Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/1775 |
Resumo: | Local recurrence following mastectomy or wide local excision of malignant breast disease is reported as ranging from 5 to 40% and is usually detected at clinical screening. There are few reports in the literature in which microscopic recurrence has been identified in mastectomy scars in the absence of clinical suspicion. We assessed the importance of routine mastectomy scar histology at the time of breast reconstruction for detecting microscopic recurrence and the impact of early diagnosis on patient survival. In a retrospective series of 261 asymptomatic patients, we found no evidence of malignancy or microscopic recurrence in any of the scars examined. Many oncology services recommend that all mastectomy scars be submitted to histological examination at the time of breast reconstruction. However, our results suggest that this routine exam may not be necessary. We believe that histological examination of mastectomy scars in late breast reconstruction in patients with comprehensive clinical examination and mammography may provide no additional benefit in the oncologic follow-up of these patients. |
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Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?Exame Histopatológico das Cicatrizes de Mastectomia nas Reconstruções Tardias de Mama: Existe Relevância Oncológica?Reconstrução mamáriaCâncer de mamaCicatrizMastectomiaRecidiva local de neoplasiaBreast reconstructionBreast cancerScarMastectomyRecurrenceLocal recurrence following mastectomy or wide local excision of malignant breast disease is reported as ranging from 5 to 40% and is usually detected at clinical screening. There are few reports in the literature in which microscopic recurrence has been identified in mastectomy scars in the absence of clinical suspicion. We assessed the importance of routine mastectomy scar histology at the time of breast reconstruction for detecting microscopic recurrence and the impact of early diagnosis on patient survival. In a retrospective series of 261 asymptomatic patients, we found no evidence of malignancy or microscopic recurrence in any of the scars examined. Many oncology services recommend that all mastectomy scars be submitted to histological examination at the time of breast reconstruction. However, our results suggest that this routine exam may not be necessary. We believe that histological examination of mastectomy scars in late breast reconstruction in patients with comprehensive clinical examination and mammography may provide no additional benefit in the oncologic follow-up of these patients.A recorrência local, pós-mastectomia, para doença mamária maligna varia entre 5% e 40%, sendo usualmente detectada ao exame clínico. Os relatos da literatura mostram que as recorrências microscópicas identificadas em cicatrizes de mastectomia, sem suspeita clínica, são raras. Sendo assim, este trabalho avalia a importância da análise histopatológica de rotina das cicatrizes de mastectomia no momento da reconstrução de mama, de maneira a detectar a freqüência de recorrência microscópica e o impacto do diagnóstico precoce na sobrevida das pacientes. Em uma série retrospectiva de 261 pacientes assintomáticas, não foi encontrada evidência de malignidade ou recorrência microscópica em nenhuma das cicatrizes avaliadas. Em muitos serviços, é recomendado que todas as cicatrizes de mastectomia sejam submetidas à análise histopatológica na época da reconstrução. Contudo, este estudo sugere não ser necessário este exame de rotina. Os resultados indicam que o exame histopatológico das cicatrizes de mastectomia em pacientes submetidas à reconstrução tardia de mama e em pacientes avaliadas por exame clínico detalhado e a avaliação mamográfica podem não trazer maiores benefícios ao seguimento oncológico dessas pacientes, contudo estudos complementares são necessários.INCA2007-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/177510.32635/2176-9745.RBC.2007v53n4.1775Revista Brasileira de Cancerologia; Vol. 53 No. 4 (2007): Oct./Nov./Dec.; 421-424Revista Brasileira de Cancerologia; Vol. 53 Núm. 4 (2007): oct./nov./dic.; 421-424Revista Brasileira de Cancerologia; v. 53 n. 4 (2007): out./nov./dez.; 421-4242176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/1775/1065Gregorio, Telma Carolina Ritter deSbalchiero, Juliano Carlos Leal, Paulo Roberto de Albuquerque info:eu-repo/semantics/openAccess2021-11-29T20:24:54Zoai:rbc.inca.gov.br:article/1775Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:24:54Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance? Exame Histopatológico das Cicatrizes de Mastectomia nas Reconstruções Tardias de Mama: Existe Relevância Oncológica? |
title |
Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance? |
spellingShingle |
Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance? Gregorio, Telma Carolina Ritter de Reconstrução mamária Câncer de mama Cicatriz Mastectomia Recidiva local de neoplasia Breast reconstruction Breast cancer Scar Mastectomy Recurrence |
title_short |
Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance? |
title_full |
Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance? |
title_fullStr |
Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance? |
title_full_unstemmed |
Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance? |
title_sort |
Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance? |
author |
Gregorio, Telma Carolina Ritter de |
author_facet |
Gregorio, Telma Carolina Ritter de Sbalchiero, Juliano Carlos Leal, Paulo Roberto de Albuquerque |
author_role |
author |
author2 |
Sbalchiero, Juliano Carlos Leal, Paulo Roberto de Albuquerque |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Gregorio, Telma Carolina Ritter de Sbalchiero, Juliano Carlos Leal, Paulo Roberto de Albuquerque |
dc.subject.por.fl_str_mv |
Reconstrução mamária Câncer de mama Cicatriz Mastectomia Recidiva local de neoplasia Breast reconstruction Breast cancer Scar Mastectomy Recurrence |
topic |
Reconstrução mamária Câncer de mama Cicatriz Mastectomia Recidiva local de neoplasia Breast reconstruction Breast cancer Scar Mastectomy Recurrence |
description |
Local recurrence following mastectomy or wide local excision of malignant breast disease is reported as ranging from 5 to 40% and is usually detected at clinical screening. There are few reports in the literature in which microscopic recurrence has been identified in mastectomy scars in the absence of clinical suspicion. We assessed the importance of routine mastectomy scar histology at the time of breast reconstruction for detecting microscopic recurrence and the impact of early diagnosis on patient survival. In a retrospective series of 261 asymptomatic patients, we found no evidence of malignancy or microscopic recurrence in any of the scars examined. Many oncology services recommend that all mastectomy scars be submitted to histological examination at the time of breast reconstruction. However, our results suggest that this routine exam may not be necessary. We believe that histological examination of mastectomy scars in late breast reconstruction in patients with comprehensive clinical examination and mammography may provide no additional benefit in the oncologic follow-up of these patients. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-12-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigos, Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/1775 10.32635/2176-9745.RBC.2007v53n4.1775 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/1775 |
identifier_str_mv |
10.32635/2176-9745.RBC.2007v53n4.1775 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/1775/1065 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
INCA |
publisher.none.fl_str_mv |
INCA |
dc.source.none.fl_str_mv |
Revista Brasileira de Cancerologia; Vol. 53 No. 4 (2007): Oct./Nov./Dec.; 421-424 Revista Brasileira de Cancerologia; Vol. 53 Núm. 4 (2007): oct./nov./dic.; 421-424 Revista Brasileira de Cancerologia; v. 53 n. 4 (2007): out./nov./dez.; 421-424 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
instname_str |
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
instacron_str |
INCA |
institution |
INCA |
reponame_str |
Revista Brasileira de Cancerologia (Online) |
collection |
Revista Brasileira de Cancerologia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
repository.mail.fl_str_mv |
rbc@inca.gov.br |
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1797042248083308544 |