NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Forensic Sciences, Medical Law and Bioethics |
Texto Completo: | https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686 |
Resumo: | The NBOMes are classified as new psychoactive substances and have recently become popular as drugs of abuse, being associated with several intoxication cases and even deaths, leading to its ban in several countries. Until now, the most widely used analytical instrument among forensic laboratories in Brazil is GC-MS. In this study, this instrumentation was employed for routine analyzes of twenty blotter paper seizure by Brazilian Federal Police (BFP) in the southernmost state of the country. However, to acquire more information about these samples, LC-QTOF/MS was used as a supplementary analysis to determinate degradation products, metabolites and unknown compounds. The GC-MS analysis detected only 25B-NBOMe, while the LC-QTOF/MS analysis detected 25B-NBOMe, 2C-B and MDMA. The compounds found in these analyzes are quite different from that found in the national profile of seizures by BFP, suggesting that another rout or supplier act in this region. For research and drug intelligence purposes the use of more versatile, sensitive and specific analytical tool provides a greater number of information that could be employed as a valuable strategy in the drug trafficking combat. |
id |
IPEBJ_e9511c75b161a5c7ea7c51c589a4568f |
---|---|
oai_identifier_str |
oai:bjfs:article/686 |
network_acronym_str |
IPEBJ |
network_name_str |
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics |
spelling |
NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil)Designer drugsNBOMe25B-NBOMeGC-MSLC-QTOF/MSThe NBOMes are classified as new psychoactive substances and have recently become popular as drugs of abuse, being associated with several intoxication cases and even deaths, leading to its ban in several countries. Until now, the most widely used analytical instrument among forensic laboratories in Brazil is GC-MS. In this study, this instrumentation was employed for routine analyzes of twenty blotter paper seizure by Brazilian Federal Police (BFP) in the southernmost state of the country. However, to acquire more information about these samples, LC-QTOF/MS was used as a supplementary analysis to determinate degradation products, metabolites and unknown compounds. The GC-MS analysis detected only 25B-NBOMe, while the LC-QTOF/MS analysis detected 25B-NBOMe, 2C-B and MDMA. The compounds found in these analyzes are quite different from that found in the national profile of seizures by BFP, suggesting that another rout or supplier act in this region. For research and drug intelligence purposes the use of more versatile, sensitive and specific analytical tool provides a greater number of information that could be employed as a valuable strategy in the drug trafficking combat.IPEBJ2018-05-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigo Originalinfo:eu-repo/semantics/articleapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documenthttps://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/68610.17063/bjfs7(3)y2018193Brazilian Journal of Forensic Sciences, Medical Law and Bioethics; v. 7 n. 3 (2018): Volume 7 - Número 3; 193-204Brazilian Journal of Forensic Sciences, Medical Law and Bioethics; Vol. 7 No. 3 (2018): Volume 7 - Número 3; 193-2042237-261Xreponame:Brazilian Journal of Forensic Sciences, Medical Law and Bioethicsinstname:Instituto Paulista de Estudos Bioéticos e Jurídicos (IPEBJ)instacron:IPEBJenghttps://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686/804https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686/805Carlos Alberto Yasin WayhsMonique dos ReisKristiane de Cássia MariottiWanderson RomãoBoniek Gontijo VazFabiano BarretoRafael Scorsatto OrtizRenata Pereira Limbergerinfo:eu-repo/semantics/openAccess2021-04-22T12:23:03Zoai:bjfs:article/686Revistahttps://www.ipebj.com.br/bjfs/index.php/bjfs/homePRIhttps://www.ipebj.com.br/bjfs/index.php/bjfs/oai2237-261X2237-261Xopendoar:2021-04-22 12:23:05.395Brazilian Journal of Forensic Sciences, Medical Law and Bioethics - Instituto Paulista de Estudos Bioéticos e Jurídicos (IPEBJ)false |
dc.title.none.fl_str_mv |
NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil) |
title |
NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil) |
spellingShingle |
NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil) Carlos Alberto Yasin Wayhs Designer drugs NBOMe 25B-NBOMe GC-MS LC-QTOF/MS |
title_short |
NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil) |
title_full |
NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil) |
title_fullStr |
NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil) |
title_full_unstemmed |
NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil) |
title_sort |
NBOMe Designer Drugs: GC-MS and LC-QTOF/MS Detection on Blotter Paper by Brazilian Federal Police (Rio Grande do Sul, Brazil) |
author |
Carlos Alberto Yasin Wayhs |
author_facet |
Carlos Alberto Yasin Wayhs Monique dos Reis Kristiane de Cássia Mariotti Wanderson Romão Boniek Gontijo Vaz Fabiano Barreto Rafael Scorsatto Ortiz Renata Pereira Limberger |
author_role |
author |
author2 |
Monique dos Reis Kristiane de Cássia Mariotti Wanderson Romão Boniek Gontijo Vaz Fabiano Barreto Rafael Scorsatto Ortiz Renata Pereira Limberger |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Carlos Alberto Yasin Wayhs Monique dos Reis Kristiane de Cássia Mariotti Wanderson Romão Boniek Gontijo Vaz Fabiano Barreto Rafael Scorsatto Ortiz Renata Pereira Limberger |
dc.subject.por.fl_str_mv |
Designer drugs NBOMe 25B-NBOMe GC-MS LC-QTOF/MS |
topic |
Designer drugs NBOMe 25B-NBOMe GC-MS LC-QTOF/MS |
dc.description.none.fl_txt_mv |
The NBOMes are classified as new psychoactive substances and have recently become popular as drugs of abuse, being associated with several intoxication cases and even deaths, leading to its ban in several countries. Until now, the most widely used analytical instrument among forensic laboratories in Brazil is GC-MS. In this study, this instrumentation was employed for routine analyzes of twenty blotter paper seizure by Brazilian Federal Police (BFP) in the southernmost state of the country. However, to acquire more information about these samples, LC-QTOF/MS was used as a supplementary analysis to determinate degradation products, metabolites and unknown compounds. The GC-MS analysis detected only 25B-NBOMe, while the LC-QTOF/MS analysis detected 25B-NBOMe, 2C-B and MDMA. The compounds found in these analyzes are quite different from that found in the national profile of seizures by BFP, suggesting that another rout or supplier act in this region. For research and drug intelligence purposes the use of more versatile, sensitive and specific analytical tool provides a greater number of information that could be employed as a valuable strategy in the drug trafficking combat. |
description |
The NBOMes are classified as new psychoactive substances and have recently become popular as drugs of abuse, being associated with several intoxication cases and even deaths, leading to its ban in several countries. Until now, the most widely used analytical instrument among forensic laboratories in Brazil is GC-MS. In this study, this instrumentation was employed for routine analyzes of twenty blotter paper seizure by Brazilian Federal Police (BFP) in the southernmost state of the country. However, to acquire more information about these samples, LC-QTOF/MS was used as a supplementary analysis to determinate degradation products, metabolites and unknown compounds. The GC-MS analysis detected only 25B-NBOMe, while the LC-QTOF/MS analysis detected 25B-NBOMe, 2C-B and MDMA. The compounds found in these analyzes are quite different from that found in the national profile of seizures by BFP, suggesting that another rout or supplier act in this region. For research and drug intelligence purposes the use of more versatile, sensitive and specific analytical tool provides a greater number of information that could be employed as a valuable strategy in the drug trafficking combat. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-05-16 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo Original info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686 10.17063/bjfs7(3)y2018193 |
url |
https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686 |
identifier_str_mv |
10.17063/bjfs7(3)y2018193 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686/804 https://www.ipebj.com.br/bjfs/index.php/bjfs/article/view/686/805 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/vnd.openxmlformats-officedocument.wordprocessingml.document |
dc.publisher.none.fl_str_mv |
IPEBJ |
publisher.none.fl_str_mv |
IPEBJ |
dc.source.none.fl_str_mv |
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics; v. 7 n. 3 (2018): Volume 7 - Número 3; 193-204 Brazilian Journal of Forensic Sciences, Medical Law and Bioethics; Vol. 7 No. 3 (2018): Volume 7 - Número 3; 193-204 2237-261X reponame:Brazilian Journal of Forensic Sciences, Medical Law and Bioethics instname:Instituto Paulista de Estudos Bioéticos e Jurídicos (IPEBJ) instacron:IPEBJ |
reponame_str |
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics |
collection |
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics |
instname_str |
Instituto Paulista de Estudos Bioéticos e Jurídicos (IPEBJ) |
instacron_str |
IPEBJ |
institution |
IPEBJ |
repository.name.fl_str_mv |
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics - Instituto Paulista de Estudos Bioéticos e Jurídicos (IPEBJ) |
repository.mail.fl_str_mv |
|
_version_ |
1697756591916318720 |