Memory tests are not good predictors of surgical outcome in patients with mesial temporal Lobe epilepsy associated with hippocampal sclerosis
Autor(a) principal: | |
---|---|
Data de Publicação: | 2005 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of epilepsy and clinical neurophysiology (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-26492005000300003 |
Resumo: | Introduction: One of the objectives of pre-surgical evaluation in mesial temporal epilepsy associated to hippoocampal sclerosis is the identification of patients with bad surgical prognosis for seizure control. At least theoretically, neuropsychological tests could be used in this venue. Objective: To evaluate whether verbal and visual memory tests can be used as isolate predictors of the post-surgical seizure outcome in patients with mesial temporal lobe epilepsy associated with hippocampal sclerosis refractory to pharmacological treatment. Methods: In a retrospective cohort study using the control of epileptic seizures as end-point, we evaluated 187 patients and calculated the correlation of clinical variables, cognitive evaluation, neuroimaging data, demographic data and electrophysiological findings with the result of seizure control after lobectomy in these patients. Results: An unfavorable prognosis during the postoperative period was observed only in association with low visual reproduction scores (visual memory). However, after Bonferroni correction, which was necessary to reduce the chance of type I error, this result was found to be spurious. Conclusion: We conclude that neuropsychological tests of verbal and visual memory such as those used in the routine presurgical evaluation of our patients with temporal lobe epilepsy are not good isolated predictors of surgical outcome. |
id |
LBE-1_31ea829393bf903e97f100784ec1213b |
---|---|
oai_identifier_str |
oai:scielo:S1676-26492005000300003 |
network_acronym_str |
LBE-1 |
network_name_str |
Journal of epilepsy and clinical neurophysiology (Online) |
repository_id_str |
|
spelling |
Memory tests are not good predictors of surgical outcome in patients with mesial temporal Lobe epilepsy associated with hippocampal sclerosistemporal lobectomycognitive testsepilepsyevolutionIntroduction: One of the objectives of pre-surgical evaluation in mesial temporal epilepsy associated to hippoocampal sclerosis is the identification of patients with bad surgical prognosis for seizure control. At least theoretically, neuropsychological tests could be used in this venue. Objective: To evaluate whether verbal and visual memory tests can be used as isolate predictors of the post-surgical seizure outcome in patients with mesial temporal lobe epilepsy associated with hippocampal sclerosis refractory to pharmacological treatment. Methods: In a retrospective cohort study using the control of epileptic seizures as end-point, we evaluated 187 patients and calculated the correlation of clinical variables, cognitive evaluation, neuroimaging data, demographic data and electrophysiological findings with the result of seizure control after lobectomy in these patients. Results: An unfavorable prognosis during the postoperative period was observed only in association with low visual reproduction scores (visual memory). However, after Bonferroni correction, which was necessary to reduce the chance of type I error, this result was found to be spurious. Conclusion: We conclude that neuropsychological tests of verbal and visual memory such as those used in the routine presurgical evaluation of our patients with temporal lobe epilepsy are not good isolated predictors of surgical outcome.Liga Brasileira de Epilepsia (LBE)2005-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-26492005000300003Journal of Epilepsy and Clinical Neurophysiology v.11 n.3 2005reponame:Journal of epilepsy and clinical neurophysiology (Online)instname:Liga Brasileira de Epilepsia (LBE)instacron:LBE10.1590/S1676-26492005000300003info:eu-repo/semantics/openAccessEscorsi-Rosset,SaraBianchin,M Marino.Walz,RogerTerra-Bustamante,Vera C.Carlotti Jr.,Carlos G.Assirati Jr.,João A.Santos,Antonio C.Sakamoto,Américo C.eng2012-06-06T00:00:00Zoai:scielo:S1676-26492005000300003Revistahttp://epilepsia.org.br/publicacoes/ONGhttps://old.scielo.br/oai/scielo-oai.php||jecnpoa@terra.com.br1980-53651676-2649opendoar:2012-06-06T00:00Journal of epilepsy and clinical neurophysiology (Online) - Liga Brasileira de Epilepsia (LBE)false |
dc.title.none.fl_str_mv |
Memory tests are not good predictors of surgical outcome in patients with mesial temporal Lobe epilepsy associated with hippocampal sclerosis |
title |
Memory tests are not good predictors of surgical outcome in patients with mesial temporal Lobe epilepsy associated with hippocampal sclerosis |
spellingShingle |
Memory tests are not good predictors of surgical outcome in patients with mesial temporal Lobe epilepsy associated with hippocampal sclerosis Escorsi-Rosset,Sara temporal lobectomy cognitive tests epilepsy evolution |
title_short |
Memory tests are not good predictors of surgical outcome in patients with mesial temporal Lobe epilepsy associated with hippocampal sclerosis |
title_full |
Memory tests are not good predictors of surgical outcome in patients with mesial temporal Lobe epilepsy associated with hippocampal sclerosis |
title_fullStr |
Memory tests are not good predictors of surgical outcome in patients with mesial temporal Lobe epilepsy associated with hippocampal sclerosis |
title_full_unstemmed |
Memory tests are not good predictors of surgical outcome in patients with mesial temporal Lobe epilepsy associated with hippocampal sclerosis |
title_sort |
Memory tests are not good predictors of surgical outcome in patients with mesial temporal Lobe epilepsy associated with hippocampal sclerosis |
author |
Escorsi-Rosset,Sara |
author_facet |
Escorsi-Rosset,Sara Bianchin,M Marino. Walz,Roger Terra-Bustamante,Vera C. Carlotti Jr.,Carlos G. Assirati Jr.,João A. Santos,Antonio C. Sakamoto,Américo C. |
author_role |
author |
author2 |
Bianchin,M Marino. Walz,Roger Terra-Bustamante,Vera C. Carlotti Jr.,Carlos G. Assirati Jr.,João A. Santos,Antonio C. Sakamoto,Américo C. |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Escorsi-Rosset,Sara Bianchin,M Marino. Walz,Roger Terra-Bustamante,Vera C. Carlotti Jr.,Carlos G. Assirati Jr.,João A. Santos,Antonio C. Sakamoto,Américo C. |
dc.subject.por.fl_str_mv |
temporal lobectomy cognitive tests epilepsy evolution |
topic |
temporal lobectomy cognitive tests epilepsy evolution |
description |
Introduction: One of the objectives of pre-surgical evaluation in mesial temporal epilepsy associated to hippoocampal sclerosis is the identification of patients with bad surgical prognosis for seizure control. At least theoretically, neuropsychological tests could be used in this venue. Objective: To evaluate whether verbal and visual memory tests can be used as isolate predictors of the post-surgical seizure outcome in patients with mesial temporal lobe epilepsy associated with hippocampal sclerosis refractory to pharmacological treatment. Methods: In a retrospective cohort study using the control of epileptic seizures as end-point, we evaluated 187 patients and calculated the correlation of clinical variables, cognitive evaluation, neuroimaging data, demographic data and electrophysiological findings with the result of seizure control after lobectomy in these patients. Results: An unfavorable prognosis during the postoperative period was observed only in association with low visual reproduction scores (visual memory). However, after Bonferroni correction, which was necessary to reduce the chance of type I error, this result was found to be spurious. Conclusion: We conclude that neuropsychological tests of verbal and visual memory such as those used in the routine presurgical evaluation of our patients with temporal lobe epilepsy are not good isolated predictors of surgical outcome. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-26492005000300003 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-26492005000300003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1676-26492005000300003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Liga Brasileira de Epilepsia (LBE) |
publisher.none.fl_str_mv |
Liga Brasileira de Epilepsia (LBE) |
dc.source.none.fl_str_mv |
Journal of Epilepsy and Clinical Neurophysiology v.11 n.3 2005 reponame:Journal of epilepsy and clinical neurophysiology (Online) instname:Liga Brasileira de Epilepsia (LBE) instacron:LBE |
instname_str |
Liga Brasileira de Epilepsia (LBE) |
instacron_str |
LBE |
institution |
LBE |
reponame_str |
Journal of epilepsy and clinical neurophysiology (Online) |
collection |
Journal of epilepsy and clinical neurophysiology (Online) |
repository.name.fl_str_mv |
Journal of epilepsy and clinical neurophysiology (Online) - Liga Brasileira de Epilepsia (LBE) |
repository.mail.fl_str_mv |
||jecnpoa@terra.com.br |
_version_ |
1754734659037560832 |