Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da Uninove |
Texto Completo: | http://bibliotecatede.uninove.br/handle/tede/2734 |
Resumo: | Patients with peripheral arterial disease (PAD) have decreased calf muscle area, damage to muscle fibers, impaired mitochondrial function and apoptosis due to the chronic ischemia process, causing losses in physical activity and cardiovascular health. However, there is no evidence on the potential role of calf circumference (CC) measurement and its relationship with cardiovascular health indicators in these patients. The aim of the present study was to evaluate the relationship between CC and cardiovascular function indicators in patients with PAD. Patients with PAD in São Paulo were recruited from 2015 to 2019. Anthropometric data including CC and cardiovascular indicators were obtained: blood pressure, arterial stiffness indicators and heart rate variability (HRV) indicators. For data analysis, binary logistics were used, with the first quartile of CC as risk. The multivariate analysis used age and ankle brachial index (ABI) as adjustments. CC was associated with ABI in both sexes (men: OR=4.998, p=0.005; women: OR=2.289, p=0.029). In women, there was an association between CC and the increase index corrected by 75 bpm (OR=4.438, p=0.015). In men, there was an association between CC and rMSSD (OR=3.010, p=0.011), pNN50 (OR=2.695, p=0.018), low frequency bands (OR=6.315, p<0.001) and high frequency bands (OR=6.314, p<0.001). In conclusion, in patients with PAD, CC was associated with cardiovascular indicators and ABI. In women, this association was established with indicators of arterial stiffness, in men with indicators of HRV. |
id |
NOVE_611857fe893f59b78bd64692130f5d8d |
---|---|
oai_identifier_str |
oai:localhost:tede/2734 |
network_acronym_str |
NOVE |
network_name_str |
Biblioteca Digital de Teses e Dissertações da Uninove |
repository_id_str |
|
spelling |
Correia, Marilia de Almeidahttp://lattes.cnpq.br/5983044080494563Correia, Marilia de Almeidahttp://lattes.cnpq.br/5983044080494563Elias, Rosilene Mottahttp://lattes.cnpq.br/9742090948110017Kanegusuku, Hélciohttp://lattes.cnpq.br/3841903268862826http://lattes.cnpq.br/0792040227014811Ferreira, Fabiana Gonçalves2021-11-12T15:42:21Z2021-06-28Ferreira, Fabiana Gonçalves. Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica. 2021. 84 f. Dissertação( Programa de Mestrado em Medicina) - Universidade Nove de Julho, São Paulo.http://bibliotecatede.uninove.br/handle/tede/2734Patients with peripheral arterial disease (PAD) have decreased calf muscle area, damage to muscle fibers, impaired mitochondrial function and apoptosis due to the chronic ischemia process, causing losses in physical activity and cardiovascular health. However, there is no evidence on the potential role of calf circumference (CC) measurement and its relationship with cardiovascular health indicators in these patients. The aim of the present study was to evaluate the relationship between CC and cardiovascular function indicators in patients with PAD. Patients with PAD in São Paulo were recruited from 2015 to 2019. Anthropometric data including CC and cardiovascular indicators were obtained: blood pressure, arterial stiffness indicators and heart rate variability (HRV) indicators. For data analysis, binary logistics were used, with the first quartile of CC as risk. The multivariate analysis used age and ankle brachial index (ABI) as adjustments. CC was associated with ABI in both sexes (men: OR=4.998, p=0.005; women: OR=2.289, p=0.029). In women, there was an association between CC and the increase index corrected by 75 bpm (OR=4.438, p=0.015). In men, there was an association between CC and rMSSD (OR=3.010, p=0.011), pNN50 (OR=2.695, p=0.018), low frequency bands (OR=6.315, p<0.001) and high frequency bands (OR=6.314, p<0.001). In conclusion, in patients with PAD, CC was associated with cardiovascular indicators and ABI. In women, this association was established with indicators of arterial stiffness, in men with indicators of HRV.Pacientes com a doença arterial periférica (DAP) apresentam diminuição da área muscular da panturrilha, danos nas fibras musculares, prejuízo na função mitocondrial e apoptose devido ao processo de isquemia crônica, gerando prejuízos na realização de atividade física e saúde cardiovascular. No entanto, não há evidências sobre o potencial papel da medida da circunferência da panturrilha (CP) e sua relação com indicadores de saúde cardiovascular nesses pacientes. O objetivo do presente estudo foi avaliar a relação da CP com indicadores da função cardiovascular em pacientes com DAP. Foram recrutados pacientes com DAP em São Paulo no período de 2015 a 2019. Foram obtidos os dados antropométricos incluindo a CP e indicadores cardiovasculares: pressão arterial, indicadores de rigidez arterial e indicadores da variabilidade da frequência cardíaca (VFC). Para análise de dados utilizou-se a logística binária tendo como risco o primeiro quartil da CP. A análise multivariada utilizou como ajustes a idade e o índice tornozelo braço (ITB). A CP se associou com o ITB em ambos os sexos (homens: OR=4,998, p=0,005; mulheres: OR= 2,289, p=0,029). Nas mulheres, houve associação entre a CP e o índice de aumento corrigido por 75 bpm (OR=4,438, p=0,015). Nos homens, houve associação entre a CP e rMSSD (OR=3,010, p=0,011), pNN50 (OR=2,695, p=0,018), bandas de baixa frequência (OR=6,315, p<0,001) e bandas e alta frequência (OR=6,314, p<0,001). Em conclusão, em pacientes com DAP, a CP se associou com indicadores cardiovasculares e ITB. Em mulheres essa associação se estabeleceu com indicadores da rigidez arterial, em homens com indicadores da VFC.Submitted by Nadir Basilio (nadirsb@uninove.br) on 2021-11-12T15:42:21Z No. of bitstreams: 1 Fabiana Gonçalves.pdf: 1743542 bytes, checksum: d022df6e0bcc1e229f801f384ce2b479 (MD5)Made available in DSpace on 2021-11-12T15:42:21Z (GMT). No. of bitstreams: 1 Fabiana Gonçalves.pdf: 1743542 bytes, checksum: d022df6e0bcc1e229f801f384ce2b479 (MD5) Previous issue date: 2021-06-28application/pdfporUniversidade Nove de JulhoPrograma de Mestrado em MedicinaUNINOVEBrasilSaúdedoença arterial periféricacircunferência da panturrilhasistema cardiovascularperipheral arterial diseasecalf circumferencecardiovascular systemCIENCIAS DA SAUDERelação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periféricaRelationship between calf circumference and indicators of cardiovascular function in patients with peripheral arterial diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALFabiana Gonçalves.pdfFabiana Gonçalves.pdfapplication/pdf1743542http://localhost:8080/tede/bitstream/tede/2734/2/Fabiana+Gon%C3%A7alves.pdfd022df6e0bcc1e229f801f384ce2b479MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/2734/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/27342021-11-12 13:42:21.513oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2021-11-12T15:42:21Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false |
dc.title.por.fl_str_mv |
Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica |
dc.title.alternative.eng.fl_str_mv |
Relationship between calf circumference and indicators of cardiovascular function in patients with peripheral arterial disease |
title |
Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica |
spellingShingle |
Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica Ferreira, Fabiana Gonçalves doença arterial periférica circunferência da panturrilha sistema cardiovascular peripheral arterial disease calf circumference cardiovascular system CIENCIAS DA SAUDE |
title_short |
Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica |
title_full |
Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica |
title_fullStr |
Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica |
title_full_unstemmed |
Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica |
title_sort |
Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica |
author |
Ferreira, Fabiana Gonçalves |
author_facet |
Ferreira, Fabiana Gonçalves |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Correia, Marilia de Almeida |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/5983044080494563 |
dc.contributor.referee1.fl_str_mv |
Correia, Marilia de Almeida |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/5983044080494563 |
dc.contributor.referee2.fl_str_mv |
Elias, Rosilene Motta |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/9742090948110017 |
dc.contributor.referee3.fl_str_mv |
Kanegusuku, Hélcio |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/3841903268862826 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/0792040227014811 |
dc.contributor.author.fl_str_mv |
Ferreira, Fabiana Gonçalves |
contributor_str_mv |
Correia, Marilia de Almeida Correia, Marilia de Almeida Elias, Rosilene Motta Kanegusuku, Hélcio |
dc.subject.por.fl_str_mv |
doença arterial periférica circunferência da panturrilha sistema cardiovascular |
topic |
doença arterial periférica circunferência da panturrilha sistema cardiovascular peripheral arterial disease calf circumference cardiovascular system CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
peripheral arterial disease calf circumference cardiovascular system |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
Patients with peripheral arterial disease (PAD) have decreased calf muscle area, damage to muscle fibers, impaired mitochondrial function and apoptosis due to the chronic ischemia process, causing losses in physical activity and cardiovascular health. However, there is no evidence on the potential role of calf circumference (CC) measurement and its relationship with cardiovascular health indicators in these patients. The aim of the present study was to evaluate the relationship between CC and cardiovascular function indicators in patients with PAD. Patients with PAD in São Paulo were recruited from 2015 to 2019. Anthropometric data including CC and cardiovascular indicators were obtained: blood pressure, arterial stiffness indicators and heart rate variability (HRV) indicators. For data analysis, binary logistics were used, with the first quartile of CC as risk. The multivariate analysis used age and ankle brachial index (ABI) as adjustments. CC was associated with ABI in both sexes (men: OR=4.998, p=0.005; women: OR=2.289, p=0.029). In women, there was an association between CC and the increase index corrected by 75 bpm (OR=4.438, p=0.015). In men, there was an association between CC and rMSSD (OR=3.010, p=0.011), pNN50 (OR=2.695, p=0.018), low frequency bands (OR=6.315, p<0.001) and high frequency bands (OR=6.314, p<0.001). In conclusion, in patients with PAD, CC was associated with cardiovascular indicators and ABI. In women, this association was established with indicators of arterial stiffness, in men with indicators of HRV. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-11-12T15:42:21Z |
dc.date.issued.fl_str_mv |
2021-06-28 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Ferreira, Fabiana Gonçalves. Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica. 2021. 84 f. Dissertação( Programa de Mestrado em Medicina) - Universidade Nove de Julho, São Paulo. |
dc.identifier.uri.fl_str_mv |
http://bibliotecatede.uninove.br/handle/tede/2734 |
identifier_str_mv |
Ferreira, Fabiana Gonçalves. Relação entre circunferência da panturrilha e indicadores da função cardiovascular de pacientes com doença arterial periférica. 2021. 84 f. Dissertação( Programa de Mestrado em Medicina) - Universidade Nove de Julho, São Paulo. |
url |
http://bibliotecatede.uninove.br/handle/tede/2734 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.cnpq.fl_str_mv |
8765449414823306929 |
dc.relation.confidence.fl_str_mv |
600 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Nove de Julho |
dc.publisher.program.fl_str_mv |
Programa de Mestrado em Medicina |
dc.publisher.initials.fl_str_mv |
UNINOVE |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Saúde |
publisher.none.fl_str_mv |
Universidade Nove de Julho |
dc.source.none.fl_str_mv |
reponame:Biblioteca Digital de Teses e Dissertações da Uninove instname:Universidade Nove de Julho (UNINOVE) instacron:UNINOVE |
instname_str |
Universidade Nove de Julho (UNINOVE) |
instacron_str |
UNINOVE |
institution |
UNINOVE |
reponame_str |
Biblioteca Digital de Teses e Dissertações da Uninove |
collection |
Biblioteca Digital de Teses e Dissertações da Uninove |
bitstream.url.fl_str_mv |
http://localhost:8080/tede/bitstream/tede/2734/2/Fabiana+Gon%C3%A7alves.pdf http://localhost:8080/tede/bitstream/tede/2734/1/license.txt |
bitstream.checksum.fl_str_mv |
d022df6e0bcc1e229f801f384ce2b479 bd3efa91386c1718a7f26a329fdcb468 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
repository.name.fl_str_mv |
Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE) |
repository.mail.fl_str_mv |
bibliotecatede@uninove.br||bibliotecatede@uninove.br |
_version_ |
1811016885130493952 |