Influence of variable concentration of ethanol intake on alveolar bone loos in rats periodontitis model

Detalhes bibliográficos
Autor(a) principal: Souza, Daniela Martins de
Data de Publicação: 2014
Outros Autores: Rocha, Rosilene Fernandes da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista odonto ciência (Online)
Texto Completo: https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/13029
Resumo: Objective: The aim of this study was to morphometrically evaluate the effect of variable concentration of ethanol consumption on alveolar bone loss associated with ligature-induce periodontitis in rats.Methods: Thirty-six male rats (Wistar, 120 days-old) were randomly divided into four groups of nine animals each. The rats received daily rat chow and administration of water free liquid diet (control), 10% alcohol diet (10% ethanol), 20% alcohol diet (20% ethanol) or 30% alcohol diet (30% ethanol). After anesthesia, cotton ligatures were placed around the cervix of the right upper second molar, leaving the contralateral teeth unligated. After 8 weeks, the rats were sacrificed and the maxillary bones were removed and alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at the buccal site of the right upper second molar.Results: Unligated groups showed no significant differences between each other (p>0.05). In ligated groups, rats receiving 10%, 20% and 30% ethanol showed significantly greater bone loss compared to control rats.Conclusion: These results demonstrate that variable concentration of ethanol consumption may increase alveolar bone loss in male rats, independent of dose used, associated with ligature-induce periodontitis in rats.
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spelling Influence of variable concentration of ethanol intake on alveolar bone loos in rats periodontitis modelInfluência da variável concentração de etanol ingerido na perda óssea alveolar em modelo de periodontite em ratosEthanolalveolar bone lossperiodontitisratsperiodontal medicineEthanolperda óssea alveolarperiodontiteratosObjective: The aim of this study was to morphometrically evaluate the effect of variable concentration of ethanol consumption on alveolar bone loss associated with ligature-induce periodontitis in rats.Methods: Thirty-six male rats (Wistar, 120 days-old) were randomly divided into four groups of nine animals each. The rats received daily rat chow and administration of water free liquid diet (control), 10% alcohol diet (10% ethanol), 20% alcohol diet (20% ethanol) or 30% alcohol diet (30% ethanol). After anesthesia, cotton ligatures were placed around the cervix of the right upper second molar, leaving the contralateral teeth unligated. After 8 weeks, the rats were sacrificed and the maxillary bones were removed and alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at the buccal site of the right upper second molar.Results: Unligated groups showed no significant differences between each other (p>0.05). In ligated groups, rats receiving 10%, 20% and 30% ethanol showed significantly greater bone loss compared to control rats.Conclusion: These results demonstrate that variable concentration of ethanol consumption may increase alveolar bone loss in male rats, independent of dose used, associated with ligature-induce periodontitis in rats.Objetivo: O propósito deste estudo foi avaliar morfometricamente o efeito de variáveis concentrações de etanol consumido, na perda óssea alveolar associada a periodontite induzida por ligadura em ratos.Metodologia: Trinta e seis ratos machos (wistar, 120 dias) foram randomicamente divididos em quatro grupos de nove animais. Os ratos receberam diariamente ração e água livremente (controle), 10% de álcool na dieta (10% etanol), 20% de álcool na dieta (20% etanol) ou 30% de álcool na dieta (30% etanol). Após anestesia, ligaduras de algodão foram colocadas entorno da cervical do segundo molar superior direito, mantendo o dente contra lateral sem ligadura. Após 8 semanas, os ratos foram sacrificados e o osso maxilar foi removido e a perda óssea alveolar foi analisada pela mensuração da distancia entre a junção cemento-esmalte e a crista óssea alveolar na face vestibular do segundo molar superior direito.Resultados: Os grupos sem ligadura não apresentaram diferença estatística entre eles (p>0,05). Nos grupos com ligadura, os ratos que receberam 10%, 20% e 30% de etanol apresentaram perda óssea significativamente maior que os ratos controle.Conclusão: Estes resultados demonstram que variáveis concentrações de etanol podem aumentar a perda óssea alveolar em ratos machos, independente da dose usada, associado a periodontite induzida por ligadura em ratos.EDIPUCRS - Editora Universitária da PUCRS2014-07-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleResearch in ratsapplication/pdfhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/1302910.15448/1980-6523.2014.3.13029Revista Odonto Ciência; Vol. 29 No. 3 (2014); 76-80Revista Odonto Ciência; v. 29 n. 3 (2014); 76-801980-65230102-946010.15448/1980-6523.2014.3reponame:Revista odonto ciência (Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSenghttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/13029/13369Copyright (c) 2015 Revista Odonto Ciência (Journal of Dental Science)info:eu-repo/semantics/openAccessSouza, Daniela Martins deRocha, Rosilene Fernandes da2015-10-21T16:34:51Zoai:ojs.revistaseletronicas.pucrs.br:article/13029Revistahttps://revistaseletronicas.pucrs.br/ojs/index.php/foPRIhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/oai||odontociencia@pucrs.br1980-65230102-9460opendoar:2015-10-21T16:34:51Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Influence of variable concentration of ethanol intake on alveolar bone loos in rats periodontitis model
Influência da variável concentração de etanol ingerido na perda óssea alveolar em modelo de periodontite em ratos
title Influence of variable concentration of ethanol intake on alveolar bone loos in rats periodontitis model
spellingShingle Influence of variable concentration of ethanol intake on alveolar bone loos in rats periodontitis model
Souza, Daniela Martins de
Ethanol
alveolar bone loss
periodontitis
rats
periodontal medicine
Ethanol
perda óssea alveolar
periodontite
ratos
title_short Influence of variable concentration of ethanol intake on alveolar bone loos in rats periodontitis model
title_full Influence of variable concentration of ethanol intake on alveolar bone loos in rats periodontitis model
title_fullStr Influence of variable concentration of ethanol intake on alveolar bone loos in rats periodontitis model
title_full_unstemmed Influence of variable concentration of ethanol intake on alveolar bone loos in rats periodontitis model
title_sort Influence of variable concentration of ethanol intake on alveolar bone loos in rats periodontitis model
author Souza, Daniela Martins de
author_facet Souza, Daniela Martins de
Rocha, Rosilene Fernandes da
author_role author
author2 Rocha, Rosilene Fernandes da
author2_role author
dc.contributor.author.fl_str_mv Souza, Daniela Martins de
Rocha, Rosilene Fernandes da
dc.subject.por.fl_str_mv Ethanol
alveolar bone loss
periodontitis
rats
periodontal medicine
Ethanol
perda óssea alveolar
periodontite
ratos
topic Ethanol
alveolar bone loss
periodontitis
rats
periodontal medicine
Ethanol
perda óssea alveolar
periodontite
ratos
description Objective: The aim of this study was to morphometrically evaluate the effect of variable concentration of ethanol consumption on alveolar bone loss associated with ligature-induce periodontitis in rats.Methods: Thirty-six male rats (Wistar, 120 days-old) were randomly divided into four groups of nine animals each. The rats received daily rat chow and administration of water free liquid diet (control), 10% alcohol diet (10% ethanol), 20% alcohol diet (20% ethanol) or 30% alcohol diet (30% ethanol). After anesthesia, cotton ligatures were placed around the cervix of the right upper second molar, leaving the contralateral teeth unligated. After 8 weeks, the rats were sacrificed and the maxillary bones were removed and alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at the buccal site of the right upper second molar.Results: Unligated groups showed no significant differences between each other (p>0.05). In ligated groups, rats receiving 10%, 20% and 30% ethanol showed significantly greater bone loss compared to control rats.Conclusion: These results demonstrate that variable concentration of ethanol consumption may increase alveolar bone loss in male rats, independent of dose used, associated with ligature-induce periodontitis in rats.
publishDate 2014
dc.date.none.fl_str_mv 2014-07-28
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
Research in rats
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/13029
10.15448/1980-6523.2014.3.13029
url https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/13029
identifier_str_mv 10.15448/1980-6523.2014.3.13029
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/13029/13369
dc.rights.driver.fl_str_mv Copyright (c) 2015 Revista Odonto Ciência (Journal of Dental Science)
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2015 Revista Odonto Ciência (Journal of Dental Science)
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
dc.source.none.fl_str_mv Revista Odonto Ciência; Vol. 29 No. 3 (2014); 76-80
Revista Odonto Ciência; v. 29 n. 3 (2014); 76-80
1980-6523
0102-9460
10.15448/1980-6523.2014.3
reponame:Revista odonto ciência (Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Revista odonto ciência (Online)
collection Revista odonto ciência (Online)
repository.name.fl_str_mv Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv ||odontociencia@pucrs.br
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