Tratamento da acne vulgar com luz azul: uma revisão sistemática
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da Uninove |
Texto Completo: | http://bibliotecatede.uninove.br/handle/tede/2623 |
Resumo: | Acne treatment is commonly performed with retinoids, such as adapalene, retinoic acid, isotretinoin, which have anti-comedogenic, anti-inflammatory , and comedolytic characteristics. The main disadvantage of most topical retinoids is related to cutaneous side effects. Acne usually improves after exposure to sunlight or artificially produced UV radiation. This research aimed to analyze the use of blue light for the treatment of inflammatory acne. A systematic literature review was carried out, whose research protocol followed the PRISMA recommendation, and randomized clinical trial studies that compared blue light with another intervention as a control were included in the sample. The search was carried out in the PUBMED and WEB of SCIENCE databases, combining the terms "photobiomodulation", "Acne", "LLLT", Phototherapy, "LED" and "blue light". The methodological quality of the included studies was assessed using the Cochrane Collaboration Risk of Bias Scale. After excluding duplicates, the titles, and abstracts of 81 articles were evaluated, and 50 articles were selected for full reading, including 8 articles in the review at the end. For this purpose, articles were selected from 1990 to 2021. Eight randomized controlled clinical trials were analyzed using blue light and a comparative method. Most studies compared the use of blue light with benzoyl peroxide, and the others used another light source or placebo as a comparison. The included studies differed from each other regarding the protocol applied with blue light. The studies showed significant improvements in the general picture of acne with blue light, considering the number and size of lesions, and as for inflammation, red light showed better results. It is concluded that despite the great potential in its use in the treatment of acne, there is a need for more detailed tests on the effect of blue light in this treatment. |
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Motta, Lara Jansiskihttp://lattes.cnpq.br/6750462252900819Motta, Lara Jansiskihttp://lattes.cnpq.br/6750462252900819Pavani, Christianehttp://lattes.cnpq.br/2148910222765744Fonseca, Elsa Susana ReisDiogo, Mara Lúcia Gonçalves2021-10-26T20:22:39Z2021-06-17Diogo, Mara Lúcia Gonçalves. Tratamento da acne vulgar com luz azul: uma revisão sistemática. 2021. 43 f. Dissertação( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo.http://bibliotecatede.uninove.br/handle/tede/2623Acne treatment is commonly performed with retinoids, such as adapalene, retinoic acid, isotretinoin, which have anti-comedogenic, anti-inflammatory , and comedolytic characteristics. The main disadvantage of most topical retinoids is related to cutaneous side effects. Acne usually improves after exposure to sunlight or artificially produced UV radiation. This research aimed to analyze the use of blue light for the treatment of inflammatory acne. A systematic literature review was carried out, whose research protocol followed the PRISMA recommendation, and randomized clinical trial studies that compared blue light with another intervention as a control were included in the sample. The search was carried out in the PUBMED and WEB of SCIENCE databases, combining the terms "photobiomodulation", "Acne", "LLLT", Phototherapy, "LED" and "blue light". The methodological quality of the included studies was assessed using the Cochrane Collaboration Risk of Bias Scale. After excluding duplicates, the titles, and abstracts of 81 articles were evaluated, and 50 articles were selected for full reading, including 8 articles in the review at the end. For this purpose, articles were selected from 1990 to 2021. Eight randomized controlled clinical trials were analyzed using blue light and a comparative method. Most studies compared the use of blue light with benzoyl peroxide, and the others used another light source or placebo as a comparison. The included studies differed from each other regarding the protocol applied with blue light. The studies showed significant improvements in the general picture of acne with blue light, considering the number and size of lesions, and as for inflammation, red light showed better results. It is concluded that despite the great potential in its use in the treatment of acne, there is a need for more detailed tests on the effect of blue light in this treatment.O tratamento da acne comumente é realizado com os retinóides, como o adapaleno, o ácido retinóico, a isotretinoína, que possuem características anti-comedogênicas, anti-inflamatórias e comedolíticas. A principal desvantagem da maioria dos retinóides tópicos está relacionada aos efeitos colaterais cutâneos. A acne geralmente melhora após a exposição à luz solar ou radiação ultra violeta produzida artificialmente. A presente pesquisa teve como objetivo analisar o uso da luz azul para tratamento da acne inflamatória. Foi realizada uma revisão sistemática de literatura, cujo protocolo de pesquisa seguiu a recomendação PRISMA, sendo incluídos na amostra estudos de ensaios clínicos, randomizados que compararam a luz azul com outra intervenção como controle. A pesquisa foi realizada nas bases de dados PUBMED e WEB of SCIENCE, combinando-se os termos "photobiomodulation", "Acne", "LLLT", Phototherapy, "LED" and “blue light”. A qualidade metodológica dos estudos incluídos foi avaliada por meio da Escala de Risco de Viés da Colaboração Cochrane. Após a exclusão das duplicatas, foram avaliados os títulos e resumos de 81 artigos, sendo selecionados 50 artigos para leitura na íntegra, incluindo-se na revisão ao final 8 artigos. Para tanto foram selecionados artigos entre os anos de 1990 até 2021. Foram analisados 8 ensaios clínicos controlados e randomizados usando a luz azul e um método comparativo. A maioria dos estudos comparou o uso da luz azul com o peróxido de benzoíla, e os outros utilizaram como comparativo outra fonte de luz ou placebo. Os estudos incluídos diferiram entre si quanto ao protocolo aplicado com a luz azul. Os estudos mostraram melhoras significativas no quadro geral da acne com a luz azul, considerando número e tamanho das lesões, e quanto à inflamação a luz vermelha demonstrou melhor resultado. Conclui-se que apesar do grande potencial em sua utilização no tratamento da acne, há necessidade de ensaios mais detalhados sobre o efeito da luz azul nesse tratamento.Submitted by Nadir Basilio (nadirsb@uninove.br) on 2021-10-26T20:22:39Z No. of bitstreams: 1 Mara Lúcia Gonçalves Diogo.pdf: 573458 bytes, checksum: c997a4c074248eefc36d892d9adf9e6d (MD5)Made available in DSpace on 2021-10-26T20:22:39Z (GMT). No. of bitstreams: 1 Mara Lúcia Gonçalves Diogo.pdf: 573458 bytes, checksum: c997a4c074248eefc36d892d9adf9e6d (MD5) Previous issue date: 2021-06-17application/pdfporUniversidade Nove de JulhoPrograma de Pós-Graduação em Biofotônica Aplicada às Ciências da SaúdeUNINOVEBrasilSaúdeacneLLLTLEDphotobiomodulationphototherapyblue lightCIENCIAS DA SAUDETratamento da acne vulgar com luz azul: uma revisão sistemáticaTreatment of acne vulgar with blue light: a systematic reviewinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALMara Lúcia Gonçalves Diogo.pdfMara Lúcia Gonçalves Diogo.pdfapplication/pdf573458http://localhost:8080/tede/bitstream/tede/2623/2/Mara+L%C3%BAcia+Gon%C3%A7alves+Diogo.pdfc997a4c074248eefc36d892d9adf9e6dMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/2623/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/26232021-10-26 18:22:39.837oai:localhost:tede/2623Tk9UQTogQ09MT1FVRSBBUVVJIEEgU1VBIFBSw5NQUklBIExJQ0VOw4dBCkVzdGEgbGljZW7Dp2EgZGUgZXhlbXBsbyDDqSBmb3JuZWNpZGEgYXBlbmFzIHBhcmEgZmlucyBpbmZvcm1hdGl2b3MuCgpMSUNFTsOHQSBERSBESVNUUklCVUnDh8ODTyBOw4NPLUVYQ0xVU0lWQQoKQ29tIGEgYXByZXNlbnRhw6fDo28gZGVzdGEgbGljZW7Dp2EsIHZvY8OqIChvIGF1dG9yIChlcykgb3UgbyB0aXR1bGFyIGRvcyBkaXJlaXRvcyBkZSBhdXRvcikgY29uY2VkZSDDoCBVbml2ZXJzaWRhZGUgClhYWCAoU2lnbGEgZGEgVW5pdmVyc2lkYWRlKSBvIGRpcmVpdG8gbsOjby1leGNsdXNpdm8gZGUgcmVwcm9kdXppciwgIHRyYWR1emlyIChjb25mb3JtZSBkZWZpbmlkbyBhYmFpeG8pLCBlL291IApkaXN0cmlidWlyIGEgc3VhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbyAoaW5jbHVpbmRvIG8gcmVzdW1vKSBwb3IgdG9kbyBvIG11bmRvIG5vIGZvcm1hdG8gaW1wcmVzc28gZSBlbGV0csO0bmljbyBlIAplbSBxdWFscXVlciBtZWlvLCBpbmNsdWluZG8gb3MgZm9ybWF0b3Mgw6F1ZGlvIG91IHbDrWRlby4KClZvY8OqIGNvbmNvcmRhIHF1ZSBhIFNpZ2xhIGRlIFVuaXZlcnNpZGFkZSBwb2RlLCBzZW0gYWx0ZXJhciBvIGNvbnRlw7pkbywgdHJhbnNwb3IgYSBzdWEgdGVzZSBvdSBkaXNzZXJ0YcOnw6NvIApwYXJhIHF1YWxxdWVyIG1laW8gb3UgZm9ybWF0byBwYXJhIGZpbnMgZGUgcHJlc2VydmHDp8Ojby4KClZvY8OqIHRhbWLDqW0gY29uY29yZGEgcXVlIGEgU2lnbGEgZGUgVW5pdmVyc2lkYWRlIHBvZGUgbWFudGVyIG1haXMgZGUgdW1hIGPDs3BpYSBhIHN1YSB0ZXNlIG91IApkaXNzZXJ0YcOnw6NvIHBhcmEgZmlucyBkZSBzZWd1cmFuw6dhLCBiYWNrLXVwIGUgcHJlc2VydmHDp8Ojby4KClZvY8OqIGRlY2xhcmEgcXVlIGEgc3VhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbyDDqSBvcmlnaW5hbCBlIHF1ZSB2b2PDqiB0ZW0gbyBwb2RlciBkZSBjb25jZWRlciBvcyBkaXJlaXRvcyBjb250aWRvcyAKbmVzdGEgbGljZW7Dp2EuIFZvY8OqIHRhbWLDqW0gZGVjbGFyYSBxdWUgbyBkZXDDs3NpdG8gZGEgc3VhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbyBuw6NvLCBxdWUgc2VqYSBkZSBzZXUgCmNvbmhlY2ltZW50bywgaW5mcmluZ2UgZGlyZWl0b3MgYXV0b3JhaXMgZGUgbmluZ3XDqW0uCgpDYXNvIGEgc3VhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbyBjb250ZW5oYSBtYXRlcmlhbCBxdWUgdm9jw6ogbsOjbyBwb3NzdWkgYSB0aXR1bGFyaWRhZGUgZG9zIGRpcmVpdG9zIGF1dG9yYWlzLCB2b2PDqiAKZGVjbGFyYSBxdWUgb2J0ZXZlIGEgcGVybWlzc8OjbyBpcnJlc3RyaXRhIGRvIGRldGVudG9yIGRvcyBkaXJlaXRvcyBhdXRvcmFpcyBwYXJhIGNvbmNlZGVyIMOgIFNpZ2xhIGRlIFVuaXZlcnNpZGFkZSAKb3MgZGlyZWl0b3MgYXByZXNlbnRhZG9zIG5lc3RhIGxpY2Vuw6dhLCBlIHF1ZSBlc3NlIG1hdGVyaWFsIGRlIHByb3ByaWVkYWRlIGRlIHRlcmNlaXJvcyBlc3TDoSBjbGFyYW1lbnRlIAppZGVudGlmaWNhZG8gZSByZWNvbmhlY2lkbyBubyB0ZXh0byBvdSBubyBjb250ZcO6ZG8gZGEgdGVzZSBvdSBkaXNzZXJ0YcOnw6NvIG9yYSBkZXBvc2l0YWRhLgoKQ0FTTyBBIFRFU0UgT1UgRElTU0VSVEHDh8ODTyBPUkEgREVQT1NJVEFEQSBURU5IQSBTSURPIFJFU1VMVEFETyBERSBVTSBQQVRST0PDjU5JTyBPVSAKQVBPSU8gREUgVU1BIEFHw4pOQ0lBIERFIEZPTUVOVE8gT1UgT1VUUk8gT1JHQU5JU01PIFFVRSBOw4NPIFNFSkEgQSBTSUdMQSBERSAKVU5JVkVSU0lEQURFLCBWT0PDiiBERUNMQVJBIFFVRSBSRVNQRUlUT1UgVE9ET1MgRSBRVUFJU1FVRVIgRElSRUlUT1MgREUgUkVWSVPDg08gQ09NTyAKVEFNQsOJTSBBUyBERU1BSVMgT0JSSUdBw4fDlUVTIEVYSUdJREFTIFBPUiBDT05UUkFUTyBPVSBBQ09SRE8uCgpBIFNpZ2xhIGRlIFVuaXZlcnNpZGFkZSBzZSBjb21wcm9tZXRlIGEgaWRlbnRpZmljYXIgY2xhcmFtZW50ZSBvIHNldSBub21lIChzKSBvdSBvKHMpIG5vbWUocykgZG8ocykgCmRldGVudG9yKGVzKSBkb3MgZGlyZWl0b3MgYXV0b3JhaXMgZGEgdGVzZSBvdSBkaXNzZXJ0YcOnw6NvLCBlIG7Do28gZmFyw6EgcXVhbHF1ZXIgYWx0ZXJhw6fDo28sIGFsw6ltIGRhcXVlbGFzIApjb25jZWRpZGFzIHBvciBlc3RhIGxpY2Vuw6dhLgo=Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2021-10-26T20:22:39Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false |
dc.title.por.fl_str_mv |
Tratamento da acne vulgar com luz azul: uma revisão sistemática |
dc.title.alternative.eng.fl_str_mv |
Treatment of acne vulgar with blue light: a systematic review |
title |
Tratamento da acne vulgar com luz azul: uma revisão sistemática |
spellingShingle |
Tratamento da acne vulgar com luz azul: uma revisão sistemática Diogo, Mara Lúcia Gonçalves acne LLLT LED photobiomodulation phototherapy blue light CIENCIAS DA SAUDE |
title_short |
Tratamento da acne vulgar com luz azul: uma revisão sistemática |
title_full |
Tratamento da acne vulgar com luz azul: uma revisão sistemática |
title_fullStr |
Tratamento da acne vulgar com luz azul: uma revisão sistemática |
title_full_unstemmed |
Tratamento da acne vulgar com luz azul: uma revisão sistemática |
title_sort |
Tratamento da acne vulgar com luz azul: uma revisão sistemática |
author |
Diogo, Mara Lúcia Gonçalves |
author_facet |
Diogo, Mara Lúcia Gonçalves |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Motta, Lara Jansiski |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/6750462252900819 |
dc.contributor.referee1.fl_str_mv |
Motta, Lara Jansiski |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/6750462252900819 |
dc.contributor.referee2.fl_str_mv |
Pavani, Christiane |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/2148910222765744 |
dc.contributor.referee3.fl_str_mv |
Fonseca, Elsa Susana Reis |
dc.contributor.author.fl_str_mv |
Diogo, Mara Lúcia Gonçalves |
contributor_str_mv |
Motta, Lara Jansiski Motta, Lara Jansiski Pavani, Christiane Fonseca, Elsa Susana Reis |
dc.subject.por.fl_str_mv |
acne LLLT LED |
topic |
acne LLLT LED photobiomodulation phototherapy blue light CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
photobiomodulation phototherapy blue light |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
Acne treatment is commonly performed with retinoids, such as adapalene, retinoic acid, isotretinoin, which have anti-comedogenic, anti-inflammatory , and comedolytic characteristics. The main disadvantage of most topical retinoids is related to cutaneous side effects. Acne usually improves after exposure to sunlight or artificially produced UV radiation. This research aimed to analyze the use of blue light for the treatment of inflammatory acne. A systematic literature review was carried out, whose research protocol followed the PRISMA recommendation, and randomized clinical trial studies that compared blue light with another intervention as a control were included in the sample. The search was carried out in the PUBMED and WEB of SCIENCE databases, combining the terms "photobiomodulation", "Acne", "LLLT", Phototherapy, "LED" and "blue light". The methodological quality of the included studies was assessed using the Cochrane Collaboration Risk of Bias Scale. After excluding duplicates, the titles, and abstracts of 81 articles were evaluated, and 50 articles were selected for full reading, including 8 articles in the review at the end. For this purpose, articles were selected from 1990 to 2021. Eight randomized controlled clinical trials were analyzed using blue light and a comparative method. Most studies compared the use of blue light with benzoyl peroxide, and the others used another light source or placebo as a comparison. The included studies differed from each other regarding the protocol applied with blue light. The studies showed significant improvements in the general picture of acne with blue light, considering the number and size of lesions, and as for inflammation, red light showed better results. It is concluded that despite the great potential in its use in the treatment of acne, there is a need for more detailed tests on the effect of blue light in this treatment. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-10-26T20:22:39Z |
dc.date.issued.fl_str_mv |
2021-06-17 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/masterThesis |
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masterThesis |
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dc.identifier.citation.fl_str_mv |
Diogo, Mara Lúcia Gonçalves. Tratamento da acne vulgar com luz azul: uma revisão sistemática. 2021. 43 f. Dissertação( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo. |
dc.identifier.uri.fl_str_mv |
http://bibliotecatede.uninove.br/handle/tede/2623 |
identifier_str_mv |
Diogo, Mara Lúcia Gonçalves. Tratamento da acne vulgar com luz azul: uma revisão sistemática. 2021. 43 f. Dissertação( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo. |
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http://bibliotecatede.uninove.br/handle/tede/2623 |
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por |
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openAccess |
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Universidade Nove de Julho |
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Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde |
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UNINOVE |
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Brasil |
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Saúde |
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Universidade Nove de Julho |
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