Influence of smoking on salivary amylase activity and glycemic curve

• Autor(a) principal: MORIEL, Patricia
• Data de Publicação: 2023
• Outros Autores: Lima MADUREIRA, Hermes, Yuuko UWAGOYA, Áurea Kátia, WLIAN, Luana, de Carvalho PINCINATO, Eder
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista de Nutrição
• Texto Completo: https://periodicos.puc-campinas.edu.br/nutricao/article/view/9394
• topic: Salivate alpha-amylases; Blood glucose; Digestive system bodisses; Tabaco; Alfa-amilases salivares; Glicemia; Processos do sistema digest´ório; Tabaco

ObjectiveThe objective of this study was to determine salivary amylase activity and its relationship with glycemia before and after smokers and nonsmokers ingested carbohydrates..Since cigarette smoke reduces salivary amylase activity in vitro, it may affect dietary carbohydrate absorption. MethodsTwenty volunteers participated in this study, 10 smokers and 10 nonsmokers. Samples of saliva were collected before and after the smokers had a cigarette and glycemia was determined before and after the ingestion of 72g of carbohydrates. Glycemia was measured 0, 15, 30, 60 and 120 minutes after carbohydrate intake. Salivary amylase activity was determined by commercial kits. Glycemia was determined by a glucometer (Accu-Chek-Roche). The paired t-test was used for the statistical analyses, done by the software Sigmastat, with p<0.05. ResultsGlycemia 15, 30, 60 and 90 minutes after carbohydrate intake rose 3.9%, 11.9%, 34.8% and 22.7% in nonsmokers and 4.9%, 6.5%, 13.8% and 9.7% in smokers, respectively. The peak glucose absorption in nonsmokers was 21.0% greater than in smokers. Salivary amylase activity before and after eating was 75.0% smaller in smokers. ConclusionThese results suggest that smoking inhibits amylase and has a negative impact on the digestion/absorption of carbohydrates, consequently in blood glucose levels, thereby reducing the amount of energy absorbed.