Fibras de fosfato de c??lcio amorfo para regenera????o ??ssea: a bioatividade potencializada pela morfologia

• Autor(a) principal: SILVA, A.C.
• Data de Publicação: 2017
• Outros Autores: ALLEGRINI-JUNIOR, S., OTTONI, C., MELLO-CASTANHO, S.R.H., BRAGA, F.J.C., CONGRESSO BRASILEIRO DE CERAMICA, 60.
• Tipo de documento: Artigo de conferência
• Título da fonte: Repositório Institucional do IPEN
• Texto Completo: http://repositorio.ipen.br/handle/123456789/27441

Amorphous Calcium Phosphate (ACP) is the first mineral phase formed in hard tissues. ACP has low ordering in the crystal lattice compared to other calcium phosphates. The X-ray diffraction pattern is broad and diffuse with a maximum at 250 (2??), being considered as a precursor of well crystallized hydroxyapatite (HA), reference bone grafting material in odontology and medicine. The ACP graft has high capacity to be resorbable and has been widely studied as a filler for bone defects. However, it is rare to find articles where the ACP is presented in the form of fibers and yet always containing silicon. This research paper presents the ACP fibers obtained by the process Hager-Rosengarth, confirming its amorphous condition by means of X-ray diffraction and its capacity of resorption and ability to conduct and formation of new bone tissue proven by test "in vivo" with subsequent analysis by light microscopy. ACP in the form of fibers is considered innovation as a bone grafting material, having already its exclusive rights of patent claimed by a Brazilian company that is which is being funded by CAPES / FINEP in a program of R & D. Keywords: Fiber, Biomaterials, ACP.