Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | MedicalExpress (São Paulo. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2358-04292016000500001 |
Resumo: | OBJECTIVE: Cognitive Behavioral Therapy (CBT) has been recommended by several international guidelines as the gold-standard treatment to address the needs of patients with schizophrenia. This review provides an overview on recent advances regarding CBT for schizophrenia. METHODS: An electronic search was performed on PubMed/MEDLINE, Web of Science and Cochrane Database, using the key-words: "schizophrenia", "psychosis", "cognitive-behavioral therapy", "CBT" and "psychotherapy". RESULTS: Numerous systematic reviews support the immediate and long-term efficacy of Cognitive Behavioral Therapy to reduce positive and negative symptoms in patients with schizophrenia. In the last decade, CBT for schizophrenia has been applied to clinical high-risk subjects and delivered using innovative approaches (low intensity, web-based and self-guided). Brain regions and networks which support high-level cognitive functions have been associated with CBT responsiveness. There is preliminary evidence indicating that CBT induces a prefrontal dependent increase in the top-down modulation of social threat activation. CONCLUSION: In the last decade, CBT for schizophrenia has explored new treatment outcomes, targeted acute and pre-clinical populations and provided alternative methods to reach more patients and reduce intervention costs. The patients' neurocognitive profile seems to play a critical role in treatment response and combining CBT with cognitive remediation may allow to enhance therapeutic effects. Although CBT for schizophrenia is widely established as a gold-standard practice, future studies using innovative CBT protocols, exploring brain-related predictors and treatment outcomes may allow this intervention to be more effective, personalized and to reach a wider number of patients. |
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Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findingsCognitive-behavioral therapySchizophreniaPsychosisNeurobiologicalNeuroplasticity OBJECTIVE: Cognitive Behavioral Therapy (CBT) has been recommended by several international guidelines as the gold-standard treatment to address the needs of patients with schizophrenia. This review provides an overview on recent advances regarding CBT for schizophrenia. METHODS: An electronic search was performed on PubMed/MEDLINE, Web of Science and Cochrane Database, using the key-words: "schizophrenia", "psychosis", "cognitive-behavioral therapy", "CBT" and "psychotherapy". RESULTS: Numerous systematic reviews support the immediate and long-term efficacy of Cognitive Behavioral Therapy to reduce positive and negative symptoms in patients with schizophrenia. In the last decade, CBT for schizophrenia has been applied to clinical high-risk subjects and delivered using innovative approaches (low intensity, web-based and self-guided). Brain regions and networks which support high-level cognitive functions have been associated with CBT responsiveness. There is preliminary evidence indicating that CBT induces a prefrontal dependent increase in the top-down modulation of social threat activation. CONCLUSION: In the last decade, CBT for schizophrenia has explored new treatment outcomes, targeted acute and pre-clinical populations and provided alternative methods to reach more patients and reduce intervention costs. The patients' neurocognitive profile seems to play a critical role in treatment response and combining CBT with cognitive remediation may allow to enhance therapeutic effects. Although CBT for schizophrenia is widely established as a gold-standard practice, future studies using innovative CBT protocols, exploring brain-related predictors and treatment outcomes may allow this intervention to be more effective, personalized and to reach a wider number of patients.Mavera Edições Técnicas e Científicas Ltda2016-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2358-04292016000500001MedicalExpress v.3 n.5 2016reponame:MedicalExpress (São Paulo. Online)instname:Mavera Edições Científicas e Técnicas Ltda-MEinstacron:METC10.5935/MedicalExpress.2016.05.01info:eu-repo/semantics/openAccessCandida,MaristelaCampos,CarlosMonteiro,BárbaraRocha,Nuno Barbosa F.Paes,FláviaNardi,António EgídioMachado,Sérgioeng2016-11-04T00:00:00Zoai:scielo:S2358-04292016000500001Revistahttp://www.medicalexpress.net.brhttps://old.scielo.br/oai/scielo-oai.php||medicalexpress@me.net.br2358-04292318-8111opendoar:2016-11-04T00:00MedicalExpress (São Paulo. Online) - Mavera Edições Científicas e Técnicas Ltda-MEfalse |
dc.title.none.fl_str_mv |
Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings |
title |
Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings |
spellingShingle |
Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings Candida,Maristela Cognitive-behavioral therapy Schizophrenia Psychosis Neurobiological Neuroplasticity |
title_short |
Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings |
title_full |
Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings |
title_fullStr |
Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings |
title_full_unstemmed |
Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings |
title_sort |
Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings |
author |
Candida,Maristela |
author_facet |
Candida,Maristela Campos,Carlos Monteiro,Bárbara Rocha,Nuno Barbosa F. Paes,Flávia Nardi,António Egídio Machado,Sérgio |
author_role |
author |
author2 |
Campos,Carlos Monteiro,Bárbara Rocha,Nuno Barbosa F. Paes,Flávia Nardi,António Egídio Machado,Sérgio |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Candida,Maristela Campos,Carlos Monteiro,Bárbara Rocha,Nuno Barbosa F. Paes,Flávia Nardi,António Egídio Machado,Sérgio |
dc.subject.por.fl_str_mv |
Cognitive-behavioral therapy Schizophrenia Psychosis Neurobiological Neuroplasticity |
topic |
Cognitive-behavioral therapy Schizophrenia Psychosis Neurobiological Neuroplasticity |
description |
OBJECTIVE: Cognitive Behavioral Therapy (CBT) has been recommended by several international guidelines as the gold-standard treatment to address the needs of patients with schizophrenia. This review provides an overview on recent advances regarding CBT for schizophrenia. METHODS: An electronic search was performed on PubMed/MEDLINE, Web of Science and Cochrane Database, using the key-words: "schizophrenia", "psychosis", "cognitive-behavioral therapy", "CBT" and "psychotherapy". RESULTS: Numerous systematic reviews support the immediate and long-term efficacy of Cognitive Behavioral Therapy to reduce positive and negative symptoms in patients with schizophrenia. In the last decade, CBT for schizophrenia has been applied to clinical high-risk subjects and delivered using innovative approaches (low intensity, web-based and self-guided). Brain regions and networks which support high-level cognitive functions have been associated with CBT responsiveness. There is preliminary evidence indicating that CBT induces a prefrontal dependent increase in the top-down modulation of social threat activation. CONCLUSION: In the last decade, CBT for schizophrenia has explored new treatment outcomes, targeted acute and pre-clinical populations and provided alternative methods to reach more patients and reduce intervention costs. The patients' neurocognitive profile seems to play a critical role in treatment response and combining CBT with cognitive remediation may allow to enhance therapeutic effects. Although CBT for schizophrenia is widely established as a gold-standard practice, future studies using innovative CBT protocols, exploring brain-related predictors and treatment outcomes may allow this intervention to be more effective, personalized and to reach a wider number of patients. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2358-04292016000500001 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2358-04292016000500001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/MedicalExpress.2016.05.01 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Mavera Edições Técnicas e Científicas Ltda |
publisher.none.fl_str_mv |
Mavera Edições Técnicas e Científicas Ltda |
dc.source.none.fl_str_mv |
MedicalExpress v.3 n.5 2016 reponame:MedicalExpress (São Paulo. Online) instname:Mavera Edições Científicas e Técnicas Ltda-ME instacron:METC |
instname_str |
Mavera Edições Científicas e Técnicas Ltda-ME |
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METC |
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METC |
reponame_str |
MedicalExpress (São Paulo. Online) |
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MedicalExpress (São Paulo. Online) |
repository.name.fl_str_mv |
MedicalExpress (São Paulo. Online) - Mavera Edições Científicas e Técnicas Ltda-ME |
repository.mail.fl_str_mv |
||medicalexpress@me.net.br |
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