Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da Uninove |
Texto Completo: | http://bibliotecatede.uninove.br/tede/handle/tede/911 |
Resumo: | Background: Asthma is the most common chronic respiratory disease in childhood. The most striking feature is the persistent inflammation of the airways, even in periods of crisis. The imbalance between the pro and anti-inflammatory mechanisms are responsible for this chronic inflammation as an autonomic dysfunction that exerts an important influence on pathogenesis and control of the disease. The impact of these changes takes these children a patho-physiological cycle of underactive and sedentariness influencing on functional capacity and making the control of the disease worse. Objectives: to evaluate the autonomic modulation of asthmatic children in crisis and in stable phase, the effect of continuous positive airway pressure (CPAP) on airway permeability and autonomic modulation, evaluate the response of the autonomic nervous system (ANS) is at maximum and submaximal exercise and assess the effectiveness of a rehabilitation programme with active video game. Methods: 3 cross-sectional studies and a clinical trial were carried out, in which were evaluated 40 asthmatic children who underwent pulmonary function test (PFT), exhaled Nitric Oxide (FeNO), exercise testing (ET), respiratory muscle strength assessment (RMS), heart rate variability (HRV), Incremental Shuttle Walk Test (ISWT), 3-minute step test (ST3), Asthma control questionnaire (ACQ6), anthropometric measurements and tetrapolar bioelectrical impedance. Results: it was found a prevalence of sympathetic nervous system on asthma crisis unlike the stable phase, in which there is predominance of the parasympathetic nervous system. During the maximum test of asthmatic children hasn t had vagal withdrawal. The peak flow has increased after the withdrawal of CPAP, translating as possible, in addition to the mechanical effect bronchodilation positive pressure. Training with active video game caused a maximum expenditure of energy, bigger than on the treadmill, and featured improved functional capacity and lung inflammation. Conclusion: there is a difference in the autonomic modulation of asthmatic children in stable phase and during the crisis, as well as ANS's response to maximum physical effort when compared to the submaximal exercise. The CPAP promoted a possible bronchodilation, besides the mechanical effect; Is possible perform aerobic training with active video game, with positive outcome in lung inflammation. |
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Costa, Dirceuhttp://lattes.cnpq.br/7541914413496897Sampaio, Luciana Maria Malos??http://lattes.cnpq.br/2970138065407046Corso, Simone DalCPF:00000000000http://lattes.cnpq.br/9690847988531306Angelis, Katia dehttp://lattes.cnpq.br/4299344810509965Carvalho, Celso Ricardo Fernandeshttp://lattes.cnpq.br/6979390792377484Stirbulov, Robertohttp://lattes.cnpq.br/7405136359510218CPF:25797634813Gomes, ??velim Leal de Freitas Dantas2015-04-22T17:20:47Z2014-12-032013-11-27GOMES, ??velim Leal de Freitas Dantas. Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios. 2013. 75 f. Tese (Doutorado em Sa??de) - Universidade Nove de Julho, S??o Paulo, 2013.http://bibliotecatede.uninove.br/tede/handle/tede/911Background: Asthma is the most common chronic respiratory disease in childhood. The most striking feature is the persistent inflammation of the airways, even in periods of crisis. The imbalance between the pro and anti-inflammatory mechanisms are responsible for this chronic inflammation as an autonomic dysfunction that exerts an important influence on pathogenesis and control of the disease. The impact of these changes takes these children a patho-physiological cycle of underactive and sedentariness influencing on functional capacity and making the control of the disease worse. Objectives: to evaluate the autonomic modulation of asthmatic children in crisis and in stable phase, the effect of continuous positive airway pressure (CPAP) on airway permeability and autonomic modulation, evaluate the response of the autonomic nervous system (ANS) is at maximum and submaximal exercise and assess the effectiveness of a rehabilitation programme with active video game. Methods: 3 cross-sectional studies and a clinical trial were carried out, in which were evaluated 40 asthmatic children who underwent pulmonary function test (PFT), exhaled Nitric Oxide (FeNO), exercise testing (ET), respiratory muscle strength assessment (RMS), heart rate variability (HRV), Incremental Shuttle Walk Test (ISWT), 3-minute step test (ST3), Asthma control questionnaire (ACQ6), anthropometric measurements and tetrapolar bioelectrical impedance. Results: it was found a prevalence of sympathetic nervous system on asthma crisis unlike the stable phase, in which there is predominance of the parasympathetic nervous system. During the maximum test of asthmatic children hasn t had vagal withdrawal. The peak flow has increased after the withdrawal of CPAP, translating as possible, in addition to the mechanical effect bronchodilation positive pressure. Training with active video game caused a maximum expenditure of energy, bigger than on the treadmill, and featured improved functional capacity and lung inflammation. Conclusion: there is a difference in the autonomic modulation of asthmatic children in stable phase and during the crisis, as well as ANS's response to maximum physical effort when compared to the submaximal exercise. The CPAP promoted a possible bronchodilation, besides the mechanical effect; Is possible perform aerobic training with active video game, with positive outcome in lung inflammation.Contextualiza????o: A asma ?? uma doen??a respirat??ria cr??nica comum na inf??ncia. A caracter??stica mais marcante ?? a inflama????o persistente das vias a??reas, mesmo nos per??odos fora da crise. O desequil??brio entre os mecanismos pr?? e antiinflamat??rio ?? respons??vel por esta inflama????o cr??nica al??m de uma disfun????o auton??mica que exerce uma influ??ncia importante na patog??nese e no controle da doen??a. O impacto destas altera????es fisiopatol??gicas leva estas crian??as a um ciclo de hipoatividade e sedentarismo influenciando na capacidade funcional e dificultando o controle da doen??a. Objetivos: Avaliar a modula????o auton??mica de crian??as asm??ticas na crise e na fase est??vel, o efeito da press??o positiva cont??nua nas vias a??reas (CPAP) na permeabilidade da via a??rea e na modula????o auton??mica, avaliar a resposta do sistema nervoso auton??mico (SNA) em n??vel m??ximo e subm??ximo de esfor??o f??sico e avaliar a efic??cia de um programa de reabilita????o com v??deo game ativo. M??todos: Foram realizados 3 estudos transversais e um ensaio cl??nico, nos quais foram avaliadas 40 crian??as asm??ticas que se submeteram aprova de fun????o pulmonar (PFP), ??xido N??trico exalado (FeNO), teste ergom??trico (TE), avalia????o de for??a muscular respirat??ria (FMR),variabilidade da freq????ncia card??aca (VFC), Incremental Shuttle Walk Test(ISWT), Teste de Degrau de 3 minutos (TD3), Asthma control questionnaire (ACQ6), medidas antropom??tricas e bioimped??ncia tetrapolar. Resultados: Foi encontrada uma predomin??ncia do sistema nervoso simp??tico na crise de asma ao contr??rio da fase est??vel, em que h?? predomin??ncia do sistema nervoso parassimp??tico. Durante o teste m??ximo, as crian??as asm??ticas n??o fizeram retirada vagal. O peak flow aumentou ap??s a retirada da CPAP, traduzindo poss??vel broncodilata????o, al??m do efeito mec??nico da press??o positiva. O treinamento com v??deo game ativo causou um disp??ndio m??ximo de energia, maior que na esteira, e apresentou melhora da capacidade funcional e inflama????o pulmonar. Conclus??o: H?? diferen??a na modula????o auton??mica das crian??as asm??ticas, na fase est??vel e durante a crise, assim como a resposta do SNA ao esfor??o f??sico m??ximo, quando comparado ao subm??ximo. A CPAP promoveu uma poss??vel broncodilata????o, al??m do efeito mec??nico; ?? poss??vel realizar treinamento aer??bio com v??deo game ativo, com resultado positivo na inflama????o pulmonar.Made available in DSpace on 2015-04-22T17:20:47Z (GMT). No. of bitstreams: 1 Evelim Leal de Freitas Dantas.pdf: 1241922 bytes, checksum: dd1b6c4efcefcbe68b0eddd3ad1bc324 (MD5) Previous issue date: 2013-11-27application/pdfporUniversidade Nove de JulhoPrograma de P??s-Gradua????o em Ci??ncias da Reabilita????oUNINOVEBRSa??deasmamodalidade de fisioterapiaexerc??cio f??sicoinflama????osistema nervoso aut??nomoCPAPasthmaphysiotherapyexerciseinflammationautonomic nervous systemCPAPCIENCIAS DA SAUDEAvalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??riosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALEvelim Leal de Freitas Dantas.pdfapplication/pdf1241922http://localhost:8080/tede/bitstream/tede/911/1/Evelim+Leal+de+Freitas+Dantas.pdfdd1b6c4efcefcbe68b0eddd3ad1bc324MD51tede/9112018-06-15 12:24:36.063oai:localhost:tede/911Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2018-06-15T15:24:36Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false |
dc.title.por.fl_str_mv |
Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios |
title |
Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios |
spellingShingle |
Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios Gomes, ??velim Leal de Freitas Dantas asma modalidade de fisioterapia exerc??cio f??sico inflama????o sistema nervoso aut??nomo CPAP asthma physiotherapy exercise inflammation autonomic nervous system CPAP CIENCIAS DA SAUDE |
title_short |
Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios |
title_full |
Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios |
title_fullStr |
Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios |
title_full_unstemmed |
Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios |
title_sort |
Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios |
author |
Gomes, ??velim Leal de Freitas Dantas |
author_facet |
Gomes, ??velim Leal de Freitas Dantas |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Costa, Dirceu |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/7541914413496897 |
dc.contributor.advisor-co1.fl_str_mv |
Sampaio, Luciana Maria Malos?? |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/2970138065407046 |
dc.contributor.referee1.fl_str_mv |
Corso, Simone Dal |
dc.contributor.referee1ID.fl_str_mv |
CPF:00000000000 |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/9690847988531306 |
dc.contributor.referee2.fl_str_mv |
Angelis, Katia de |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/4299344810509965 |
dc.contributor.referee3.fl_str_mv |
Carvalho, Celso Ricardo Fernandes |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/6979390792377484 |
dc.contributor.referee4.fl_str_mv |
Stirbulov, Roberto |
dc.contributor.referee4Lattes.fl_str_mv |
http://lattes.cnpq.br/7405136359510218 |
dc.contributor.authorID.fl_str_mv |
CPF:25797634813 |
dc.contributor.author.fl_str_mv |
Gomes, ??velim Leal de Freitas Dantas |
contributor_str_mv |
Costa, Dirceu Sampaio, Luciana Maria Malos?? Corso, Simone Dal Angelis, Katia de Carvalho, Celso Ricardo Fernandes Stirbulov, Roberto |
dc.subject.por.fl_str_mv |
asma modalidade de fisioterapia exerc??cio f??sico inflama????o sistema nervoso aut??nomo CPAP |
topic |
asma modalidade de fisioterapia exerc??cio f??sico inflama????o sistema nervoso aut??nomo CPAP asthma physiotherapy exercise inflammation autonomic nervous system CPAP CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
asthma physiotherapy exercise inflammation autonomic nervous system CPAP |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
Background: Asthma is the most common chronic respiratory disease in childhood. The most striking feature is the persistent inflammation of the airways, even in periods of crisis. The imbalance between the pro and anti-inflammatory mechanisms are responsible for this chronic inflammation as an autonomic dysfunction that exerts an important influence on pathogenesis and control of the disease. The impact of these changes takes these children a patho-physiological cycle of underactive and sedentariness influencing on functional capacity and making the control of the disease worse. Objectives: to evaluate the autonomic modulation of asthmatic children in crisis and in stable phase, the effect of continuous positive airway pressure (CPAP) on airway permeability and autonomic modulation, evaluate the response of the autonomic nervous system (ANS) is at maximum and submaximal exercise and assess the effectiveness of a rehabilitation programme with active video game. Methods: 3 cross-sectional studies and a clinical trial were carried out, in which were evaluated 40 asthmatic children who underwent pulmonary function test (PFT), exhaled Nitric Oxide (FeNO), exercise testing (ET), respiratory muscle strength assessment (RMS), heart rate variability (HRV), Incremental Shuttle Walk Test (ISWT), 3-minute step test (ST3), Asthma control questionnaire (ACQ6), anthropometric measurements and tetrapolar bioelectrical impedance. Results: it was found a prevalence of sympathetic nervous system on asthma crisis unlike the stable phase, in which there is predominance of the parasympathetic nervous system. During the maximum test of asthmatic children hasn t had vagal withdrawal. The peak flow has increased after the withdrawal of CPAP, translating as possible, in addition to the mechanical effect bronchodilation positive pressure. Training with active video game caused a maximum expenditure of energy, bigger than on the treadmill, and featured improved functional capacity and lung inflammation. Conclusion: there is a difference in the autonomic modulation of asthmatic children in stable phase and during the crisis, as well as ANS's response to maximum physical effort when compared to the submaximal exercise. The CPAP promoted a possible bronchodilation, besides the mechanical effect; Is possible perform aerobic training with active video game, with positive outcome in lung inflammation. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013-11-27 |
dc.date.available.fl_str_mv |
2014-12-03 |
dc.date.accessioned.fl_str_mv |
2015-04-22T17:20:47Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/doctoralThesis |
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doctoralThesis |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
GOMES, ??velim Leal de Freitas Dantas. Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios. 2013. 75 f. Tese (Doutorado em Sa??de) - Universidade Nove de Julho, S??o Paulo, 2013. |
dc.identifier.uri.fl_str_mv |
http://bibliotecatede.uninove.br/tede/handle/tede/911 |
identifier_str_mv |
GOMES, ??velim Leal de Freitas Dantas. Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios. 2013. 75 f. Tese (Doutorado em Sa??de) - Universidade Nove de Julho, S??o Paulo, 2013. |
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http://bibliotecatede.uninove.br/tede/handle/tede/911 |
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por |
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Universidade Nove de Julho |
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Programa de P??s-Gradua????o em Ci??ncias da Reabilita????o |
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UNINOVE |
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BR |
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Sa??de |
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Universidade Nove de Julho |
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