Prevalence of Cancer Cachexia and its Associated Factors in Home Care

Detalhes bibliográficos
Autor(a) principal: Duval, Patrícia Abrantes
Data de Publicação: 2015
Outros Autores: Bergmann, Rafaela Bülow, Vale, Idrejane Aparecida Viccari do, Colling, Catiússa, Araújo, Évelyn de Souza, Assunção, Maria Cecília Formoso
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/262
Resumo: Introduction: Early identification of the factors triggering cancer cachexia is important for the nutritional intervention to assist in its prevention. Objective: To determine which factors are associated with cachexia in cancer patients participating in a home care program, using standard concepts for the syndrome. Method: A descriptive cross-sectional study using secondary data from medical records of all patients attended by the Nutrition Service staff from February 2010 to February 2014. The presence of cachexia was analyzed in relation to gender, age, tumor location, stage of disease, presence of metastases, type of anti-cancer treatment and symptoms presented. Results: There were 276 patients, mean age 61.5±13.7 years, predominance of male gender (57.3%), advanced disease (90%) and metastasis (78.6%). The prevalence of cachexia was 75.3%, and it was associated with disease stage (p=0.001), the presence of metastases (p=0.002) and tumor location (p=0.002), and it was more common among patients with gastrointestinal tumors (37.3%). There was an association between cachexia and anorexia (p<0.001), early satiety (p<0.001), constipation (p=0.02), mucositis (p=0.02), nausea (p=0.03), vomiting (p=0.01), dysgeusia (p=0.01), dysosmia (p=0.01) and pain (p=0.01). Conclusion: In addition to the factors directly related to the disease, such as tumor location, stage and metastasis, several symptoms were associated with cachexia, and they deserve special attention during nutritional interventions. Other studies assessing symptoms associated with cachexia are needed so that they can compare results and establish a nutritional intervention.
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spelling Prevalence of Cancer Cachexia and its Associated Factors in Home CarePrevalencia de la Caquexia Neoplástica y sus Factores Asociados en la Atención DomiciliariaPrevalência de Caquexia Neoplásica e Fatores Associados na Internação DomiciliarCaquexiaNeoplasiasServiços de Assistência Domiciliar;Cuidados PaliativosCachexiaNeoplasmsHome Care ServicesPalliative CareCaquexiaNeoplasiasServicios de Atención de Salud a DomicilioCuidados PaliativosIntroduction: Early identification of the factors triggering cancer cachexia is important for the nutritional intervention to assist in its prevention. Objective: To determine which factors are associated with cachexia in cancer patients participating in a home care program, using standard concepts for the syndrome. Method: A descriptive cross-sectional study using secondary data from medical records of all patients attended by the Nutrition Service staff from February 2010 to February 2014. The presence of cachexia was analyzed in relation to gender, age, tumor location, stage of disease, presence of metastases, type of anti-cancer treatment and symptoms presented. Results: There were 276 patients, mean age 61.5±13.7 years, predominance of male gender (57.3%), advanced disease (90%) and metastasis (78.6%). The prevalence of cachexia was 75.3%, and it was associated with disease stage (p=0.001), the presence of metastases (p=0.002) and tumor location (p=0.002), and it was more common among patients with gastrointestinal tumors (37.3%). There was an association between cachexia and anorexia (p<0.001), early satiety (p<0.001), constipation (p=0.02), mucositis (p=0.02), nausea (p=0.03), vomiting (p=0.01), dysgeusia (p=0.01), dysosmia (p=0.01) and pain (p=0.01). Conclusion: In addition to the factors directly related to the disease, such as tumor location, stage and metastasis, several symptoms were associated with cachexia, and they deserve special attention during nutritional interventions. Other studies assessing symptoms associated with cachexia are needed so that they can compare results and establish a nutritional intervention.Introducción: La identificación temprana de los factores desencadenantes de la caquexia oncológica es importante para intervención nutricional para para ayudar en su prevención. Objetivo: Determinar qué factores se asocian con la caquexia en pacientes con cáncer que participaban en un programa de atención a domicilio, utilizando conceptos estándar para el síndrome. Método: Estudio descriptivo transversal utilizando datos secundarios de las historias clínicas de todos los pacientes tratados por el Servicio de la Nutrición febrero del 2010 hasta febrero del 2014. La caquexia se analizó en relación con el sexo, edad, localización del tumor, estadio de la enfermedad, presencia de metástasis, tipo del tratamiento y síntomas presentados. Resultados: Fueron 276 pacientes, con media de edad de 61,5±13,7 años, predominio del sexo masculino (57,3%), enfermedad avanzada (90%) y metástasis (78,6%). La prevalencia de caquexia fue del 75,3%, siendo asociada con estadio del enfermedad (p=0,001), presencia de metástasis (p=0,002) y estadio del tumor (p=0,002), y fue más común entre pacientes con tumores gastrointestinales (37,3%). Se observó anorexia asociada con la caquexia (p<0,001), saciedad temprana (p<0,001), estreñimiento (p=0,02), mucositis (p=0,02), náuseas (p=0,03), vómitos (p=0,01), disgeusia (p=0,01), disosmia (p=0,01) y el dolor (p=0,01). Conclusión: Además de los factores directamente relacionados con la enfermedad, tales como estadio y metástasis, varios síntomas se asociaron con caquexia, y merecen una atención especial durante las intervenciones nutricionales. Se necesitan otros estudios de evaluación de los síntomas asociados con la caquexia, para que se puedan comparar los resultados y establecer una intervención nutricional.Introdução: A identificação precoce dos fatores desencadeantes da caquexia oncológica é importante para que a intervenção nutricional auxilie na sua prevenção. Objetivo: Verificar quais são os fatores associados à caquexia em pacientes oncológicos participantes de um programa de internação domiciliar, utilizando conceitos padronizados para a síndrome. Método: Estudo transversal descritivo a partir de dados secundários dos prontuários de todos os pacientes atendidos pelo Serviço de Nutrição, entre fevereiro de 2010 a fevereiro de 2014. A presença de caquexia foi analisada em relação ao sexo, idade, localização do tumor, estadiamento da doença, presença de metástases, tipo de tratamento antineoplásico e sintomas apresentados. Resultados: Foram analisados 276 pacientes, com média de idade de 61,5+13,7 anos, predomínio do sexo masculino (57,3%), doença avançada (90%) e presença de metástases (78,6%). A prevalência de caquexia foi de 75,3%, estando associada ao estadiamento da doença (p=0,001), à presença de metástases (p=0,002) e à localização do tumor (p=0,002), sendo mais comum entre os portadores de tumores gastrointestinais (37,3%). Observou-se associação da caquexia com anorexia (p<0,001), saciedade precoce (p<0,001), constipação (p=0,02), mucosite (p=0,02), náuseas (p=0,03), vômitos (p=0,01), disgeusia (p=0,01), disosmia (p=0,01) e dor (p=0,01). Conclusão: Além dos fatores diretamente relacionados com a doença, tais como: localização do tumor, estadiamento e presença de metástases, diversos sintomas associaram-se à caquexia, e esses merecem atenção diferenciada durante as intervenções nutricionais. Outros estudos, que avaliem os sintomas associados à caquexia, são necessários para que se possam comparar resultados e estabelecer uma intervenção nutricional.INCA2015-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/26210.32635/2176-9745.RBC.2015v61n3.262Revista Brasileira de Cancerologia; Vol. 61 No. 3 (2015): July/Aug./Sept.; 261-267Revista Brasileira de Cancerologia; Vol. 61 Núm. 3 (2015): jul./agosto/sept.; 261-267Revista Brasileira de Cancerologia; v. 61 n. 3 (2015): jul./ago./set.; 261-2672176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/262/173Duval, Patrícia AbrantesBergmann, Rafaela BülowVale, Idrejane Aparecida Viccari doColling, CatiússaAraújo, Évelyn de SouzaAssunção, Maria Cecília Formosoinfo:eu-repo/semantics/openAccess2021-11-29T20:08:29Zoai:rbc.inca.gov.br:article/262Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:08:29Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Prevalence of Cancer Cachexia and its Associated Factors in Home Care
Prevalencia de la Caquexia Neoplástica y sus Factores Asociados en la Atención Domiciliaria
Prevalência de Caquexia Neoplásica e Fatores Associados na Internação Domiciliar
title Prevalence of Cancer Cachexia and its Associated Factors in Home Care
spellingShingle Prevalence of Cancer Cachexia and its Associated Factors in Home Care
Duval, Patrícia Abrantes
Caquexia
Neoplasias
Serviços de Assistência Domiciliar;
Cuidados Paliativos
Cachexia
Neoplasms
Home Care Services
Palliative Care
Caquexia
Neoplasias
Servicios de Atención de Salud a Domicilio
Cuidados Paliativos
title_short Prevalence of Cancer Cachexia and its Associated Factors in Home Care
title_full Prevalence of Cancer Cachexia and its Associated Factors in Home Care
title_fullStr Prevalence of Cancer Cachexia and its Associated Factors in Home Care
title_full_unstemmed Prevalence of Cancer Cachexia and its Associated Factors in Home Care
title_sort Prevalence of Cancer Cachexia and its Associated Factors in Home Care
author Duval, Patrícia Abrantes
author_facet Duval, Patrícia Abrantes
Bergmann, Rafaela Bülow
Vale, Idrejane Aparecida Viccari do
Colling, Catiússa
Araújo, Évelyn de Souza
Assunção, Maria Cecília Formoso
author_role author
author2 Bergmann, Rafaela Bülow
Vale, Idrejane Aparecida Viccari do
Colling, Catiússa
Araújo, Évelyn de Souza
Assunção, Maria Cecília Formoso
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Duval, Patrícia Abrantes
Bergmann, Rafaela Bülow
Vale, Idrejane Aparecida Viccari do
Colling, Catiússa
Araújo, Évelyn de Souza
Assunção, Maria Cecília Formoso
dc.subject.por.fl_str_mv Caquexia
Neoplasias
Serviços de Assistência Domiciliar;
Cuidados Paliativos
Cachexia
Neoplasms
Home Care Services
Palliative Care
Caquexia
Neoplasias
Servicios de Atención de Salud a Domicilio
Cuidados Paliativos
topic Caquexia
Neoplasias
Serviços de Assistência Domiciliar;
Cuidados Paliativos
Cachexia
Neoplasms
Home Care Services
Palliative Care
Caquexia
Neoplasias
Servicios de Atención de Salud a Domicilio
Cuidados Paliativos
description Introduction: Early identification of the factors triggering cancer cachexia is important for the nutritional intervention to assist in its prevention. Objective: To determine which factors are associated with cachexia in cancer patients participating in a home care program, using standard concepts for the syndrome. Method: A descriptive cross-sectional study using secondary data from medical records of all patients attended by the Nutrition Service staff from February 2010 to February 2014. The presence of cachexia was analyzed in relation to gender, age, tumor location, stage of disease, presence of metastases, type of anti-cancer treatment and symptoms presented. Results: There were 276 patients, mean age 61.5±13.7 years, predominance of male gender (57.3%), advanced disease (90%) and metastasis (78.6%). The prevalence of cachexia was 75.3%, and it was associated with disease stage (p=0.001), the presence of metastases (p=0.002) and tumor location (p=0.002), and it was more common among patients with gastrointestinal tumors (37.3%). There was an association between cachexia and anorexia (p<0.001), early satiety (p<0.001), constipation (p=0.02), mucositis (p=0.02), nausea (p=0.03), vomiting (p=0.01), dysgeusia (p=0.01), dysosmia (p=0.01) and pain (p=0.01). Conclusion: In addition to the factors directly related to the disease, such as tumor location, stage and metastasis, several symptoms were associated with cachexia, and they deserve special attention during nutritional interventions. Other studies assessing symptoms associated with cachexia are needed so that they can compare results and establish a nutritional intervention.
publishDate 2015
dc.date.none.fl_str_mv 2015-09-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/262
10.32635/2176-9745.RBC.2015v61n3.262
url https://rbc.inca.gov.br/index.php/revista/article/view/262
identifier_str_mv 10.32635/2176-9745.RBC.2015v61n3.262
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/262/173
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 61 No. 3 (2015): July/Aug./Sept.; 261-267
Revista Brasileira de Cancerologia; Vol. 61 Núm. 3 (2015): jul./agosto/sept.; 261-267
Revista Brasileira de Cancerologia; v. 61 n. 3 (2015): jul./ago./set.; 261-267
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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