Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating rats

Detalhes bibliográficos
Autor(a) principal: Habr,Soraya Ferreira
Data de Publicação: 2011
Outros Autores: Bernardi,Maria Martha, Conceição,Isaltino Marcelo, Freitas,Thalma Ariani, Felicio,Luciano Freitas
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Psychology & Neuroscience (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882011000100013
Resumo: In adult female mammals, reproductive experience (e.g., mating, pregnancy, parturition, and lactation) has long-term behavioral, endocrine, and neurochemical implications. This experience causes behavioral and neurochemical changes that involve several brain areas important for the expression of maternal behavior. The present study showed that lactating rats exhibited reduced general locomotor activity in the open field test compared with virgin animals. Our hypothesis was that nucleus accumbens dopamine, which regulates maternal behavior in lactating rats, is also involved in the low expression of maternal locomotion in the open field test observed during the early stages of lactation and reflects decreased motivation. Initially we compared open field behavior in virgin and lactating rats to confirm our previous data. Thus, the in vivo release of dopamine in the nucleus accumbens in virgin and lactating female rats was measured. Perfusate concentrations of extracellular dopamine and its metabolites showed no differences between virgin and lactating rats. Thus, the reduced general activity observed in lactating rats might not be related to intra-nucleus accumbens dopamine control.
id PUCRJ-1_3038572f4956422a612fb26c2c8261b3
oai_identifier_str oai:scielo:S1983-32882011000100013
network_acronym_str PUCRJ-1
network_name_str Psychology & Neuroscience (Online)
repository_id_str
spelling Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating ratsmaternal behaviorvirgin ratslactating ratsnucleus accumbensdopamineIn adult female mammals, reproductive experience (e.g., mating, pregnancy, parturition, and lactation) has long-term behavioral, endocrine, and neurochemical implications. This experience causes behavioral and neurochemical changes that involve several brain areas important for the expression of maternal behavior. The present study showed that lactating rats exhibited reduced general locomotor activity in the open field test compared with virgin animals. Our hypothesis was that nucleus accumbens dopamine, which regulates maternal behavior in lactating rats, is also involved in the low expression of maternal locomotion in the open field test observed during the early stages of lactation and reflects decreased motivation. Initially we compared open field behavior in virgin and lactating rats to confirm our previous data. Thus, the in vivo release of dopamine in the nucleus accumbens in virgin and lactating female rats was measured. Perfusate concentrations of extracellular dopamine and its metabolites showed no differences between virgin and lactating rats. Thus, the reduced general activity observed in lactating rats might not be related to intra-nucleus accumbens dopamine control.Pontificia Universidade Católica do Rio de JaneiroUniversidade de BrasíliaUniversidade de São Paulo2011-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882011000100013Psychology & Neuroscience v.4 n.1 2011reponame:Psychology & Neuroscience (Online)instname:Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)instacron:PUCRJ10.3922/j.psns.2011.1.013info:eu-repo/semantics/openAccessHabr,Soraya FerreiraBernardi,Maria MarthaConceição,Isaltino MarceloFreitas,Thalma ArianiFelicio,Luciano Freitaseng2011-08-23T00:00:00Zoai:scielo:S1983-32882011000100013Revistahttps://www.apa.org/pubs/journals/pnePRIhttps://old.scielo.br/oai/scielo-oai.phppsycneuro@psycneuro.org1983-32881984-3054opendoar:2011-08-23T00:00Psychology & Neuroscience (Online) - Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)false
dc.title.none.fl_str_mv Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating rats
title Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating rats
spellingShingle Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating rats
Habr,Soraya Ferreira
maternal behavior
virgin rats
lactating rats
nucleus accumbens
dopamine
title_short Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating rats
title_full Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating rats
title_fullStr Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating rats
title_full_unstemmed Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating rats
title_sort Open field behavior and intra-nucleus accumbens dopamine release in vivo in virgin and lactating rats
author Habr,Soraya Ferreira
author_facet Habr,Soraya Ferreira
Bernardi,Maria Martha
Conceição,Isaltino Marcelo
Freitas,Thalma Ariani
Felicio,Luciano Freitas
author_role author
author2 Bernardi,Maria Martha
Conceição,Isaltino Marcelo
Freitas,Thalma Ariani
Felicio,Luciano Freitas
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Habr,Soraya Ferreira
Bernardi,Maria Martha
Conceição,Isaltino Marcelo
Freitas,Thalma Ariani
Felicio,Luciano Freitas
dc.subject.por.fl_str_mv maternal behavior
virgin rats
lactating rats
nucleus accumbens
dopamine
topic maternal behavior
virgin rats
lactating rats
nucleus accumbens
dopamine
description In adult female mammals, reproductive experience (e.g., mating, pregnancy, parturition, and lactation) has long-term behavioral, endocrine, and neurochemical implications. This experience causes behavioral and neurochemical changes that involve several brain areas important for the expression of maternal behavior. The present study showed that lactating rats exhibited reduced general locomotor activity in the open field test compared with virgin animals. Our hypothesis was that nucleus accumbens dopamine, which regulates maternal behavior in lactating rats, is also involved in the low expression of maternal locomotion in the open field test observed during the early stages of lactation and reflects decreased motivation. Initially we compared open field behavior in virgin and lactating rats to confirm our previous data. Thus, the in vivo release of dopamine in the nucleus accumbens in virgin and lactating female rats was measured. Perfusate concentrations of extracellular dopamine and its metabolites showed no differences between virgin and lactating rats. Thus, the reduced general activity observed in lactating rats might not be related to intra-nucleus accumbens dopamine control.
publishDate 2011
dc.date.none.fl_str_mv 2011-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882011000100013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882011000100013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.3922/j.psns.2011.1.013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Pontificia Universidade Católica do Rio de Janeiro
Universidade de Brasília
Universidade de São Paulo
publisher.none.fl_str_mv Pontificia Universidade Católica do Rio de Janeiro
Universidade de Brasília
Universidade de São Paulo
dc.source.none.fl_str_mv Psychology & Neuroscience v.4 n.1 2011
reponame:Psychology & Neuroscience (Online)
instname:Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)
instacron:PUCRJ
instname_str Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)
instacron_str PUCRJ
institution PUCRJ
reponame_str Psychology & Neuroscience (Online)
collection Psychology & Neuroscience (Online)
repository.name.fl_str_mv Psychology & Neuroscience (Online) - Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)
repository.mail.fl_str_mv psycneuro@psycneuro.org
_version_ 1754821072410116096

Registros relacionados