbc.inca.gov.br:article/500Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:11:28Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Breast Cancer in Young Women: Analysis of 12.689 Cases
Cáncer de Mama en Mujeres Jóvenes: Análisis de 12.689 Casos
Câncer de Mama em Mulheres Jovens: Análise de 12.689 Casos
title Breast Cancer in Young Women: Analysis of 12.689 Cases
spellingShingle Breast Cancer in Young Women: Analysis of 12.689 Cases
Barros Pinheiro, Aline
Humanos
Adulto
Feminino
Neoplasias da Mama-epidemiologia
Registro Hospitalar
Estudos Transversais
Humans
Adult
Female
Breast Neoplasms-epidemiology
Hospital Records
Cross-Sectional Studies
Humanos
Adulto
Femenino
Neoplasias de la Mama-epidemiología
Registro de Hospitalares
Estudios Transversales
title_short Breast Cancer in Young Women: Analysis of 12.689 Cases
title_full Breast Cancer in Young Women: Analysis of 12.689 Cases
title_fullStr Breast Cancer in Young Women: Analysis of 12.689 Cases
title_full_unstemmed Breast Cancer in Young Women: Analysis of 12.689 Cases
title_sort Breast Cancer in Young Women: Analysis of 12.689 Cases
author Barros Pinheiro, Aline
author_facet Barros Pinheiro, Aline
Scholl Lauter, Dagmar
Coutinho Medeiros, Giselle
Ribeiro Cardozo, Isabella
Mattos Menezes, Letícia
Messias Barreto de Souza, Raysa
Abrahão, Karen
Casado, Letícia
Bergmann, Anke
Santos Thuler, Luiz Claudio
author_role author
author2 Scholl Lauter, Dagmar
Coutinho Medeiros, Giselle
Ribeiro Cardozo, Isabella
Mattos Menezes, Letícia
Messias Barreto de Souza, Raysa
Abrahão, Karen
Casado, Letícia
Bergmann, Anke
Santos Thuler, Luiz Claudio
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Barros Pinheiro, Aline
Scholl Lauter, Dagmar
Coutinho Medeiros, Giselle
Ribeiro Cardozo, Isabella
Mattos Menezes, Letícia
Messias Barreto de Souza, Raysa
Abrahão, Karen
Casado, Letícia
Bergmann, Anke
Santos Thuler, Luiz Claudio
dc.subject.por.fl_str_mv Humanos
Adulto
Feminino
Neoplasias da Mama-epidemiologia
Registro Hospitalar
Estudos Transversais
Humans
Adult
Female
Breast Neoplasms-epidemiology
Hospital Records
Cross-Sectional Studies
Humanos
Adulto
Femenino
Neoplasias de la Mama-epidemiología
Registro de Hospitalares
Estudios Transversales
topic Humanos
Adulto
Feminino
Neoplasias da Mama-epidemiologia
Registro Hospitalar
Estudos Transversais
Humans
Adult
Female
Breast Neoplasms-epidemiology
Hospital Records
Cross-Sectional Studies
Humanos
Adulto
Femenino
Neoplasias de la Mama-epidemiología
Registro de Hospitalares
Estudios Transversales
description Introduction: Breast cancer in women under 40 years old is unusual. However, in this population the disease usually progresses with worse prognosis. Objectives: To describe the clinical and epidemiological profile of young women diagnosed with breast cancer in Brazil and to compare the clinical characteristics among women aged less than 34 years and those between 35 and 39 years. Method: Cross-sectional study of analytic cases of breast cancer in women aged 18-39 years, enrolled in the Integrator Module of Cancer Hospital Records and Cancer Hospital Registry of the State of São Paulo, from 2000 to 2009. It was performed a descriptive analysis of the variables. Results: There were included 12.689 cases. The median age was 36 years, most of women went to High School (32.3%) and came from the National Health System (74.6%). The advanced stage (≥ IIB) was recorded in 62.8% of cases and at the end of the first treatment, 44.4% of patients had no evidence of disease. Very young women presented more frequently a tumor size > 2 cm, positive lymph node status, metastasis, advanced clinical stages (≥ IIB) and lack of therapeutic response to the first treatment. Conclusion: In Brazil, young women are in advanced stage when they are diagnosed with breast cancer. Those too young (< 35 years) have a more advanced disease stage and poorer response to treatment compared to those aged 35-39.  
publishDate 2013
dc.date.none.fl_str_mv 2013-09-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/500
10.32635/2176-9745.RBC.2013v59n3.500
url https://rbc.inca.gov.br/index.php/revista/article/view/500
identifier_str_mv 10.32635/2176-9745.RBC.2013v59n3.500
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/500/298
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 59 No. 3 (2013): July/Aug./Sept.; 351-359
Revista Brasileira de Cancerologia; Vol. 59 Núm. 3 (2013): jul./agosto/sept.; 351-359
Revista Brasileira de Cancerologia; v. 59 n. 3 (2013): jul./ago./set. ; 351-359
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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