Plants of the annonaceae traditionally used as antimalarials: A review
Main Author: | |
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Publication Date: | 2014 |
Other Authors: | , , , |
Format: | Article |
Language: | por |
Source: | Repositório Institucional do INPA |
Download full: | https://repositorio.inpa.gov.br/handle/1/16017 |
Summary: | Species of the Annonaceae family are used all over the tropics in traditional medicine in tropical regions for the treatment of malaria and other illnesses. Phytochemical studies of this family have revealed chemical components which could offer new alternatives for the treatment and control of malaria. Searches in scientific reference sites (SciFinder Scholar, Scielo, PubMed, ScienceDirect and ISI Web of Science) and a bibliographic literature search for species of Annonaceae used traditionally to treat malaria and fever were carried out. This family contains 2,100 species in 123 genera. We encountered 113 articles reporting medicinal use of one or more species of this family including 63 species in 27 genera with uses as antimalarials and febrifuges. Even though the same species of Annonaceae are used by diverse ethnic groups, different plant parts are often chosen for applications, and diverse methods of preparation and treatment are used. The ethanol extracts of Polyalthia debilis and Xylopia aromatica proved to be quite active against Plasmodium falciparum in vitro (median inhibition concentration, ICinf50/inf < 1.5 μg/mL). Intraperitoneal injection of Annickia chlorantha aqueous extracts (cited as Enantia chlorantha) cleared chloroquine-resistant Plasmodium yoelii nigeriensis from the blood of mice in a dose-dependant manner. More phytochemical profiles of Annonaceous species are required; especially information on the more commonly distributed antimalarial compounds in this family. |
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Frausin, GinaLima, Renata Braga SouzaHidalgo, Ari de FreitasMaas, Paul J.M.Pohlit, Adrian Martin2020-05-21T21:56:30Z2020-05-21T21:56:30Z2014https://repositorio.inpa.gov.br/handle/1/1601710.1590/S0100-29452014000500038Species of the Annonaceae family are used all over the tropics in traditional medicine in tropical regions for the treatment of malaria and other illnesses. Phytochemical studies of this family have revealed chemical components which could offer new alternatives for the treatment and control of malaria. Searches in scientific reference sites (SciFinder Scholar, Scielo, PubMed, ScienceDirect and ISI Web of Science) and a bibliographic literature search for species of Annonaceae used traditionally to treat malaria and fever were carried out. This family contains 2,100 species in 123 genera. We encountered 113 articles reporting medicinal use of one or more species of this family including 63 species in 27 genera with uses as antimalarials and febrifuges. Even though the same species of Annonaceae are used by diverse ethnic groups, different plant parts are often chosen for applications, and diverse methods of preparation and treatment are used. The ethanol extracts of Polyalthia debilis and Xylopia aromatica proved to be quite active against Plasmodium falciparum in vitro (median inhibition concentration, ICinf50/inf < 1.5 μg/mL). Intraperitoneal injection of Annickia chlorantha aqueous extracts (cited as Enantia chlorantha) cleared chloroquine-resistant Plasmodium yoelii nigeriensis from the blood of mice in a dose-dependant manner. More phytochemical profiles of Annonaceous species are required; especially information on the more commonly distributed antimalarial compounds in this family.Volume 36, Número SPEC. EDITION 1, Pags. 315-337Attribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessAnnickia ChloranthaAnnonaceaeMusPlasmodium FalciparumPlasmodium Yoelii NigeriensisPolyalthia DebilisXylopiaPlants of the annonaceae traditionally used as antimalarials: A reviewPlantas da familia annonaceae tradicionalmente usadas como antimaláricos: Uma revisãoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRevista Brasileira de Fruticulturaporreponame:Repositório Institucional do INPAinstname:Instituto Nacional de Pesquisas da Amazônia (INPA)instacron:INPAORIGINALartigo-inpa.pdfartigo-inpa.pdfapplication/pdf482731https://repositorio.inpa.gov.br/bitstream/1/16017/1/artigo-inpa.pdf155b21ea4a653e03ae89eb8f7edc8c72MD511/160172020-07-14 11:28:18.334oai:repositorio:1/16017Repositório de PublicaçõesPUBhttps://repositorio.inpa.gov.br/oai/requestopendoar:2020-07-14T15:28:18Repositório Institucional do INPA - Instituto Nacional de Pesquisas da Amazônia (INPA)false |
dc.title.en.fl_str_mv |
Plants of the annonaceae traditionally used as antimalarials: A review |
dc.title.alternative.pt_BR.fl_str_mv |
Plantas da familia annonaceae tradicionalmente usadas como antimaláricos: Uma revisão |
title |
Plants of the annonaceae traditionally used as antimalarials: A review |
spellingShingle |
Plants of the annonaceae traditionally used as antimalarials: A review Frausin, Gina Annickia Chlorantha Annonaceae Mus Plasmodium Falciparum Plasmodium Yoelii Nigeriensis Polyalthia Debilis Xylopia |
title_short |
Plants of the annonaceae traditionally used as antimalarials: A review |
title_full |
Plants of the annonaceae traditionally used as antimalarials: A review |
title_fullStr |
Plants of the annonaceae traditionally used as antimalarials: A review |
title_full_unstemmed |
Plants of the annonaceae traditionally used as antimalarials: A review |
title_sort |
Plants of the annonaceae traditionally used as antimalarials: A review |
author |
Frausin, Gina |
author_facet |
Frausin, Gina Lima, Renata Braga Souza Hidalgo, Ari de Freitas Maas, Paul J.M. Pohlit, Adrian Martin |
author_role |
author |
author2 |
Lima, Renata Braga Souza Hidalgo, Ari de Freitas Maas, Paul J.M. Pohlit, Adrian Martin |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Frausin, Gina Lima, Renata Braga Souza Hidalgo, Ari de Freitas Maas, Paul J.M. Pohlit, Adrian Martin |
dc.subject.eng.fl_str_mv |
Annickia Chlorantha Annonaceae Mus Plasmodium Falciparum Plasmodium Yoelii Nigeriensis Polyalthia Debilis Xylopia |
topic |
Annickia Chlorantha Annonaceae Mus Plasmodium Falciparum Plasmodium Yoelii Nigeriensis Polyalthia Debilis Xylopia |
description |
Species of the Annonaceae family are used all over the tropics in traditional medicine in tropical regions for the treatment of malaria and other illnesses. Phytochemical studies of this family have revealed chemical components which could offer new alternatives for the treatment and control of malaria. Searches in scientific reference sites (SciFinder Scholar, Scielo, PubMed, ScienceDirect and ISI Web of Science) and a bibliographic literature search for species of Annonaceae used traditionally to treat malaria and fever were carried out. This family contains 2,100 species in 123 genera. We encountered 113 articles reporting medicinal use of one or more species of this family including 63 species in 27 genera with uses as antimalarials and febrifuges. Even though the same species of Annonaceae are used by diverse ethnic groups, different plant parts are often chosen for applications, and diverse methods of preparation and treatment are used. The ethanol extracts of Polyalthia debilis and Xylopia aromatica proved to be quite active against Plasmodium falciparum in vitro (median inhibition concentration, ICinf50/inf < 1.5 μg/mL). Intraperitoneal injection of Annickia chlorantha aqueous extracts (cited as Enantia chlorantha) cleared chloroquine-resistant Plasmodium yoelii nigeriensis from the blood of mice in a dose-dependant manner. More phytochemical profiles of Annonaceous species are required; especially information on the more commonly distributed antimalarial compounds in this family. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014 |
dc.date.accessioned.fl_str_mv |
2020-05-21T21:56:30Z |
dc.date.available.fl_str_mv |
2020-05-21T21:56:30Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://repositorio.inpa.gov.br/handle/1/16017 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S0100-29452014000500038 |
url |
https://repositorio.inpa.gov.br/handle/1/16017 |
identifier_str_mv |
10.1590/S0100-29452014000500038 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.ispartof.pt_BR.fl_str_mv |
Volume 36, Número SPEC. EDITION 1, Pags. 315-337 |
dc.rights.driver.fl_str_mv |
Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Revista Brasileira de Fruticultura |
publisher.none.fl_str_mv |
Revista Brasileira de Fruticultura |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional do INPA instname:Instituto Nacional de Pesquisas da Amazônia (INPA) instacron:INPA |
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Instituto Nacional de Pesquisas da Amazônia (INPA) |
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INPA |
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INPA |
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Repositório Institucional do INPA |
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Repositório Institucional do INPA |
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https://repositorio.inpa.gov.br/bitstream/1/16017/1/artigo-inpa.pdf |
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Repositório Institucional do INPA - Instituto Nacional de Pesquisas da Amazônia (INPA) |
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