Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy
Autor(a) principal: | |
---|---|
Data de Publicação: | 2009 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista odonto ciência (Online) |
Texto Completo: | https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854 |
Resumo: | Oral mucositis is a clinically relevant complication during the treatment of cancer patients. It is frequently seen in subjects receiving high doses of radiation therapy in the head-neck region, chemotherapy or a combination of these treatment modalities. Due to its complex pathophysiology, this type of inflammation can also affect the gastrointestinal tract, which has attracted the attention of medical professionals. The oncologic treatment does not distinguish the malignant cells from the normal epithelial cells of the mucosa because of their high-proliferative capacity. Thus, the mucosa becomes atrophic and more susceptible to trauma, allowing the development of inflammation and installation of secondary infections, which aggravates the patient clinical conditions and reduces the quality of life. The clinical management of mucositis includes preventive and palliative strategies. The preventive measures are the education and monitoring of patients in relation to their oral hygiene. The palliative measures should be adopted as early as the mucosa lesions occur and involve the use of oral solutions, topical anesthetics, analgesics and anti-inflammatory agents, lasertherapy, cryotherapy, and other clinical alternatives to control mucositis and provide comfort to the patient. |
id |
PUC_RS-22_54743a8ea507c6bb1e6f5b29e1f9eb8c |
---|---|
oai_identifier_str |
oai:ojs.revistaseletronicas.pucrs.br:article/4854 |
network_acronym_str |
PUC_RS-22 |
network_name_str |
Revista odonto ciência (Online) |
repository_id_str |
|
spelling |
Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapyEstratégias atuais para o controle da mucosite bucal induzida por radioterapia ou quimioterapiamucositequimioterapiaradioterapiacâncer.Oral mucositis is a clinically relevant complication during the treatment of cancer patients. It is frequently seen in subjects receiving high doses of radiation therapy in the head-neck region, chemotherapy or a combination of these treatment modalities. Due to its complex pathophysiology, this type of inflammation can also affect the gastrointestinal tract, which has attracted the attention of medical professionals. The oncologic treatment does not distinguish the malignant cells from the normal epithelial cells of the mucosa because of their high-proliferative capacity. Thus, the mucosa becomes atrophic and more susceptible to trauma, allowing the development of inflammation and installation of secondary infections, which aggravates the patient clinical conditions and reduces the quality of life. The clinical management of mucositis includes preventive and palliative strategies. The preventive measures are the education and monitoring of patients in relation to their oral hygiene. The palliative measures should be adopted as early as the mucosa lesions occur and involve the use of oral solutions, topical anesthetics, analgesics and anti-inflammatory agents, lasertherapy, cryotherapy, and other clinical alternatives to control mucositis and provide comfort to the patient.A mucosite bucal é uma importante complicação do tratamento de pacientes oncológicos e, frequentemente, acomete uma parcela dos pacientes submetidos a altas doses de radiação na região de cabeça e pescoço e/ou quimioterapia ou à combinação de ambas. Em função de sua complexa fisiopatologia, esse tipo de inflamação também pode afetar a mucosa gastrintestinal e vem recebendo grande atenção por parte de cirurgiões-dentistas e médicos. Sabe-se que o tratamento oncológico, além de agir sobre as células malignas, também tem ação sobre as células epiteliais da mucosa, em razão de sua alta capacidade proliferativa. Dessa forma, a mucosa torna-se atrófica e suscetível a traumas, possibilitando o desenvolvimento da inflamação e a instalação de infecções secundárias, agravando o quadro clínico do paciente e reduzindo sua qualidade de vida. Há uma preocupação no controle da mucosite por meio de medidas preventivas para impedir seu desenvolvimento e de medidas paliativas, quando esta estiver instalada. Dentre as medidas preventivas estão a educação e o monitoramento do paciente visando o cuidado com a higiene bucal, enquanto as medidas paliativas envolvem o uso de soluções enxaguatórias, anestésicos tópicos, antiinflamatórios e analgésicos, laserterapia, crioterapia e outras alternativas. Essas medidas constituem estratégias que visam controlar a mucosite e propiciar melhor qualidade de vida ao paciente.EDIPUCRS - Editora Universitária da PUCRS2009-03-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Article. Invited Article.application/pdfhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854Revista Odonto Ciência; Vol. 24 No. 3 (2009); 309 - 314Revista Odonto Ciência; v. 24 n. 3 (2009); 309 - 3141980-65230102-9460reponame:Revista odonto ciência (Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSenghttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854/4518Trucci, Victoria MartinaVeeck, Elaine BauerMorosolli, Aline Roseinfo:eu-repo/semantics/openAccess2013-11-11T13:06:25Zoai:ojs.revistaseletronicas.pucrs.br:article/4854Revistahttps://revistaseletronicas.pucrs.br/ojs/index.php/foPRIhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/oai||odontociencia@pucrs.br1980-65230102-9460opendoar:2013-11-11T13:06:25Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.none.fl_str_mv |
Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy Estratégias atuais para o controle da mucosite bucal induzida por radioterapia ou quimioterapia |
title |
Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy |
spellingShingle |
Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy Trucci, Victoria Martina mucosite quimioterapia radioterapia câncer. |
title_short |
Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy |
title_full |
Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy |
title_fullStr |
Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy |
title_full_unstemmed |
Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy |
title_sort |
Current strategies for the management of oral mucositis induced by radiotherapy or chemotherapy |
author |
Trucci, Victoria Martina |
author_facet |
Trucci, Victoria Martina Veeck, Elaine Bauer Morosolli, Aline Rose |
author_role |
author |
author2 |
Veeck, Elaine Bauer Morosolli, Aline Rose |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Trucci, Victoria Martina Veeck, Elaine Bauer Morosolli, Aline Rose |
dc.subject.por.fl_str_mv |
mucosite quimioterapia radioterapia câncer. |
topic |
mucosite quimioterapia radioterapia câncer. |
description |
Oral mucositis is a clinically relevant complication during the treatment of cancer patients. It is frequently seen in subjects receiving high doses of radiation therapy in the head-neck region, chemotherapy or a combination of these treatment modalities. Due to its complex pathophysiology, this type of inflammation can also affect the gastrointestinal tract, which has attracted the attention of medical professionals. The oncologic treatment does not distinguish the malignant cells from the normal epithelial cells of the mucosa because of their high-proliferative capacity. Thus, the mucosa becomes atrophic and more susceptible to trauma, allowing the development of inflammation and installation of secondary infections, which aggravates the patient clinical conditions and reduces the quality of life. The clinical management of mucositis includes preventive and palliative strategies. The preventive measures are the education and monitoring of patients in relation to their oral hygiene. The palliative measures should be adopted as early as the mucosa lesions occur and involve the use of oral solutions, topical anesthetics, analgesics and anti-inflammatory agents, lasertherapy, cryotherapy, and other clinical alternatives to control mucositis and provide comfort to the patient. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-03-06 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article. Invited Article. |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854 |
url |
https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/4854/4518 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
EDIPUCRS - Editora Universitária da PUCRS |
publisher.none.fl_str_mv |
EDIPUCRS - Editora Universitária da PUCRS |
dc.source.none.fl_str_mv |
Revista Odonto Ciência; Vol. 24 No. 3 (2009); 309 - 314 Revista Odonto Ciência; v. 24 n. 3 (2009); 309 - 314 1980-6523 0102-9460 reponame:Revista odonto ciência (Online) instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
instname_str |
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
instacron_str |
PUC_RS |
institution |
PUC_RS |
reponame_str |
Revista odonto ciência (Online) |
collection |
Revista odonto ciência (Online) |
repository.name.fl_str_mv |
Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
repository.mail.fl_str_mv |
||odontociencia@pucrs.br |
_version_ |
1754820874844766208 |