NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)

Detalhes bibliográficos
Autor(a) principal: Carlos Alberto Yasin Wayhs
Data de Publicação: 2018
Outros Autores: Monique dos Reis, Kristiane de Cássia Mariotti, Wanderson Romão, Boniek Gontijo Vaz, Fabiano Barreto, Rafael Scorsatto Ortiz, Renata Pereira Limberger
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Forensic Sciences, Medical Law and Bioethics
Texto Completo: https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686
Resumo: The NBOMes are classified as new psychoactive substances and have recently become popular as drugs of abuse, being associated with several intoxication cases and even deaths, leading to its ban in several countries. Until now, the most widely used analytical instrument among forensic laboratories in Brazil is GC-MS. In this study, this instrumentation was employed for routine analyzes of twenty blotter paper seizure by Brazilian Federal Police (BFP) in the southernmost state of the country. However, to acquire more information about these samples, LC-QTOF/MS was used as a supplementary analysis to determinate degradation products, metabolites and unknown compounds. The GC-MS analysis detected only 25B-NBOMe, while the LC-QTOF/MS analysis detected 25B-NBOMe, 2C-B and MDMA. The compounds found in these analyzes are quite different from that found in the national profile of seizures by BFP, suggesting that another rout or supplier act in this region. For research and drug intelligence purposes the use of more versatile, sensitive and specific analytical tool provides a greater number of information that could be employed as a valuable strategy in the drug trafficking combat.
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spelling NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)Designer drugsNBOMe25B-NBOMeGC-MSLC-QTOF/MSThe NBOMes are classified as new psychoactive substances and have recently become popular as drugs of abuse, being associated with several intoxication cases and even deaths, leading to its ban in several countries. Until now, the most widely used analytical instrument among forensic laboratories in Brazil is GC-MS. In this study, this instrumentation was employed for routine analyzes of twenty blotter paper seizure by Brazilian Federal Police (BFP) in the southernmost state of the country. However, to acquire more information about these samples, LC-QTOF/MS was used as a supplementary analysis to determinate degradation products, metabolites and unknown compounds. The GC-MS analysis detected only 25B-NBOMe, while the LC-QTOF/MS analysis detected 25B-NBOMe, 2C-B and MDMA. The compounds found in these analyzes are quite different from that found in the national profile of seizures by BFP, suggesting that another rout or supplier act in this region. For research and drug intelligence purposes the use of more versatile, sensitive and specific analytical tool provides a greater number of information that could be employed as a valuable strategy in the drug trafficking combat.IPEBJ2018-05-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigo Originalinfo:eu-repo/semantics/articleapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documenthttps://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/68610.17063/bjfs7(3)y2018193Brazilian Journal of Forensic Sciences, Medical Law and Bioethics; v. 7 n. 3 (2018): Volume 7 - Número 3; 193-204Brazilian Journal of Forensic Sciences, Medical Law and Bioethics; Vol. 7 No. 3 (2018): Volume 7 - Número 3; 193-2042237-261Xreponame:Brazilian Journal of Forensic Sciences, Medical Law and Bioethicsinstname:Instituto Paulista de Estudos Bioéticos e Jurídicos (IPEBJ)instacron:IPEBJenghttps://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686/804https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686/805Carlos Alberto Yasin WayhsMonique dos ReisKristiane de Cássia MariottiWanderson RomãoBoniek Gontijo VazFabiano BarretoRafael Scorsatto OrtizRenata Pereira Limbergerinfo:eu-repo/semantics/openAccess2021-04-22T12:23:03Zoai:bjfs:article/686Revistahttps://www.ipebj.com.br/bjfs/index.php/bjfs/homePRIhttps://www.ipebj.com.br/bjfs/index.php/bjfs/oai2237-261X2237-261Xopendoar:2021-04-22 12:23:05.395Brazilian Journal of Forensic Sciences, Medical Law and Bioethics - Instituto Paulista de Estudos Bioéticos e Jurídicos (IPEBJ)false
dc.title.none.fl_str_mv NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)
title NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)
spellingShingle NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)
Carlos Alberto Yasin Wayhs
Designer drugs
NBOMe
25B-NBOMe
GC-MS
LC-QTOF/MS
title_short NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)
title_full NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)
title_fullStr NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)
title_full_unstemmed NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)
title_sort NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)
author Carlos Alberto Yasin Wayhs
author_facet Carlos Alberto Yasin Wayhs
Monique dos Reis
Kristiane de Cássia Mariotti
Wanderson Romão
Boniek Gontijo Vaz
Fabiano Barreto
Rafael Scorsatto Ortiz
Renata Pereira Limberger
author_role author
author2 Monique dos Reis
Kristiane de Cássia Mariotti
Wanderson Romão
Boniek Gontijo Vaz
Fabiano Barreto
Rafael Scorsatto Ortiz
Renata Pereira Limberger
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Carlos Alberto Yasin Wayhs
Monique dos Reis
Kristiane de Cássia Mariotti
Wanderson Romão
Boniek Gontijo Vaz
Fabiano Barreto
Rafael Scorsatto Ortiz
Renata Pereira Limberger
dc.subject.por.fl_str_mv Designer drugs
NBOMe
25B-NBOMe
GC-MS
LC-QTOF/MS
topic Designer drugs
NBOMe
25B-NBOMe
GC-MS
LC-QTOF/MS
dc.description.none.fl_txt_mv The NBOMes are classified as new psychoactive substances and have recently become popular as drugs of abuse, being associated with several intoxication cases and even deaths, leading to its ban in several countries. Until now, the most widely used analytical instrument among forensic laboratories in Brazil is GC-MS. In this study, this instrumentation was employed for routine analyzes of twenty blotter paper seizure by Brazilian Federal Police (BFP) in the southernmost state of the country. However, to acquire more information about these samples, LC-QTOF/MS was used as a supplementary analysis to determinate degradation products, metabolites and unknown compounds. The GC-MS analysis detected only 25B-NBOMe, while the LC-QTOF/MS analysis detected 25B-NBOMe, 2C-B and MDMA. The compounds found in these analyzes are quite different from that found in the national profile of seizures by BFP, suggesting that another rout or supplier act in this region. For research and drug intelligence purposes the use of more versatile, sensitive and specific analytical tool provides a greater number of information that could be employed as a valuable strategy in the drug trafficking combat.
description The NBOMes are classified as new psychoactive substances and have recently become popular as drugs of abuse, being associated with several intoxication cases and even deaths, leading to its ban in several countries. Until now, the most widely used analytical instrument among forensic laboratories in Brazil is GC-MS. In this study, this instrumentation was employed for routine analyzes of twenty blotter paper seizure by Brazilian Federal Police (BFP) in the southernmost state of the country. However, to acquire more information about these samples, LC-QTOF/MS was used as a supplementary analysis to determinate degradation products, metabolites and unknown compounds. The GC-MS analysis detected only 25B-NBOMe, while the LC-QTOF/MS analysis detected 25B-NBOMe, 2C-B and MDMA. The compounds found in these analyzes are quite different from that found in the national profile of seizures by BFP, suggesting that another rout or supplier act in this region. For research and drug intelligence purposes the use of more versatile, sensitive and specific analytical tool provides a greater number of information that could be employed as a valuable strategy in the drug trafficking combat.
publishDate 2018
dc.date.none.fl_str_mv 2018-05-16
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigo Original
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686
10.17063/bjfs7(3)y2018193
url https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686
identifier_str_mv 10.17063/bjfs7(3)y2018193
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686/804
https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686/805
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/vnd.openxmlformats-officedocument.wordprocessingml.document
dc.publisher.none.fl_str_mv IPEBJ
publisher.none.fl_str_mv IPEBJ
dc.source.none.fl_str_mv Brazilian Journal of Forensic Sciences, Medical Law and Bioethics; v. 7 n. 3 (2018): Volume 7 - Número 3; 193-204
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics; Vol. 7 No. 3 (2018): Volume 7 - Número 3; 193-204
2237-261X
reponame:Brazilian Journal of Forensic Sciences, Medical Law and Bioethics
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instname_str Instituto Paulista de Estudos Bioéticos e Jurídicos (IPEBJ)
instacron_str IPEBJ
institution IPEBJ
repository.name.fl_str_mv Brazilian Journal of Forensic Sciences, Medical Law and Bioethics - Instituto Paulista de Estudos Bioéticos e Jurídicos (IPEBJ)
repository.mail.fl_str_mv
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