Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da Uninove |
Texto Completo: | http://bibliotecatede.uninove.br/handle/tede/1318 |
Resumo: | Halitosis is a term used to define the unpleasant breath that may have a systemic or oral origin. Volatile sulfur compounds produced by the Gramnegative bacteria mainly cause the bad breath. Using light - along with by chemical agents or not - is common to induce therapeutic and antimicrobial effects in the photodynamic therapy, and the antimicrobial effect happens only in the areas covered by the dye and irradiated by light. The aim of this study was to evaluate the antimicrobial effect of the photodynamic therapy in adolescent halitosis, analyzing the volatile sulfur compounds concentration, measured by gas chromatography (OralChromaTM). 45 adolescents were assessed and randomly divided (through controlled clinical study) into 3 groups that received different treatments: group 1 treatment with photodynamic therapy applied on the back (dorsum) region and on the middle third of the tongue, group 2 tongue scraper and group 3 treatment with tongue scraper and photodynamic therapy. The halitosis diagnosis was performed before and after the OralChroma treatment. The Kruskal-Wallis test was applied and compared with the Student-Newman-Keuls test. The ?? = 0.05 significance level was considered for all analysis. After the treatment, there was a statistically significant decline on all groups (p <0.001); however, the photodynamic therapy and tongue scraper treatment proved to be more efficient to fully reduce the hydrogen sulfides (median = 0). This study provides a new option for treating adolescent halitosis with immediate effects without mechanical aggression to the lingual papillae, which is common in the conventional treatment with tongue scrapers. |
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Bussadori, Sandra Kalilhttp://lattes.cnpq.br/4110914499694913Bussadori, Sandra Kalilhttp://lattes.cnpq.br/4110914499694913Navarro, Ricardo Scarparohttp://lattes.cnpq.br/9120674464635588Fran??a, Cristiane Mirandahttp://lattes.cnpq.br/3818545357716126http://lattes.cnpq.br/8152227658882149Lopes, R??bia Garcia2016-05-19T18:09:00Z2014-12-11Lopes, R??bia Garcia. Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose. 2014. 97 f. Disserta????o( Programa de P??s-Gradua????o em Biofot??nica Aplicada ??s Ci??ncias da Sa??de) - Universidade Nove de Julho, S??o Paulo.http://bibliotecatede.uninove.br/handle/tede/1318Halitosis is a term used to define the unpleasant breath that may have a systemic or oral origin. Volatile sulfur compounds produced by the Gramnegative bacteria mainly cause the bad breath. Using light - along with by chemical agents or not - is common to induce therapeutic and antimicrobial effects in the photodynamic therapy, and the antimicrobial effect happens only in the areas covered by the dye and irradiated by light. The aim of this study was to evaluate the antimicrobial effect of the photodynamic therapy in adolescent halitosis, analyzing the volatile sulfur compounds concentration, measured by gas chromatography (OralChromaTM). 45 adolescents were assessed and randomly divided (through controlled clinical study) into 3 groups that received different treatments: group 1 treatment with photodynamic therapy applied on the back (dorsum) region and on the middle third of the tongue, group 2 tongue scraper and group 3 treatment with tongue scraper and photodynamic therapy. The halitosis diagnosis was performed before and after the OralChroma treatment. The Kruskal-Wallis test was applied and compared with the Student-Newman-Keuls test. The ?? = 0.05 significance level was considered for all analysis. After the treatment, there was a statistically significant decline on all groups (p <0.001); however, the photodynamic therapy and tongue scraper treatment proved to be more efficient to fully reduce the hydrogen sulfides (median = 0). This study provides a new option for treating adolescent halitosis with immediate effects without mechanical aggression to the lingual papillae, which is common in the conventional treatment with tongue scrapers.A halitose ?? um termo utilizado para definir o odor desagrad??vel e f??tido que emana da boca, podendo apresentar origem sist??mica (10%) ou oral (90%). O mau odor ?? provocado principalmente por compostos sulforados vol??teis, produzido pela a????o de bact??rias Gram-negativas. A luz acompanhada ou n??o de agentes qu??micos tem sido usada para induzir efeitos terap??uticos e antimicrobianos na terapia fotodin??mica (TFD), sendo que o efeito antimicrobiano fica confinado apenas ??s ??reas cobertas pelo corante e irradiadas pela luz. O objetivo deste estudo foi avaliar o efeito antimicrobiano da TFD em adolescentes com halitose, pela an??lise da concentra????o de compostos sulforados vol??teis, mensurado por cromatografia gasosa (OralChroma TM). Por meio de estudo cl??nico controlado, 45 adolescentes foram avaliados e divididos aleatoriamente em 3 grupos que receberam tratamentos distintos: grupo 1 tratamento com TFD aplicada na regi??o de dorso e ter??o m??dio da l??ngua, grupo 2 raspador lingual e grupo 3 tratamento combinado de raspador lingual e TFD. O diagn??stico de halitose foi realizado antes e depois do tratamento pela cromatorgrafia gasosa. Foi aplicado o teste de Kruskal-Wallis para compara????o seguido do teste Student-Newman-Keuls. Para todas as an??lises foi considerado um n??vel de signific??ncia de ??=0,05. Ap??s o tratamento houve redu????o estatisticamente significante para todos os grupos (p < 0,001), contudo a associa????o da terapia fotodin??mica ao raspador lingual mostrou ser mais eficiente na redu????o total de sulfidretos (mediana=0). Conclui-se portanto, que esse estudo traz uma nova op????o de tratamento para halitose, com efeito imediato e sem agress??o mec??nica as papilas linguais comum ao tratamento convencional com raspadores.Submitted by Nadir Basilio (nadirsb@uninove.br) on 2016-05-19T18:09:00Z No. of bitstreams: 1 Rubia Garcia Lopes.pdf: 6178642 bytes, checksum: 787a2ca51a971a3c09bda8ef659636e1 (MD5)Made available in DSpace on 2016-05-19T18:09:00Z (GMT). No. of bitstreams: 1 Rubia Garcia Lopes.pdf: 6178642 bytes, checksum: 787a2ca51a971a3c09bda8ef659636e1 (MD5) Previous issue date: 2014-12-11application/pdfporUniversidade Nove de JulhoPrograma de P??s-Gradua????o em Biofot??nica Aplicada ??s Ci??ncias da Sa??deUNINOVEBrasilSa??dehalitoseterapia fotodin??micaadolescenteshalitosisphotodynamic therapyadolescentsCIENCIAS DA SAUDEEnsaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitosePhotodynamic therapy on teenagers with halitosis: a controlled clinical trialinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALRubia Garcia Lopes.pdfRubia Garcia Lopes.pdfapplication/pdf6178642http://localhost:8080/tede/bitstream/tede/1318/2/Rubia+Garcia+Lopes.pdf787a2ca51a971a3c09bda8ef659636e1MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/1318/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/13182016-05-19 15:09:00.344oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2016-05-19T18:09Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false |
dc.title.por.fl_str_mv |
Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose |
dc.title.alternative.eng.fl_str_mv |
Photodynamic therapy on teenagers with halitosis: a controlled clinical trial |
title |
Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose |
spellingShingle |
Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose Lopes, R??bia Garcia halitose terapia fotodin??mica adolescentes halitosis photodynamic therapy adolescents CIENCIAS DA SAUDE |
title_short |
Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose |
title_full |
Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose |
title_fullStr |
Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose |
title_full_unstemmed |
Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose |
title_sort |
Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose |
author |
Lopes, R??bia Garcia |
author_facet |
Lopes, R??bia Garcia |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Bussadori, Sandra Kalil |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/4110914499694913 |
dc.contributor.referee1.fl_str_mv |
Bussadori, Sandra Kalil |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/4110914499694913 |
dc.contributor.referee2.fl_str_mv |
Navarro, Ricardo Scarparo |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/9120674464635588 |
dc.contributor.referee3.fl_str_mv |
Fran??a, Cristiane Miranda |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/3818545357716126 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/8152227658882149 |
dc.contributor.author.fl_str_mv |
Lopes, R??bia Garcia |
contributor_str_mv |
Bussadori, Sandra Kalil Bussadori, Sandra Kalil Navarro, Ricardo Scarparo Fran??a, Cristiane Miranda |
dc.subject.por.fl_str_mv |
halitose terapia fotodin??mica adolescentes halitosis photodynamic therapy adolescents |
topic |
halitose terapia fotodin??mica adolescentes halitosis photodynamic therapy adolescents CIENCIAS DA SAUDE |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
Halitosis is a term used to define the unpleasant breath that may have a systemic or oral origin. Volatile sulfur compounds produced by the Gramnegative bacteria mainly cause the bad breath. Using light - along with by chemical agents or not - is common to induce therapeutic and antimicrobial effects in the photodynamic therapy, and the antimicrobial effect happens only in the areas covered by the dye and irradiated by light. The aim of this study was to evaluate the antimicrobial effect of the photodynamic therapy in adolescent halitosis, analyzing the volatile sulfur compounds concentration, measured by gas chromatography (OralChromaTM). 45 adolescents were assessed and randomly divided (through controlled clinical study) into 3 groups that received different treatments: group 1 treatment with photodynamic therapy applied on the back (dorsum) region and on the middle third of the tongue, group 2 tongue scraper and group 3 treatment with tongue scraper and photodynamic therapy. The halitosis diagnosis was performed before and after the OralChroma treatment. The Kruskal-Wallis test was applied and compared with the Student-Newman-Keuls test. The ?? = 0.05 significance level was considered for all analysis. After the treatment, there was a statistically significant decline on all groups (p <0.001); however, the photodynamic therapy and tongue scraper treatment proved to be more efficient to fully reduce the hydrogen sulfides (median = 0). This study provides a new option for treating adolescent halitosis with immediate effects without mechanical aggression to the lingual papillae, which is common in the conventional treatment with tongue scrapers. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014-12-11 |
dc.date.accessioned.fl_str_mv |
2016-05-19T18:09:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Lopes, R??bia Garcia. Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose. 2014. 97 f. Disserta????o( Programa de P??s-Gradua????o em Biofot??nica Aplicada ??s Ci??ncias da Sa??de) - Universidade Nove de Julho, S??o Paulo. |
dc.identifier.uri.fl_str_mv |
http://bibliotecatede.uninove.br/handle/tede/1318 |
identifier_str_mv |
Lopes, R??bia Garcia. Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose. 2014. 97 f. Disserta????o( Programa de P??s-Gradua????o em Biofot??nica Aplicada ??s Ci??ncias da Sa??de) - Universidade Nove de Julho, S??o Paulo. |
url |
http://bibliotecatede.uninove.br/handle/tede/1318 |
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por |
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por |
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8765449414823306929 |
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openAccess |
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Universidade Nove de Julho |
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Programa de P??s-Gradua????o em Biofot??nica Aplicada ??s Ci??ncias da Sa??de |
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UNINOVE |
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Brasil |
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Sa??de |
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Universidade Nove de Julho |
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