ETHICAL AND LEGAL IMPLICATIONS OF GENE EDITING
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | spa |
Título da fonte: | Revista da Faculdade Mineira de Direito (Online) |
Texto Completo: | http://periodicos.pucminas.br/index.php/Direito/article/view/24917 |
Resumo: | The aim of this paper is to address, from the areas of Ethics and Law, the scope of one of the biotechnologies that is generating most impact in the doctrine due to its potential clinical application. This is due to the infinite possibilities promised by gene editing, and more specifically, its famous tool: CRISPR/Cas9. Among its possible applications are the repair of serious diseases in human germinal cells, preventing their eventual transmission to descendants. However, it could, as one of the many works coordinated and co-written by our mentor, Professor Romeo Casabona, rightly calls it, go "beyond health", giving rise to eugenic reminiscences, which would be represented by human enhancement. Consequently, we will analyse, on the one hand, the ethical acceptability of gene therapy in the face of improvement, in consideration of the bioethical principles of autonomy, beneficence, non-maleficence and justice. On the other, will think in the effect that gene editing indiscriminate use could have on fundamental rights, especially in terms of human dignity, equality and identity, as well as on the unaltered genetic heritage and the responsibilities towards future generations, which Professor Romeo has been a pioneer in envisaging. |
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ETHICAL AND LEGAL IMPLICATIONS OF GENE EDITINGIMPLICACIONES ÉTICO-JURÍDICAS DE LA EDICIÓN DE GENESCRISPR/Cas9Germinal gene editingHuman enhancementGene therapy.CRISPR/Cas9Edición genética germinalMejora humanaTerapia génica.The aim of this paper is to address, from the areas of Ethics and Law, the scope of one of the biotechnologies that is generating most impact in the doctrine due to its potential clinical application. This is due to the infinite possibilities promised by gene editing, and more specifically, its famous tool: CRISPR/Cas9. Among its possible applications are the repair of serious diseases in human germinal cells, preventing their eventual transmission to descendants. However, it could, as one of the many works coordinated and co-written by our mentor, Professor Romeo Casabona, rightly calls it, go "beyond health", giving rise to eugenic reminiscences, which would be represented by human enhancement. Consequently, we will analyse, on the one hand, the ethical acceptability of gene therapy in the face of improvement, in consideration of the bioethical principles of autonomy, beneficence, non-maleficence and justice. On the other, will think in the effect that gene editing indiscriminate use could have on fundamental rights, especially in terms of human dignity, equality and identity, as well as on the unaltered genetic heritage and the responsibilities towards future generations, which Professor Romeo has been a pioneer in envisaging.El presente trabajo tiene por objeto abordar, desde las áreas de la Ética y el Derecho, el alcance de una de las biotecnologías que más impacto está generando en la literatura ante su potencial aplicación clínica. Ello obedece a las infinitas posibilidades que promete la edición de genes, y, más concretamente, su afamada herramienta CRISPR/Cas9, entre las que destaca la reparación de enfermedades graves en células germinales humanas, pudiendo evitar su eventual transmisión a los descendientes. No obstante, podría, como titula acertadamente una de las múltiples obras coordinadas y co-redactadas por nuestro maestro, el Profesor Romeo Casabona, ir “más allá de la salud”, dando lugar a reminiscencias eugenésicas, y que vendrían representadas por medio de la mejora humana. Consecuentemente, se analizará, por un lado, la aceptabilidad desde el punto de vista ético de la terapia génica frente a la mejora, en ponderación con los principios bioéticos de autonomía, beneficencia, no maleficencia y justicia; y, por otro, la afectación que para los derechos fundamentales pudiera suponer su uso indiscriminado, muy especialmente, en cuanto a la dignidad humana, igualdad e identidad, así como al patrimonio genético inalterado y las responsabilidades para con las generaciones futuras, y de los que el Profesor Romeo ha sido pionero en alertar.Editora PUC Minas2020-12-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://periodicos.pucminas.br/index.php/Direito/article/view/2491710.5752/P.2318-7999.2020v23n46p141-160Revista da Faculdade Mineira de Direito; v. 23 n. 46 (2020): REVISTA DA FACULDADE MINEIRA DE DIREITO - PUC MINAS; 141-1602318-79991808-9429reponame:Revista da Faculdade Mineira de Direito (Online)instname:Pontifícia Universidade Católica de Minas Gerais (PUC Minas)instacron:PUC_MINSspahttp://periodicos.pucminas.br/index.php/Direito/article/view/24917/17446Copyright (c) 2020 Revista da Faculdade Mineira de Direitoinfo:eu-repo/semantics/openAccessDuardo Sánchez, AliuskaPayán Ellacuria, Ekain2022-03-10T13:54:34Zoai:ojs.pkp.sfu.ca:article/24917Revistahttp://periodicos.pucminas.br/index.php/Direito/indexPRIhttp://periodicos.pucminas.br/index.php/Direito/oai||revistafmd@pucminas.br2318-79991808-9429opendoar:2022-03-10T13:54:34Revista da Faculdade Mineira de Direito (Online) - Pontifícia Universidade Católica de Minas Gerais (PUC Minas)false |
dc.title.none.fl_str_mv |
ETHICAL AND LEGAL IMPLICATIONS OF GENE EDITING IMPLICACIONES ÉTICO-JURÍDICAS DE LA EDICIÓN DE GENES |
title |
ETHICAL AND LEGAL IMPLICATIONS OF GENE EDITING |
spellingShingle |
ETHICAL AND LEGAL IMPLICATIONS OF GENE EDITING Duardo Sánchez, Aliuska CRISPR/Cas9 Germinal gene editing Human enhancement Gene therapy. CRISPR/Cas9 Edición genética germinal Mejora humana Terapia génica. |
title_short |
ETHICAL AND LEGAL IMPLICATIONS OF GENE EDITING |
title_full |
ETHICAL AND LEGAL IMPLICATIONS OF GENE EDITING |
title_fullStr |
ETHICAL AND LEGAL IMPLICATIONS OF GENE EDITING |
title_full_unstemmed |
ETHICAL AND LEGAL IMPLICATIONS OF GENE EDITING |
title_sort |
ETHICAL AND LEGAL IMPLICATIONS OF GENE EDITING |
author |
Duardo Sánchez, Aliuska |
author_facet |
Duardo Sánchez, Aliuska Payán Ellacuria, Ekain |
author_role |
author |
author2 |
Payán Ellacuria, Ekain |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Duardo Sánchez, Aliuska Payán Ellacuria, Ekain |
dc.subject.por.fl_str_mv |
CRISPR/Cas9 Germinal gene editing Human enhancement Gene therapy. CRISPR/Cas9 Edición genética germinal Mejora humana Terapia génica. |
topic |
CRISPR/Cas9 Germinal gene editing Human enhancement Gene therapy. CRISPR/Cas9 Edición genética germinal Mejora humana Terapia génica. |
description |
The aim of this paper is to address, from the areas of Ethics and Law, the scope of one of the biotechnologies that is generating most impact in the doctrine due to its potential clinical application. This is due to the infinite possibilities promised by gene editing, and more specifically, its famous tool: CRISPR/Cas9. Among its possible applications are the repair of serious diseases in human germinal cells, preventing their eventual transmission to descendants. However, it could, as one of the many works coordinated and co-written by our mentor, Professor Romeo Casabona, rightly calls it, go "beyond health", giving rise to eugenic reminiscences, which would be represented by human enhancement. Consequently, we will analyse, on the one hand, the ethical acceptability of gene therapy in the face of improvement, in consideration of the bioethical principles of autonomy, beneficence, non-maleficence and justice. On the other, will think in the effect that gene editing indiscriminate use could have on fundamental rights, especially in terms of human dignity, equality and identity, as well as on the unaltered genetic heritage and the responsibilities towards future generations, which Professor Romeo has been a pioneer in envisaging. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-07 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://periodicos.pucminas.br/index.php/Direito/article/view/24917 10.5752/P.2318-7999.2020v23n46p141-160 |
url |
http://periodicos.pucminas.br/index.php/Direito/article/view/24917 |
identifier_str_mv |
10.5752/P.2318-7999.2020v23n46p141-160 |
dc.language.iso.fl_str_mv |
spa |
language |
spa |
dc.relation.none.fl_str_mv |
http://periodicos.pucminas.br/index.php/Direito/article/view/24917/17446 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Revista da Faculdade Mineira de Direito info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Revista da Faculdade Mineira de Direito |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Editora PUC Minas |
publisher.none.fl_str_mv |
Editora PUC Minas |
dc.source.none.fl_str_mv |
Revista da Faculdade Mineira de Direito; v. 23 n. 46 (2020): REVISTA DA FACULDADE MINEIRA DE DIREITO - PUC MINAS; 141-160 2318-7999 1808-9429 reponame:Revista da Faculdade Mineira de Direito (Online) instname:Pontifícia Universidade Católica de Minas Gerais (PUC Minas) instacron:PUC_MINS |
instname_str |
Pontifícia Universidade Católica de Minas Gerais (PUC Minas) |
instacron_str |
PUC_MINS |
institution |
PUC_MINS |
reponame_str |
Revista da Faculdade Mineira de Direito (Online) |
collection |
Revista da Faculdade Mineira de Direito (Online) |
repository.name.fl_str_mv |
Revista da Faculdade Mineira de Direito (Online) - Pontifícia Universidade Católica de Minas Gerais (PUC Minas) |
repository.mail.fl_str_mv |
||revistafmd@pucminas.br |
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1799124789540945920 |