Potential antimalarials from Nigerian plants: a review

Bibliographic Details
Main Author: Krettli, Antoniana Ursine
Publication Date: 2011
Other Authors: Adebayo, Joseph Oluwatope
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
Download full: https://www.arca.fiocruz.br/handle/icict/8064
Summary: Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Malaria. Belo Horizonte, MG, Brasil.
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spelling Krettli, Antoniana UrsineAdebayo, Joseph Oluwatope2014-07-23T12:59:13Z2014-07-23T12:59:13Z2011ADEBAYO, Joseph O.; KRETTLI, Antoniana Ursine. Potential antimalarials from Nigerian plants: a review. Journal of Ethnopharmacology. Journal of Ethnopharmacology, 133(2): 289-302, 2011.0378-8741https://www.arca.fiocruz.br/handle/icict/806410.1016/j.jep.2010.11.024engElsevier SequoiaPotential antimalarials from Nigerian plants: a reviewinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Malaria. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Malaria. Belo Horizonte, MG, Brasil/University of Ilorin. Department of Biochemistry. Ilorin, NigeriaMalaria, caused by parasites of the genus Plasmodium, is one of the leading infectious diseases in many tropical regions, including Nigeria, a West African country where transmission occurs all year round. Many of the inhabitants use plants as remedies against fever and other symptoms of acute malaria, as reported herein. Some of these plants have their antimalarial efficacies scientifically demonstrated and the active compounds isolated with their probable mechanisms of action studied. Medicinal plants are used to treat diseases also where the biodiversity of plants occur in parallel with endemic transmission of malaria. This review focuses on medicinal plants which are used to treat malaria in Nigeria, and on antimalarial testing of extracts and purified compounds from plants. Some show intense activity against malaria parasites in vitro and in experimentally infected mice. The search for new drugs based on plants is important due to the emergence and widespread of chloroquine-resistant and multiple drug-resistant malaria parasites, which require the development of new antimalarials. An acquaintance with antimalarial plants may be a springboard for new phytotherapies that could be affordable to treat malaria, especially among the less privileged native people living in endemic areas of the tropics, mostly at risk of this devastating disease.AntimalarialEthnomedicineMedicinal plantsNigeriaPlasmodium falciparuminfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALPotential antimalarials from Nigerian plants.pdfPotential antimalarials from Nigerian plants.pdfapplication/pdf3821588https://www.arca.fiocruz.br/bitstream/icict/8064/1/Potential%20antimalarials%20from%20Nigerian%20plants.pdf719fb71a66901774ea16aaaede3ce859MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/8064/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTPotential antimalarials from Nigerian plants.pdf.txtPotential antimalarials from Nigerian plants.pdf.txtExtracted texttext/plain14https://www.arca.fiocruz.br/bitstream/icict/8064/3/Potential%20antimalarials%20from%20Nigerian%20plants.pdf.txt06b7e51e8fc077b8c75076712e4dd2b3MD53icict/80642022-11-29 15:47:42.221oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-11-29T18:47:42Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Potential antimalarials from Nigerian plants: a review
title Potential antimalarials from Nigerian plants: a review
spellingShingle Potential antimalarials from Nigerian plants: a review
Krettli, Antoniana Ursine
Antimalarial
Ethnomedicine
Medicinal plants
Nigeria
Plasmodium falciparum
title_short Potential antimalarials from Nigerian plants: a review
title_full Potential antimalarials from Nigerian plants: a review
title_fullStr Potential antimalarials from Nigerian plants: a review
title_full_unstemmed Potential antimalarials from Nigerian plants: a review
title_sort Potential antimalarials from Nigerian plants: a review
author Krettli, Antoniana Ursine
author_facet Krettli, Antoniana Ursine
Adebayo, Joseph Oluwatope
author_role author
author2 Adebayo, Joseph Oluwatope
author2_role author
dc.contributor.author.fl_str_mv Krettli, Antoniana Ursine
Adebayo, Joseph Oluwatope
dc.subject.en.pt_BR.fl_str_mv Antimalarial
Ethnomedicine
Medicinal plants
Nigeria
Plasmodium falciparum
topic Antimalarial
Ethnomedicine
Medicinal plants
Nigeria
Plasmodium falciparum
description Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Malaria. Belo Horizonte, MG, Brasil.
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2014-07-23T12:59:13Z
dc.date.available.fl_str_mv 2014-07-23T12:59:13Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ADEBAYO, Joseph O.; KRETTLI, Antoniana Ursine. Potential antimalarials from Nigerian plants: a review. Journal of Ethnopharmacology. Journal of Ethnopharmacology, 133(2): 289-302, 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/8064
dc.identifier.issn.none.fl_str_mv 0378-8741
dc.identifier.doi.none.fl_str_mv 10.1016/j.jep.2010.11.024
identifier_str_mv ADEBAYO, Joseph O.; KRETTLI, Antoniana Ursine. Potential antimalarials from Nigerian plants: a review. Journal of Ethnopharmacology. Journal of Ethnopharmacology, 133(2): 289-302, 2011.
0378-8741
10.1016/j.jep.2010.11.024
url https://www.arca.fiocruz.br/handle/icict/8064
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier Sequoia
publisher.none.fl_str_mv Elsevier Sequoia
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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