Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da Uninove |
Texto Completo: | http://bibliotecatede.uninove.br/handle/tede/2614 |
Resumo: | The association between oral health and chronic obstructive pulmonary disease (COPD) has been widely studied and the aspiration of microorganisms is one of the most accepted mechanisms for pulmonary exacerbation. Bronchiectasis has many clinical similarities with COPD, such increased morbidity and decreased quality of life. However, the oral health of these patients has not yet been studied to date. Since halitosis has been reported in these patients and the decrease in oral microbial load may contribute to the reduction of these exacerbations, the objective of this study was to evaluate the clinical effect of PDT in the treatment of halitosis in bronchiectasis patients, to assess oral health conditions and quality of life in this population. The study was divided into two phases: (1) 163 bronchiectasis and 163 healthy patients matched by gender, age and socioeconomic status were recruited. The clinical and periodontal examination and its classification were done through the Third National Health and Nutrition Examination Survey. Two quality of life instruments were applied: OHIP-14 and Saint George's Respiratory Questionnaire (SGRQ). In phase (2), the clinical effect of PDT was evaluated in both groups diagnosed with halitosis by gas chromatography in three phases (a) baseline, (b) after PDT (c) after periodontal treatment. The prevalence and severity of periodontal disease were higher in the BQT group (p <0.05) and all patients who had exacerbated in the last 3 months had periodontal disease. Out of the bronchiectasis patients, 50% report that the disease generates negative impacts on their quality of life. Therefore, it is concluded that PDT was effective in the treatment of halitosis in bronchiectasis patients. Bronchiectasis patients have poor oral health status and high prevalence of periodontal disease. |
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Horliana, Anna Carolina Ratto Tempestinihttp://lattes.cnpq.br/0442315483134442Stelmach, Rafaelhttp://lattes.cnpq.br/3399245674893240Horliana, Anna Carolina Ratto Tempestinihttp://lattes.cnpq.br/0442315483134442Bussadori, Sandra Kalilhttp://lattes.cnpq.br/4110914499694913Peixoto, Isabel de Freitashttp://lattes.cnpq.br/6925881097345555http://lattes.cnpq.br/0460828953676596Pinto, Erika Horácio2021-10-22T23:25:18Z2016-12-19Pinto, Erika Horácio. Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos. 2016. 62 f. Dissertação( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo.http://bibliotecatede.uninove.br/handle/tede/2614The association between oral health and chronic obstructive pulmonary disease (COPD) has been widely studied and the aspiration of microorganisms is one of the most accepted mechanisms for pulmonary exacerbation. Bronchiectasis has many clinical similarities with COPD, such increased morbidity and decreased quality of life. However, the oral health of these patients has not yet been studied to date. Since halitosis has been reported in these patients and the decrease in oral microbial load may contribute to the reduction of these exacerbations, the objective of this study was to evaluate the clinical effect of PDT in the treatment of halitosis in bronchiectasis patients, to assess oral health conditions and quality of life in this population. The study was divided into two phases: (1) 163 bronchiectasis and 163 healthy patients matched by gender, age and socioeconomic status were recruited. The clinical and periodontal examination and its classification were done through the Third National Health and Nutrition Examination Survey. Two quality of life instruments were applied: OHIP-14 and Saint George's Respiratory Questionnaire (SGRQ). In phase (2), the clinical effect of PDT was evaluated in both groups diagnosed with halitosis by gas chromatography in three phases (a) baseline, (b) after PDT (c) after periodontal treatment. The prevalence and severity of periodontal disease were higher in the BQT group (p <0.05) and all patients who had exacerbated in the last 3 months had periodontal disease. Out of the bronchiectasis patients, 50% report that the disease generates negative impacts on their quality of life. Therefore, it is concluded that PDT was effective in the treatment of halitosis in bronchiectasis patients. Bronchiectasis patients have poor oral health status and high prevalence of periodontal disease.A associação entre saúde oral e a doença pulmonar obstrutiva crônica (DPOC) tem sido muito estudada e a aspiração de microrganismos é um dos mecanismos mais aceitos para a exacerbação pulmonar. A bronquiectasia possui muitas semelhanças clínicas com a DPOC, mas até o momento a saúde oral desses pacientes ainda não foi estudada. Tendo em vista que a halitose tem sido relatada nesses pacientes e que a diminuição da carga microbiana oral pode contribuir para a diminuição dessas exacerbações, o objetivo deste estudo foi avaliar o efeito clínico da terapia fotodinâmica (PDT) no tratamento da halitose em pacientes bronquiectásicos (BQT), avaliar sua condição de saúde oral e qualidade de vida. O estudo foi dividido em duas fases: (1) grupo 1 - 163 pacientes bronquiectásicos e grupo 2 - 163 saudáveis pareados por gênero, idade e nível socioeconômico. Foi realizado exame clinico e periodontal e aplicados dois instrumentos de avaliação: OHIP-14 e Saint George`s Respiratory Questionnaire (SGRQ). Na fase (2) foi avaliado o efeito clínico da PDT em ambos os grupos diagnosticados com halitose por meio de cromatografia gasosa em três fases (a) baseline, (b) após PDT e (c) após tratamento periodontal. A prevalência e a severidade da doença periodontal (DP) foram maiores no grupo BQT (p<0,05), sendo que os pacientes que mais exacerbaram nos últimos 3 meses apresentam DP. Dos bronquiectásicos, 50% relatam que a doença gera impactos negativos sobre sua qualidade de vida. Portanto conclui-se que a PDT não foi efetiva no tratamento da halitose em pacientes bronquiectásicos, também possuem pior condição de saúde oral e alta prevalência de DP.Submitted by Nadir Basilio (nadirsb@uninove.br) on 2021-10-22T23:25:18Z No. of bitstreams: 1 Erika Horacio Pinto.pdf: 2703966 bytes, checksum: 51df1ce6fc21f3aedc069ded7b9d1223 (MD5)Made available in DSpace on 2021-10-22T23:25:18Z (GMT). No. of bitstreams: 1 Erika Horacio Pinto.pdf: 2703966 bytes, checksum: 51df1ce6fc21f3aedc069ded7b9d1223 (MD5) Previous issue date: 2016-12-19application/pdfporUniversidade Nove de JulhoPrograma de Pós-Graduação em Biofotônica Aplicada às Ciências da SaúdeUNINOVEBrasilSaúdehalitoseterapia fotodinâmicadoença periodontalbronquiectasiaprevalênciahalitosisphotodynamic therapyperiodontal diseasesbronchiectasisprevalenceCIENCIAS DA SAUDEEnsaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicosRandomized controlled clinical test of halitosis treatment with photodynamic therapy in broinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALErika Horacio Pinto.pdfErika Horacio Pinto.pdfapplication/pdf2703966http://localhost:8080/tede/bitstream/tede/2614/2/Erika+Horacio+Pinto.pdf51df1ce6fc21f3aedc069ded7b9d1223MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/2614/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/26142021-10-22 21:25:18.931oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2021-10-22T23:25:18Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false |
dc.title.por.fl_str_mv |
Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos |
dc.title.alternative.eng.fl_str_mv |
Randomized controlled clinical test of halitosis treatment with photodynamic therapy in bro |
title |
Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos |
spellingShingle |
Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos Pinto, Erika Horácio halitose terapia fotodinâmica doença periodontal bronquiectasia prevalência halitosis photodynamic therapy periodontal diseases bronchiectasis prevalence CIENCIAS DA SAUDE |
title_short |
Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos |
title_full |
Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos |
title_fullStr |
Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos |
title_full_unstemmed |
Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos |
title_sort |
Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos |
author |
Pinto, Erika Horácio |
author_facet |
Pinto, Erika Horácio |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Horliana, Anna Carolina Ratto Tempestini |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/0442315483134442 |
dc.contributor.advisor-co1.fl_str_mv |
Stelmach, Rafael |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/3399245674893240 |
dc.contributor.referee1.fl_str_mv |
Horliana, Anna Carolina Ratto Tempestini |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/0442315483134442 |
dc.contributor.referee2.fl_str_mv |
Bussadori, Sandra Kalil |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/4110914499694913 |
dc.contributor.referee3.fl_str_mv |
Peixoto, Isabel de Freitas |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/6925881097345555 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/0460828953676596 |
dc.contributor.author.fl_str_mv |
Pinto, Erika Horácio |
contributor_str_mv |
Horliana, Anna Carolina Ratto Tempestini Stelmach, Rafael Horliana, Anna Carolina Ratto Tempestini Bussadori, Sandra Kalil Peixoto, Isabel de Freitas |
dc.subject.por.fl_str_mv |
halitose terapia fotodinâmica doença periodontal bronquiectasia prevalência |
topic |
halitose terapia fotodinâmica doença periodontal bronquiectasia prevalência halitosis photodynamic therapy periodontal diseases bronchiectasis prevalence CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
halitosis photodynamic therapy periodontal diseases bronchiectasis prevalence |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
The association between oral health and chronic obstructive pulmonary disease (COPD) has been widely studied and the aspiration of microorganisms is one of the most accepted mechanisms for pulmonary exacerbation. Bronchiectasis has many clinical similarities with COPD, such increased morbidity and decreased quality of life. However, the oral health of these patients has not yet been studied to date. Since halitosis has been reported in these patients and the decrease in oral microbial load may contribute to the reduction of these exacerbations, the objective of this study was to evaluate the clinical effect of PDT in the treatment of halitosis in bronchiectasis patients, to assess oral health conditions and quality of life in this population. The study was divided into two phases: (1) 163 bronchiectasis and 163 healthy patients matched by gender, age and socioeconomic status were recruited. The clinical and periodontal examination and its classification were done through the Third National Health and Nutrition Examination Survey. Two quality of life instruments were applied: OHIP-14 and Saint George's Respiratory Questionnaire (SGRQ). In phase (2), the clinical effect of PDT was evaluated in both groups diagnosed with halitosis by gas chromatography in three phases (a) baseline, (b) after PDT (c) after periodontal treatment. The prevalence and severity of periodontal disease were higher in the BQT group (p <0.05) and all patients who had exacerbated in the last 3 months had periodontal disease. Out of the bronchiectasis patients, 50% report that the disease generates negative impacts on their quality of life. Therefore, it is concluded that PDT was effective in the treatment of halitosis in bronchiectasis patients. Bronchiectasis patients have poor oral health status and high prevalence of periodontal disease. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016-12-19 |
dc.date.accessioned.fl_str_mv |
2021-10-22T23:25:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/masterThesis |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
Pinto, Erika Horácio. Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos. 2016. 62 f. Dissertação( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo. |
dc.identifier.uri.fl_str_mv |
http://bibliotecatede.uninove.br/handle/tede/2614 |
identifier_str_mv |
Pinto, Erika Horácio. Ensaio clínico controlado aleatorizado do tratamento da halitose com terapia fotodinâmica em pacientes bronquiectásicos. 2016. 62 f. Dissertação( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo. |
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http://bibliotecatede.uninove.br/handle/tede/2614 |
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