Experimental design technique applied to the validation of an instrumental neutron activation analysis procedure
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo de conferência |
Título da fonte: | Repositório Institucional do IPEN |
Texto Completo: | http://repositorio.ipen.br/handle/123456789/28317 |
Resumo: | In this study optimization of procedures and standardization of Instrumental Neutron Activation Analysis (INAA) method were carried out for the determination of the elements bromine, chlorine, magnesium, manganese, potassium, sodium and vanadium in biological matrix materials using short irradiations at a pneumatic system. 2k experimental designs were applied for evaluation of the individual contribution of selected variables of the analytical procedure in the final mass fraction result. The chosen experimental designs were the 23 and the 24, depending on the radionuclide half life. Different certified reference materials and multi-element comparators were analyzed considering the following variables: sample decay time, irradiation time, counting time and sample distance to detector. Comparator concentration, sample mass and irradiation time were maintained constant in this procedure. By means of the statistical analysis and theoretical and experimental considerations, it was determined the optimized experimental conditions for the analytical methods that will be adopted for the validation procedure of INAA methods in the Neutron Activation Analysis Laboratory (LAN) of the Research Reactor Center (CRPq) at the Nuclear and Energy Research Institute (IPEN ??? CNEN/SP). Optimized conditions were estimated based on the results of z-score tests, main effect, interaction effects and better irradiation conditions. |
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2018-01-15T15:30:50Z2018-01-15T15:30:50ZOctober 22-27, 2017http://repositorio.ipen.br/handle/123456789/28317In this study optimization of procedures and standardization of Instrumental Neutron Activation Analysis (INAA) method were carried out for the determination of the elements bromine, chlorine, magnesium, manganese, potassium, sodium and vanadium in biological matrix materials using short irradiations at a pneumatic system. 2k experimental designs were applied for evaluation of the individual contribution of selected variables of the analytical procedure in the final mass fraction result. The chosen experimental designs were the 23 and the 24, depending on the radionuclide half life. Different certified reference materials and multi-element comparators were analyzed considering the following variables: sample decay time, irradiation time, counting time and sample distance to detector. Comparator concentration, sample mass and irradiation time were maintained constant in this procedure. By means of the statistical analysis and theoretical and experimental considerations, it was determined the optimized experimental conditions for the analytical methods that will be adopted for the validation procedure of INAA methods in the Neutron Activation Analysis Laboratory (LAN) of the Research Reactor Center (CRPq) at the Nuclear and Energy Research Institute (IPEN ??? CNEN/SP). Optimized conditions were estimated based on the results of z-score tests, main effect, interaction effects and better irradiation conditions.Submitted by Marco Antonio Oliveira da Silva (maosilva@ipen.br) on 2018-01-15T15:30:50Z No. of bitstreams: 1 24152.pdf: 256040 bytes, checksum: bae1e92fecfb0bc9f0e4048365f815e6 (MD5)Made available in DSpace on 2018-01-15T15:30:50Z (GMT). No. of bitstreams: 1 24152.pdf: 256040 bytes, checksum: bae1e92fecfb0bc9f0e4048365f815e6 (MD5)Associa????o Brasileira de Energia Nuclearbiological materialsconcentration ratioelementsexperimental datahigh-purity ge detectorsneutron activation analysisoptimizationstandardizationvalidationExperimental design technique applied to the validation of an instrumental neutron activation analysis procedureinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectINACIRio de Janeiro, RJBelo Horizonte, MGSANTOS, UANDA P. de M. dosMOREIRA, EDSON G.INTERNATIONAL NUCLEAR ATLANTIC CONFERENCEinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional do IPENinstname:Instituto de Pesquisas Energéticas e Nucleares (IPEN)instacron:IPEN241522017SANTOS, UANDA P. de M. dosMOREIRA, EDSON G.18-01Proceedings11659860SANTOS, UANDA P. DE M. DOS:11659:320:SMOREIRA, EDSON G.:860:320:NORIGINAL24152.pdf24152.pdfapplication/pdf256040http://repositorio.ipen.br/bitstream/123456789/28317/1/24152.pdfbae1e92fecfb0bc9f0e4048365f815e6MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.ipen.br/bitstream/123456789/28317/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52123456789/283172022-08-05 19:02:28.224oai:repositorio.ipen.br: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Repositório InstitucionalPUBhttp://repositorio.ipen.br/oai/requestbibl@ipen.bropendoar:45102022-08-05T19:02:28Repositório Institucional do IPEN - Instituto de Pesquisas Energéticas e Nucleares (IPEN)false |
dc.title.pt_BR.fl_str_mv |
Experimental design technique applied to the validation of an instrumental neutron activation analysis procedure |
title |
Experimental design technique applied to the validation of an instrumental neutron activation analysis procedure |
spellingShingle |
Experimental design technique applied to the validation of an instrumental neutron activation analysis procedure SANTOS, UANDA P. de M. dos biological materials concentration ratio elements experimental data high-purity ge detectors neutron activation analysis optimization standardization validation |
title_short |
Experimental design technique applied to the validation of an instrumental neutron activation analysis procedure |
title_full |
Experimental design technique applied to the validation of an instrumental neutron activation analysis procedure |
title_fullStr |
Experimental design technique applied to the validation of an instrumental neutron activation analysis procedure |
title_full_unstemmed |
Experimental design technique applied to the validation of an instrumental neutron activation analysis procedure |
title_sort |
Experimental design technique applied to the validation of an instrumental neutron activation analysis procedure |
author |
SANTOS, UANDA P. de M. dos |
author_facet |
SANTOS, UANDA P. de M. dos MOREIRA, EDSON G. INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE |
author_role |
author |
author2 |
MOREIRA, EDSON G. INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
SANTOS, UANDA P. de M. dos MOREIRA, EDSON G. INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE |
dc.subject.por.fl_str_mv |
biological materials concentration ratio elements experimental data high-purity ge detectors neutron activation analysis optimization standardization validation |
topic |
biological materials concentration ratio elements experimental data high-purity ge detectors neutron activation analysis optimization standardization validation |
description |
In this study optimization of procedures and standardization of Instrumental Neutron Activation Analysis (INAA) method were carried out for the determination of the elements bromine, chlorine, magnesium, manganese, potassium, sodium and vanadium in biological matrix materials using short irradiations at a pneumatic system. 2k experimental designs were applied for evaluation of the individual contribution of selected variables of the analytical procedure in the final mass fraction result. The chosen experimental designs were the 23 and the 24, depending on the radionuclide half life. Different certified reference materials and multi-element comparators were analyzed considering the following variables: sample decay time, irradiation time, counting time and sample distance to detector. Comparator concentration, sample mass and irradiation time were maintained constant in this procedure. By means of the statistical analysis and theoretical and experimental considerations, it was determined the optimized experimental conditions for the analytical methods that will be adopted for the validation procedure of INAA methods in the Neutron Activation Analysis Laboratory (LAN) of the Research Reactor Center (CRPq) at the Nuclear and Energy Research Institute (IPEN ??? CNEN/SP). Optimized conditions were estimated based on the results of z-score tests, main effect, interaction effects and better irradiation conditions. |
publishDate |
2018 |
dc.date.evento.pt_BR.fl_str_mv |
October 22-27, 2017 |
dc.date.accessioned.fl_str_mv |
2018-01-15T15:30:50Z |
dc.date.available.fl_str_mv |
2018-01-15T15:30:50Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
format |
conferenceObject |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ipen.br/handle/123456789/28317 |
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http://repositorio.ipen.br/handle/123456789/28317 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.coverage.pt_BR.fl_str_mv |
I |
dc.publisher.none.fl_str_mv |
Associa????o Brasileira de Energia Nuclear |
publisher.none.fl_str_mv |
Associa????o Brasileira de Energia Nuclear |
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reponame:Repositório Institucional do IPEN instname:Instituto de Pesquisas Energéticas e Nucleares (IPEN) instacron:IPEN |
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IPEN |
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IPEN |
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Repositório Institucional do IPEN |
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Repositório Institucional do IPEN |
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