ANALYSIS OF THE IMMUNOLOGICAL EFFICACY OF THE USE OF VITAMIN D IN PATIENTS INFECTED WITH NEW COROVAVIRUS (SARS-CoV-2) AND ALSO FOR PROPHYLATIC PURPOSES AGAINST COVID-19 INFECTION
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Revista JRG de Estudos Acadêmicos |
Texto Completo: | http://revistajrg.com/index.php/jrg/article/view/147 |
Resumo: | The novel coronavirus outbreak has triggered a rapid response from clinicians and life sciences researchers globally. Resultant advances in research show promise not only for tackling the current pandemic but also for informing future infectious disease diagnostics. We are going through a tough time. COVID-19 or SARS CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) causes pandemic in the whole world. Apart from quarantine some health measures are desperately needed to be taken as well. Mortality from COVID-19 is higher in some countries than the others. Many factors are playing essential role in this disparity including elderly people in population, general health, quality and accessibility of healthcare, socioeconomic status and most importantly Vitamin D status in the population. In this article we will be giving insights to the roles of Vitamin D in reducing respiratory tract infection, knowledge about influenza and COVID-19 epidemiology and how Vitamin D can reduce the risk. Vitamin D can reduce the risk via several mechanisms such as inducing cathelicidins and defisins which can lower the rate of viral replication, reducing pro inflammatory cytokines concentration which can injure the lining of the lungs leading to pneumonia and increasing the anti-inflammatory cytokines concentration. Vitamin D can lower the risk of COVID-19 outbreak in winter when the concentration of 25 Hydroxy Vitamin D or 25(OH) D will be lowest. Deficiency of vitamin D can cause acute respiratory distress syndrome, increase fatality rate in aged people when 25(OH) D concentration is lower. So it is required to take 10,000 IU/d of Vitamin D3 to raise 25(OH) D for few weeks followed by 5,000 IU/d. The concentration of 25(OH) D in the body should be higher than 40-60 ng/ml (100-150 nmole/L) to lower the risk of COVID-19. |
id |
JRG_6f952ab34480cccee633f6a313c30062 |
---|---|
oai_identifier_str |
oai:ojs2.revistajrg.com:article/147 |
network_acronym_str |
JRG |
network_name_str |
Revista JRG de Estudos Acadêmicos |
repository_id_str |
|
spelling |
ANALYSIS OF THE IMMUNOLOGICAL EFFICACY OF THE USE OF VITAMIN D IN PATIENTS INFECTED WITH NEW COROVAVIRUS (SARS-CoV-2) AND ALSO FOR PROPHYLATIC PURPOSES AGAINST COVID-19 INFECTIONANÁLISE DA EFICÁCIA IMUNOLÓGICA DA UTILIZAÇÃO DA VITAMINA D EM PACIENTES INFECTADOS COM NOVO COROVAVÍRUS (SARS-CoV-2) E TAMBÉM PARA FINS PROFILÁTICOS CONTRA A INFECÇÃO DE COVID-19Doenças infecciosas; situação pandêmica; COVID-19; Vitamina D; Síndrome da Dificuldade Respiratória Aguda; Pneumonia; Citocinas; Infecções do Trato Respiratório.: Infection Diseases; pandemic situation; COVID-19; Vitamin D; Acute Respiratory Distress Syndrome; Pneumonia; Cytokines; Respiratory Tract InfectionsThe novel coronavirus outbreak has triggered a rapid response from clinicians and life sciences researchers globally. Resultant advances in research show promise not only for tackling the current pandemic but also for informing future infectious disease diagnostics. We are going through a tough time. COVID-19 or SARS CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) causes pandemic in the whole world. Apart from quarantine some health measures are desperately needed to be taken as well. Mortality from COVID-19 is higher in some countries than the others. Many factors are playing essential role in this disparity including elderly people in population, general health, quality and accessibility of healthcare, socioeconomic status and most importantly Vitamin D status in the population. In this article we will be giving insights to the roles of Vitamin D in reducing respiratory tract infection, knowledge about influenza and COVID-19 epidemiology and how Vitamin D can reduce the risk. Vitamin D can reduce the risk via several mechanisms such as inducing cathelicidins and defisins which can lower the rate of viral replication, reducing pro inflammatory cytokines concentration which can injure the lining of the lungs leading to pneumonia and increasing the anti-inflammatory cytokines concentration. Vitamin D can lower the risk of COVID-19 outbreak in winter when the concentration of 25 Hydroxy Vitamin D or 25(OH) D will be lowest. Deficiency of vitamin D can cause acute respiratory distress syndrome, increase fatality rate in aged people when 25(OH) D concentration is lower. So it is required to take 10,000 IU/d of Vitamin D3 to raise 25(OH) D for few weeks followed by 5,000 IU/d. The concentration of 25(OH) D in the body should be higher than 40-60 ng/ml (100-150 nmole/L) to lower the risk of COVID-19. O novo surto de novo coronavírus (SARS-COV-2) desencadeou uma resposta rápida de médicos e pesquisadores de ciências biológicas em todo o mundo. Os avanços resultantes na pesquisa mostram-se promissores não apenas para lidar com a pandemia atual, mas também para informar futuros diagnósticos de doenças infecciosas. Estamos passando por um momento difícil. COVID-19 ou SARS CoV-2 (Síndrome Respiratória Aguda Grave Coronavírus 2) causa pandemia em todo o mundo. Além da quarentena, algumas medidas de saúde precisam ser desesperadamente tomadas também. A mortalidade por COVID-19 é mais alta em alguns países do que em outros. Muitos fatores estão desempenhando um papel essencial nessa disparidade, incluindo idosos na população, saúde geral, qualidade e acessibilidade aos cuidados de saúde, status socioeconômico e, mais importante, status de vitamina D na população. Neste artigo, daremos informações sobre os papeis da vitamina D na redução da infecção do trato respiratório, conhecimento sobre a influenza e a epidemiologia do COVID-19 e como a vitamina D pode reduzir o risco. A vitamina D pode reduzir o risco por meio de vários mecanismos, como a indução de catelicidinas e defisinas, que podem diminuir a taxa de replicação viral, reduzindo a concentração de citocinas pró-inflamatórias que podem lesar o revestimento dos pulmões, levando à pneumonia e aumentando a concentração de citocinas anti-inflamatórias. A vitamina D pode reduzir o risco de surto de COVID-19 no inverno, quando a concentração de 25 hidroxi vitamina D ou 25 (OH) D será mais baixa. A deficiência de vitamina D pode causar síndrome do desconforto respiratório agudo e aumentar a taxa de letalidade em idosos quando a concentração de 25 (OH) D é menor. Portanto, é necessário tomar 10.000 UI / d de vitamina D3 para aumentar a 25 (OH) D por algumas semanas, seguido de 5.000 UI / d. A concentração de 25 (OH) D no corpo deve ser superior a 40-60 ng / ml (100-150 nmol / L) para diminuir o risco de COVID-19.Editora JRG2020-12-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigo avaliado pelos Paresapplication/pdfhttp://revistajrg.com/index.php/jrg/article/view/14710.5281/zenodo.4361677JRG Journal of Academic Studies; Vol. 3 No. 7 (2020): Revista JRG de Estudos Acadêmicos; 718-747JRG Journal of Academic Studies ; Vol. 3 Núm. 7 (2020): Revista JRG de Estudos Acadêmicos; 718-747JRG Journal of Academic Studies; V. 3 N. 7 (2020): Revista JRG de Estudos Acadêmicos; 718-747Revista JRG de Estudos Acadêmicos ; v. 3 n. 7 (2020): Revista JRG de Estudos Acadêmicos; 718-7472595-1661reponame:Revista JRG de Estudos Acadêmicosinstname:Editora JRGinstacron:JRGporenghttp://revistajrg.com/index.php/jrg/article/view/147/242http://revistajrg.com/index.php/jrg/article/view/147/243https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCruz, Ananias Alves Moura, Johnson Pontes de Dantas, Ranni Pereira Santos 2020-12-18T22:06:19Zoai:ojs2.revistajrg.com:article/147Revistahttp://revistajrg.com/index.php/jrgPRIhttp://revistajrg.com/index.php/jrg/oaiprofessorjonas@gmail.com||2595-16612595-1661opendoar:2020-12-18T22:06:19Revista JRG de Estudos Acadêmicos - Editora JRGfalse |
dc.title.none.fl_str_mv |
ANALYSIS OF THE IMMUNOLOGICAL EFFICACY OF THE USE OF VITAMIN D IN PATIENTS INFECTED WITH NEW COROVAVIRUS (SARS-CoV-2) AND ALSO FOR PROPHYLATIC PURPOSES AGAINST COVID-19 INFECTION ANÁLISE DA EFICÁCIA IMUNOLÓGICA DA UTILIZAÇÃO DA VITAMINA D EM PACIENTES INFECTADOS COM NOVO COROVAVÍRUS (SARS-CoV-2) E TAMBÉM PARA FINS PROFILÁTICOS CONTRA A INFECÇÃO DE COVID-19 |
title |
ANALYSIS OF THE IMMUNOLOGICAL EFFICACY OF THE USE OF VITAMIN D IN PATIENTS INFECTED WITH NEW COROVAVIRUS (SARS-CoV-2) AND ALSO FOR PROPHYLATIC PURPOSES AGAINST COVID-19 INFECTION |
spellingShingle |
ANALYSIS OF THE IMMUNOLOGICAL EFFICACY OF THE USE OF VITAMIN D IN PATIENTS INFECTED WITH NEW COROVAVIRUS (SARS-CoV-2) AND ALSO FOR PROPHYLATIC PURPOSES AGAINST COVID-19 INFECTION Cruz, Ananias Alves Doenças infecciosas; situação pandêmica; COVID-19; Vitamina D; Síndrome da Dificuldade Respiratória Aguda; Pneumonia; Citocinas; Infecções do Trato Respiratório. : Infection Diseases; pandemic situation; COVID-19; Vitamin D; Acute Respiratory Distress Syndrome; Pneumonia; Cytokines; Respiratory Tract Infections |
title_short |
ANALYSIS OF THE IMMUNOLOGICAL EFFICACY OF THE USE OF VITAMIN D IN PATIENTS INFECTED WITH NEW COROVAVIRUS (SARS-CoV-2) AND ALSO FOR PROPHYLATIC PURPOSES AGAINST COVID-19 INFECTION |
title_full |
ANALYSIS OF THE IMMUNOLOGICAL EFFICACY OF THE USE OF VITAMIN D IN PATIENTS INFECTED WITH NEW COROVAVIRUS (SARS-CoV-2) AND ALSO FOR PROPHYLATIC PURPOSES AGAINST COVID-19 INFECTION |
title_fullStr |
ANALYSIS OF THE IMMUNOLOGICAL EFFICACY OF THE USE OF VITAMIN D IN PATIENTS INFECTED WITH NEW COROVAVIRUS (SARS-CoV-2) AND ALSO FOR PROPHYLATIC PURPOSES AGAINST COVID-19 INFECTION |
title_full_unstemmed |
ANALYSIS OF THE IMMUNOLOGICAL EFFICACY OF THE USE OF VITAMIN D IN PATIENTS INFECTED WITH NEW COROVAVIRUS (SARS-CoV-2) AND ALSO FOR PROPHYLATIC PURPOSES AGAINST COVID-19 INFECTION |
title_sort |
ANALYSIS OF THE IMMUNOLOGICAL EFFICACY OF THE USE OF VITAMIN D IN PATIENTS INFECTED WITH NEW COROVAVIRUS (SARS-CoV-2) AND ALSO FOR PROPHYLATIC PURPOSES AGAINST COVID-19 INFECTION |
author |
Cruz, Ananias Alves |
author_facet |
Cruz, Ananias Alves Moura, Johnson Pontes de Dantas, Ranni Pereira Santos |
author_role |
author |
author2 |
Moura, Johnson Pontes de Dantas, Ranni Pereira Santos |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Cruz, Ananias Alves Moura, Johnson Pontes de Dantas, Ranni Pereira Santos |
dc.subject.por.fl_str_mv |
Doenças infecciosas; situação pandêmica; COVID-19; Vitamina D; Síndrome da Dificuldade Respiratória Aguda; Pneumonia; Citocinas; Infecções do Trato Respiratório. : Infection Diseases; pandemic situation; COVID-19; Vitamin D; Acute Respiratory Distress Syndrome; Pneumonia; Cytokines; Respiratory Tract Infections |
topic |
Doenças infecciosas; situação pandêmica; COVID-19; Vitamina D; Síndrome da Dificuldade Respiratória Aguda; Pneumonia; Citocinas; Infecções do Trato Respiratório. : Infection Diseases; pandemic situation; COVID-19; Vitamin D; Acute Respiratory Distress Syndrome; Pneumonia; Cytokines; Respiratory Tract Infections |
description |
The novel coronavirus outbreak has triggered a rapid response from clinicians and life sciences researchers globally. Resultant advances in research show promise not only for tackling the current pandemic but also for informing future infectious disease diagnostics. We are going through a tough time. COVID-19 or SARS CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) causes pandemic in the whole world. Apart from quarantine some health measures are desperately needed to be taken as well. Mortality from COVID-19 is higher in some countries than the others. Many factors are playing essential role in this disparity including elderly people in population, general health, quality and accessibility of healthcare, socioeconomic status and most importantly Vitamin D status in the population. In this article we will be giving insights to the roles of Vitamin D in reducing respiratory tract infection, knowledge about influenza and COVID-19 epidemiology and how Vitamin D can reduce the risk. Vitamin D can reduce the risk via several mechanisms such as inducing cathelicidins and defisins which can lower the rate of viral replication, reducing pro inflammatory cytokines concentration which can injure the lining of the lungs leading to pneumonia and increasing the anti-inflammatory cytokines concentration. Vitamin D can lower the risk of COVID-19 outbreak in winter when the concentration of 25 Hydroxy Vitamin D or 25(OH) D will be lowest. Deficiency of vitamin D can cause acute respiratory distress syndrome, increase fatality rate in aged people when 25(OH) D concentration is lower. So it is required to take 10,000 IU/d of Vitamin D3 to raise 25(OH) D for few weeks followed by 5,000 IU/d. The concentration of 25(OH) D in the body should be higher than 40-60 ng/ml (100-150 nmole/L) to lower the risk of COVID-19. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo avaliado pelos Pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://revistajrg.com/index.php/jrg/article/view/147 10.5281/zenodo.4361677 |
url |
http://revistajrg.com/index.php/jrg/article/view/147 |
identifier_str_mv |
10.5281/zenodo.4361677 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
http://revistajrg.com/index.php/jrg/article/view/147/242 http://revistajrg.com/index.php/jrg/article/view/147/243 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Editora JRG |
publisher.none.fl_str_mv |
Editora JRG |
dc.source.none.fl_str_mv |
JRG Journal of Academic Studies; Vol. 3 No. 7 (2020): Revista JRG de Estudos Acadêmicos; 718-747 JRG Journal of Academic Studies ; Vol. 3 Núm. 7 (2020): Revista JRG de Estudos Acadêmicos; 718-747 JRG Journal of Academic Studies; V. 3 N. 7 (2020): Revista JRG de Estudos Acadêmicos; 718-747 Revista JRG de Estudos Acadêmicos ; v. 3 n. 7 (2020): Revista JRG de Estudos Acadêmicos; 718-747 2595-1661 reponame:Revista JRG de Estudos Acadêmicos instname:Editora JRG instacron:JRG |
instname_str |
Editora JRG |
instacron_str |
JRG |
institution |
JRG |
reponame_str |
Revista JRG de Estudos Acadêmicos |
collection |
Revista JRG de Estudos Acadêmicos |
repository.name.fl_str_mv |
Revista JRG de Estudos Acadêmicos - Editora JRG |
repository.mail.fl_str_mv |
professorjonas@gmail.com|| |
_version_ |
1797068984348049408 |