Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da Uninove |
Texto Completo: | http://bibliotecatede.uninove.br/handle/tede/2660 |
Resumo: | Halitosis, also known as bad breath, is a term used to define an unpleasant and foul odor that emanates from the mouth and may have local or systemic origin. This project aimed to verify if the treatment with antimicrobial photodynamic therapy (aPDT) with annatto and a light emitting diode (LED) is effective against it. A total of 44 students or UNINOVE employees with a diagnosis of halitosis were selected, presenting sulfite (SH2) ≥ 112 ppb in gas chromatography. The patients were randomly divided into 3 groups, which received different treatments: Group 1 (n=15): aPDT applied in the region of the back and middle thirds of the tongue; Group 2 (n=14): treatment with tongue scraper; Group 3 (n=15): combined treatment of tongue scraper and aPDT. For aPDT, annatto was used in a concentration of 20% (Fórmula e Ação®) applied in sufficient amount to cover the back and middle third of the tongue for 2 minutes for incubation, associated with a LED (Valo Cordless Ultradent®). Six points were irradiated on the back of the tongue with a distance of 1 cm between the points, considering the halo of light scattering and effectiveness of aPDT. The apparatus was previously calibrated at wavelength 395-480 nm for 20 seconds and energy of 9.6 J per point. The results of the halimetry were compared before, immediately after treatment and 7 days after. For the analysis of data from the Oral ChromaTM, the Friedman test was used for the intragroup analysis and the Kruskal Wallis test for the intergroup analysis. In all groups, there was a statistically significant difference between the initial sulfhydride value and the value immediately after the treatment (p <0.05). In Groups 1 and 3, there no was difference between the baseline value and the control of seven days. In Group 2, these times were not similar. There was no statistical difference between treatments. |
id |
NOVE_cdaa6dacfacc28b5ffd6ac68efa55d03 |
---|---|
oai_identifier_str |
oai:localhost:tede/2660 |
network_acronym_str |
NOVE |
network_name_str |
Biblioteca Digital de Teses e Dissertações da Uninove |
repository_id_str |
|
spelling |
Bussadori, Sandra Kalilhttp://lattes.cnpq.br/4110914499694913Bussadori, Sandra Kalilhttp://lattes.cnpq.br/4110914499694913Motta, Lara Jansiskihttp://lattes.cnpq.br/6750462252900819Horliana, Anna Carolina Ratto Tempestinihttp://lattes.cnpq.br/0442315483134442Machado, Maria Aparecida de Andrade Moreirahttp://lattes.cnpq.br/2141932552644466Santos, Elaine Marcíliohttp://lattes.cnpq.br/6292104584930744http://lattes.cnpq.br/3368360911943035Gonçalves, Marcela Leticia Leal2021-11-04T15:49:23Z2018-12-18Gonçalves, Marcela Leticia Leal. Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado. 2018. 60 f. Tese( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo.http://bibliotecatede.uninove.br/handle/tede/2660Halitosis, also known as bad breath, is a term used to define an unpleasant and foul odor that emanates from the mouth and may have local or systemic origin. This project aimed to verify if the treatment with antimicrobial photodynamic therapy (aPDT) with annatto and a light emitting diode (LED) is effective against it. A total of 44 students or UNINOVE employees with a diagnosis of halitosis were selected, presenting sulfite (SH2) ≥ 112 ppb in gas chromatography. The patients were randomly divided into 3 groups, which received different treatments: Group 1 (n=15): aPDT applied in the region of the back and middle thirds of the tongue; Group 2 (n=14): treatment with tongue scraper; Group 3 (n=15): combined treatment of tongue scraper and aPDT. For aPDT, annatto was used in a concentration of 20% (Fórmula e Ação®) applied in sufficient amount to cover the back and middle third of the tongue for 2 minutes for incubation, associated with a LED (Valo Cordless Ultradent®). Six points were irradiated on the back of the tongue with a distance of 1 cm between the points, considering the halo of light scattering and effectiveness of aPDT. The apparatus was previously calibrated at wavelength 395-480 nm for 20 seconds and energy of 9.6 J per point. The results of the halimetry were compared before, immediately after treatment and 7 days after. For the analysis of data from the Oral ChromaTM, the Friedman test was used for the intragroup analysis and the Kruskal Wallis test for the intergroup analysis. In all groups, there was a statistically significant difference between the initial sulfhydride value and the value immediately after the treatment (p <0.05). In Groups 1 and 3, there no was difference between the baseline value and the control of seven days. In Group 2, these times were not similar. There was no statistical difference between treatments.A halitose, também conhecida como mau hálito, é um termo utilizado para definir um odor desagradável e fétido que emana da boca, podendo apresentar origem local ou sistêmica. Este projeto teve como objetivo verificar se o tratamento com terapia fotodinâmica antimicrobiana (aPDT) com urucum e um diodo emissor de luz (LED) é eficaz contra esta. Foram selecionados 44 alunos ou funcionários da UNINOVE com diagnóstico de halitose, apresentando na cromatografia gasosa o sulfidreto (SH2) ≥ 112 ppb. Os pacientes foram divididos aleatoriamente em 3 grupos, que receberam tratamentos distintos: Grupo 1 (n=15): aPDT aplicada na região de dorso e terço médio da língua; Grupo 2 (n=14): tratamento com raspador de língua; Grupo 3 (n=15): tratamento combinado de raspador de língua e aPDT. Para a aPDT foi utilizado o urucum manipulado na concentração 20% (Fórmula e Ação®) em spray, aplicado em quantidade suficiente para cobrir o terço médio e dorso da língua por 2 minutos para incubação, associado a um LED azul (Valo Cordless Ultradent®). Foram irradiados 6 pontos no dorso da língua com distância de 1 cm entre os pontos, considerando o halo de espalhamento da luz e efetividade da aPDT. O aparelho foi previamente calibrado com comprimento de onda 395-480 nm, durante 20 segundos e energia de 9,6 J por ponto. Foram comparados os resultados da halimetria antes, imediatamente após o tratamento e 7 dias após. Para a análise dos dados oriundos do Oral ChromaTM, foi utilizado o teste de Friedman para a análise intragrupo e o teste de Kruskal Wallis para a análise entregrupos. Em todos os grupos, houve diferença estatisticamente significante entre o valor de sulfidreto inicial e o valor imediatamente após o tratamento (p<0,05). Nos Grupos 1 e 3, não houve diferença entre o valor inicial e o controle de sete dias. No Grupo 2, esses tempos não foram semelhantes. Não houve diferença estatística entre os tratamentos.Submitted by Nadir Basilio (nadirsb@uninove.br) on 2021-11-04T15:49:22Z No. of bitstreams: 1 Marcela Leticia Leal Gonçalves.pdf: 2216247 bytes, checksum: b921ea7511ecd8cf2972977e2d7867be (MD5)Made available in DSpace on 2021-11-04T15:49:23Z (GMT). No. of bitstreams: 1 Marcela Leticia Leal Gonçalves.pdf: 2216247 bytes, checksum: b921ea7511ecd8cf2972977e2d7867be (MD5) Previous issue date: 2018-12-18application/pdfporUniversidade Nove de JulhoPrograma de Pós-Graduação em Biofotônica Aplicada às Ciências da SaúdeUNINOVEBrasilSaúdehalitoseterapia fotodinâmicabixa orellanaensaio clínicoLEDhalitosisphotodynamic therapybixa orellanaclinical trialLEDCIENCIAS DA SAUDEEfeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizadoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALMarcela Leticia Leal Gonçalves.pdfMarcela Leticia Leal Gonçalves.pdfapplication/pdf2216247http://localhost:8080/tede/bitstream/tede/2660/2/Marcela+Leticia+Leal+Gon%C3%A7alves.pdfb921ea7511ecd8cf2972977e2d7867beMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/2660/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/26602021-11-04 13:49:23.937oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2021-11-04T15:49:23Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false |
dc.title.por.fl_str_mv |
Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado |
title |
Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado |
spellingShingle |
Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado Gonçalves, Marcela Leticia Leal halitose terapia fotodinâmica bixa orellana ensaio clínico LED halitosis photodynamic therapy bixa orellana clinical trial LED CIENCIAS DA SAUDE |
title_short |
Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado |
title_full |
Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado |
title_fullStr |
Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado |
title_full_unstemmed |
Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado |
title_sort |
Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado |
author |
Gonçalves, Marcela Leticia Leal |
author_facet |
Gonçalves, Marcela Leticia Leal |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Bussadori, Sandra Kalil |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/4110914499694913 |
dc.contributor.referee1.fl_str_mv |
Bussadori, Sandra Kalil |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/4110914499694913 |
dc.contributor.referee2.fl_str_mv |
Motta, Lara Jansiski |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/6750462252900819 |
dc.contributor.referee3.fl_str_mv |
Horliana, Anna Carolina Ratto Tempestini |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/0442315483134442 |
dc.contributor.referee4.fl_str_mv |
Machado, Maria Aparecida de Andrade Moreira |
dc.contributor.referee4Lattes.fl_str_mv |
http://lattes.cnpq.br/2141932552644466 |
dc.contributor.referee5.fl_str_mv |
Santos, Elaine Marcílio |
dc.contributor.referee5Lattes.fl_str_mv |
http://lattes.cnpq.br/6292104584930744 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/3368360911943035 |
dc.contributor.author.fl_str_mv |
Gonçalves, Marcela Leticia Leal |
contributor_str_mv |
Bussadori, Sandra Kalil Bussadori, Sandra Kalil Motta, Lara Jansiski Horliana, Anna Carolina Ratto Tempestini Machado, Maria Aparecida de Andrade Moreira Santos, Elaine Marcílio |
dc.subject.por.fl_str_mv |
halitose terapia fotodinâmica bixa orellana ensaio clínico LED |
topic |
halitose terapia fotodinâmica bixa orellana ensaio clínico LED halitosis photodynamic therapy bixa orellana clinical trial LED CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
halitosis photodynamic therapy bixa orellana clinical trial LED |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
Halitosis, also known as bad breath, is a term used to define an unpleasant and foul odor that emanates from the mouth and may have local or systemic origin. This project aimed to verify if the treatment with antimicrobial photodynamic therapy (aPDT) with annatto and a light emitting diode (LED) is effective against it. A total of 44 students or UNINOVE employees with a diagnosis of halitosis were selected, presenting sulfite (SH2) ≥ 112 ppb in gas chromatography. The patients were randomly divided into 3 groups, which received different treatments: Group 1 (n=15): aPDT applied in the region of the back and middle thirds of the tongue; Group 2 (n=14): treatment with tongue scraper; Group 3 (n=15): combined treatment of tongue scraper and aPDT. For aPDT, annatto was used in a concentration of 20% (Fórmula e Ação®) applied in sufficient amount to cover the back and middle third of the tongue for 2 minutes for incubation, associated with a LED (Valo Cordless Ultradent®). Six points were irradiated on the back of the tongue with a distance of 1 cm between the points, considering the halo of light scattering and effectiveness of aPDT. The apparatus was previously calibrated at wavelength 395-480 nm for 20 seconds and energy of 9.6 J per point. The results of the halimetry were compared before, immediately after treatment and 7 days after. For the analysis of data from the Oral ChromaTM, the Friedman test was used for the intragroup analysis and the Kruskal Wallis test for the intergroup analysis. In all groups, there was a statistically significant difference between the initial sulfhydride value and the value immediately after the treatment (p <0.05). In Groups 1 and 3, there no was difference between the baseline value and the control of seven days. In Group 2, these times were not similar. There was no statistical difference between treatments. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018-12-18 |
dc.date.accessioned.fl_str_mv |
2021-11-04T15:49:23Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Gonçalves, Marcela Leticia Leal. Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado. 2018. 60 f. Tese( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo. |
dc.identifier.uri.fl_str_mv |
http://bibliotecatede.uninove.br/handle/tede/2660 |
identifier_str_mv |
Gonçalves, Marcela Leticia Leal. Efeito da terapia fotodinâmica antimicrobiana com urucum e led na redução da halitose– ensaio clínico controlado e randomizado. 2018. 60 f. Tese( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo. |
url |
http://bibliotecatede.uninove.br/handle/tede/2660 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.cnpq.fl_str_mv |
8765449414823306929 |
dc.relation.confidence.fl_str_mv |
600 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Nove de Julho |
dc.publisher.program.fl_str_mv |
Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde |
dc.publisher.initials.fl_str_mv |
UNINOVE |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Saúde |
publisher.none.fl_str_mv |
Universidade Nove de Julho |
dc.source.none.fl_str_mv |
reponame:Biblioteca Digital de Teses e Dissertações da Uninove instname:Universidade Nove de Julho (UNINOVE) instacron:UNINOVE |
instname_str |
Universidade Nove de Julho (UNINOVE) |
instacron_str |
UNINOVE |
institution |
UNINOVE |
reponame_str |
Biblioteca Digital de Teses e Dissertações da Uninove |
collection |
Biblioteca Digital de Teses e Dissertações da Uninove |
bitstream.url.fl_str_mv |
http://localhost:8080/tede/bitstream/tede/2660/2/Marcela+Leticia+Leal+Gon%C3%A7alves.pdf http://localhost:8080/tede/bitstream/tede/2660/1/license.txt |
bitstream.checksum.fl_str_mv |
b921ea7511ecd8cf2972977e2d7867be bd3efa91386c1718a7f26a329fdcb468 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
repository.name.fl_str_mv |
Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE) |
repository.mail.fl_str_mv |
bibliotecatede@uninove.br||bibliotecatede@uninove.br |
_version_ |
1811016884202504192 |