Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?

Detalhes bibliográficos
Autor(a) principal: Gregorio, Telma Carolina Ritter de
Data de Publicação: 2007
Outros Autores: Sbalchiero, Juliano Carlos, Leal, Paulo Roberto de Albuquerque
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/1775
Resumo: Local recurrence following mastectomy or wide local excision of malignant breast disease is reported as ranging from 5 to 40% and is usually detected at clinical screening. There are few reports in the literature in which microscopic recurrence has been identified in mastectomy scars in the absence of clinical suspicion. We assessed the importance of routine mastectomy scar histology at the time of breast reconstruction for detecting microscopic recurrence and the impact of early diagnosis on patient survival. In a retrospective series of 261 asymptomatic patients, we found no evidence of malignancy or microscopic recurrence in any of the scars examined. Many oncology services recommend that all mastectomy scars be submitted to histological examination at the time of breast reconstruction. However, our results suggest that this routine exam may not be necessary. We believe that histological examination of mastectomy scars in late breast reconstruction in patients with comprehensive clinical examination and mammography may provide no additional benefit in the oncologic follow-up of these patients.
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spelling Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?Exame Histopatológico das Cicatrizes de Mastectomia nas Reconstruções Tardias de Mama: Existe Relevância Oncológica?Reconstrução mamáriaCâncer de mamaCicatrizMastectomiaRecidiva local de neoplasiaBreast reconstructionBreast cancerScarMastectomyRecurrenceLocal recurrence following mastectomy or wide local excision of malignant breast disease is reported as ranging from 5 to 40% and is usually detected at clinical screening. There are few reports in the literature in which microscopic recurrence has been identified in mastectomy scars in the absence of clinical suspicion. We assessed the importance of routine mastectomy scar histology at the time of breast reconstruction for detecting microscopic recurrence and the impact of early diagnosis on patient survival. In a retrospective series of 261 asymptomatic patients, we found no evidence of malignancy or microscopic recurrence in any of the scars examined. Many oncology services recommend that all mastectomy scars be submitted to histological examination at the time of breast reconstruction. However, our results suggest that this routine exam may not be necessary. We believe that histological examination of mastectomy scars in late breast reconstruction in patients with comprehensive clinical examination and mammography may provide no additional benefit in the oncologic follow-up of these patients.A recorrência local, pós-mastectomia, para doença mamária maligna varia entre 5% e 40%, sendo usualmente detectada ao exame clínico. Os relatos da literatura mostram que as recorrências microscópicas identificadas em cicatrizes de mastectomia, sem suspeita clínica, são raras. Sendo assim, este trabalho avalia a importância da análise histopatológica de rotina das cicatrizes de mastectomia no momento da reconstrução de mama, de maneira a detectar a freqüência de recorrência microscópica e o impacto do diagnóstico precoce na sobrevida das pacientes. Em uma série retrospectiva de 261 pacientes assintomáticas, não foi encontrada evidência de malignidade ou recorrência microscópica em nenhuma das cicatrizes avaliadas. Em muitos serviços, é recomendado que todas as cicatrizes de mastectomia sejam submetidas à análise histopatológica na época da reconstrução. Contudo, este estudo sugere não ser necessário este exame de rotina. Os resultados indicam que o exame histopatológico das cicatrizes de mastectomia em pacientes submetidas à reconstrução tardia de mama e em pacientes avaliadas por exame clínico detalhado e a avaliação mamográfica podem não trazer maiores benefícios ao seguimento oncológico dessas pacientes, contudo estudos complementares são necessários.INCA2007-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/177510.32635/2176-9745.RBC.2007v53n4.1775Revista Brasileira de Cancerologia; Vol. 53 No. 4 (2007): Oct./Nov./Dec.; 421-424Revista Brasileira de Cancerologia; Vol. 53 Núm. 4 (2007): oct./nov./dic.; 421-424Revista Brasileira de Cancerologia; v. 53 n. 4 (2007): out./nov./dez.; 421-4242176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/1775/1065Gregorio, Telma Carolina Ritter deSbalchiero, Juliano Carlos Leal, Paulo Roberto de Albuquerque info:eu-repo/semantics/openAccess2021-11-29T20:24:54Zoai:rbc.inca.gov.br:article/1775Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:24:54Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?
Exame Histopatológico das Cicatrizes de Mastectomia nas Reconstruções Tardias de Mama: Existe Relevância Oncológica?
title Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?
spellingShingle Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?
Gregorio, Telma Carolina Ritter de
Reconstrução mamária
Câncer de mama
Cicatriz
Mastectomia
Recidiva local de neoplasia
Breast reconstruction
Breast cancer
Scar
Mastectomy
Recurrence
title_short Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?
title_full Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?
title_fullStr Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?
title_full_unstemmed Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?
title_sort Histopathological Analysis of Mastectomy Scars in Delayed Breast Reconstruction: is There Any Oncologic Relevance?
author Gregorio, Telma Carolina Ritter de
author_facet Gregorio, Telma Carolina Ritter de
Sbalchiero, Juliano Carlos
Leal, Paulo Roberto de Albuquerque
author_role author
author2 Sbalchiero, Juliano Carlos
Leal, Paulo Roberto de Albuquerque
author2_role author
author
dc.contributor.author.fl_str_mv Gregorio, Telma Carolina Ritter de
Sbalchiero, Juliano Carlos
Leal, Paulo Roberto de Albuquerque
dc.subject.por.fl_str_mv Reconstrução mamária
Câncer de mama
Cicatriz
Mastectomia
Recidiva local de neoplasia
Breast reconstruction
Breast cancer
Scar
Mastectomy
Recurrence
topic Reconstrução mamária
Câncer de mama
Cicatriz
Mastectomia
Recidiva local de neoplasia
Breast reconstruction
Breast cancer
Scar
Mastectomy
Recurrence
description Local recurrence following mastectomy or wide local excision of malignant breast disease is reported as ranging from 5 to 40% and is usually detected at clinical screening. There are few reports in the literature in which microscopic recurrence has been identified in mastectomy scars in the absence of clinical suspicion. We assessed the importance of routine mastectomy scar histology at the time of breast reconstruction for detecting microscopic recurrence and the impact of early diagnosis on patient survival. In a retrospective series of 261 asymptomatic patients, we found no evidence of malignancy or microscopic recurrence in any of the scars examined. Many oncology services recommend that all mastectomy scars be submitted to histological examination at the time of breast reconstruction. However, our results suggest that this routine exam may not be necessary. We believe that histological examination of mastectomy scars in late breast reconstruction in patients with comprehensive clinical examination and mammography may provide no additional benefit in the oncologic follow-up of these patients.
publishDate 2007
dc.date.none.fl_str_mv 2007-12-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1775
10.32635/2176-9745.RBC.2007v53n4.1775
url https://rbc.inca.gov.br/index.php/revista/article/view/1775
identifier_str_mv 10.32635/2176-9745.RBC.2007v53n4.1775
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1775/1065
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 53 No. 4 (2007): Oct./Nov./Dec.; 421-424
Revista Brasileira de Cancerologia; Vol. 53 Núm. 4 (2007): oct./nov./dic.; 421-424
Revista Brasileira de Cancerologia; v. 53 n. 4 (2007): out./nov./dez.; 421-424
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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