Swine and poultry pathogens: The complete genome sequences of two strains of Mycoplasma hyopneumoniae and a strain of Mycoplasma synoviae

• Autor(a) principal: Vasconcelos, Ana Tereza
• Data de Publicação: 2005
• Outros Autores: Ferreira, Henrique Bunselmeyer, Bizarro, Cristiano Valim, Bonatto, Sandro L., Carvalho, Marcos O., Pinto, Paulo Marcos, Almeida, Darcy F., Almeida, Luiz G.P., Almeida, Rosana de, Alves-Filho, Leonardo, Assunção, Enedina Nogueira, Azevedo, Vasco Ariston Carvalho, Bogo, Maurício Reis, Brígido, Marcelo Macedo, Brocchi, Marcelo, Burity, Hélio Almeida, Camargo, Anamaria A., Silva Camargo, Sandro da, Carepo, Marta S.P., Carraro, Dirce Maria, Mattos Cascardo, Júlio Cézar de, Castro, Luiza Amaral de, Cavalcanti, Gisele, Chemale, Gustavo, Collevatti, Rosane Garcia, Cunha, Cristina W., Dallagiovanna, Bruno, Dambrós, Bibiana Paula, Dellagostin, Odir Antônio, Falcão, Clarissa Lima, Fantinatti-Garboggini, Fabiana, Felipe, Maria Sueli Soares, Fiorentin, Laurimar, Franco, Glória Regina, Freitas, Nara S A, FrÃ\xadas, Diego, Grangeiro, Thalles Barbosa, Grisard, Edmundo Carlos, Guimarães, Cláudia Teixeira, Hungría, Mariangela, Jardim, Sílvia Neto, Krieger, Marco Aurélio, Laurino, Jomar Pereira, Agnez-Lima, Lucymara Fassarella, Lopes, Maryellen I., Loreto, Elgion Lúcio da Silva, Madeira, Humberto Maciel França, Manfio, Gilson Paulo, Queiroz Maranhão, Andrea, Martinkovics, Christyanne T., Batistuzzo de Medeiros, Sìlvia Regina, Moreira, Miguel Ångelo Martins, Neiva, Márcia, Ramalho-Neto, Cícero Eduardo, Nicolás, Marisa Fabiana, Oliveira, Sérgio Costa F., Paixão, Roger Ferreira Cury, Pedrosa, Fabio O., Pena, Sergio Danilo Junho, Pereira, Maristela, Pereira-Ferrari, Lílian, Piffer, Itamar Antônio, Pinto, Luciano Silva da, Potrich, Deise Porto, Salim, Anna Christina Matos, Santos, Fabrício Rodrigues dos, Schmitt, Renata, Schneider, Maria Paula Cruz, Schrank, Augusto, Schrank, Irene Silveira, Schuck, Adriana F., Seuánez, Héctor Nicolás, Silva, Denise Wanderlei, Silva, Rosane A., Silva, Sérgio Ceroni da, Almeida Soares, Célia Maria A. de, Souza, Kelly R.L., Souza, Rangel Celso, Staats, Charley Christian, Steffens, Maria Berenice Reynaud, Teixeira, Santuza Ribeiro, Ürményi, Turán Péter, Vainstein, Marilene Henning, Zuccherato, Luciana Werneck, Simpson, Andrew John George, Zaha, Arnaldo
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional do INPA
• Texto Completo: https://repositorio.inpa.gov.br/handle/1/16384
• topic: Adhesin; Genome, Bacterial; Dna Sequence; Gene Rearrangement; Gene Sequence; Genome Size; Metabolism; Mycoplasma Gallisepticum; Mycoplasma Hyopneumoniae; Mycoplasma Synoviae; Nonhuman; Nucleotide Sequence; Pathogenesis; Pathogenicity; Poultry; Priority Journal; Strain Difference; Swine; Animal; Evolution, Molecular; Gene Rearrangement; Gene Transfer, Horizontal; Genome, Bacterial; Genomics; Molecular Sequence Data; Mycoplasma Hyopneumoniae; Mycoplasma Infections; Mycoplasma Synoviae; Phylogeny; Pneumonia Of Swine, Mycoplasmal; Poultry; Poultry Diseases; Swine; Aves; Mycoplasma; Mycoplasma Gallisepticum; Mycoplasma Hyopneumoniae; Mycoplasma Synoviae; Sus Scrofa

This work reports the results of analyses of three complete mycoplasma genomes, a pathogenic (7448) and a nonpathogenic (J) strain of the swine pathogen Mycoplasma hyopneumoniae and a strain of the avian pathogen Mycoplasma synoviae; the genome sizes of the three strains were 920,079 bp, 897,405 bp, and 799,476 bp, respectively. These genomes were compared with other sequenced mycoplasma genomes reported in the literature to examine several aspects of mycoplasma evolution. Strain-specific regions, including integrative and conjugal elements, and genome rearrangements and alterations in adhesin sequences were observed in the M. hyopneumoniae strains, and all of these were potentially related to pathogenicity. Genomic comparisons revealed that reduction in genome size implied loss of redundant metabolic pathways, with maintenance of alternative routes in different species. Horizontal gene transfer was consistently observed between M. synoviae and Mycoplasma gallisepticum. Our analyses indicated a likely transfer event of hemagglutinin-coding DNA sequences from M. gallisepticum to M. synoviae. Copyright © 2005, American Society for Microbiology. All Rights Reserved.