Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose

Detalhes bibliográficos
Autor(a) principal: Lopes, R??bia Garcia
Data de Publicação: 2014
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da Uninove
Texto Completo: http://bibliotecatede.uninove.br/handle/tede/1318
Resumo: Halitosis is a term used to define the unpleasant breath that may have a systemic or oral origin. Volatile sulfur compounds produced by the Gramnegative bacteria mainly cause the bad breath. Using light - along with by chemical agents or not - is common to induce therapeutic and antimicrobial effects in the photodynamic therapy, and the antimicrobial effect happens only in the areas covered by the dye and irradiated by light. The aim of this study was to evaluate the antimicrobial effect of the photodynamic therapy in adolescent halitosis, analyzing the volatile sulfur compounds concentration, measured by gas chromatography (OralChromaTM). 45 adolescents were assessed and randomly divided (through controlled clinical study) into 3 groups that received different treatments: group 1 treatment with photodynamic therapy applied on the back (dorsum) region and on the middle third of the tongue, group 2 tongue scraper and group 3 treatment with tongue scraper and photodynamic therapy. The halitosis diagnosis was performed before and after the OralChroma treatment. The Kruskal-Wallis test was applied and compared with the Student-Newman-Keuls test. The ?? = 0.05 significance level was considered for all analysis. After the treatment, there was a statistically significant decline on all groups (p <0.001); however, the photodynamic therapy and tongue scraper treatment proved to be more efficient to fully reduce the hydrogen sulfides (median = 0). This study provides a new option for treating adolescent halitosis with immediate effects without mechanical aggression to the lingual papillae, which is common in the conventional treatment with tongue scrapers.
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spelling Bussadori, Sandra Kalilhttp://lattes.cnpq.br/4110914499694913Bussadori, Sandra Kalilhttp://lattes.cnpq.br/4110914499694913Navarro, Ricardo Scarparohttp://lattes.cnpq.br/9120674464635588Fran??a, Cristiane Mirandahttp://lattes.cnpq.br/3818545357716126http://lattes.cnpq.br/8152227658882149Lopes, R??bia Garcia2016-05-19T18:09:00Z2014-12-11Lopes, R??bia Garcia. Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose. 2014. 97 f. Disserta????o( Programa de P??s-Gradua????o em Biofot??nica Aplicada ??s Ci??ncias da Sa??de) - Universidade Nove de Julho, S??o Paulo.http://bibliotecatede.uninove.br/handle/tede/1318Halitosis is a term used to define the unpleasant breath that may have a systemic or oral origin. Volatile sulfur compounds produced by the Gramnegative bacteria mainly cause the bad breath. Using light - along with by chemical agents or not - is common to induce therapeutic and antimicrobial effects in the photodynamic therapy, and the antimicrobial effect happens only in the areas covered by the dye and irradiated by light. The aim of this study was to evaluate the antimicrobial effect of the photodynamic therapy in adolescent halitosis, analyzing the volatile sulfur compounds concentration, measured by gas chromatography (OralChromaTM). 45 adolescents were assessed and randomly divided (through controlled clinical study) into 3 groups that received different treatments: group 1 treatment with photodynamic therapy applied on the back (dorsum) region and on the middle third of the tongue, group 2 tongue scraper and group 3 treatment with tongue scraper and photodynamic therapy. The halitosis diagnosis was performed before and after the OralChroma treatment. The Kruskal-Wallis test was applied and compared with the Student-Newman-Keuls test. The ?? = 0.05 significance level was considered for all analysis. After the treatment, there was a statistically significant decline on all groups (p <0.001); however, the photodynamic therapy and tongue scraper treatment proved to be more efficient to fully reduce the hydrogen sulfides (median = 0). This study provides a new option for treating adolescent halitosis with immediate effects without mechanical aggression to the lingual papillae, which is common in the conventional treatment with tongue scrapers.A halitose ?? um termo utilizado para definir o odor desagrad??vel e f??tido que emana da boca, podendo apresentar origem sist??mica (10%) ou oral (90%). O mau odor ?? provocado principalmente por compostos sulforados vol??teis, produzido pela a????o de bact??rias Gram-negativas. A luz acompanhada ou n??o de agentes qu??micos tem sido usada para induzir efeitos terap??uticos e antimicrobianos na terapia fotodin??mica (TFD), sendo que o efeito antimicrobiano fica confinado apenas ??s ??reas cobertas pelo corante e irradiadas pela luz. O objetivo deste estudo foi avaliar o efeito antimicrobiano da TFD em adolescentes com halitose, pela an??lise da concentra????o de compostos sulforados vol??teis, mensurado por cromatografia gasosa (OralChroma TM). Por meio de estudo cl??nico controlado, 45 adolescentes foram avaliados e divididos aleatoriamente em 3 grupos que receberam tratamentos distintos: grupo 1 tratamento com TFD aplicada na regi??o de dorso e ter??o m??dio da l??ngua, grupo 2 raspador lingual e grupo 3 tratamento combinado de raspador lingual e TFD. O diagn??stico de halitose foi realizado antes e depois do tratamento pela cromatorgrafia gasosa. Foi aplicado o teste de Kruskal-Wallis para compara????o seguido do teste Student-Newman-Keuls. Para todas as an??lises foi considerado um n??vel de signific??ncia de ??=0,05. Ap??s o tratamento houve redu????o estatisticamente significante para todos os grupos (p < 0,001), contudo a associa????o da terapia fotodin??mica ao raspador lingual mostrou ser mais eficiente na redu????o total de sulfidretos (mediana=0). Conclui-se portanto, que esse estudo traz uma nova op????o de tratamento para halitose, com efeito imediato e sem agress??o mec??nica as papilas linguais comum ao tratamento convencional com raspadores.Submitted by Nadir Basilio (nadirsb@uninove.br) on 2016-05-19T18:09:00Z No. of bitstreams: 1 Rubia Garcia Lopes.pdf: 6178642 bytes, checksum: 787a2ca51a971a3c09bda8ef659636e1 (MD5)Made available in DSpace on 2016-05-19T18:09:00Z (GMT). No. of bitstreams: 1 Rubia Garcia Lopes.pdf: 6178642 bytes, checksum: 787a2ca51a971a3c09bda8ef659636e1 (MD5) Previous issue date: 2014-12-11application/pdfporUniversidade Nove de JulhoPrograma de P??s-Gradua????o em Biofot??nica Aplicada ??s Ci??ncias da Sa??deUNINOVEBrasilSa??dehalitoseterapia fotodin??micaadolescenteshalitosisphotodynamic therapyadolescentsCIENCIAS DA SAUDEEnsaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitosePhotodynamic therapy on teenagers with halitosis: a controlled clinical trialinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALRubia Garcia Lopes.pdfRubia Garcia Lopes.pdfapplication/pdf6178642http://localhost:8080/tede/bitstream/tede/1318/2/Rubia+Garcia+Lopes.pdf787a2ca51a971a3c09bda8ef659636e1MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/1318/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/13182016-05-19 15:09:00.344oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2016-05-19T18:09Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false
dc.title.por.fl_str_mv Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose
dc.title.alternative.eng.fl_str_mv Photodynamic therapy on teenagers with halitosis: a controlled clinical trial
title Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose
spellingShingle Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose
Lopes, R??bia Garcia
halitose
terapia fotodin??mica
adolescentes
halitosis
photodynamic therapy
adolescents
CIENCIAS DA SAUDE
title_short Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose
title_full Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose
title_fullStr Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose
title_full_unstemmed Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose
title_sort Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose
author Lopes, R??bia Garcia
author_facet Lopes, R??bia Garcia
author_role author
dc.contributor.advisor1.fl_str_mv Bussadori, Sandra Kalil
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/4110914499694913
dc.contributor.referee1.fl_str_mv Bussadori, Sandra Kalil
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/4110914499694913
dc.contributor.referee2.fl_str_mv Navarro, Ricardo Scarparo
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/9120674464635588
dc.contributor.referee3.fl_str_mv Fran??a, Cristiane Miranda
dc.contributor.referee3Lattes.fl_str_mv http://lattes.cnpq.br/3818545357716126
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/8152227658882149
dc.contributor.author.fl_str_mv Lopes, R??bia Garcia
contributor_str_mv Bussadori, Sandra Kalil
Bussadori, Sandra Kalil
Navarro, Ricardo Scarparo
Fran??a, Cristiane Miranda
dc.subject.por.fl_str_mv halitose
terapia fotodin??mica
adolescentes
halitosis
photodynamic therapy
adolescents
topic halitose
terapia fotodin??mica
adolescentes
halitosis
photodynamic therapy
adolescents
CIENCIAS DA SAUDE
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE
description Halitosis is a term used to define the unpleasant breath that may have a systemic or oral origin. Volatile sulfur compounds produced by the Gramnegative bacteria mainly cause the bad breath. Using light - along with by chemical agents or not - is common to induce therapeutic and antimicrobial effects in the photodynamic therapy, and the antimicrobial effect happens only in the areas covered by the dye and irradiated by light. The aim of this study was to evaluate the antimicrobial effect of the photodynamic therapy in adolescent halitosis, analyzing the volatile sulfur compounds concentration, measured by gas chromatography (OralChromaTM). 45 adolescents were assessed and randomly divided (through controlled clinical study) into 3 groups that received different treatments: group 1 treatment with photodynamic therapy applied on the back (dorsum) region and on the middle third of the tongue, group 2 tongue scraper and group 3 treatment with tongue scraper and photodynamic therapy. The halitosis diagnosis was performed before and after the OralChroma treatment. The Kruskal-Wallis test was applied and compared with the Student-Newman-Keuls test. The ?? = 0.05 significance level was considered for all analysis. After the treatment, there was a statistically significant decline on all groups (p <0.001); however, the photodynamic therapy and tongue scraper treatment proved to be more efficient to fully reduce the hydrogen sulfides (median = 0). This study provides a new option for treating adolescent halitosis with immediate effects without mechanical aggression to the lingual papillae, which is common in the conventional treatment with tongue scrapers.
publishDate 2014
dc.date.issued.fl_str_mv 2014-12-11
dc.date.accessioned.fl_str_mv 2016-05-19T18:09:00Z
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dc.identifier.citation.fl_str_mv Lopes, R??bia Garcia. Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose. 2014. 97 f. Disserta????o( Programa de P??s-Gradua????o em Biofot??nica Aplicada ??s Ci??ncias da Sa??de) - Universidade Nove de Julho, S??o Paulo.
dc.identifier.uri.fl_str_mv http://bibliotecatede.uninove.br/handle/tede/1318
identifier_str_mv Lopes, R??bia Garcia. Ensaio cl??nico controlado do uso da terapia fotodin??mica em adolescentes com halitose. 2014. 97 f. Disserta????o( Programa de P??s-Gradua????o em Biofot??nica Aplicada ??s Ci??ncias da Sa??de) - Universidade Nove de Julho, S??o Paulo.
url http://bibliotecatede.uninove.br/handle/tede/1318
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dc.publisher.initials.fl_str_mv UNINOVE
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Sa??de
publisher.none.fl_str_mv Universidade Nove de Julho
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