Dose evaluation in breast brachytherapy using different 125I seeds
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo de conferência |
Título da fonte: | Repositório Institucional do IPEN |
Texto Completo: | http://repositorio.ipen.br/handle/123456789/30989 |
Resumo: | A very common type of cancer among women is the breast cancer. The treatment choice depends, among several factors, on the clinical stage of the disease and the age. One way to treat breast cancer is the permanent breast seed implant, with Iodine-125 (125I). Since they present some advantages: possibility to treat solid tumors, near the tumor site, induction of little trauma and strong lethality to cancer cells. In Brazil, a new 125I seed was developed at the Instituto de Pesquisas Energ??ticas e Nucleares to be applied in brachytherapy. Given the large number of women diagnosed with breast cancer, in this work, the dose determination in organs and tissues was undertaken, considering this new seed and a commercial, Amersham 6711-Oncoseed??, employing the Monte Carlo method. Moreover, for a better understanding of the radiation doses delivered to different patients, the breast volumes were modified. For this purpose, the MCNPX Monte Carlo code was utilized coupled with female virtual anthropomorphic phantoms. The results pointed out the highest dose values for the breast and skin. Furthermore, the dose results for both types of seeds were very similar. |
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2020-03-30T14:27:23Z2020-03-30T14:27:23Z24-27 de novembro, 2019http://repositorio.ipen.br/handle/123456789/309890000-0002-7362-2455A very common type of cancer among women is the breast cancer. The treatment choice depends, among several factors, on the clinical stage of the disease and the age. One way to treat breast cancer is the permanent breast seed implant, with Iodine-125 (125I). Since they present some advantages: possibility to treat solid tumors, near the tumor site, induction of little trauma and strong lethality to cancer cells. In Brazil, a new 125I seed was developed at the Instituto de Pesquisas Energ??ticas e Nucleares to be applied in brachytherapy. Given the large number of women diagnosed with breast cancer, in this work, the dose determination in organs and tissues was undertaken, considering this new seed and a commercial, Amersham 6711-Oncoseed??, employing the Monte Carlo method. Moreover, for a better understanding of the radiation doses delivered to different patients, the breast volumes were modified. For this purpose, the MCNPX Monte Carlo code was utilized coupled with female virtual anthropomorphic phantoms. The results pointed out the highest dose values for the breast and skin. Furthermore, the dose results for both types of seeds were very similar.Submitted by Pedro Silva Filho (pfsilva@ipen.br) on 2020-03-30T14:27:23Z No. of bitstreams: 1 26786.pdf: 800030 bytes, checksum: 32cfa1cbad012a29b5161ceb867b1db5 (MD5)Made available in DSpace on 2020-03-30T14:27:23Z (GMT). No. of bitstreams: 1 26786.pdf: 800030 bytes, checksum: 32cfa1cbad012a29b5161ceb867b1db5 (MD5)Funda????o de Amparo ?? Pesquisa do Estado de Minas Gerais (FAPEMIG)Conselho Nacional de Desenvolvimento Cient??fico e Tecnol??gico (CNPq)FAPEMIG: APQ-03049-15; APQ-02934-15CNPq: 421603/2016-0; 420699/2016-3; 301335/2016-8Sociedade Brasileira de MetrologiaDose evaluation in breast brachytherapy using different 125I seedsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectNRio de Janeiro, RJFlorian??polis, SC121131495600600SANTOS, WILLIAM S.SANTOS, CARLA J.SILVA, ALINE F. daSOUZA, SAMARA P.NEVES, LUCIO P.BELINATO, WALMIRCALDAS, LINDA V.E.PERINI, ANA P.CONGRESSO BRASILEIRO DE METROLOGIA, 10.; CONGRESSO INTERNACIONAL DE METROLOGIA EL??TRICA, 13.; CONGRESSO INTERNACIONAL DE METROLOGIA MEC??NICA, 5.; CONGRESSO BRASILEIRO DE METROLOGIA DAS RADIA????ES IONIZANTES, 6.; WORKSHOP DA REDE DE METROLOGIA QU??MICA DO INMETRO, 4.; CONGRESSO BRASILEIRO DE METROLOGIA ??PTICA, 3.info:eu-repo/semantics/openAccessreponame:Repositório Institucional do IPENinstname:Instituto de Pesquisas Energéticas e Nucleares (IPEN)instacron:IPEN267862019CALDAS, LINDA V.E.SANTOS, WILLIAM S.20-03Anais149512113a Monte Carlo approachCALDAS, LINDA V.E.:1495:330:NSANTOS, WILLIAM S.:12113:330:SORIGINAL26786.pdf26786.pdfapplication/pdf800030http://repositorio.ipen.br/bitstream/123456789/30989/1/26786.pdf32cfa1cbad012a29b5161ceb867b1db5MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.ipen.br/bitstream/123456789/30989/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52123456789/309892020-03-30 14:27:23.472oai:repositorio.ipen.br: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Repositório InstitucionalPUBhttp://repositorio.ipen.br/oai/requestbibl@ipen.bropendoar:45102020-03-30T14:27:23Repositório Institucional do IPEN - Instituto de Pesquisas Energéticas e Nucleares (IPEN)false |
dc.title.pt_BR.fl_str_mv |
Dose evaluation in breast brachytherapy using different 125I seeds |
title |
Dose evaluation in breast brachytherapy using different 125I seeds |
spellingShingle |
Dose evaluation in breast brachytherapy using different 125I seeds SANTOS, WILLIAM S. |
title_short |
Dose evaluation in breast brachytherapy using different 125I seeds |
title_full |
Dose evaluation in breast brachytherapy using different 125I seeds |
title_fullStr |
Dose evaluation in breast brachytherapy using different 125I seeds |
title_full_unstemmed |
Dose evaluation in breast brachytherapy using different 125I seeds |
title_sort |
Dose evaluation in breast brachytherapy using different 125I seeds |
author |
SANTOS, WILLIAM S. |
author_facet |
SANTOS, WILLIAM S. SANTOS, CARLA J. SILVA, ALINE F. da SOUZA, SAMARA P. NEVES, LUCIO P. BELINATO, WALMIR CALDAS, LINDA V.E. PERINI, ANA P. CONGRESSO BRASILEIRO DE METROLOGIA, 10.; CONGRESSO INTERNACIONAL DE METROLOGIA EL??TRICA, 13.; CONGRESSO INTERNACIONAL DE METROLOGIA MEC??NICA, 5.; CONGRESSO BRASILEIRO DE METROLOGIA DAS RADIA????ES IONIZANTES, 6.; WORKSHOP DA REDE DE METROLOGIA QU??MICA DO INMETRO, 4.; CONGRESSO BRASILEIRO DE METROLOGIA ??PTICA, 3. |
author_role |
author |
author2 |
SANTOS, CARLA J. SILVA, ALINE F. da SOUZA, SAMARA P. NEVES, LUCIO P. BELINATO, WALMIR CALDAS, LINDA V.E. PERINI, ANA P. CONGRESSO BRASILEIRO DE METROLOGIA, 10.; CONGRESSO INTERNACIONAL DE METROLOGIA EL??TRICA, 13.; CONGRESSO INTERNACIONAL DE METROLOGIA MEC??NICA, 5.; CONGRESSO BRASILEIRO DE METROLOGIA DAS RADIA????ES IONIZANTES, 6.; WORKSHOP DA REDE DE METROLOGIA QU??MICA DO INMETRO, 4.; CONGRESSO BRASILEIRO DE METROLOGIA ??PTICA, 3. |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
SANTOS, WILLIAM S. SANTOS, CARLA J. SILVA, ALINE F. da SOUZA, SAMARA P. NEVES, LUCIO P. BELINATO, WALMIR CALDAS, LINDA V.E. PERINI, ANA P. CONGRESSO BRASILEIRO DE METROLOGIA, 10.; CONGRESSO INTERNACIONAL DE METROLOGIA EL??TRICA, 13.; CONGRESSO INTERNACIONAL DE METROLOGIA MEC??NICA, 5.; CONGRESSO BRASILEIRO DE METROLOGIA DAS RADIA????ES IONIZANTES, 6.; WORKSHOP DA REDE DE METROLOGIA QU??MICA DO INMETRO, 4.; CONGRESSO BRASILEIRO DE METROLOGIA ??PTICA, 3. |
description |
A very common type of cancer among women is the breast cancer. The treatment choice depends, among several factors, on the clinical stage of the disease and the age. One way to treat breast cancer is the permanent breast seed implant, with Iodine-125 (125I). Since they present some advantages: possibility to treat solid tumors, near the tumor site, induction of little trauma and strong lethality to cancer cells. In Brazil, a new 125I seed was developed at the Instituto de Pesquisas Energ??ticas e Nucleares to be applied in brachytherapy. Given the large number of women diagnosed with breast cancer, in this work, the dose determination in organs and tissues was undertaken, considering this new seed and a commercial, Amersham 6711-Oncoseed??, employing the Monte Carlo method. Moreover, for a better understanding of the radiation doses delivered to different patients, the breast volumes were modified. For this purpose, the MCNPX Monte Carlo code was utilized coupled with female virtual anthropomorphic phantoms. The results pointed out the highest dose values for the breast and skin. Furthermore, the dose results for both types of seeds were very similar. |
publishDate |
2020 |
dc.date.evento.pt_BR.fl_str_mv |
24-27 de novembro, 2019 |
dc.date.accessioned.fl_str_mv |
2020-03-30T14:27:23Z |
dc.date.available.fl_str_mv |
2020-03-30T14:27:23Z |
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Sociedade Brasileira de Metrologia |
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Sociedade Brasileira de Metrologia |
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