Drug-nutrient interaction: a review
Autor(a) principal: | |
---|---|
Data de Publicação: | 2002 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista de Nutrição |
Texto Completo: | https://periodicos.puc-campinas.edu.br/nutricao/article/view/9080 |
Resumo: | Diet influences the whole life cycle, supplying nutrients required to maintain the human body. Functional and/or structural alterations, caused by diseases and acute or chronic infections, lead to the use of drugs in order to restore the health. The oral route is preferred for drug administration, owing to safety and convenience, among other reasons. The drug-nutrient interaction phenomenon can occur before or during gastrointestinal absorption, during distribution and storage in the tissues, in the biotransformation process, or even during excretion. Thus, to know the drugs whose rate of absorption and/or absorbed amount can be affected in the presence of food, as well as those that are not affected, is of fundamental importance. On the other hand, anumber of commonly used drugs, including antibiotics, antacids and laxatives, can cause malabsorption of nutrients. Therefore, the objective of this article is to present a review of the several aspects involved in the drug-nutrient interaction. |
id |
PUC_CAMP-2_750dc246e3455be0b6080fd1da006d93 |
---|---|
oai_identifier_str |
oai:ojs.periodicos.puc-campinas.edu.br:article/9080 |
network_acronym_str |
PUC_CAMP-2 |
network_name_str |
Revista de Nutrição |
repository_id_str |
|
spelling |
Drug-nutrient interaction: a reviewInteração fármaco-nutriente: uma revisãofood-drug interactionsclinical pharmacologyabsorptionfooddrugsinteração alimento-drogafarmacologia clínicaabsorçãoalimentosmedicamentosDiet influences the whole life cycle, supplying nutrients required to maintain the human body. Functional and/or structural alterations, caused by diseases and acute or chronic infections, lead to the use of drugs in order to restore the health. The oral route is preferred for drug administration, owing to safety and convenience, among other reasons. The drug-nutrient interaction phenomenon can occur before or during gastrointestinal absorption, during distribution and storage in the tissues, in the biotransformation process, or even during excretion. Thus, to know the drugs whose rate of absorption and/or absorbed amount can be affected in the presence of food, as well as those that are not affected, is of fundamental importance. On the other hand, anumber of commonly used drugs, including antibiotics, antacids and laxatives, can cause malabsorption of nutrients. Therefore, the objective of this article is to present a review of the several aspects involved in the drug-nutrient interaction.A dieta influencia todos os estágios do ciclo da vida, fornecendo nutrientes necessários ao sustento do corpo humano. Alterações de ordem funcional e/ou estrutural, provocadas por doenças e infecções agudas ou crônicas, levam à utilização de medicamentos, cujo objetivo é restaurar a saúde. A via preferencial escolhida para a sua administração é a oral, entre outras razões, por sua comodidade e segurança. O fenômeno de interação fármaco-nutriente pode surgir antes ou durante a absorção gastrintestinal, durante a distribuição e armazenamento nos tecidos, no processo de biotransformação ou mesmo durante a excreção. Assim, é de importância fundamental conhecer os fármacos cuja velocidade de absorção e/ou quantidade absorvida podem ser afetadas na presença de alimentos, bem como aqueles que não são afetados. Por outro lado, muitos deles, incluindo antibióticos, antiácidos e laxativos podem causar má absorção de nutrientes. Portanto, o objetivo do presente artigo é apresentar uma revisão dos diversos aspectos envolvidos na interação fármaco-nutriente.Núcleo de Editoração – PUC-Campinas2002-08-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.puc-campinas.edu.br/nutricao/article/view/9080Brazilian Journal of Nutrition; Vol. 15 No. 2 (2002): Revista de NutriçãoRevista de Nutrição; Vol. 15 Núm. 2 (2002): Revista de NutriçãoRevista de Nutrição; v. 15 n. 2 (2002): Revista de Nutrição1678-9865reponame:Revista de Nutriçãoinstname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)instacron:PUC_CAMPporhttps://periodicos.puc-campinas.edu.br/nutricao/article/view/9080/6472Copyright (c) 2023 Mirian Ribeiro Leite MOURA, Felix Guillermo Reyes REYEShttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRibeiro Leite MOURA, Mirian Reyes REYES, Felix Guillermo2024-04-08T13:38:23Zoai:ojs.periodicos.puc-campinas.edu.br:article/9080Revistahttp://www.scielo.br/rnPRIhttps://periodicos.puc-campinas.edu.br/nutricao/oai||sbi.submissionrn@puc-campinas.edu.br1678-98651415-5273opendoar:2024-04-08T13:38:23Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)false |
dc.title.none.fl_str_mv |
Drug-nutrient interaction: a review Interação fármaco-nutriente: uma revisão |
title |
Drug-nutrient interaction: a review |
spellingShingle |
Drug-nutrient interaction: a review Ribeiro Leite MOURA, Mirian food-drug interactions clinical pharmacology absorption food drugs interação alimento-droga farmacologia clínica absorção alimentos medicamentos |
title_short |
Drug-nutrient interaction: a review |
title_full |
Drug-nutrient interaction: a review |
title_fullStr |
Drug-nutrient interaction: a review |
title_full_unstemmed |
Drug-nutrient interaction: a review |
title_sort |
Drug-nutrient interaction: a review |
author |
Ribeiro Leite MOURA, Mirian |
author_facet |
Ribeiro Leite MOURA, Mirian Reyes REYES, Felix Guillermo |
author_role |
author |
author2 |
Reyes REYES, Felix Guillermo |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Ribeiro Leite MOURA, Mirian Reyes REYES, Felix Guillermo |
dc.subject.por.fl_str_mv |
food-drug interactions clinical pharmacology absorption food drugs interação alimento-droga farmacologia clínica absorção alimentos medicamentos |
topic |
food-drug interactions clinical pharmacology absorption food drugs interação alimento-droga farmacologia clínica absorção alimentos medicamentos |
description |
Diet influences the whole life cycle, supplying nutrients required to maintain the human body. Functional and/or structural alterations, caused by diseases and acute or chronic infections, lead to the use of drugs in order to restore the health. The oral route is preferred for drug administration, owing to safety and convenience, among other reasons. The drug-nutrient interaction phenomenon can occur before or during gastrointestinal absorption, during distribution and storage in the tissues, in the biotransformation process, or even during excretion. Thus, to know the drugs whose rate of absorption and/or absorbed amount can be affected in the presence of food, as well as those that are not affected, is of fundamental importance. On the other hand, anumber of commonly used drugs, including antibiotics, antacids and laxatives, can cause malabsorption of nutrients. Therefore, the objective of this article is to present a review of the several aspects involved in the drug-nutrient interaction. |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002-08-25 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.puc-campinas.edu.br/nutricao/article/view/9080 |
url |
https://periodicos.puc-campinas.edu.br/nutricao/article/view/9080 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.puc-campinas.edu.br/nutricao/article/view/9080/6472 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2023 Mirian Ribeiro Leite MOURA, Felix Guillermo Reyes REYES https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2023 Mirian Ribeiro Leite MOURA, Felix Guillermo Reyes REYES https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Núcleo de Editoração – PUC-Campinas |
publisher.none.fl_str_mv |
Núcleo de Editoração – PUC-Campinas |
dc.source.none.fl_str_mv |
Brazilian Journal of Nutrition; Vol. 15 No. 2 (2002): Revista de Nutrição Revista de Nutrição; Vol. 15 Núm. 2 (2002): Revista de Nutrição Revista de Nutrição; v. 15 n. 2 (2002): Revista de Nutrição 1678-9865 reponame:Revista de Nutrição instname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS) instacron:PUC_CAMP |
instname_str |
Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS) |
instacron_str |
PUC_CAMP |
institution |
PUC_CAMP |
reponame_str |
Revista de Nutrição |
collection |
Revista de Nutrição |
repository.name.fl_str_mv |
Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS) |
repository.mail.fl_str_mv |
||sbi.submissionrn@puc-campinas.edu.br |
_version_ |
1799126071446077440 |