Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy

Detalhes bibliográficos
Autor(a) principal: Trucci, Victoria Martina
Data de Publicação: 2009
Outros Autores: Veeck, Elaine Bauer, Morosolli, Aline Rose
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista odonto ciência (Online)
Texto Completo: https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854
Resumo: Oral mucositis is a clinically relevant complication during the treatment of cancer patients. It is frequently seen in subjects receiving high doses of radiation therapy in the head-neck region, chemotherapy or a combination of these treatment modalities. Due to its complex pathophysiology, this type of inflammation can also affect the gastrointestinal tract, which has attracted the attention of medical professionals. The oncologic treatment does not distinguish the malignant cells from the normal epithelial cells of the mucosa because of their high-proliferative capacity. Thus, the mucosa becomes atrophic and more susceptible to trauma, allowing the development of inflammation and installation of secondary infections, which aggravates the patient clinical conditions and reduces the quality of life. The clinical management of mucositis includes preventive and palliative strategies. The preventive measures are the education and monitoring of patients in relation to their oral hygiene. The palliative measures should be adopted as early as the mucosa lesions occur and involve the use of oral solutions, topical anesthetics, analgesics and anti-inflammatory agents, lasertherapy, cryotherapy, and other clinical alternatives to control mucositis and provide comfort to the patient.
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spelling Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapyEstratégias atuais para o controle da mucosite bucal induzida por radioterapia ou quimioterapiamucositequimioterapiaradioterapiacâncer.Oral mucositis is a clinically relevant complication during the treatment of cancer patients. It is frequently seen in subjects receiving high doses of radiation therapy in the head-neck region, chemotherapy or a combination of these treatment modalities. Due to its complex pathophysiology, this type of inflammation can also affect the gastrointestinal tract, which has attracted the attention of medical professionals. The oncologic treatment does not distinguish the malignant cells from the normal epithelial cells of the mucosa because of their high-proliferative capacity. Thus, the mucosa becomes atrophic and more susceptible to trauma, allowing the development of inflammation and installation of secondary infections, which aggravates the patient clinical conditions and reduces the quality of life. The clinical management of mucositis includes preventive and palliative strategies. The preventive measures are the education and monitoring of patients in relation to their oral hygiene. The palliative measures should be adopted as early as the mucosa lesions occur and involve the use of oral solutions, topical anesthetics, analgesics and anti-inflammatory agents, lasertherapy, cryotherapy, and other clinical alternatives to control mucositis and provide comfort to the patient.A mucosite bucal é uma importante complicação do tratamento de pacientes oncológicos e, frequentemente, acomete uma parcela dos pacientes submetidos a altas doses de radiação na região de cabeça e pescoço e/ou quimioterapia ou à combinação de ambas. Em função de sua complexa fisiopatologia, esse tipo de inflamação também pode afetar a mucosa gastrintestinal e vem recebendo grande atenção por parte de cirurgiões-dentistas e médicos. Sabe-se que o tratamento oncológico, além de agir sobre as células malignas, também tem ação sobre as células epiteliais da mucosa, em razão de sua alta capacidade proliferativa. Dessa forma, a mucosa torna-se atrófica e suscetível a traumas, possibilitando o desenvolvimento da inflamação e a instalação de infecções secundárias, agravando o quadro clínico do paciente e reduzindo sua qualidade de vida. Há uma preocupação no controle da mucosite por meio de medidas preventivas para impedir seu desenvolvimento e de medidas paliativas, quando esta estiver instalada. Dentre as medidas preventivas estão a educação e o monitoramento do paciente visando o cuidado com a higiene bucal, enquanto as medidas paliativas envolvem o uso de soluções enxaguatórias, anestésicos tópicos, antiinflamatórios e analgésicos, laserterapia, crioterapia e outras alternativas. Essas medidas constituem estratégias que visam controlar a mucosite e propiciar melhor qualidade de vida ao paciente.EDIPUCRS - Editora Universitária da PUCRS2009-03-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Article. Invited Article.application/pdfhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854Revista Odonto Ciência; Vol. 24 No. 3 (2009); 309 - 314Revista Odonto Ciência; v. 24 n. 3 (2009); 309 - 3141980-65230102-9460reponame:Revista odonto ciência (Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSenghttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854/4518Trucci, Victoria MartinaVeeck, Elaine BauerMorosolli, Aline Roseinfo:eu-repo/semantics/openAccess2013-11-11T13:06:25Zoai:ojs.revistaseletronicas.pucrs.br:article/4854Revistahttps://revistaseletronicas.pucrs.br/ojs/index.php/foPRIhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/oai||odontociencia@pucrs.br1980-65230102-9460opendoar:2013-11-11T13:06:25Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy
Estratégias atuais para o controle da mucosite bucal induzida por radioterapia ou quimioterapia
title Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy
spellingShingle Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy
Trucci, Victoria Martina
mucosite
quimioterapia
radioterapia
câncer.
title_short Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy
title_full Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy
title_fullStr Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy
title_full_unstemmed Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy
title_sort Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy
author Trucci, Victoria Martina
author_facet Trucci, Victoria Martina
Veeck, Elaine Bauer
Morosolli, Aline Rose
author_role author
author2 Veeck, Elaine Bauer
Morosolli, Aline Rose
author2_role author
author
dc.contributor.author.fl_str_mv Trucci, Victoria Martina
Veeck, Elaine Bauer
Morosolli, Aline Rose
dc.subject.por.fl_str_mv mucosite
quimioterapia
radioterapia
câncer.
topic mucosite
quimioterapia
radioterapia
câncer.
description Oral mucositis is a clinically relevant complication during the treatment of cancer patients. It is frequently seen in subjects receiving high doses of radiation therapy in the head-neck region, chemotherapy or a combination of these treatment modalities. Due to its complex pathophysiology, this type of inflammation can also affect the gastrointestinal tract, which has attracted the attention of medical professionals. The oncologic treatment does not distinguish the malignant cells from the normal epithelial cells of the mucosa because of their high-proliferative capacity. Thus, the mucosa becomes atrophic and more susceptible to trauma, allowing the development of inflammation and installation of secondary infections, which aggravates the patient clinical conditions and reduces the quality of life. The clinical management of mucositis includes preventive and palliative strategies. The preventive measures are the education and monitoring of patients in relation to their oral hygiene. The palliative measures should be adopted as early as the mucosa lesions occur and involve the use of oral solutions, topical anesthetics, analgesics and anti-inflammatory agents, lasertherapy, cryotherapy, and other clinical alternatives to control mucositis and provide comfort to the patient.
publishDate 2009
dc.date.none.fl_str_mv 2009-03-06
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article. Invited Article.
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854
url https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854/4518
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
dc.source.none.fl_str_mv Revista Odonto Ciência; Vol. 24 No. 3 (2009); 309 - 314
Revista Odonto Ciência; v. 24 n. 3 (2009); 309 - 314
1980-6523
0102-9460
reponame:Revista odonto ciência (Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Revista odonto ciência (Online)
collection Revista odonto ciência (Online)
repository.name.fl_str_mv Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv ||odontociencia@pucrs.br
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