Efeito do laser de baixa intensidade na prevenção e tratamento da mucosite bucal

• Autor(a) principal: Pinto, Tatiana Andrea Soares
• Data de Publicação: 2010
• Tipo de documento: Tese
• Idioma: por
• Título da fonte: Repositório Institucional PUCRS
• Texto Completo: http://hdl.handle.net/10923/454
• topic: ODONTOLOGIA; ESTOMATOLOGIA CLÍNICA; LASER - ODONTOLOGIA; MUCOSA BUCAL - LESÕES; QUIMIOTERAPIA; NEOPLASIAS

OBJECTIVES: This study compared the results obtained in the prevention and treatment of chemotherapy-induced oral mucositis using InGaAIP diode laser in two different protocols: therapeutic and prophylactic/therapeutic treatment. In addition, we evaluated changes in the clinical picture of pain before and after laser therapy in different degrees of mucositis. METHODS: Patients (n=14) treated with chemotherapy at Hospital São Lucas of Pontifícia Universidade Católica do Rio Grande do Sul, Brazil, with no previous mucositis, were randomized into a therapeutic group (group 1) and a prophylactic/therapeutic group (group 2). The occurrence of mucositis was evaluated in both groups and classified according to World Health Organization (WHO) criteria. After low level laser application in the treatment of mucositis, we compared pain intensity before and after laser therapy using the visual analog scale (VAS). RESULTS: Group 2 showed a lower degree of mucositis (p=0.004) and shorter time to remission (p=0.042) when compared to group 1. Pain intensity after laser therapy was significantly lower than before laser therapy in grade 2 (p=0.002) and grade 3 (p=0.005) mucositis. CONCLUSION: The use of low level laser irradiation in the prophylactic/therapeutic protocol, when compared to the therapeutic protocol, results in shorter healing time and greater control over the severity of chemotherapy-induced oral mucositis.